Macrophage migration and function: From recruitment in vascular disease to redox regulation in the immune and neuroendocrine networks

Antioxidants and Redox Signaling

Volumn 7, Issue 9-10, 2005, Pages 1182-1188

  Bernhagen, Jürgen ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE;

CELL DIFFERENTIATION; EDITORIAL; HUMAN; IMMUNE SYSTEM; MACROPHAGE FUNCTION; MACROPHAGE MIGRATION; NEUROENDOCRINE SYSTEM; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; VASCULAR DISEASE;

ANIMALS; CELL MOVEMENT; CHEMOKINES; HOMEOSTASIS; HUMANS; IMMUNE SYSTEM; INFLAMMATION; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MACROPHAGES; NEUROSECRETORY SYSTEMS; OXIDATION-REDUCTION; PHAGOCYTOSIS;

EID: 24144491115     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2005.7.1182     Document Type: Editorial

References (50)

1. Alvarado C, Álvarez P, Jiménez L, and De la Fuente M. Improvement of leukocyte functions in young prematurely aging mice after a 5-week ingestion of a diet supplemented with biscuits enriched in antioxidants. Antioxid Redox Signal 7: 1203-1210, 2005.
2. Bernhagen J, Calandra T, Mitchell RA, Martin SB, Tracey KJ, Voelter W, Manogue KR, Cerami A, and Bucala R. MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia. Nature 365: 756-759, 1993.
3. Bernhagen J, Mitchell RA, Calandra T, Voelter W, Cerami A, and Bucala R. Purification, bioactivity, and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF). Biochemistry 33: 14144-14155, 1994.
4. Bernhagen J, Bacher M, Calandra T, Metz CN, Doty SB, Donnelly T, and Bucala R. An essential role for macrophage migration inhibitory factor in the tuberculin delayed-type hypersensitivity reaction. J Exp Med 183: 277-282, 1996.
5. Bertini R, Howard OMZ, Dong HF, Oppenheim JJ, Bizzarri C, Sergi R, Caselli G, Pagliei S, Romines B, Wilshire JA, Mengozzi M, Nakamura H, Yodoi J, Pekkari K, Gurunath R, Holmgren A, Herzenberg LA, Herzenberg LA, and Ghezzi P. Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant for neutrophils, monocytes, and T cells. J Exp Med 189: 1783-1789, 1999.
6. Beutler B and Rietschel ET. Innate immune sensing and its roots: the story ofendotoxin. Nat Rev Immunol 3: 169-176, 2003.
7. Bizzarri C, Holmgren A, Pekkari K, Chang G, Colotta F, Ghezzi P, and Bertini R. Requirements for the different cysteines in the chemotactic and desensitizing activity of human thioredoxin. Antioxid Redox Signal 7: 1189-1194, 2005.
8. Bloom B and Bennett B. Mechanism of a reaction in vitro associated with delayed-type hypersensitivity. Science 153: 80-82, 1966.
9. Bucala R. MIF rediscovered-cytokine, pituitary hormone, and glucocorticoid-induced regulator of the immune response. FASEB J 10: 1607-1613, 1996.
10. Bucala R. A most interesting factor. Nature 408: 167-168, 2000.
11. Burger-Kentischer A, Goebel H, Seiler R, Fraedrich G, Schaefer HE, Dimmeler S, Kleemann R, Bernhagen J, and Ihling C. Expression of macrophage migration inhibitory factor in different stages of human atherosclerosis. Circulation 105: 1561-1566, 2002.
12. Calandra T and Roger T. Macrophage migration inhibitory factor: a regulator of innate immunity. Nat Rev Immunol 3: 791-800, 2003.
13. Calandra T, Bernhagen J, Metz CN, Spiegel LA, Bacher M, Donnelly T, Cerami A, and Bucala R. MIF as a glucocorticoid-induced modulator of cytokine production. Nature 377: 68-71, 1995.
14. Cotran RS, Kumar V, and Robbins SL. Diseases of immunity. In: Robbins Pathologic Basis of Disease, 5th edit., edited by Schoen FJ. Philadelphia: W.B. Saunders Company, 1994, pp. 171-240.
15. David JR. Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. Proc Natl Acad Sci U S A 56: 72-77, 1966.
16. David JR, Al-Askari S, Lawrence HS, and Thomas L. Antigens can stimulate sensitized lymphocytes in culture to produce macrophage migration inhibitory factors. J Immunol 93: 264-273, 1964.
17. Dringen R. Oxidative and antioxidative potential of brain microglial cells. Antioxid Redox Signal 7: 1223-1233, 2005.
18. Ehrt S, Schnappinger D, Bekiranov S, Drenkow J, Shi S, Gingeras TR, Gaasterland T, Schoolnik G, and Nathan C. Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase. J Exp Med 194: 1123-1140, 2001.
19. George M and Vaughan JH. Migration of mononuclear cells in capillary tubes. Proc Soc Exp Biol Med 111: 514-521, 1962.
20. Glass CK and Witztum JL. Atherosclerosis: the road ahead. Cell 104: 503-516, 2001.
21. Gordon S. Alternative activation of macrophages. Nat Rev Immunol 3: 23-35, 2003.
22. Hamilton TA. Molecular basis of macrophage activation: from gene expression to phenotypic diversity. In: The Macrophage, vol. 2, edited by Burke B and Lewis CE. Oxford: Oxford University Press, 2002, pp. 73-102.
23. Kleemann R, Kapurniotu A, Frank RW, Gessner A, Mischke R, Flieger O, Jüttner S, Brunner H, and Bernhagen J. Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as a thiol-protein oxido-reductase. J Mol Biol 280: 85-102, 1998.
