Hepatic disease and systemic lupus erythematosus: Coincidence or convergence

Systemic Lupus Erythematosus, Fourth Edition

Volumn , Issue , 2004, Pages 993-1017

  Mackay, Ian R ^a  

^a MONASH UNIVERSITY   (Australia)

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EID: 24344447044     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012433901-9/50038-7     Document Type: Chapter

References (171)

1. A.S. Cohen, W.E. Reynolds, E.C. Franklin, J.P. Kulka, M.W. Ropes, L.E. Shulman and S.L. Wallace (1971) Preliminary criteria for the classification of systemic lupus erythematosus. Bull. Rheum. Dis. 21 643-648.
2. E.M. Tan, A.S. Cohen, J.F. Fries, A.T. Masi, D.J. McShane, N.F. Rothfield, J.G. Schaller, N. Talal and R.J. Winchester (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25 1271-1277.
3. Anonymous (1999) The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes. Arthritis Rheum. 42 599-608.
4. I.R. Mackay, L.I. Taft and D.C. Cowling (1956) Lupoid hepatitis. Lancet 2 1323-1326.
5. I.R. Mackay (1994) Diagnosis of autoimmune disease: Past and present. P. Lydyard, J. Brostoff (Eds) Autoimmunity, State of the Art London: Blackwell 137-154.
6. E.M. Tan (1989) Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology. Adv. Immunol. 44 93-151.
7. L.K.F. Temple, R.S. McLeod, S. Gallinger and V.G. Wright (2001) Defining disease in the genomics era. Science 293 807-808.
8. J.G. Scadding (1996) Essentialism and nominalism in medicine: Logic of diagnosis in disease terminology. Lancet 348 594-596.
9. P.J. Johnson and I.G. McFarlane (1993) Meeting report: International Autoimmune Hepatitis Group. Hepatology 18 998-1005.
10. F. Alvarez, P.A. Berg, F.B. Bianchi, et al. (1999) International Autoimmune Hepatitis Group report: Review of criteria for diagnosis of autoimmune hepatitis. J. Hepatol. 31 929-938.
11. I.R. Mackay and B.D. Tait (1994) The history of autoimmune hepatitis. M. Nishioka, G. Toda, M. Zeniya (Eds) Autoimmune Hepatitis Amsterdam: Elsevier 3-23.
12. M.H. Barker, R.B. Capps and F.W. Allen (1945) Chronic hepatitis in the Mediterranean theatre. JAMA 129 653-659.
13. I.J. Wood, W.E. King, P.J. Parsons, J.W. Perry, M. Freeman and L. Limbrick (1948) Non-suppurative hepatitis: A study of acute and chronic forms with special reference to biochemical and histological changes. Med. J. Aust. 11 249-261.
14. J. Waldenstrom (1950) Leber, Blutproteine und Nahrungseiweiss. Dtsch. Gesellschaft Verdauungs-und Stoffwechselkrankheiten 15 113-119.
15. H.G. Kunkel, J.R. Ahrens, W.J. Eisenmenger, A.M. Bongiovanni and R.J. Slater (1951) Extreme hypergammaglobulinemia in young women with liver disease of unknown etiology [Abstract]. J. Clin. Invest. 30 654.
16. A.G. Bearn, H.G. Kunkel and R.J. Slater (1956) The problem of chronic liver disease in young women. Am. J. Med. 21 3-15.
17. R.A. Joske and W.E. King (1995) The L.E. cell phenomenon in active chronic viral hepatitis. Lancet 2 477-480.
18. I.R. Mackay and D.C. Gajdusek (1958) An “autoimmune” reaction against human tissue antigens in certain acute and chronic diseases: II. Clinical correlations. Arch. Intern. Med. 101 30-46.
19. I.R. Mackay, S. Weiden and J. Hasker (1965) Autoimmune hepatitis. Ann. N.Y. Acad. Sci. 124 767-780.
20. R.A. Bradbear, W.N. Robinson, W.G.E. Cooksley, J.W. Halliday, O.D. Harris and L.W. Powell (1984) Are the causes and presentation of chronic hepatitis changing? An analysis of 104 cases over 15 years. Q. J. Med. LIII 279-288.
21. D.R. Parker and I.G.C. Kingham (1997) Type 1 autoimmune hepatitis is primarily a disease of later life. Q. J. Med. 90 289-296.
22. H. Krook (1961) Liver cirrhosis in patients with a lupus erythematosus-like syndrome. Acta Med. Scand. 169 713-726.
23. J.J. Applebaum, H. Job and F. Kern (1961) Hepatitis associated with disseminated lupus erythematosus. Gastroenterology 40 766-771.
24. M.D. Robson (1959) Systemic lupus erythematosus complicating chronic liver disease. Guy's Hosp. Rep. 108 438-443.
25. A.E. Read, S. Sherlock and C.V. Harrison (1963) Active “juvenile” cirrhosis as part of a systemic disease and the effect of corticosteroid therapy? Gut 4 378-393.
