Inhibition of 5-hydroxytryptamine reuptake by the antidepressant citalopram in the locus coeruleus modulates the rat brain noradrenergic transmission in vivo

Neuropharmacology

Volumn 39, Issue 11, 2000, Pages 2036-2043

  Mateo, Yolanda ^a   Ruiz Ortega, J Angel ^a   Pineda, Joseba ^a   Ugedo, Luisa ^a   Meana, J Javier ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

2 Adrenoceptors; Antidepressants; Locus coeruleus; Microdialysis; Noradrenaline; Serotonin (5 HT)

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIDEPRESSANT AGENT; CITALOPRAM; FENCLONINE; NAPHTHYRIDINE DERIVATIVE; NORADRENALIN; SEROTONIN; SEROTONIN UPTAKE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY NEUROSIS; ARTICLE; CINGULATE GYRUS; CONTROLLED STUDY; DEPRESSION; DRUG MECHANISM; LOCUS CERULEUS; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; RAT; SEROTONIN UPTAKE; SEROTONINERGIC SYSTEM;

ANIMALS; CITALOPRAM; LOCUS COERULEUS; MICRODIALYSIS; NEURONS; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; SEROTONIN UPTAKE INHIBITORS;

EID: 0033849022     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(00)00041-1     Document Type: Article

References (44)

