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Volumn 277, Issue 2, 1996, Pages 861-871

Effect of the alpha-2 adrenoceptor antagonist mirtazapine on the 5-hydroxytryptamine system in the rat brain

Author keywords

[No Author keywords available]

Indexed keywords

5,7 DIHYDROXYTRYPTAMINE; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIDEPRESSANT AGENT; CLONIDINE; DESIPRAMINE; FLUOXETINE; LYSERGIDE; METERGOLINE; MIRTAZAPINE; OXIDOPAMINE; PINDOLOL; SEROTONIN 1A ANTAGONIST;

EID: 0030431697     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (130)

References (54)
  • 1
    • 0018066653 scopus 로고
    • Feedback regulation of central monoaminergic neurons: Evidence from single cell recording studies
    • ed. by M. B. H. Youdim, W. Lovenberg, D. F. Sharman and J. R Lagnado, J. Wiley and Sons, New York
    • AGHAJANIAN, G. K.: Feedback regulation of central monoaminergic neurons: Evidence from single cell recording studies. In Essays in Neurochemistry and Neuropharmacology, ed. by M. B. H. Youdim, W. Lovenberg, D. F. Sharman and J. R Lagnado, pp, 2-32, J. Wiley and Sons, New York, 1978.
    • (1978) Essays in Neurochemistry and Neuropharmacology , pp. 2-32
    • Aghajanian, G.K.1
  • 2
    • 0017734626 scopus 로고
    • Locus ceruleus to dorsal raphe input examined by electrophysiological and morphological methods
    • ANDERSON, C. D., PASQUIER, D. A., FORBES, W. B. AND MORGANE, P. J.: Locus ceruleus to dorsal raphe input examined by electrophysiological and morphological methods. Brain. Res. Bull. 2: 209-221, 1977.
    • (1977) Brain. Res. Bull. , vol.2 , pp. 209-221
    • Anderson, C.D.1    Pasquier, D.A.2    Forbes, W.B.3    Morgane, P.J.4
  • 3
    • 0018853233 scopus 로고
    • Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists
    • BARABAN, J. M. AND ACHAJANIAN, G. K.: Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists. Neuropharmacology 19: 355-363, 1980.
    • (1980) Neuropharmacology , vol.19 , pp. 355-363
    • Baraban, J.M.1    Achajanian, G.K.2
  • 4
    • 0019365408 scopus 로고
    • Noradrenergic innervation of serotoninergic neurons in the dorsal raphe: Demonstration by electron microscopic autoradiography
    • BARABAN, J M. AND AGHAJANIAN, G. K.: Noradrenergic innervation of serotoninergic neurons in the dorsal raphe: Demonstration by electron microscopic autoradiography. Brain Res. 204: 1-11, 1981.
    • (1981) Brain Res. , vol.204 , pp. 1-11
    • Baraban, J.M.1    Aghajanian, G.K.2
  • 5
    • 0027766820 scopus 로고
    • Histamine releases norepinephrine in the paraventricular nucleus/anterior hypothalamus of the conscious rat
    • BEALER, S. L.: Histamine releases norepinephrine in the paraventricular nucleus/anterior hypothalamus of the conscious rat. J. Pharmacol. Exp. Ther. 284: 734-738, 1993.
    • (1993) J. Pharmacol. Exp. Ther. , vol.284 , pp. 734-738
    • Bealer, S.L.1
  • 10
    • 0018097341 scopus 로고
    • Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique
    • CEDARBAUM, J. M. AND AGHAJANIAN, G. K.: Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique. J. Comp. Neurol. 178: 1-16, 1978.
    • (1978) J. Comp. Neurol. , vol.178 , pp. 1-16
    • Cedarbaum, J.M.1    Aghajanian, G.K.2
  • 11
    • 0022503862 scopus 로고
    • In vivo electrophysiological evidence for the regulatory role of autoreceptors on serotoninergic terminals
    • CHAPUT, Y., BLIER, P. AND DE MONTIGNY, C.: In vivo electrophysiological evidence for the regulatory role of autoreceptors on serotoninergic terminals. J. Neurosci. 6: 2796-2801, 1986.
