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Volumn 579, Issue 22, 2005, Pages 4978-4984

Control of p53 nuclear accumulation in stressed cells

Author keywords

DNA damage; Murine double minute 2; Nuclear export; Nuclear localization signal; p53

Indexed keywords

LEPTOMYCIN B; PROTEIN P53;

EID: 24144494193     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.08.006     Document Type: Article
Times cited : (29)

References (36)
  • 1
    • 0032931517 scopus 로고    scopus 로고
    • The p53 pathway
    • C. Prives, and P.A. Hall The p53 pathway J. Pathol. 187 1999 112 126
    • (1999) J. Pathol. , vol.187 , pp. 112-126
    • Prives, C.1    Hall, P.A.2
  • 2
    • 0034703742 scopus 로고    scopus 로고
    • P53: Death star
    • K.H. Vousden p53: death star Cell 103 2000 691 694
    • (2000) Cell , vol.103 , pp. 691-694
    • Vousden, K.H.1
  • 4
    • 0027983669 scopus 로고
    • Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
    • Y. Cho, S. Gorina, P.D. Jeffrey, and N.P. Pavletich Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations Science 265 1994 346 355
    • (1994) Science , vol.265 , pp. 346-355
    • Cho, Y.1    Gorina, S.2    Jeffrey, P.D.3    Pavletich, N.P.4
  • 5
    • 0031987277 scopus 로고    scopus 로고
    • Regulation of p53 downstream genes
    • W.S. el-Deiry Regulation of p53 downstream genes Semin. Cancer Biol. 8 1998 345 357
    • (1998) Semin. Cancer Biol. , vol.8 , pp. 345-357
    • El-Deiry, W.S.1
  • 6
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • J. Momand, G.P. Zambetti, D.C. Olson, D. George, and A.J. Levine The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation Cell 69 1992 1237 1245
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 7
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • M.H. Kubbutat, S.N. Jones, and K.H. Vousden Regulation of p53 stability by Mdm2 Nature 387 1997 299 303
    • (1997) Nature , vol.387 , pp. 299-303
    • Kubbutat, M.H.1    Jones, S.N.2    Vousden, K.H.3
  • 8
    • 0034282220 scopus 로고    scopus 로고
    • The MDM2 RING-finger domain is required to promote p53 nuclear export
    • R.K. Geyer, Z.K. Yu, and C.G. Maki The MDM2 RING-finger domain is required to promote p53 nuclear export Nat. Cell Biol. 2 2000 569 573
    • (2000) Nat. Cell Biol. , vol.2 , pp. 569-573
    • Geyer, R.K.1    Yu, Z.K.2    Maki, C.G.3
  • 9
    • 0034282102 scopus 로고    scopus 로고
    • An intact HDM2 RING-finger domain is required for nuclear exclusion of p53
    • S.D. Boyd, K.Y. Tsai, and T. Jacks An intact HDM2 RING-finger domain is required for nuclear exclusion of p53 Nat. Cell Biol. 2 2000 563 568
    • (2000) Nat. Cell Biol. , vol.2 , pp. 563-568
    • Boyd, S.D.1    Tsai, K.Y.2    Jacks, T.3
  • 10
    • 17144460505 scopus 로고    scopus 로고
    • Awakening angels
    • D. Lane Awakening angels Nature 394 1998 616 617
    • (1998) Nature , vol.394 , pp. 616-617
    • Lane, D.1
  • 11
    • 0033523015 scopus 로고    scopus 로고
    • Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2
    • C.G. Maki Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2 J. Biol. Chem. 274 1999 16531 16535
    • (1999) J. Biol. Chem. , vol.274 , pp. 16531-16535
    • Maki, C.G.1
  • 12
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • S.Y. Shieh, M. Ikeda, Y. Taya, and C. Prives DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 Cell 91 1997 325 334
    • (1997) Cell , vol.91 , pp. 325-334
    • Shieh, S.Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 13
    • 0033598754 scopus 로고    scopus 로고
    • Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage
    • N.H. Chehab, A. Malikzay, E.S. Stavridi, and T.D. Halazonetis Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage Proc. Natl. Acad. Sci. USA 96 1999 13777 13782