26. P.A. Miescher, A. Braverman and E. Amorosi (1966) Progressive hypergammaglobulinaemic hepatitis. Dtsch. Med. Wschr. 91 1525-1532.
27. T.B. Reynolds, H.A. Edmondson, R.L. Peters and A. Redeker (1964) Lupoid hepatitis. Ann. Intern. Med. 61 650-666.
28. M.J. MacLachlan, G.P. Rodnan, W.M. Cooper and R.H. Fennell Jr. (1965) Chronic active (“lupoid”) hepatitis: A clinical, serological and pathological study of 20 patients. Ann. Intern. Med. 62 425-462.
29. R.D. Soloway, D.M. Summerskill, A.H. Baggenstoss and L.J. Shoenfield (1975) “Lupoid” hepatitis, a nonentity in the spectrum of chronic active liver disease. Gastroenterology 63 458-465.
30. A.J. Czaja, G.L. Davis, J. Ludwig, A.H. Baggenstoss and H.F. Taswell (1983) Autoimmune features as determinants of prognosis in steroid-treated chronic active hepatitis of uncertain etiology. Gastroenterology 85 713-717.
31. R.B. Trimble, A.S. Townes, H. Robinson, S.B. Kaplan, R.W. Chandler, A.S. Hanissian and A.T. Masi (1974) Preliminary criteria for the classification of systemic lupus erythematosus (SLE). Evaluation in early diagnosed SLE and rheumatoid arthritis. Arthritis Rheum. 17 184-188.
32. C.M. Leevy, H. Popper and S. Sherlock (1976) Diseases of the liver and biliary tract. Standardization of nomenclature, diagnostic criteria and diagnostic methodology. Fogarty International Centre Proceedings No. 22 DHEW Publication No. (NIH) 75-725 Washington, D.C.: U.S. Government Printing Office
33. I.R. Mackay (1972) The prognoses of chronic hepatitis. Ann. Intern. Med. 77 649-651.
34. J.R. Hodges, G.H. Millward-Sadler and R. Wright (1982) Chronic active hepatitis: The spectrum of disease. Lancet 1 550-552.
35. I.R. Mackay (1991) Pathogenesis of autoimmune chronic hepatitis. E.L. Krawitt, R. Wiesner (Eds) Autoimmune Liver Diseases New York: Raven 21-42.
36. International Hepatology Informatics Group (1994) Diseases of the liver and biliary tract. C.M. Leevy, S. Sherlock, N. Tygstrup, R. Zetterman (Eds) Standardisation of Nomenclature, Diagnostic Criteria and Prognosis New York: Raven
37. International Working Party (1995) Terminology of chronic hepatitis. Am. J. Gastroenterol. 90 181-189.
38. I.R. Mackay (1985) Autoimmune diseases of the liver. N.R. Rose, I.R. Mackay (Eds) The Autoimmune Disease Orlando, Florida: Academic Press 291-337.
39. A.J. Czaja (1986) Autoimmune chronic active hepatitis. A.J. Czaja, E.R. Dickson (Eds) Chronic Active Hepatitis. The Mayo Clinic Experience New York: Dekker 105-126.
40. E.L. Krawitt (1996) Autoimmune hepatitis. N. Engl. J. Med. 334 897-903.
41. R.M. Crapper, P.S. Bhathal, I.R. Mackay and I.H. Frazer (1986) “Acute” autoimmune hepatitis. Digestion 34 216-225.
42. P.L. Golding, M. Smith and R. Williams (1973) Multisystem involvement in chronic liver disease. Studies on the incidence and pathogenesis. Am. J. Med. 55 772-782.
43. M. Rizzeto, G. Swana and D. Doniach (1973) Microsomal antibodies in active chronic hepatitis and other disorders. Clin. Exp. Immunol. 15 331-344.
44. M.G.M. Smith, R. Williams, G. Walker, M. Rizzetto and D. Doniach (1974) Hepatic disorders associated with liver kidney microsomal antibodies. Br. Med. J. 2 80-84.
45. M. Rizzeto, F.B. Bianchi and D. Doniach (1974) Characterization of the microsomal antigen related to a subclass of active chronic hepatitis. Immunology 26 589-601.
46. J.C. Homberg, N. Abuaf, O. Bernard, et al. (1987) Chronic active hepatitis with antiliver/kidney microsome antibody Type 1: A second type of autoimmune hepatitis. Hepatology 7 1333-1339.
47. A.J. Czaja, H.A. Carpenter, P.J. Santrach and S.B. Moore (1995) Immunologic features and HLA associations in chronic viral hepatitis. Gastroenterology 108 157-164.
48. I.R. Mackay (1993) Towards diagnostic criteria for autoimmune hepatitis. Hepatology 18 1006-1008.
49. S. Lindgren, H.-B. Braun, G. Michel, A. Nemeth, S. Nilsson, B. Thome-Kromer and S. Ericksson (1997) Absence of LKM antibody reactivity in autoimmune and hepatitis C-related chronic liver disease in Sweden. Scand. J. Gastroenterol. 32 175-178.
