α2-Adrenergic agonists antagonise the anxiolytic-like effect of antidepressants in the four-plate test in mice

Behavioural Brain Research

Volumn 164, Issue 1, 2005, Pages 17-28

  Massé, Fabienne ^a   Hascoët, Martine ^a   Bourin, Michel ^a  

^a UNIVERSITÉ DE NANTES   (France)

Author keywords

2 Adrenoceptor agonists; Four plate test; Mice; SNRIs; SSRIs

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; CITALOPRAM; CLONIDINE; GUANABENZ; MILNACIPRAN; NORADRENALIN UPTAKE INHIBITOR; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; VENLAFAXINE; ADRENERGIC RECEPTOR AFFECTING AGENT; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLOHEXANOL DERIVATIVE; CYCLOPROPANE DERIVATIVE;

ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; LOCOMOTION; MALE; MOUSE; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; TRANQUILIZING ACTIVITY; TREATMENT FAILURE; ANIMAL; ANXIETY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; MOTOR ACTIVITY; NONPARAMETRIC TEST; PUNISHMENT;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC UPTAKE INHIBITORS; ANIMALS; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS; ANXIETY; CITALOPRAM; CLONIDINE; CYCLOHEXANOLS; CYCLOPROPANES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; GUANABENZ; MALE; MICE; MOTOR ACTIVITY; PAROXETINE; PUNISHMENT; SEROTONIN UPTAKE INHIBITORS; STATISTICS, NONPARAMETRIC;

EID: 24344472685     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2005.05.017     Document Type: Article

References (68)