    • (1986) J. Neurosci. , vol.6 , pp. 2796-2801
    • Chaput, Y.1    Blier, P.2    De Montigny, C.3
  • 12
    • 0023727002 scopus 로고
    • 1 receptor antagonist BMY 7378 on the 5-HT neurotransmission: Electrophysiological studies in the rat central nervous system
    • 1 receptor antagonist BMY 7378 on the 5-HT neurotransmission: Electrophysiological studies in the rat central nervous system. J. Pharmacol. Exp. Ther. 246: 359-370, 1988.
    • (1988) J. Pharmacol. Exp. Ther. , vol.246 , pp. 359-370
    • Chaput, Y.1    De Montigny, C.2
  • 13
    • 0027335524 scopus 로고
    • 2 agonist augments γ-aminobutyric acid and excitatory amino acid inputs to noradrenergic locus coeruleus neurons
    • 2 agonist augments γ-aminobutyric acid and excitatory amino acid inputs to noradrenergic locus coeruleus neurons. Neuroscience 54: 409-420, 1993.
    • (1993) Neuroscience , vol.54 , pp. 409-420
    • Chiang, C.1    Aston-Jones, G.2
  • 14
    • 0029070521 scopus 로고
    • A double-blind, placebo-controlled study of ORG 3770 in depressed outpatients
    • CLAGHORN, J. L. AND LESEM, M. D.: A double-blind, placebo-controlled study of ORG 3770 in depressed outpatients. J. Affect. Disord. 34: 165-172, 1995.
    • (1995) J. Affect. Disord. , vol.34 , pp. 165-172
    • Claghorn, J.L.1    Lesem, M.D.2
  • 15
    • 0026684148 scopus 로고
    • The effect of adrenergic drugs on serotonin metabolism in the nucleus raphe dorsalis of the rat, studied by in vivo voltammetry
    • CLEMENT, H.-W., GEMSA, D. AND WESEMAN, W.: The effect of adrenergic drugs on serotonin metabolism in the nucleus raphe dorsalis of the rat, studied by in vivo voltammetry. Eur. J. Pharmacol. 217: 43-48, 1992.
    • (1992) Eur. J. Pharmacol. , vol.217 , pp. 43-48
    • Clement, H.-W.1    Gemsa, D.2    Weseman, W.3
  • 17
    • 0023754346 scopus 로고
    • Electrophysiological characterization of adrenoceptors in the rat dorsal hippocampus. I. Receptors mediating the effect of microiontophoreticaliy applied norepinephrine
    • CURET, O. AND DE MONTIGNY, C.: Electrophysiological characterization of adrenoceptors in the rat dorsal hippocampus. I. Receptors mediating the effect of microiontophoreticaliy applied norepinephrine. Brain Res. 475: 35-46, 1988a.
    • (1988) Brain Res. , vol.475 , pp. 35-46
    • Curet, O.1    De Montigny, C.2
  • 18
    • 0023708464 scopus 로고
    • Electrophysiological characterization of adrenoceptors in the rat dorsal hippocampus. II. Receptors mediating the effect of synaptically-released norepinephrine
    • CURET, O. AND DE MONTIGNY, C.: Electrophysiological characterization of adrenoceptors in the rat dorsal hippocampus. II. Receptors mediating the effect of synaptically-released norepinephrine. Brain Res. 475: 47-57, 1988b.
    • (1988) Brain Res. , vol.475 , pp. 47-57
    • Curet, O.1    De Montigny, C.2
  • 19
    • 0026011459 scopus 로고
    • Acute and chronic effect of the atypical antidepressant mianserin on brain noradrenergic neurons
    • CURTIS, A. L. AND VALENTINO, R. J.: Acute and chronic effect of the atypical antidepressant mianserin on brain noradrenergic neurons. Psychopharmacology 103: 330-338, 1991.
    • (1991) Psychopharmacology , vol.103 , pp. 330-338
    • Curtis, A.L.1    Valentino, R.J.2
  • 20
    • 0023929271 scopus 로고
    • Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, org 3770 and its enantiomers
    • DE BOER, T., MAURA, G., RAITERI, M., DE VOS, C. J., WIERINGA, J. AND PINDER, R. M.: Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, org 3770 and its enantiomers. Neuropharmacology 27: 399-408, 1988.