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 13777-13782
    • Chehab, N.H.1    Malikzay, A.2    Stavridi, E.S.3    Halazonetis, T.D.4
  • 14
    • 0033522143 scopus 로고    scopus 로고
    • DNA damage induced p53 stabilization: No indication for an involvement of p53 phosphorylation
    • C. Blattner, E. Tobiasch, M. Litfen, H.J. Rahmsdorf, and P. Herrlich DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation Oncogene 18 1999 1723 1732
    • (1999) Oncogene , vol.18 , pp. 1723-1732
    • Blattner, C.1    Tobiasch, E.2    Litfen, M.3    Rahmsdorf, H.J.4    Herrlich, P.5
  • 15
    • 0033020147 scopus 로고    scopus 로고
    • Regulation of p53 function and stability by phosphorylation
    • M. Ashcroft, M.H. Kubbutat, and K.H. Vousden Regulation of p53 function and stability by phosphorylation Mol. Cell. Biol. 19 1999 1751 1758
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1751-1758
    • Ashcroft, M.1    Kubbutat, M.H.2    Vousden, K.H.3
  • 16
    • 0035895606 scopus 로고    scopus 로고
    • Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents
    • T. Inoue, R.K. Geyer, Z.K. Yu, and C.G. Maki Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents FEBS Lett. 490 2001 196 201
    • (2001) FEBS Lett. , vol.490 , pp. 196-201
    • Inoue, T.1    Geyer, R.K.2    Yu, Z.K.3    Maki, C.G.4
  • 17
    • 0025201181 scopus 로고
    • Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis
    • G. Shaulsky, N. Goldfinger, A. Ben-Ze'ev, and V. Rotter Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis Mol. Cell. Biol. 10 1990 6565 6577
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6565-6577
    • Shaulsky, G.1    Goldfinger, N.2    Ben-Ze'Ev, A.3    Rotter, V.4
  • 18
    • 0032755396 scopus 로고    scopus 로고
    • A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain
    • S.H. Liang, and M.F. Clarke A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain J. Biol. Chem. 274 1999 32699 32703
    • (1999) J. Biol. Chem. , vol.274 , pp. 32699-32703
    • Liang, S.H.1    Clarke, M.F.2
  • 19
    • 0033559256 scopus 로고    scopus 로고
    • A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking
    • J.M. Stommel, N.D. Marchenko, G.S. Jimenez, U.M. Moll, T.J. Hope, and G.M. Wahl A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking EMBO J. 18 1999 1660 1672
    • (1999) EMBO J. , vol.18 , pp. 1660-1672
    • Stommel, J.M.1    Marchenko, N.D.2    Jimenez, G.S.3    Moll, U.M.4    Hope, T.J.5    Wahl, G.M.6
  • 20
    • 0035827335 scopus 로고    scopus 로고
    • A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation
    • Y. Zhang, and Y. Xiong A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation Science 292 2001 1910 1915
    • (2001) Science , vol.292 , pp. 1910-1915
    • Zhang, Y.1    Xiong, Y.2
  • 21
    • 0035977064 scopus 로고    scopus 로고
    • MDM2 can promote the ubiquitination, nuclear export, and degradation of p53 in the absence of direct binding
    • T. Inoue, R.K. Geyer, D. Howard, Z.K. Yu, and C.G. Maki MDM2 can promote the ubiquitination, nuclear export, and degradation of p53 in the absence of direct binding J. Biol. Chem. 276 2001 45255 45260
    • (2001) J. Biol. Chem. , vol.276 , pp. 45255-45260
    • Inoue, T.1    Geyer, R.K.2    Howard, D.3    Yu, Z.K.4    Maki, C.G.5
  • 22
    • 0034735904 scopus 로고    scopus 로고
    • MDM2-dependent ubiquitination of nuclear and cytoplasmic P53
    • Z.K. Yu, R.K. Geyer, and C.G. Maki MDM2-dependent ubiquitination of nuclear and cytoplasmic P53 Oncogene 19 2000 5892 5897
    • (2000) Oncogene , vol.19 , pp. 5892-5897
    • Yu, Z.K.1    Geyer, R.K.2    Maki, C.G.3
  • 23
    • 0028840915 scopus 로고
    • Degradation of CFTR by the ubiquitin-proteasome pathway
    • C.L. Ward, S. Omura, and R.R. Kopito Degradation of CFTR by the ubiquitin-proteasome pathway Cell 83 1995 121 127