1. 2 receptor regulation of extracellular GABA levels in the prefrontal cortex Neuropsychopharmacology 20 1999 92 96
2. A. Adell, and F. Artigas Regulation of the release of 5-hydroxytryptamine in the median raphe nucleus of the rat by catecholaminergic afferents Eur J Neurosci 11 1999 2305 2311
3. C. Allgulander, R. Mangano, J. Zhang, A.A. Dahl, U. Lepola, and I. Sjodin Efficacy of Venlafaxine ER in patients with social anxiety disorder: a double-blind, placebo-controlled, parallel-group comparison with paroxetine Hum Psychopharmacol 19 2004 387 396
4. M. Amargos-Bosch, A. Adell, A. Bortolozzi, and F. Artigas Stimulation of alpha1-adrenoceptors in the rat medial prefrontal cortex increases the local in vivo 5-hydroxytryptamine release: reversal by antipsychotic drugs J Neurochem 87 2003 831 842
5. C. Aron, P. Simon, C. Larousse, and J.R. Boissier Evaluation of a rapid technique for detecting minor tranquilizers Neuropharmacology 10 1971 459 469
6. 1A receptor antagonist WAY-100635 Int J Neuropsychopharmacol 4 2001 399 408
7. T. Bandoh, M. Hayashi, K. Ino, S. Takada, Z. Ushizawa, and K. Hoshi Acute effect of milnacipran on the relationship between the locus coeruleus noradrenergic and dorsal raphe serotonergic neuronal transmitters Eur Neuropsychopharmacol 14 2004 471 478
8. C. Belzung, and F. Berton Further pharmacological validation of the BALB/c neophobia in the free exploratory paradigm as an animal model of trait anxiety Behav Pharmacol 8 1997 541 548
9. C.E. Beyer, S. Boikess, B. Luo, and L.A. Dawson Comparison of the effects of antidepressants in norepinephrine and serotonin concentrations in the rat frontal cortex: an in-vivo microdialysis study J Psychopharmacol 16 4 2002 297 304
10. J.R. Boissier, and P. Simon Action of caffeine on the spontaneous motility of the mouse Arch Int Pharmacodyn Ther 158 1965 212 221
11. 2-adrenoceptors Neuropsychopharmacol 28 2003 421 434
12. F. Borsini, J. Podhorna, and D. Marazziti Do animal models of anxiety predict anxiolytic-like effects of antidepressants? Psychopharmacology (Berlin) 163 2002 121 141
13. M. Bourin, M.C. Colombel, M. Malinge, and J. Bradwejn Clonidine as a sensitizing agent in the forced swimming test for revealing antidepressant activity J Psychiatry Neurosci 16 1991 199 203
14. M. Bourin, M. Hascoët, B. Mansouri, M.C. Colombel, and J. Bradwejn Comparison of behavioral effects after single and repeated administrations of four benzodiazepines in three mice behavioral models J Psychiatry Neurosci 17 1992 72 77
15. M. Bourin, M. Hascoet, M.C. Colombel, J.P. Redrobe, and G.B. Baker Differential effects of clonidine, lithium and quinine in the forced swimming test in mice for antidepressants: possible roles of serotoninergic systems Eur Neuropsychopharmacol 6 1996 231 236
16. M. Bourin Use of paroxetine for the treatment of depression and anxiety disorders in the elderly: A review Hum Psychopharmacol Clin Exp 18 2003 185 190
17. M. Bourin, F. Massé, E. Dailly, and M. Hascoet Mechanism of action of milnacipran in anxiety in the four-plate test in mice Pharmacol Biochem Behav 81 2005 645 656
18. M. Cecchi, H. Khoshbouei, M. Javors, and D.A. Morilak Modulatory effects of norepinephrine in the lateral bed nucleus of the stria terminalis on behavioral and neuroendocrine responses to acute stress Neuroscience 112 2002 13 21
19. 2C receptors in the anti-immobility effects of antidepressants in the forced swimming test in mice Eur Neuropsychopharmacol 11 2001 145 152
20. 2-adrenoceptor mediation Psychopharmacology (Berlin) 118 1995 425 436
21. 2A receptor antagonists inhibit potassium-stimulated gamma-aminobutyric acid release in rat frontal cortex Eur J Pharmacol 309 1996 25 31
22. J.F. Cryan, O.F. O'Leary, S.H. Jin, J.C. Friedland, M. Ouyang, and B.R. Hirsch Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors Proc Natl Acad Sci USA 101 2004 8186 8191
23. D.J. David, M. Bourin, G. Jego, C. Przybylski, P. Jolliet, and A.M. Gardier Effects of acute treatment with paroxetine, citalopram and venlafaxine in vivo on noradrenaline and serotonin outflow: a microdialysis study in Swiss mice Br J Pharmacol 140 2003 1128 1136
24. 2C receptors Neuropharmacology 39 2000 1114 1117