1. Adell A., Artigas F. Differential effects of clomipramine given locally or systemically on extracellular 5-hydroxytryptamine in raphe nuclei and frontal cortex. Naunyn Schmiedeberg's Archives of Pharmacology. 343:1991;237-244.
2. Aghajanian G.K., Andrade R. Electrophysiology of 5-HT receptors. Baumgarten H.G., Göthert M. Serotoninergic Neurons and 5-HT Receptors in the CNS. Handbook of Experimental Pharmacology. vol. 129:1997;499-535 Springer Verlag, Berlin.
3. Aston-Jones G., Akaoka H., Charlèty P., Chouvet G. Serotonin selectively attenuates glutamate-evoked activation of noradrenergic locus coeruleus neurons. Journal of Neuroscience. 11:1991;760-769.
4. 1A receptor in primate brain neurons and glial cells. Neuropsychopharmacology. 14:1996;35-46.
5. Berridge C.W., Abercrombie E.D. Relationship between locus coeruleus discharge rates and rates of norepinephrine release within neocortex as assessed by in vivo microdialysis. Neuroscience. 93:1999;1263-1270.
6. 1B receptors. Journal of Pharmacology and Experimental Therapeutics. 250:1989;37-43.
7. 2-adrenoceptor antagonist. British Journal of Pharmacology. 108:1993;516-525.
8. Cedarbaum J.M., Aghajanian G.K. Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the α-antagonist piperoxane. Brain Research. 112:1976;413-419.
9. 2 agonist augments γ-aminobutyric acid and excitatory amino acid inputs to noradrenergic locus coeruleus neurons. Neuroscience. 54:1993;409-420.
10. Crespi F., Buda M., McRae-Degueurce A., Pujol J.-F. Alteration of tyrosine hydroxylase activity in the locus coeruleus after administration of p-chlorophenylalanine. Brain Research. 191:1980;501-509.
11. Curzon G., Fernando J.C.R., Marsden C.A. 5-Hydroxytryptamine: the effects of impaired synthesis on its metabolism and release in rat. British Journal of Pharmacology. 63:1978;627-634.
12. Engberg G. Citalopram and 8-OH-DPAT attenuate nicotine-induced excitation of central noradrenaline neurons. Journal of Neural Transmission. 89:1992;149-154.
13. 1A-autoreceptors regulating monoamine synthesis in the rat brain in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 360:1999;135-143.
14. Florin-Lechner S.M., Druhan J.P., Aston-Jones G., Valentino R.J. Enhanced norepinephrine release in prefrontal cortex with burst stimulation of the locus coeruleus. Brain Research. 742:1996;89-97.
15. 2-Adrenergic receptor blockade markedly potentiates duloxetine- and fluoxetine-induced increases in noradrenaline, dopamine, and serotonin levels in the frontal cortex of freely moving rats. Journal of Neurochemistry. 69:1997;2616-2619.
16. Haddjeri N., de Montigny C., Blier P. Modulation of the firing activity of noradrenergic neurones in the rat locus coeruleus by the 5-hydroxytryptamine system. British Journal of Pharmacology. 120:1997;865-875.
17. 3H]imipramine localization and relationship to serotonin transporter. Journal of Pharmacology and Experimental Therapeutics. 252:1990;410-418.
18. Hughes Z.A., Stanford S.C. Evidence from microdialysis and synaptosomal studies of rat cortex for noradrenaline uptake sites with different sensitivities to SSRIs. British Journal of Pharmacology. 124:1998;1141-1148.
19. Invernizzi R., Belli S., Samanin R. Citalopram's ability to increase the extracellular concentrations of serotonin in the dorsal raphe prevents the drug's effect in the frontal cortex. Brain Research. 584:1992;322-324.
20. Jacobs B.L., Azmitia E.C. Structure and function of the brain serotonin system. Physiological Reviews. 72:1992;165-229.
21. Koe B.K., Weissman A. p-Chlorophenylalanine: a specific depletor of brain serotonin. Journal of Pharmacology and Experimental Therapeutics. 154:1966;499-516.
22. 2-adrenoceptors in the locus coeruleus are involved in the in vivo modulation of cortical noradrenaline release by the antidepressant desipramine. Journal of Neurochemistry. 71:1998;790-798.
23. 2-adrenoceptor subtype located in rat locus coeruleus that modulates cortical noradrenaline release in vivo. European Journal of Pharmacology. 379:1999;53-57.
24. 3H]noradrenaline in rat brain limbic structures. European Journal of Pharmacology. 256:1994;269-279.
25. Mongeau R., Blier P., de Montigny C. The serotonergic and noradrenergic systems of the hippocampus: their interactions and the effects of antidepressant treatments. Brain Research Reviews. 23:1997;145-195.
26. O'Connell M.T., Portas C.M., Sarna G.S., Curzon G. Effect of p-chlorophenylalanine on release of 5-hydroxytryptamine from the rat frontal cortex in vivo. British Journal of Pharmacology. 102:1991;831-836.
27. Owens M.J., Morgan W.N., Plott S.J., Nemeroff C.B. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. Journal of Pharmacology and Experimental Therapeutics. 283:1997;1305-1322.
28. Palij P., Stamford J.A. Real-time monitoring of endogenous noradrenaline release in rat brain slices using fast cyclic voltammetry: 3. Selective detection of noradrenaline efflux in the locus coeruleus. Brain Research. 634:1994;275-282.
29. Park D.H., Stone D.M., Baker H., Kim K.S., Joh T.H. Early induction of rat brain tryptophan hydroxylase (TPH) mRNA following parachlorophenylalanine (PCPA) treatment. Molecular Brain Research. 22:1994;20-28.
30. Pineda J., Ugedo L., García-Sevilla J.A. Stimulatory effects of clonidine, cirazoline and rilmenidine on locus coeruleus noradrenergic neurones: possible involvement of imidazoline-preferring receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 348:1993;134-140.
31. Pitts D.K., Marwah J. Electrophysiological actions of cocaine on noradrenergic neurons in rat locus coeruleus. Journal of Pharmacology and Experimental Therapeutics. 240:1987;345-351.
32. Quintin L., Hilaire G., Pujol J.-F. Variations in 3,4-dihydroxyphenylacetic acid concentration are correlated to single cell firing changes in the rat locus coeruleus. Neuroscience. 18:1986;889-899.
33. Redfern W.S., MacKinnon A.C., Brown C.M., Martin A.B., Kilpatrick A.T., Clague R.U., Spedding M. Modulation of central noradrenergic function by RS-15385-197. British Journal of Pharmacology. 108:1993;526-533.
34. Segal M. Serotonergic innervation of the locus coeruleus from the dorsal raphe and its action on responses to noxious stimuli. Journal of Physiology. 286:1979;401-415.
35. Shiekhattar R., Aston-Jones G. Sensory responsiveness of brain noradrenergic neurons is modulated by endogenous brain serotonin. Brain Research. 623:1993;72-76.
36. Singewald N., Kaehler S.T., Hemeida R., Philippu A. Release of serotonin in the rat locus coeruleus: effects of cardiovascular, stressful and noxious stimuli. European Journal of Neuroscience. 9:1997;556-562.
37. Singewald N., Philippu A. Release of neurotransmitters in the locus coeruleus. Progress in Neurobiology. 56:1998;237-267.
38. Stanford S.C. Prozac: panacea or puzzle? Trends in Pharmacological Science. 17:1996;150-154.
39. Svensson T.H., Bunney B.S., Aghajanian G.K. Inhibition of both NA and 5-HT neurons in brain by the α-adrenergic agonist clonidine. Brain Research. 92:1975;291-306.
40. Szabo S.T., de Montigny C., Blier P. Modulation of noradrenergic neuronal firing by selective serotonin reuptake blockers. British Journal of Pharmacology. 126:1999;568-571.
41. Tatsumi M., Groshan K., Blakely R.D., Richelson E. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. European Journal of Pharmacology. 340:1997;249-258.
42. Thomas D.N., Post R.M., Pert A. Focal and systemic cocaine differentially affect extracellular norepinephrine in the locus coeruleus, frontal cortex and hippocampus of the anaesthetized rat. Brain Research. 645:1994;135-142.
43. Van Gaalen M., Kawahara H., Kawahara Y., Westerink B.H.C. The locus coeruleus noradrenergic system in the rat brain studied by dual-probe microdialysis. Brain Research. 763:1997;56-62.
44. 1A binding sites on serotonin containing neurons in the raphe dorsalis and raphe centralis nuclei of the rat brain. Neurochemistry International. 7:1985;1061-1072.