50. E. Tanaka, K. Kiyosawa, T. Seki, A. Matsumoto, T. Sodeyama, S. Furuta, T. Kumagai and M. Kohara (1993) Low prevalence of hepatitis C infection in patients with autoimmune hepatitis type 1. J. Gastroenterol. Hepatol. 8 442-447.
51. G.V. Gregorio, B. Portman, F. Reid, P.T. Donaldson, D.G. Doherty, M. McCartney, A. Mowat, D. Vergani and G. Mieli-Vergani (1997) Autoimmune hepatitis in childhood: A 20 year experience. Hepatology 25 541-547.
52. I.R. Mackay (2000) Autoimmune disease overlaps and the liver: Two for the price of one? J. Gastroenterol. Hepatol. 15 3-8.
53. J. Woodward and J. Neuberger (2001) Autoimmune overlap syndromes. Hepatology 33 994-1002.
54. R.P. Kenny, A.J. Czaja, J. Ludwig and E.R. Dickson (1986) Frequency and significance of antimitochondrial antibodies in severe chronic hepatitis. Dig. Dis. Sci. 31 705-711.
55. O. Chazouillères, D. Wendiem, L. Serfaty, et al. (1998) Primary biliary cirrhosis: Autoimmune hepatitis overlap: Clinical features and response to therapy. Hepatology 28 296-301.
56. A.W. Lohse, K.-H. Meyerzum Büschenfelde, B. Franz, et al. (1999) Characterization of the overlap syndrome of primary biliary cirrhosis and autoimmune hepatitis: Evidence for it being a hepatitic form of PBC in genetically susceptible individuals. Hepatology 29 1078-1084.
57. I.R. Mackay, S. Whittingham, S. Fida, M. Myers, N. Ikuno, M.E. Gershwin and M.J. Rowley (2000) The peculiar immunity of primary biliary cirrhosis. Immunol. Rev. 174 226-237.
58. F.C. Powell, A.L. Schroeter and E.R. Dickson (1987) Primary biliary cirrhosis and the CREST syndrome: A report of 22 cases. Q. J. Med 62 75-82.
59. I.R. Mackay, M.J. Rowley and S.F. Whittingham (1993) Nuclear autoantibodies in primary biliary cirrhosis. K.-H. Meyerzum Buschenfelde, J. Hoofnagle, M. Manns (Eds) Immunology and Liver: Falk Symposium Number 70, Immunology and Liver Dordrecht: Kluwer 397-409.
60. G. Brünner and O. Klinge (1987) A cholangitis with antinuclear antibodies (immuno-cholangitis) resembling chronic destructive non-suppurative cholangitis. Dtsch. Med. Wschr. 112 1454-1458.
61. Z.D. Goodman, P.R. McNally, D.R. Davis and K.G. Ishak (1995) Autoimmune cholangitis: A variant of primary biliary cirrhosis. Clinicopathologic and serologic correlation in 200 cases. Dig. Dis. Sci. 40 1232-1242.
62. H. Kinoshita, K. Omagari, I. Matsuo, et al. (1999) Autoimmune cholangitis: Serological features in 21 Japanese cases compared with those in primary biliary cirrhosis and autoimmune hepatitis. Liver 14 122-128.
63. A.J. Czaja, H.A. Carpenter, P.J. Santrack and S.B. Moore (2000) Autoimmune cholangitis within the spectrum of autoimmune liver disease. Hepatology 31 1236-1238.
64. M. Pistina, D.J. Wallace, S. Nessim, A.L. Metzger and J.R. Klinenberg (1991) Lupus erythematosus in the 1980s: A survey of 570 patients. Semin. Arthritis Rheum. 21 55-64.
65. F. Schaffner and H. Popper (1959) Non-specific reactive hepatitis in aged and infirm people. Am. J. Dig. Dis. 4 399.
66. B.A. Runyon, D.R. LaBreque and S. Anuras (1980) The spectrum of liver disease in systemic lupus erythematosus. Am. J. Med. 69 187-194.
67. T. Gibson and A.R. Myers (1981) Subclinical liver disease in systemic lupus erythematosus. J. Rheumatol. 8 752-759.
68. M.H. Miller, M.B. Urouitz, D.D. Gladman and L.M. Blendis (1984) The liver in systemic lupus erythematosus. Q. J. Med. LIII 401-409.
69. W. Van Steenbergen, J. Beyls, J. Vermylen, J. Fevery, G. Marchal, V. Desmet and J. De Groote (1986) Lupus anticoagulant and thrombosis of the hepatic veins (Budd-Chiari syndrome). Report of three patients and review of the literature. J. Hepatol. 3 87-94.
