-
1
-
-
0025082684
-
Additivity of mutational effects in proteins
-
Wells, J A. 1990. Additivity of mutational effects in proteins. Biochemistry 29:8509-8517.
-
(1990)
Biochemistry
, vol.29
, pp. 8509-8517
-
-
Wells, J.A.1
-
2
-
-
0029826905
-
Hormone mimicry
-
Wells, J.A. 1996. Hormone mimicry. Science 273:449-450.
-
(1996)
Science
, vol.273
, pp. 449-450
-
-
Wells, J.A.1
-
3
-
-
0028916599
-
A hot spot of binding energy in a hormone-receptor interface
-
Clackson, T. and Wells, J.A. 1995. A hot spot of binding energy in a hormone-receptor interface. Science 267:383-386.
-
(1995)
Science
, vol.267
, pp. 383-386
-
-
Clackson, T.1
Wells, J.A.2
-
4
-
-
0029017360
-
Functional mapping of the surface residues of human thrombin
-
Tsiang, M., Jain, A.K., Dunn, K.E., Rojas, M.E., Leung, L.L.K., and Gibbs, C.S. 1995. Functional mapping of the surface residues of human thrombin. J. Biol. Chem. 270:16854-16863.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 16854-16863
-
-
Tsiang, M.1
Jain, A.K.2
Dunn, K.E.3
Rojas, M.E.4
Leung, L.L.K.5
Gibbs, C.S.6
-
5
-
-
0029992658
-
Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor Vila
-
Dickinson, C.D., Kelly, C.R., and Ruf, W. 1996. Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor Vila. Proc. Wail. Acad. Sci. USA 93:14379-14384.
-
(1996)
Proc. Wail. Acad. Sci. USA
, vol.93
, pp. 14379-14384
-
-
Dickinson, C.D.1
Kelly, C.R.2
Ruf, W.3
-
6
-
-
0024280501
-
Dissecting the catalytic triad of a serine protease
-
Carter, P. and Wells, J.A. 1988. Dissecting the catalytic triad of a serine protease. Nature 332:564-568.
-
(1988)
Nature
, vol.332
, pp. 564-568
-
-
Carter, P.1
Wells, J.A.2
-
7
-
-
0028914722
-
Structural basis of substrate specificity in serine proteinases
-
Perona, J.J. and Craik, C.S. 1995. Structural basis of substrate specificity in serine proteinases. Protein Sci. 4:337-360.
-
(1995)
Protein Sci
, vol.4
, pp. 337-360
-
-
Perona, J.J.1
Craik, C.S.2
-
8
-
-
0028884430
-
Identification of residues linked to the slow→fast transition of thrombin
-
Guinto, E.R., Vindigni, A., Ayala, Y, Dang, Q.D., and Di Cera, E. 1995. Identification of residues linked to the slow→fast transition of thrombin. Proc. Natl. Acad. Sci. USA 92:11185-11189.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11185-11189
-
-
Guinto, E.R.1
Vindigni, A.2
Ayala, Y.3
Dang, Q.D.4
Di Cera, E.5
-
9
-
-
0025004285
-
Random peptide libraries: A source of specific protein binding molecules
-
Devlin, J.J., Panganiban, L.C., and Devlin, P.E. 1990. Random peptide libraries: a source of specific protein binding molecules. Science 249:404-406.
-
(1990)
Science
, vol.249
, pp. 404-406
-
-
Devlin, J.J.1
Panganiban, L.C.2
Devlin, P.E.3
-
12
-
-
0031052393
-
Rational engineering of activity and specificity in a serine protease
-
Dang, Q.D., Guinto, E.R., and Di Cera, E. 1997. Rational engineering of activity and specificity in a serine protease. Nature Biotechnology 15:146-149.
-
(1997)
Nature Biotechnology
, vol.15
, pp. 146-149
-
-
Dang, Q.D.1
Guinto, E.R.2
Di Cera, E.3
-
13
-
-
0027050807
-
The refined 1.9-Å X-ray crystal structure of D-Phe-Pro-Arg-chloromethylketone-inhibited human a-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships
-
Bode, W., Turk, D., and Karshikov, A. 1992. The refined 1.9-Å X-ray crystal structure of D-Phe-Pro-Arg-chloromethylketone-inhibited human a-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships. Protein Sci. 1:426-471.
-
(1992)
Protein Sci
, vol.1
, pp. 426-471
-
-
Bode, W.1
Turk, D.2
Karshikov, A.3
-
15
-
-
0026548768
-
The interaction of thrombin with fibrinogen: A structural basis for its specificity
-
Stubbs, M., Oschkinat, H., Mayr, I., Huber, R., Angliker, H., Stone, S.R., and Bode, W. 1992. The interaction of thrombin with fibrinogen: a structural basis for its specificity. Eur. J. Biochem. 206:187-195.
