Allosteric Changes in Solvent Accessibility Observed in Thrombin upon Active Site Occupation

Biochemistry

Volumn 43, Issue 18, 2004, Pages 5246-5255

  Croy, Carrie Hughes ^a   Koeppe, Julia R ^a   Bergqvist, Simon ^a   Komives, Elizabeth A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; KETONES; NEGATIVE IONS; PROTEINS;

ALLOSTERIC CHANGES; SOLVENT PROTECTION; SUBSTRATE BINDING;

BIOCHEMISTRY;

AMIDE; ANTITHROMBIN III; DEUTERIUM; FIBRINOGEN; HYDROGEN; PROTEIN C; SOLVENT; THROMBIN; THROMBOMODULIN;

ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; BLOOD CLOTTING; CATTLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME SUBSTRATE; HUMAN; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY;

ALLOSTERIC REGULATION; AMIDES; AMINO ACID CHLOROMETHYL KETONES; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATTLE; DEUTERIUM EXCHANGE MEASUREMENT; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; SERINE PROTEINASE INHIBITORS; SOLVENTS; SPECIES SPECIFICITY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SUBSTRATE SPECIFICITY; THROMBIN;

BOS TAURUS;

EID: 2442419061     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0499718     Document Type: Article

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