70. B.A. Leggett (1993) The liver in systemic lupus erythematosus. J. Gastroenterol. Hepatol. 8 84-88.
71. F.P. Ruiz, J.O. Martinez, A.C.Z. Mendoza, L.R. Del Arbol and A.M. Caparros (1991) Nodular regenerative hyperplasia of the liver in rheumatic diseases: Report of seven cases and review of the literature. Semin. Arthritis Rheum. 21 47-54.
72. M. Sekiya, I. Sekigawa, T. Hishikawa, N. Iida, H. Hashimoto and S. Hirose (1997) Nodular regenerative hyperplasia of the liver in systemic lupus erythematosus. Scand. J. Rheumatol. 26 215-217.
73. J. de Groote, V.J. Desmet, P. Gedigk, et al. (1968) A classification of chronic hepatitis. Lancet 2 626-628.
74. International Group of Pathologists (1997) Acute and chronic hepatitis revisited. Lancet 2 914-919.
75. A.R. Page and R.A. Good (1960) Plasma cell hepatitis with special attention to steroid therapy. J. Dis. Child. 99 288-314.
76. H. Popper, F. Paronetto and F. Schaffner (1965) Immune processes in the pathogenesis of liver disease. Ann. N.Y. Acad. Sci. 124 781-799.
77. W.C.E. Cooksley, R.A. Bradbear, W. Robinson, H. Harrison, J.W. Halliday, L.W. Powell, H.-S. Ng, C.-S. Seah, K. Okuda, J. Scheuer and S. Sherlock (1986) The prognosis of chronic active hepatitis without cirrhosis in relation to bridging necrosis. Hepatology 6 345-348.
78. J. Searle, B.V. Harmon, C.S. Bishop and J.F.R. Kerr (1987) The significance of cell death by apoptosis in hepatobiliary disease. J. Gastroenterol. Hepatol. 2 77-96.
79. H.P. Dienes (1989) Viral and Autoimmune Hepatitis Stuttgart: Fischer Verlag 47-51.
80. I.R. Mackay, L.I. Taft and D.C. Cowling (1959) Lupoid hepatitis and the hepatic lesions of systemic lupus erythematosus. Lancet 1 65-69.
81. J.S. Beck (1961) Variations in the morphological patterns of “autoimmune” nuclear fluorescence. Lancet 1 1203-1205.
82. A.J. Czaja, M. Nishioka, S. Morshed and T. Hachiya (1994) Patterns of nuclear immunofluorescence and reactivities to recombinant nuclear antigens in autoimmune hepatitis. Gastroenterology 107 200-207.
83. A.R. Mire-Sluis, R. Gaines Das,. Lernmark, et al. (2000) The World Health Organization International Collaborative Study for islet cell antibodies. Diabetologia 43 1282-1292.
84. E.M. Tan, T.E.W. Feltkamp, J.S. Smolen, et al. (1997) Range of antinuclear antibodies in “healthy” individuals. Arthritis Rheum. 40 1601-1611.
85. I.R. Mackay (2001) Antinuclear (chromatin) autoantibodies in autoimmune hepatitis. J. Gastroenterol. Hepatol. 16 245-247.
86. J. Wesierska-Gadek and E. Penner (1996) Nuclear antigens. I.G. McFarlane, R. Williams (Eds) Molecular Basis of Autoimmune Hepatitis Austin: Landes 23-44.
87. F. Konikoff, M. Swissa and Y. Schoenfeld (1989) Autoantibodies to histones and their subfractions in chronic liver diseases. Clin. Immunol. Immunopathol. 51 77-82.
88. A.J. Czaja, C. Ming, M. Shirai and M. Nishioka (1995) Frequency and significance of antibodies to histones in autoimmune hepatitis. J. Hepatol. 23 32-38.
89. S. Jain, T. Markham and H.C. Thomas (1976) Doublestranded DNA-binding capacity of serum in acute and chronic liver disease. Clin. Exp. Immunol. 26 35-41.
90. A. Peretz, F. Mascart-Lemone, G. Nuttin and J.P. Famaey (1982) Chronic active hepatitis with a high level of anti-ds-DNA detected by a solid phase radioimmunoassay. Clin. Rheumatol. 1 208-211.
91. R. Smeenk, G. van der Lelij and T. Swaak (1982) Specificity in systemic lupus erythematosus of antibodies to double-stranded DNA measured with the polyethylene glycol precipitation assay. Arthritis Rheum. 25 631-638.
92. L.E. Gurian, T.M. Rogoff, A.J. Ware, R.E. Jordan, B. Combes and J.N. Gilliam (1985) The immunological diagnosis of chronic active “autoimmune” hepatitis: Distinction from systemic lupus erythematosus. Hepatology 5 397-402.
93. B.A. Leggett, R.V. Collins, W.G.E. Cooksley, D.I. Prentice and L.W. Powell (1987) Evaluation of the crithidia assay to distinguish between chronic active hepatitis and systemic lupus erythematosus. J. Gastroenterol. Hepatol. 2 202-211.