25. T. Dennis, R. L'Heureux, C. Carter, and B. Scatton Presynaptic alpha-2 adrenoceptors play a major role in the effects of idazoxan on cortical noradrenaline release (as measured by in vivo dialysis) in the rat J Pharmacol Exp Ther 241 1987 642 649
26. E.W. Fish, S. Faccidomo, S. Gupta, and K.A. Miczek Anxiolytic-like effects of escitalopram, citalopram, and R-citalopram in maternally separated mouse pups J Pharmacol Exp Ther 308 2004 474 480
27. Fontana DJ, Schefke DM, Commissaris RL. Acute versus chronic clonidine treatment effects on conflict behavior in the rat. Behav Pharmacol 1989;1:201-8.
28. N. French Alpha 2-adrenoceptors and I2 sites in the mammalian central nervous system Pharmacol Ther 68 1995 175 208
29. R. Galvez, M.H. Mesches, and J.L. McGaugh Norepinephrine release in the amygdala in response to footshock stimulation Neurobiol Learn Mem 66 1996 253 257
30. G. Griebel, J.L. Moreau, F. Jenck, R. Misslin, and J.R. Martin Acute and chronic treatment with 5-HT reuptake inhibitors differentially modulate emotional responses in anxiety models in rodents Psychopharmacology (Berlin) 113 1994 463 470
31. N. Haddjeri, P. Blier, and C. de Montigny Effect of the alpha-2 adrenoceptor antagonist mirtazapine on the 5-hydroxytryptamine system in the rat brain J Pharmacol Exp Ther 277 1996 861 871
32. E. Hajos-Korcsok, S.F. McTavish, and T. Sharp Effect of a selective 5-hydroxytryptamine reuptake inhibitor on brain extracellular noradrenaline: microdialysis studies using paroxetine Eur J Pharmacol 407 2000 101 107
33. S.L. Handley, and S. Mithani Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of 'fear'-motivated behaviour Naunyn Schmiedebergs Arch Pharmacol 327 1984 1 5
34. M. Hascoet, M. Bourin, M.C. Colombel, A.J. Fiocco, and G.B. Baker Anxiolytic-like effects of antidepressants after acute administration in a four-plate test in mice Pharmacol Biochem Behav 65 2000 339 344
35. S. Hashimoto, T. Inoue, and T. Koyama Serotonin reuptake inhibitors reduce conditioned fear stress-induced freezing behavior in rats Psychopharmacology (Berlin) 123 1996 182 186
36. T. Inoue, S. Hashimoto, K. Tsuchiya, T. Izumi, T. Ohmori, and T. Koyama Effect of citalopram, a selective serotonin reuptake inhibitor, on the acquisition of conditioned freezing Eur J Pharmacol 311 1996 1 6
37. S. La Marca, and R.W. Dunn The alpha-2 antagonists idazoxan and rauwolscine but not yohimbine or piperoxan are anxiolytic in the Vogel lick-shock conflict paradigm following intravenous administration Life Sci 54 1994 PL179 PL184
38. S. Lightowler, G.A. Kennett, I.J. Williamson, T.P. Blackburn, and I.F. Tulloch Anxiolytic-like effect of paroxetine in a rat social interaction test Pharmacol Biochem Behav 49 1994 281 285
39. 1A agonists Behav Pharmacol 5 1994 42 51
40. M. Malinge, M. Bourin, M.C. Colombel, and C. Larousse Additive effects of clonidine and antidepressant drugs in the mouse forced-swimming test Psychopharmacology (Berlin) 96 1988 104 109
41. Y. Mateo, J.A. Ruiz-Ortega, J. Pineda, L. Ugedo, and J.J. Meana Inhibition of 5-hydroxytryptamine reuptake by the antidepressant citalopram in the locus coeruleus modulates the rat brain noradrenergic transmission in vivo Neuropharmacology 39 2000 2036 2043
42. V. Matto, J. Harro, and L. Allikmets The effects of cholecystokinin A and B receptor antagonists, devazepide and L 365260, on citalopram-induced decrease of exploratory behaviour in rat J Physiol Pharmacol 47 1996 661 669
43. M.J. Millan The neurobiology and control of anxious states Prog Neurobiol 70 2003 83 244
44. M.J. Millan, F. Lejeune, A. Gobert, M. Brocco, A. Auclair, and C. Bosc S18616, a highly potent spiroimidazoline agonist at alpha(2)-adrenoceptors. II. Influence on monoaminergic transmission, motor function, and anxiety in comparison with dexmedetomidine and clonidine J Pharmacol Exp Ther 295 2000 1206 1222
45. J. Miyamoto, M. Tsuji, H. Takeda, M. Ohzeki, H. Nawa, and T. Matsumiya Characterization of the anxiolytic-like effects of fluvoxamine, milnacipran and risperidone in mice using the conditioned fear stress paradigm Eur J Pharmacol 504 2004 97 103
46. 2 receptor subtypes in the mechanism of action of antidepressants in the four plates test Psychopharmacology (Berlin) 179 2005 418 429
47. D. Nutt Anxiety and depression: individual entities or two sides of same coin? Int J Psychiatry Clin Pract 8 2004 19 24