    • (1988) Neuropharmacology , vol.27 , pp. 399-408
    • De Boer, T.1    Maura, G.2    Raiteri, M.3    De Vos, C.J.4    Wieringa, J.5    Pinder, R.M.6
  • 22
    • 0023630323 scopus 로고
    • 2 receptors throughout the central nervous system using quantitative autoradiography
    • 2 receptors throughout the central nervous system using quantitative autoradiography. Brain Res. 421: 263-279, 1987.
    • (1987) Brain Res. , vol.421 , pp. 263-279
    • Fischette, C.T.1    Nock, B.2    Renner, K.3
  • 24
    • 0011229911 scopus 로고
    • Effects of metergoline on central monoamine neurons. Evidence for a selective blockade of central 5-HT receptors
    • FUXE, K., AGNATI, L. AND EVERITT, B.: Effects of metergoline on central monoamine neurons. Evidence for a selective blockade of central 5-HT receptors. Neurosci. Lett. 1: 283-290, 1975.
    • (1975) Neurosci. Lett. , vol.1 , pp. 283-290
    • Fuxe, K.1    Agnati, L.2    Everitt, B.3
  • 25
    • 0026011052 scopus 로고
    • Effects of idazoxan on dorsal raphe 5-hydroxytryptamine neuronal function
    • GARRAT, J. C., CRESPI, F., MASON, R. AND MARSDEN, C. A.: Effects of idazoxan on dorsal raphe 5-hydroxytryptamine neuronal function. Eur. J. Pharmacol. 193: 87-93, 1991.
    • (1991) Eur. J. Pharmacol. , vol.193 , pp. 87-93
    • Garrat, J.C.1    Crespi, F.2    Mason, R.3    Marsden, C.A.4
  • 26
    • 0029066921 scopus 로고
    • 3 agonist 2-methyl-5-HT on the 5-HT system on the rat brain
    • 3 agonist 2-methyl-5-HT on the 5-HT system on the rat brain. Synapse 20: 54-67, 1995.
    • (1995) Synapse , vol.20 , pp. 54-67
    • Haddjeri, N.1    Blier, P.2
  • 27
    • 0028294464 scopus 로고
    • Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from dorsal raphe nucleus
    • HENSLER, J. G., FERRY, R. C., LABOW, D. M., KOVASHICH, G. B. AND FRAZER, A.: Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from dorsal raphe nucleus. Synapse 17: 1-15, 1994.
    • (1994) Synapse , vol.17 , pp. 1-15
    • Hensler, J.G.1    Ferry, R.C.2    Labow, D.M.3    Kovashich, G.B.4    Frazer, A.5
  • 29
    • 0022407042 scopus 로고
    • The efferent projections from reticular formation and locus coeruleus studied by anterograde and retrograde axonal transport in the rat
    • JONES, B E. AND YANG, T.-Z.: The efferent projections from reticular formation and locus coeruleus studied by anterograde and retrograde axonal transport in the rat. J. Comp. Neurol. 242: 56-92, 1985.
    • (1985) J. Comp. Neurol. , vol.242 , pp. 56-92
    • Jones, B.E.1    Yang, T.-Z.2
  • 30
    • 0001192938 scopus 로고
    • Electrophysiology of hippocampal neurons. II. After potentials and repetitive firing
    • KANDEL, E. R. AND SPENCER, W. A.: Electrophysiology of hippocampal neurons. II. After potentials and repetitive firing. J. Neurophysiol. 24: 243-259, 1961.
    • (1961) J. Neurophysiol. , vol.24 , pp. 243-259
    • Kandel, E.R.1    Spencer, W.A.2
  • 31
    • 0025886658 scopus 로고
    • Effects of repeated treatment with 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on the autoregulatory control of dorsal raphe 5-HT neuronal firing and cortical 5-HT release
    • KIDD, E. J., GARRAT, J. C. AND MARSDEN, C. A.: Effects of repeated treatment with 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on the autoregulatory control of dorsal raphe 5-HT neuronal firing and cortical 5-HT release. Eur. J. Pharmacol. 200: 131-139, 1991.
