Signal transduction of p53-independent apoptotic pathway induced by hexavalent chromium in U937 cells

Toxicology and Applied Pharmacology

Volumn 197, Issue 2, 2004, Pages 96-106

  Hayashi, Yoko ^a   Kondo, Takashi ^a   Zhao, Qing Li ^a   Ogawa, Ryohei ^a   Cui, Zheng Guo ^a   Feril Jr , Loreto B ^a   Teranishi, Hidetoyo ^a   Kasuya, Minoru ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Ca2+ i; Apoptosis; Calcium ion; Calpain; Cr(III); Cr(VI); Hexavalent chromium; hexavalent chromium; intracellular Ca2+ concentration; Mitochondria caspase pathway; N acetyl L cysteine; p53 independent pathway; trivalent chromium

Indexed keywords

ACETYLCYSTEINE; CALCIUM ION; CALPAIN; CALPASTATIN; CASPASE 3; CHELATING AGENT; CHROMIUM; DNA FRAGMENT; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FAS ANTIGEN; HYDROXYL RADICAL; JANUS KINASE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL COUNT; CELL CYCLE; CELL CYCLE G2 PHASE; CELL MUTANT; CHELATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMAGING; MEMBRANE POTENTIAL; MITOCHONDRION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPIN TRAPPING;

ANTIGENS, CD95; APOPTOSIS; BLOTTING, WESTERN; CALCIUM SIGNALING; CALPAIN; CELL CYCLE; CHELATING AGENTS; CHROMIUM; DNA FRAGMENTATION; EGTAZIC ACID; FREE RADICALS; GENES, P53; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPID PEROXIDATION; MAP KINASE KINASE 4; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; SIGNAL TRANSDUCTION; U937 CELLS;

EID: 2442417777     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2004.02.011     Document Type: Article

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