48. M.F. Piacentini, R. Clinckers, R. Meeusen, S. Sarre, G. Ebinger, and Y. Michotte Effects of venlafaxine on extracellular 5-HT, dopamine and noradrenaline in the hippocampus and on peripheral hormone concentrations in the rat in vivo Life Sci 73 2003 2433 2442
49. G.L. Quirarte, R. Galvez, B. Roozendaal, and J.L. McGaugh Norepinephrine release in the amygdala in response to footshock and opioid peptidergic drugs Brain Res 808 1998 134 140
50. J.P. Redrobe, and M. Bourin Effects of pretreatment with clonidine, lithium and quinine on the activities of antidepressant drugs in the mouse tail suspension test Fundam Clin Pharmacol 11 1997 381 386
51. 2A/2C antagonists and 8-OH-DPAT in the mouse forced swimming test Eur Neuropsychopharmacol 8 1998 169 173
52. T.J. Sajdyk, J.S. Katner, and A. Shekhar Monoamines in the dorsomedial hypothalamus of rats following exposure to different tests of "anxiety" Prog Neuropsychopharmacol Biol Psychiatry 21 1997 193 209
53. C. Sanchez, and J. Hyttel Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding Cell Mol Neurobiol 19 1999 467 489
54. R. Schreiber, C. Melon, and J. De Vry The role of 5-HT receptor subtypes in the anxiolytic effects of selective serotonin reuptake inhibitors in the rat ultrasonic vocalization test Psychopharmacology (Berlin) 135 1998 383 391
55. S. Sevy, G.N. Papadimitriou, D.W. Surmont, S. Goldman, and J. Mendlewicz Noradrenergic function in generalized anxiety disorder, major depressive disorder, and healthy subjects Biol Psychiatry 25 1989 141 152
56. D. Sheehan, G.C. Dunbar, and D.L. Fuell The effect of paroxetine on anxiety and agitation associated with depression Psychopharmacol Bull 28 1992 139 143
57. 2A-adrenoceptors administered into the region of the locus ceruleus on behaviors in plus-maze and sexual behavior tests in sham-operated and castrated male rats J Neurosci 21 2001 726 731
58. G.T. Shishkina, T.S. Kalinina, N.Y. Sournina, D.G. Saharov, V.F. Kobzev, and N.N. Dygalo Effects of antisense oligodeoxynucleotide to the alpha2A-adrenoceptors on the plasma corticosterone level and on elevated plus-maze behavior in rats Psychoneuroendocrinology 27 2002 593 601
59. T. Skrebuhhova, L. Allikmets, and V. Matto [3H]-ketanserin binding and elevated plus-maze behavior after chronic antidepressant treatment in DSP-4 and p-CPA pretreated rats: evidence for partial involvement of 5-HT receptors Meth Find Exp Clin Pharmacol 21 1999 483 490
60. A. Soderpalm, O. Blomqvist, and B. Soderpalm The yohimbine-induced anticonflict effect in the rat. Part I. Involvement of noradrenergic, serotonergic and endozepinergic(?) mechanisms J Neural Transm Gen Sect 100 1995 175 189
61. T.H. Svensson, B.S. Bunney, and G.K. Aghajanian Inhibition of both noradrenergic and serotonergic neurons in brain by the alpha-adrenergic agonist clonidine Brain Res 92 1975 291 306
62. T. Tanaka, H. Yokoo, K. Mizoguchi, M. Yoshida, A. Tsuda, and M. Tanaka Noradrenaline release in the rat amygdala is increased by stress: studies with intracerebral microdialysis Brain Res 544 1991 174 176
63. I. Varia, and F. Rauscher Treatment of generalized anxiety disorder with citalopram Int Clin Psychopharmacol 17 2002 103 107
64. P. Venault, F. Jacquot, E. Save, S. Sara, and G. Chapouthier Anxiogenic-like effects of yohimbine and idazoxan in two behavioral situations in mice Life Sci 52 1993 639 645
65. E.S. Vizi, and J.P. Kiss Neurochemistry and pharmacology of the major hippocampal transmitter systems: synaptic and nonsynaptic interactions Hippocampus 8 1998 566 607
66. P. Weikop, J. Kehr, and J. Scheel-Kruger The role of alpha1- and alpha2-adrenoreceptors on venlafaxine-induced elevation of extracellular serotonin, noradrenaline and dopamine levels in the rat prefrontal cortex and hippocampus J Psychopharmacol 18 2004 395 403
67. I.K. Wright, M. Heaton, N. Upton, and C.A. Marsden Comparison of acute and chronic treatment of various serotonergic agents with those of diazepam and idazoxan in the rat elevated X-maze Psychopharmacology (Berlin) 107 1992 405 414
68. M.R. Zarrindast, H. Homayoun, A. Babaie, A. Etminani, and B. Gharib Involvement of adrenergic and cholinergic systems in nicotine-induced anxiogenesis in mice Eur J Pharmacol 407 2000 145 158