    • (1991) Eur. J. Pharmacol. , vol.200 , pp. 131-139
    • Kidd, E.J.1    Garrat, J.C.2    Marsden, C.A.3
  • 32
    • 0021950526 scopus 로고
    • Effects of ketanserin on responses to serotonin in the prefrontal cortex, lateral geniculate and dorsal raphe nucleus
    • LAKOSKI, J. N. AND AGHAJANIAN, G. K.: Effects of ketanserin on responses to serotonin in the prefrontal cortex, lateral geniculate and dorsal raphe nucleus. Neuropharmacology 24: 265-273, 1985.
    • (1985) Neuropharmacology , vol.24 , pp. 265-273
    • Lakoski, J.N.1    Aghajanian, G.K.2
  • 33
    • 0018134765 scopus 로고
    • Serotonin nerve terminals in the locus coeruleus of the adult rat: A radioaoutographic study
    • LÉGER, L. AND DESCARRIES, L.: Serotonin nerve terminals in the locus coeruleus of the adult rat: A radioaoutographic study. Brain Res. 145: 1-13, 1978.
    • (1978) Brain Res. , vol.145 , pp. 1-13
    • Léger, L.1    Descarries, L.2
  • 34
    • 0014591658 scopus 로고
    • Projections of the nucleus locus coeruleus in the albino rat
    • LOIZOU, L. A.: Projections of the nucleus locus coeruleus in the albino rat. Brain Res. 15: 563-569, 1969.
    • (1969) Brain Res. , vol.15 , pp. 563-569
    • Loizou, L.A.1
  • 35
    • 0028983146 scopus 로고
    • Afferent projections to rat locus coeruleus demonstrated by retrograde and anterograde tracing with cholera-toxin B subunit and Phaseolus vulgaris leucoagglutinin
    • LUPPI, P.-H., ASTON-JONES, G., AKAOKA, H., CHOUVET, G. AND JOUVET, M.: Afferent projections to rat locus coeruleus demonstrated by retrograde and anterograde tracing with cholera-toxin B subunit and Phaseolus vulgaris leucoagglutinin. Neuroscience 65: 119-160, 1995.
    • (1995) Neuroscience , vol.65 , pp. 119-160
    • Luppi, P.-H.1    Aston-Jones, G.2    Akaoka, H.3    Chouvet, G.4    Jouvet, M.5
  • 36
    • 0026019121 scopus 로고
    • Monoaminergic interaction in the central nervous system: A morphological analysis in the locus coeruleus of the rat
    • MAEDA, T., KOJIMA, Y., ARAI, R., FUJIMIYA, M., KIMURA, H., KITAHAMA, K. AND GEFFARD, M.: Monoaminergic interaction in the central nervous system: A morphological analysis in the locus coeruleus of the rat. Comp. Biochem. Physiol. 98C: 193-202, 1991.
    • (1991) Comp. Biochem. Physiol. , vol.98 C , pp. 193-202
    • Maeda, T.1    Kojima, Y.2    Arai, R.3    Fujimiya, M.4    Kimura, H.5    Kitahama, K.6    Geffard, M.7
  • 37
    • 0019971988 scopus 로고
    • Relative potencies of alpha-1 and alpha-2 antagonists in the locus ceruleus, dorsal raphe and lateral geniculate nuclei: An electrophysiological study
    • MARWAHA, J. AND AGHAJANIAN, G. K.: Relative potencies of alpha-1 and alpha-2 antagonists in the locus ceruleus, dorsal raphe and lateral geniculate nuclei: An electrophysiological study. J. Pharmacol. Exp. Ther. 222: 287-293, 1982.
    • (1982) J. Pharmacol. Exp. Ther. , vol.222 , pp. 287-293
    • Marwaha, J.1    Aghajanian, G.K.2
  • 41
    • 0017734161 scopus 로고
    • A serotonergic innervation of noradrenergic neurons in nucleus locus coeruleus: Demonstration by immunocytochemical localization of transmitter specific enzymes tyrosine hydroxylase
    • PICKEL, V. M., JOH, T. H. AND REIS, D. J.: A serotonergic innervation of noradrenergic neurons in nucleus locus coeruleus: Demonstration by immunocytochemical localization of transmitter specific enzymes tyrosine hydroxylase. Brain Res. 131: 197-214, 1977.