94. J.R. Wood, A.J. Czaja, S.J. Beaver, S.J. Hall, W.W. Ginsburg, D.K. Kaufman and H. Markowitz (1986) Frequency and significance of antibody to double-stranded DNA in chronic active hepatitis. Hepatology 6 976-980.
95. W. Emlen and L. O'Neill (1997) Clinical significance of antinuclear antibodies. Comparison of detection with immunofluorescence and enzyme-linked immunosorbent assays. Arthritis Rheum. 40 1612-1618.
96. F. Konikoff, Y. Schoenfeld, D.A. Isenberg, I. Barrison, T. Sobe, E. Theodor and H. Slor (1987) Anti-Rnp antibodies in chronic liver diseases. Clin. Exp. Rheumatol. 5 359-361.
97. E. Penner, I. Kindas-Mugge, E. Hitchman and G. Sauermann (1986) Nuclear antigens recognized by autoantibodies present in liver disease sera. Clin. Exp. Immunol. 63 428-433.
98. M. Nishioka, S.A. Morshed, S. Parveen and C. Ming (1998) Heterogeneity of antinuclear antibodies in autoimmune liver diseases. E.L. Krawitt, R.H. Wiesner, M. Nishioka (Eds) Autoimmune Liver Diseases 2nd ed. Amsterdam: Elsevier 179-216.
99. D. Kenneally, I.R. Mackay and B.H. Toh (1984) Anti-nucleolar autoantibodies demonstrated by monolayers of human fibroblasts in sera from patients with systemic lupus erythematosus, progressive systemic sclerosis and chronic active hepatitis. J. Clin. Lab. Immunol. 14 13-16.
100. J. Wesierska-Gadek, E. Penner, E. Hitchman and G. Sauermann (1988) Antibodies to nuclear lamins in autoimmune liver disease. Clin. Immunol. Immunopathol. 49 107-115.
101. M.J. Smalley, I.R. Mackay and S. Whittingham (1968) Antinuclear factors and human leucocytes: Reaction with granulocytes and lymphocytes. Aust. Ann. Med. 17 28-32.
102. D. Zauli, S. Ghetti, A. Grassi, C. Descovich, F. Cassam, G. Ballardini, L. Muratori and F.B. Bianchi (1997) Neutrophil cytoplasmic antibodies in type 1 and type 2 autoimmune hepatitis. Hepatology 25 1005-1007.
103. P.E. Spronk, H. Bootsma, G. Horst, M.G. Huitema, P.C. Limburg, J.W. Cohen Tervaert and C.G. Kallenberg (1996) Antineutrophilcytoplasmic antibodies in systemic lupus erythematosus. Br. J. Rheumatol. 35 625-631.
104. I.R. Mackay and B.-H. Toh (2002) Autoimmune hepatitis. The way we were, the way we are today, and the way we hope to be. Autoimmunity 35 293-305.
105. P.A. Berg, E. Stechemesser, J. Strienz, et al. (1981) Hypergam maglobulinämische chronisch aktive Hepatitis mit Nachweis von leber-pankreas-spezifischen komplemtbindenden Autoantiköpern. Verh. Dtsch. Ges. Inn. Med. 87 921-927.
106. M. Manns, G. Gerken, A. Kyriatsoulis, et al. (1987) Characterization of a new subgroup of autoimmune chronic active hepatitis by autoantibodies against a soluble liver antigen. Lancet 1 292-294.
107. B. Wächter, A. Kyriatsoulis, A.W. Lohse, G. Gerken, K.-H. Meyer Zum Büschenfelde and M.P. Manns (1990) Characterisation of liver cytokeratin as a major target antigen of anti-SLA antibodies. J. Hepatol. 11 232-239.
108. J. Wesierska-Gadek, R. Grimm, E. Hitchmann and E. Penner (1998) Members of the glutathione S-transferase gene family are antigens in autoimmune hepatitis. Gastroenterology 114 329-335.
109. I. Wies, S. Brunner, J. Henninger, et al. (2000) Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis. Lancet 355 1510-1515.
110. M. Costa, J.L. Rodriguez-Sanchez, A.J. Czaja and C. Gelpi (2000) Isolation and characterization of cDNA encoding the antigenic protein of the human tRNP (ser) sec complex recognized by autoantibodies from patients with type-1 autoimmune hepatitis. Clin. Exp. Immunol. 121 364-374.
111. T. Kevenbeck, A.W. Lohse and J.A. Grötzinger (2001) A coinformational approach suggests the function of the autoimmune hepatitis target antigen soluble liver antigen/liver pancreas. Hepatology 34 230-233.
112. K. Elkon, S. Skelly, A. Parnassa, A.P. Moller, W. Danho, H. Weissbach and N. Brot (1986) Identification and chemical synthesis of a ribosomal protein antigenic determinant in systemic lupus erythematosus. Proc. Natl. Acad. Sci. U.S.A. 83 7419-7423.