24. Kleemann R, Mischke R, Kapurniotu A, Brunner H, and Bernhagen J. Specific reduction of insulin disulfides by macrophage migration inhibitory factor (MIF) with glutathione and dihydrolipoamide: potential role in cellular redox processes. FEBS Lett 430: 191-196, 1998.
25. Kleemann R, Hausser A, Geiger G, Mischke R, Burger-Kentischer A, Flieger O, Johannes FJ, Roger T, Calandra T, Kapurniotu A, Grell M, Finkelmeier D, Brunner H, and Bernhagen J. Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1. Nature 408: 211-216, 2000.
26. Leng L, Metz CN, Fang YXJ, Donnelly S, Baugh J, Delohery T, Chen Y, Mitchell RA, and Bucala R. MIF signal transduction initiated by binding to CD74. J Exp Med 197: 1467-1476, 2003.
27. Libby P. Inflammation in atherosclerosis. Nature 420: 868-874, 2002.
28. Lue H, Kleemann R, Calandra T, Roger T, and Bernhagen J. Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease. Microbes Infect 4: 449-460, 2002.
29. Mackaness GB. The phagocytosis and inactivation of staphylococci by macrophages of normal rabbits. J Exp Med 112: 35-53, 1960.
30. Mackaness GB. The immunological basis of acquired cellular resistance. J Exp Med 120: 105-120, 1964.
31. Mackay CR. Chemokines: immunology's high impact factors. Nat Immunol 2: 95-101, 2001.
32. Mellado M, Rodriguez-Frade JM, Vila-Coro AJ, Fernandez S, Martin de Ana A, Jones DR, Toran JL, and Martinez AC. Chemokine receptor homo- or heterodimerization activates distinct signaling pathways. EMBO J 20: 2497-2507, 2001.
33. Mitchell RA and Bucala R. Tumor growth-promoting properties of macrophage migration inhibitory factor. Semin Cancer Biol 10: 359-366, 2000.
34. Mitchell RA, Liao H, Chesney J, Fingerle-Rowson G, Baugh J, David J, and Bucala R. Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: regulatory role in the innate immune response. Proc Natl Acad Sci U S A 99: 345-350, 2002.
35. Nakamura H. Thioredoxin as a key molecule in redox signaling. Antioxid Redox Signal 6: 15-17, 2004.
36. Nau GJ, Richmond JF, Schlesinger A, Jennings EG, Lander ES, and Young RA. Human macrophage activation programs induced by bacterial pathogens. Proc Natl Acad Sci U S A 99: 1503-1508, 2002.
37. Nguyen M, Lue H, Kleemann R, Thiele M, Tolle G, Finkelmeier D, Wagner E, Braun A, and Bernhagen J. The cytokine macrophage migration inhibitory factor (MIF) reduces pro-oxidative stress-induced apoptosis. J Immunol 170: 3337-3347, 2003.
38. Pekkari K and Holmgren A. Truncated thioredoxin: physiological functions and mechanism. Antioxid Redox Signal 6: 53-61, 2004.
39. Pekkari K, Gurunath R, Arner ES, and Holmgren A. Truncated thioredoxin is a mitogenic cytokine for resting human peripheral blood mononuclear cells and is present in human plasma. J Biol Chem 275: 37474-37480, 2000.
40. Roger T, David J, Glauser M, and Calandra T. MIF regulates innate immune responses through modulation of Toll-like receptor-4. Nature 414: 920-924, 2001.
41. Schober A and Weber C. Mechanisms of monocyte recruitment in vascular repair after injury. Antioxid Redox Signal 7: 1249-1257, 2005.
42. Schober A, Bernhagen J, Thiele M, Zeiffer U, Knarren S, Roller M, Bucala R, and Weber C. Stabilization of atherosclerotic plaques by blockade of macrophage migration inhibitory factor after vascular injury in apolipoprotein E-deficient mice. Circulation 109: 380-385, 2004.
43. Schrans-Stassen BHGJ, Lue H, Sonnemans DGP, Bernhagen J, and Post MJ. Stimulation of vascular smooth muscle cell migration by macrophage migration inhibitory factor. Antioxid Redox Signal 7: 1211-1216, 2005.
44. Shi S, Nathan C, Schnappinger D, Drenkow J, Fuortes M, Block E, Ding A, Gingeras TR, Schoolnik G, Akira S, Takeda K, and Ehrt S. MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis. J Exp Med 198: 987-997, 2003.
45. Thiele M and Bernhagen J. Link between macrophage migration inhibitory factor and cellular redox regulation. Antioxid Redox Signal 7: 1234-1248, 2005.
46. Verschuren L, Lindeman JHN, van Bockel JH, Abdul-Hussien H, Kooistra T, and Kleemann R. Up-regulation and coexpression of MIF and matrix metalloproteinases in human abdominal aortic aneurysms. Antioxid Redox Signal 7: 1195-1202, 2005.
47. von Knethen A and Brune B. PKCα depletion in RAW264.7 macrophages following microbial/IFNγ stimulation is PC-PLC-mediated. Antioxid Redox Signal 7: 1217-1222, 2005.
48. Waksman BH and Matoltsy M. Stimulation by tuberculin of macrophages in monolayer cultures. J Immunol 81: 220-234, 1958.
49. Weber C, Schober A, and Zernecke A. Chemokines: key regulators of mononuclear cell recruitment in atherosclerotic vascular disease. Arterioscler Thromb Vasc Biol 24: 1997-2008, 2004.
50. Weiser WY, Temple DM, Witek-Gianotti JS, Remold HG, Clark SC, and David JR. Molecular cloning of cDNA encoding a human macrophage migration inhibition factor. Proc Natl Acad Sci U S A 86: 7522-7526, 1989.