    • (1995) Cell , vol.83 , pp. 121-127
    • Ward, C.L.1    Omura, S.2    Kopito, R.R.3
  • 24
    • 0034003005 scopus 로고    scopus 로고
    • Stress signals utilize multiple pathways to stabilize p53
    • M. Ashcroft, Y. Taya, and K.H. Vousden Stress signals utilize multiple pathways to stabilize p53 Mol. Cell. Biol. 20 2000 3224 3233
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3224-3233
    • Ashcroft, M.1    Taya, Y.2    Vousden, K.H.3
  • 26
    • 0038359369 scopus 로고    scopus 로고
    • Nitric oxide induces phosphorylation of p53 and impairs nuclear export
    • N. Schneiderhan, A. Budde, Y. Zhang, and B. Brune Nitric oxide induces phosphorylation of p53 and impairs nuclear export Oncogene 22 2003 2857 2868
    • (2003) Oncogene , vol.22 , pp. 2857-2868
    • Schneiderhan, N.1    Budde, A.2    Zhang, Y.3    Brune, B.4
  • 27
    • 0038188668 scopus 로고    scopus 로고
    • Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation
    • X. Wang, A. Zalcenstein, and M. Oren Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation Cell Death Differ. 10 2003 468 476
    • (2003) Cell Death Differ. , vol.10 , pp. 468-476
    • Wang, X.1    Zalcenstein, A.2    Oren, M.3
  • 28
    • 0032584666 scopus 로고    scopus 로고
    • Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein
    • S.H. Liang, D. Hong, and M.F. Clarke Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein J. Biol. Chem. 273 1998 19817 19821
    • (1998) J. Biol. Chem. , vol.273 , pp. 19817-19821
    • Liang, S.H.1    Hong, D.2    Clarke, M.F.3
  • 29
    • 0034642549 scopus 로고    scopus 로고
    • Nuclear exclusion of p53 in a subset of tumors requires MDM2 function
    • W. Lu, R. Pochampally, L. Chen, M. Traidej, Y. Wang, and J. Chen Nuclear exclusion of p53 in a subset of tumors requires MDM2 function Oncogene 19 2000 232 240
    • (2000) Oncogene , vol.19 , pp. 232-240
    • Lu, W.1    Pochampally, R.2    Chen, L.3    Traidej, M.4    Wang, Y.5    Chen, J.6
  • 30
    • 0034669037 scopus 로고    scopus 로고
    • Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells
    • S. Sengupta, J.L. Vonesch, C. Waltzinger, H. Zheng, and B. Wasylyk Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells EMBO J. 19 2000 6051 6064
    • (2000) EMBO J. , vol.19 , pp. 6051-6064
    • Sengupta, S.1    Vonesch, J.L.2    Waltzinger, C.3    Zheng, H.4    Wasylyk, B.5
  • 31
    • 0035883863 scopus 로고    scopus 로고
    • Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2
    • S. Sengupta, and B. Wasylyk Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2 Genes Dev. 15 2001 2367 2380
    • (2001) Genes Dev. , vol.15 , pp. 2367-2380
    • Sengupta, S.1    Wasylyk, B.2
  • 33
    • 18344377030 scopus 로고    scopus 로고
    • The p53 pathway: Positive and negative feedback loops
    • S.L. Harris, and A.J. Levine The p53 pathway: positive and negative feedback loops Oncogene 24 2005 2899 2908
    • (2005) Oncogene , vol.24 , pp. 2899-2908
    • Harris, S.L.1    Levine, A.J.2
  • 34
    • 2942744364 scopus 로고    scopus 로고
    • Efficient NES-dependent protein nuclear export requires ongoing synthesis and export of mRNAs
    • H.M. O'Hagan, and M. Ljungman Efficient NES-dependent protein nuclear export requires ongoing synthesis and export of mRNAs Exp. Cell Res. 297 2004 548 559
    • (2004) Exp. Cell Res. , vol.297 , pp. 548-559
    • O'Hagan, H.M.1    Ljungman, M.2
  • 36
    • 0037147329 scopus 로고    scopus 로고
    • P53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex
    • D.M. Keller, and H. Lu p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex J. Biol. Chem. 277 2002 50206 50213
    • (2002) J. Biol. Chem. , vol.277 , pp. 50206-50213
    • Keller, D.M.1    Lu, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.