MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (β-D-glucuronate)

Biochemical Pharmacology

Volumn 70, Issue 7, 2005, Pages 1056-1065

  Noguchi, Tomohiro ^a   Ren, Xiao Qin ^a,d   Aoki, Shunji ^b   Igarashi, Yoshinobu ^c   Che, Xiao Fang ^a   Nakajima, Yuichi ^a   Takahashi, Homare ^a   Mitsuo, Ryoichi ^a   Tsujikawa, Kazutake ^b   Sumizawa, Tomoyuki ^a   Haraguchi, Misako ^a   Kobayashi, Motomasa ^b   Goto, Susumu ^c   Kanehisa, Minoru ^c   Aikou, Takashi ^a   Akiyama, Shin Ichi ^a   Furukawa, Tatsuhiko ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

ABC transporter; Drug resistance; E217 G; GSH; L0; LTC 4; MRP1; SN 38

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; AZIDE; ESTRADIOL 17 GLUCURONIDE; GLUTATHIONE; IRINOTECAN; LEUKOTRIENE C4; MULTIDRUG RESISTANCE PROTEIN 1; 7-ETHYL-10-HYDROXYCAMPTOTHECIN; CAMPTOTHECIN; DRUG DERIVATIVE; ESTRADIOL; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; PRIMER DNA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL LABELING; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG TRANSPORT; HUMAN; HUMAN CELL; INDUCED MUTATION; MEMBRANE VESICLE; PREDICTION; PRIORITY JOURNAL; PROTEIN TRANSPORT; CELL LINE; CHEMISTRY; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEOTIDE SEQUENCE; PHOTOAFFINITY LABELING; PHYSIOLOGY;

BASE SEQUENCE; CAMPTOTHECIN; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA PRIMERS; ESTRADIOL; HUMANS; LEUKOTRIENE C4; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PHOTOAFFINITY LABELS;

EID: 24344487415     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.06.025     Document Type: Article

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