    • (1977) Brain Res. , vol.131 , pp. 197-214
    • Pickel, V.M.1    Joh, T.H.2    Reis, D.J.3
  • 42
    • 0027399143 scopus 로고
    • Third-generation antidepressant
    • PINDER, R. M. AND WIERINGA J. H.: Third-generation antidepressant. Med. Res. Rev. 13: 259-325, 1993.
    • (1993) Med. Res. Rev. , vol.13 , pp. 259-325
    • Pinder, R.M.1    Wieringa, J.H.2
  • 43
    • 0001797297 scopus 로고
    • Behavioral correlates and firing repertoires of neurons in the dorsal hippocampal formation and septum of unrestrained rats
    • ed. by R. L. Isaacson and K. H. Pribram, Plenum Press, New York
    • RANCK, J. B.: Behavioral correlates and firing repertoires of neurons in the dorsal hippocampal formation and septum of unrestrained rats. In The Hippocampus, ed. by R. L. Isaacson and K. H. Pribram, pp, 207-244, Plenum Press, New York, 1975.
    • (1975) The Hippocampus , pp. 207-244
    • Ranck, J.B.1
  • 46
    • 0018333431 scopus 로고
    • Serotonergic innervation of the locus coeruleus from the dorsal raphe and its action on the responses to noxious stimuli
    • Lond.
    • SEGAL, M.: Serotonergic innervation of the locus coeruleus from the dorsal raphe and its action on the responses to noxious stimuli. J. Physiol. (Lond.) 286: 401-415, 1979.
    • (1979) J. Physiol. , vol.286 , pp. 401-415
    • Segal, M.1
  • 47
    • 0024591462 scopus 로고
    • The effects of chronic treatment with amitriptyline and MDL 72394 on the control of 5-HT release in vivo
    • SLEIGHT, A. J., SMITH, R. J., MARSDEN, C. A. AND PALFREYMAN, M. G.: The effects of chronic treatment with amitriptyline and MDL 72394 on the control of 5-HT release in vivo. Neuropharmacology 28: 477-180, 1989.
    • (1989) Neuropharmacology , vol.28 , pp. 477-1180
    • Sleight, A.J.1    Smith, R.J.2    Marsden, C.A.3    Palfreyman, M.G.4
  • 48
    • 0025082572 scopus 로고
    • Mirtazapine vs. amitriptyline vs. placebo in the treatment of major depressive disorder
    • SMITH, W. T., GLAUDIN, V., PANAGIDES, J. AND GILVARY, E.: Mirtazapine vs. amitriptyline vs. placebo in the treatment of major depressive disorder. Psychopharmacol. Bull. 26: 191-196, 1990.
    • (1990) Psychopharmacol. Bull. , vol.26 , pp. 191-196
    • Smith, W.T.1    Glaudin, V.2    Panagides, J.3    Gilvary, E.4
  • 49
    • 0016593641 scopus 로고
    • Inhibition of both NA and 5-HT neurons in brain by the α-adrenergic agonist clonidine
    • SVENSSON, T. H., BUNNEY, B. S. AND AGHAJANIAN, G. K.: Inhibition of both NA and 5-HT neurons in brain by the α-adrenergic agonist clonidine. Brain Res. 92: 291-306, 1975.
    • (1975) Brain Res. , vol.92 , pp. 291-306
    • Svensson, T.H.1    Bunney, B.S.2    Aghajanian, G.K.3
  • 52
    • 0028078570 scopus 로고
    • Projections of the dorsal raphe nucleus to brainstem: PHA-L analysis in the rat
    • VERTES, R. P. AND KOCSIS, B.: Projections of the dorsal raphe nucleus to brainstem: PHA-L analysis in the rat. J. Comp. Neurol. 340: 11-26, 1994.
    • (1994) J. Comp. Neurol. , vol.340 , pp. 11-26
    • Vertes, R.P.1    Kocsis, B.2
  • 54
    • 0019224027 scopus 로고
    • 2 receptors: Light microscopic autoradiographic localization
    • 2 receptors: Light microscopic autoradiographic localization. Proc. Natl. Acad. Sci. U.S.A. 77: 1696-1700, 1980.
    • (1980) Proc. Natl. Acad. Sci. U.S.A. , vol.77 , pp. 1696-1700
    • Young, W.S.1    Kuhar, M.J.2


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