113. E. Koren, W. Schnitz and M. Reichlin (1993) Concomitant development of chronic active hepatitis and antibodies to ribosomal P proteins in a patient with systemic lupus erythematosus. Arthritis Rheum. 36 1325-1328.
114. E. Koren, M.W. Reichlin, M. Koscec, R.D. Fugate and M. Reichlin (1992) Autoantibodies to the ribosomal P proteins react with a plasma membrane related target on human cells. J. Clin. Invest. 89 1236-1241.
115. M. Koscec, E. Koren, M. Wolfson-Reichlin, R.D. Fugate, E. Trieu, I.N. Targoff and M. Reichlin (1997) Autoantibodies to ribosomal P proteins penetrate into live hepatocytes and cause cellular dysfunction in culture. J. Immunol. 159 2033-2041.
116. J.B. Winfield (1997) Are anti-ribosomal P protein antibodies a type of anti-lymphocyte antibody? Clin. Exp. Immunol. 109 1-3.
117. F.C. Arnett and M. Reichlin (1995) Lupus hepatitis: An under-recognized feature associated with autoantibodies to ribosomal P. Am. J. Med. 99 465-472.
118. M. Hulsey, R. Coldstein, L. Scully, W. Surbeck and M. Reichlin (1995) Anti-ribosomal P antibodies in systemic lupus erythematosus: A case control study correlating hepatic and renal disease. Clin. Immunol. Immunopathol. 74 252-256.
119. I.G. McFarlane, B.M. McFarlane, G.N. Major, P. Tolley and R. Williams (1984) Identification of the hepatic asialoglycoprotein receptor (hepatic lectin) as a component of liver specific membrane lipoprotein (LSP). Clin. Exp. Immunol. 55 347-354.
120. B. McFarlane (1996) Hepatocellular membrane antigens. I.G. McFarlane, R. Williams (Eds) Molecular Basis of Autoimmune Hepatitis Austin: Landes 75-104.
121. U. Treichel, B. McFarlane, T. Seki, et al. (1994) Demographics of anti-asialoglycoprotein receptor autoantibodies in autoimmune hepatitis. Gastroenterology 107 799-804.
122. P. Kurki (1994) Cytoskeleton antibodies. M. Nishioka, G. Toda, M. Zeniya (Eds) Autoimmune Hepatitis Amsterdam: Elsevier 185-198.
123. B.-H. Toh (1979) Smooth muscle autoantibodies and autoantigens. Clin. Exp. Immunol. 38 621-628.
124. S. Whittingham, J. Irwin, I.R. Mackay and M. Smalley (1996) Smooth muscle autoantibody in “autoimmune” hepatitis. Gastroenterology 51 499-505.
125. S.F. Whittingham and I.R. Mackay (1996) Smooth muscle autoantibodies. J.B. Peter, Y. Schoenfeld (Eds) Autoantibodies Amsterdam: Elsevier 767-773.
126. M. Fusconi, F. Cassani, M. Lenzi, G. Ballardini, U. Volta and F.B. Bianchi (1990) Anti-actin antibodies: A new test for an old problem. J. Immunol. Methods 130 1-8.
127. E.L.R. Cançado, L. Vilas-Boas, C.P. Abrantes-Lemos, N.F. Novo, G. Porta, L.C. Da Silva and A.A. Laudanna (1996) Heat serum inactivation as a mandatory procedure for anti-actin antibody detection in cell culture. Hepatology 23 1098-1104.
128. E.L.R. Cançado, C.P. Abrantes-Lemos, L.S. Vilas-Boas, N.F. Novo, F.J. Carrilho and A.A. Laudanna (2001) Thermolabile and calcium-dependent serum factor interferes with polymerized actin, and impairs anti-actin antibody detection. J. Autoimmun. 17 223-228.
129. A.J. Czaja, F. Cassani, M. Cataleta, P. Valentine and F.B. Bianchi (1996) Frequency and significance of antibodies to actin in type 1 autoimmune hepatitis. Hepatology 24 1068-1073.
130. R.A. Silvestrini and E.M. Benson (2001) Whither smooth muscle antibodies in the third millenium. J. Clin. Pathol. 54 677-678.
131. S. Yasuura, T. Veno, S. Watanabe, M. Hirose and T. Namahisa (1989) Immunocytochemical localization of myosin in normal and phalloidin-treated rat hepatocytes. Gastroenterology 97 982-989.
132. I.R. Mackay (1999) Immunological perspectives on chronic hepatitis: Virus infection, autoimmunity and xenobiotics. Hepatogastroenterology 46 3021-3033.
133. D.J. Waxman, D.P. Lapenson, M. Krishnan, O. Bernard, G. Kreibich and F. Alvarez (1988) Antibodies to liver/kidney microsomes in chronic active hepatitis recognized specific forms of hepatic cytochrome P450. Gastroenterology 95 1326-1331.