-
(1992)
Eur. J. Biochem
, vol.206
, pp. 187-195
-
-
Stubbs, M.1
Oschkinat, H.2
Mayr, I.3
Huber, R.4
Angliker, H.5
Stone, S.R.6
Bode, W.7
-
16
-
-
0029785840
-
+-induced allosteric regulation of catalytic activity in serine proteases
-
+-induced allosteric regulation of catalytic activity in serine proteases. Proc. Natl. Acad. Sci. USA 93:10653-10656.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10653-10656
-
-
Dang, Q.D.1
Di Cera, E.2
-
17
-
-
0024791521
-
Crystal structure of bovine B-trypsin at 1.5 Å resolution in a crystal form with low molecular packing density
-
Bartunik, H.D., Summers, L.J., and Bartsch, H.H. 1989. Crystal structure of bovine B-trypsin at 1.5 Å resolution in a crystal form with low molecular packing density. J. Mol. Biol. 210:813-828.
-
(1989)
J. Mol. Biol
, vol.210
, pp. 813-828
-
-
Bartunik, H.D.1
Summers, L.J.2
Bartsch, H.H.3
-
18
-
-
0025060964
-
The chemical synthesis of the chro-mogenic substrates, H-D-Val-Leu-Lys-p-nitroanilide (S2251) and H-D-lle-Pro-Arg-p-nltroanilide (S2288)
-
Sharma, S.K. and Castellino, F.J. 1990. The chemical synthesis of the chro-mogenic substrates, H-D-Val-Leu-Lys-p-nitroanilide (S2251) and H-D-lle-Pro-Arg-p-nltroanilide (S2288). Thromb. Res. 57:127-138.
-
(1990)
Thromb. Res
, vol.57
, pp. 127-138
-
-
Sharma, S.K.1
Castellino, F.J.2
-
19
-
-
0030933791
-
Critical role of W60d in thrombin allostery
-
Guinto, E.R. and Di Cera, E. 1997. Critical role of W60d in thrombin allostery. Biophys. Chem. 64:103-109.
-
(1997)
Biophys. Chem
, vol.64
, pp. 103-109
-
-
Guinto, E.R.1
Di Cera, E.2
-
21
-
-
0026606829
-
Partial characterization of vertebrate prothrombin cDNAs: Amplification and sequence analysis of the B chain of thrombin from nine different species
-
Banfield, D.K. and MacGillivray, R.T.A. 1992. Partial characterization of vertebrate prothrombin cDNAs: amplification and sequence analysis of the B chain of thrombin from nine different species. Proc. Natl. Acad. Sci. USA 89:2779-2783.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2779-2783
-
-
Banfield, D.K.1
Macgillivray, R.T.A.2
-
22
-
-
0030895222
-
Design of highly potent noncovalent thrombin inhibitors that utilize a novel lipophilic binding pocket in the thrombin active site
-
Tucker, T.J., Lumma, W.C., Naylor-Olsen, A.M., Lewis, S.D., Lucas, R., Freidinger, R.M., et al. 1997. Design of highly potent noncovalent thrombin inhibitors that utilize a novel lipophilic binding pocket in the thrombin active site. J. Med. Chem. 40:830-832.
-
(1997)
J. Med. Chem
, vol.40
, pp. 830-832
-
-
Tucker, T.J.1
Lumma, W.C.2
Naylor-Olsen, A.M.3
Lewis, S.D.4
Lucas, R.5
Freidinger, R.M.6
-
23
-
-
0031050773
-
Molecular design and characterization of an α-thrombin inhibitor containing a novel P1 moiety
-
Malikayil, J.A., Burkhart, J.P., Schreuder, H.A., Broersma, R.J., Tardif, C, Kutcher, L.W., et al. 1997. Molecular design and characterization of an α-thrombin inhibitor containing a novel P1 moiety. Biochemistry 26:1034-1040.
-
(1997)
Biochemistry
, vol.26
, pp. 1034-1040
-
-
Malikayil, J.A.1
Burkhart, J.P.2
Schreuder, H.A.3
Broersma, R.J.4
Tardif, C.5
Kutcher, L.W.6
-
24
-
-
0028236301
-
Synthetic peptides and peptidomimetics as substrates and inhibitors of thrombin and other proteases in the blood coagulation system
-
Claeson, G. 1994. Synthetic peptides and peptidomimetics as substrates and inhibitors of thrombin and other proteases in the blood coagulation system. Blood Coagul. Fibrin. 5:411-436.
-
(1994)
Blood Coagul. Fibrin
, vol.5
, pp. 411-436
-
-
Claeson, G.1
-
25
-
-
0029147003
-
Core domain of hirudin from the leech Hirudinaria manillensis: Chemical synthesis, purification, and characterization of a Trp3 analog of fragment 1-47
-
De Filippis, V, Vindigni, A., Altichieri, L., and Fontana, A. 1995. Core domain of hirudin from the leech Hirudinaria manillensis: chemical synthesis, purification, and characterization of a Trp3 analog of fragment 1-47. Biochemistry 34:9552-9564.
-
(1995)
Biochemistry
, vol.34
, pp. 9552-9564
-
-
De Filippis, V.1
Vindigni, A.2
Altichieri, L.3
Fontana, A.4
-
26
-
-
0030948651
-
Energetics of thrombin-thrombomodulin interaction
-
Vindigni, A., White, C.E., Komives, E.A., and Di Cera, E. 1997. Energetics of thrombin-thrombomodulin interaction. Biochemistry 36:6674-6681.
-
(1997)
Biochemistry
, vol.36
, pp. 6674-6681
-
-
Vindigni, A.1
White, C.E.2
Komives, E.A.3
Di Cera, E.4
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