134. M.P. Manns, E.F. Johnson, K.J. Griffin, E.M. Tan and K.F. Sullivan (1989) Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis in cytochrome P450db. J. Clin. Invest. 83 1066-1072.
135. M.P. Manns, K.J. Griffin, K.F. Sullivan and E.F. Johnson (1991) LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P450 monooxygenase. J. Clin. Invest. 88 1370-1378.
136. J.-C. Homberg, C. André and N. Abuaf (1984) A new anti-liver/kidney microsome antibody (anti-LKM2) in tienilic induced hepatitis. Clin. Exp. Immunol. 55 561-570.
137. P.H. Beaune, P.M. Dansette, D. Mansuy, L. Kiffel, M. Finck, C. Amar, J.P. Leroux and J.-C. Homberg (1987) Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis directed against a human liver cytochrome P450 that hydroxylates the drug. Proc. Natl. Acad. Sci. U.S.A. 84 551-555.
138. M. Bourdi, D. Larrey, J. Nataf, J. Bernuau, D. Pessayre, M. Iwasaki, P. Guengerich and P.H. Beaune (1990) Anti-liver endoplasmatic reticulum auto-antibodies are directed against human cytochrome P450 IA2: A specific marker of dihydralazine-induced hepatitis. J. Clin. Invest. 85 1967-1973.
139. M.P. Manns and P. Obermayer-Straub (1997) Cytochromes P450 and UDP-glucuronyl transferases: Model antigens to study drug-induced, virus-induced and autoimmune liver diseases. Hepatology 26 1054-1066.
140. O. Crivelli, C. Lavarini, E.A. Chiaberge, A. Amoroso, P. Farci, F. Negro and M. Rizzetto (1983) Microsomal auto-antibodies in chronic infection with the HBsAg associated delta(δ) agent. Clin. Exp. Immunol. 54 232-238.
141. M. Durazzo, T. Philipp, F.N.A.M. van Pelt, B. Lüttig, E. Borghesio, G. Michel, E. Schmidt, S. Loges, M. Rizzetto and M. Manns (1995) Heterogeneity of microsomal auto-antibodies (LKM) in chronic hepatitis C and D virus infection. Gastroenterology 108 455-462.
142. C.P. Strassburg, P. Obermayer-Straub, B. Alex, M. Durazzo, M. Rizzetto, R.H. Tukey and M.P. Manns (1996) Autoantibodies against glucuronosyltransferases differ between viral hepatitis and autoimmune hepatitis. Gastroenterology 111 1582-1592.
143. T. Bachrich, T. Thalhammer, W. Jäger, P. Haslmayer, B. Alihodzic, S. Bakos, E. Hitchman, A.M. Senderowicz and E. Penner (2001) Characterization of auto-antibodies against uridine-diphosphate glucuronosyltransferase in patients with inflammatory liver diseases. Hepatology 33 1053-1059.
144. E. Martin, N. Abauf, F. Cavalli, V. Durand, C. Johanet and J.-C. Homberg (1988) Antibody to liver cytosol (anti-LC1) in patients with autoimmune chronic active hepatitis type 2. Hepatology 8 1662-1666.
145. N. Abauf, C. Johanet, P. Chretien, E. Martini, E. Soulier, S. Laperche and J.-C. Homberg (1992) Characterization of the liver cytosol antigen type 1 reacting with autoantibodies in chronic active hepatitis. Hepatology 16 892-898.
146. S. Han, M. Tredger, G.V. Gregorio, G. Mieli-Vergani and D. Vergani (1995) Anti-liver cytosolic antigen type 1 (LC1) antibodies in childhood autoimmune liver disease. Hepatology 21 58-62.
147. L. Muratori, M. Cataleta, P. Muratori, P. Manotti, M. Lenzi, F. Cassani and F.B. Bianchi (1995) Detection of anti-liver cytosol antibody type 1 (anti-LC1) by immunodiffusion, counterimmunoelectrophoresis and immunoblotting: Comparison of different techniques. J. Immunol. Methods. 187 259-264.
148. P. Lapierre, O. Hajoui, J.-C. Homberg and F. Alvarez (1999) Formaminotransferase cyclodeaminase is an organ-specific autoantigen recognised by sera of patients with autoimmune hepatitis. Gastroenterology 116 643-649.
149. L. Muratori, E. Sztul, M. P. Muratori, Y.-S. Gao, A. Ripalti, C. Ponte, M. Lenzi, M.P. Landini and F.B. Bianchi (2001) Distinct epitopes on formaminotransferase cyclodeminase induce liver cytosol antibody type 1. Hepatology 34 494-501.
150. R.W. McMurray and K. Elbourne (1997) Hepatitis C virus infection and autoimmunity. Semin. Arthritis Rheum. 26 689-701.
151. F. Lunel, N. Abauf, L. Frangeul, et al. (1992) Liver/kidney microsome antibody type 1 and hepatitis C virus infection. Hepatology 16 630-636.
152. K. Choudhuri, G. Miele-Vergani and D. Vergani (1997) Cytochrome P4502D6: Understanding an autoantigen. Clin. Exp. Immunol. 108 381-383.
153. B.D. Clifford, D. Donahue, L. Sonith, E. Cable, B. Lüttig, M. Manns and H.L. Bonkovsky (1995) Prevalence of serological markers of autoimmunity in patients with hepatitis C. Hepatology 21 613-619.
154. A.R. Kammer, S.H. Van der Burg, B. Grabscheid, I.P. Hunziger, K.M. Kwappenberg, J. Reichen, C.J. Meleif and A. Cerny (1999) Molecular mimicry of human cytochrome P450 by hepatitis C virus at the level of cytotoxic T cell recognition. J. Exp. Med. 190 169-176.
155. E.K. Wakeland, K. Liu, R.R. Graham and T.W. Behrens (2001) Delineating the genetic basis of systemic lupus erythematosus. Immunity 15 397-408.
156. I.R. Mackay and P.J. Morris (1972) Association of autoimmune chronic hepatitis with HLA-A1-B8. Lancet 2 793-795.
157. I.R. Mackey and B.D. Tait (1980) HLA associations with autoimmune-type chronic active hepatitis: Identification of B8-DRw3 haplotype by family studies. Gastroenterology 79 95-98.
158. I.R. Mackay, R.M. O'Brien, S. Whittingham and B.D. Tait (1991) Autoimmune hepatitis and other diseases of the liver: Immunogenetic aspects. N. Farid (Eds) The Immunogenetics of Autoimmune Disease Volume 2 Boca Raton Florida: CRC Press 119-213.
159. B. Tait, I.R. Mackay, P.H. Board, M. Coggan, P. Emery and G. Eckardt (1989) HLA A1, B8, DR3 extended haplotypes in autoimmune chronic hepatitis. Gastroenterology 97 479-481.
160. D.G. Doherty, J.A. Underhill, P.T. Donaldson, K. Manabe, G. Mieli-Vergani, A.L.F.W. Eddleston, D. Vergani, A.G. Demaine and R. Williams (1994) Polymorphism in the human complement C4 genes and genetic susceptibility to autoimmune hepatitis. Autoimmunity 18 243-249.
161. P.T. Donaldson, D.G. Doherty, K.M. Hayllar, I.G. McFarlane, P.J. Johnson and R. Williams (1991) Susceptibility to autoimmune chronic active hepatitis: Human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors. Hepatology 13 701-706.
162. A.J. Czaja, M.D. Strettell, L.J. Thomson, P.J. Santrachi, S.B. Moore, P.T. Donaldson and R. Williams (1997) Associations between alleles of the major histocompatibility complex and type 1 autoimmune hepatitis. Hepatology 25 317-323.
163. D.G. Doherty, P.T. Donaldson, J.A. Underhill, et al. (1994) Allelic sequence variation in the HLA class II genes and proteins in patients with autoimmune hepatitis. Hepatology 19 609-615.
164. A.J. Czaja and P.T. Donaldson (2000) Genetic susceptibilities for immune expression and liver cell injury in autoimmune hepatitis. Immunol. Rev. 174 250-259.
165. Z. Fronek, L.A. Timmerman, C.A. Alper, B.H. Hahn, K. Kalunian, B.M. Peterlin and H.O. McDevitt (1990) Major histocompatibility complex genes and susceptibility to systemic lupus erythematosus. Arthritis. Rheum. 33 1542-1553.
166. T.J. Vyse, J.A. Todd and B.L. Kotzin (1998) Non-MHC genetic contributions to autoimmune disease. N.R. Rose, I.R. Mackay (Eds) The Autoimmune Diseases 3rd ed. San Diego: Academic Press 85-118.
167. G. Wick, K. Hála, H. Wolf, A. Ziemiecki, R.S. Sundick, M. Stöffler-Meilicke and M. DeBaets (1986) The role of genetically-determined primary alterations of the target organ in the development of spontaneous autoimmune thyroiditis in obese strain (OS) chickens. Immunol. Rev. 94 113-136.
168. Multiauthor Review (Co-ordinator: J. M. Davies) (2000) Molecular mimicry. Cell. Mol. Life Sci. 57 523-578.
169. S. Vento, L. Guella, F. Mirandola, F. Cainelli, G. Di Perri, M. Solbiati, T. Ferraro and E. Concia (1995) Epstein-Barr virus as a trigger for autoimmune hepatitis in susceptible individuals. Lancet 346 608-609.
170. H. Kita, I.R. Mackay, J. Van de Water and M.E. Gershwin (2001) The lymphoid liver: considerations on pathways to autoimmune injury. Gastroenterology 120 1485-14501.
171. I.R. Mackay (1996) Immune mechanisms and liver toxicity. R.G. Cameron, G. Feuer, F.A. de la Inglesia (Eds) Handbook of Experimental Pharmacology Series: Drug-Induced Hepatotoxicity Berlin: Springer