Molecular details of quinolone-DNA interactions: Solution structure of an unusually stable DNA duplex with covalently linked nalidixic acid residues and non-covalent complexes derived from it

Nucleic Acids Research

Volumn 33, Issue 15, 2005, Pages 4838-4848

  Siegmund, Karsten ^a   Maheshwary, Shruti ^b   Narayanan, Sukunath ^a   Connors, William ^b   Riedrich, Matthias ^b   Printz, Michael ^a   Richert, Clemens ^a,b  

^a UNIVERSITY OF KARLSRUHE   (Germany)

^b UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2' AMINO 2' DEOXYURIDINE; 6 FLUORO NALIDIXIC ACID; ADENINE; CINOXACIN; CYTOSINE; DEOXYURIDINE DERIVATIVE; DOUBLE STRANDED DNA; GUANINE; NALIDIXIC ACID; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG; URACIL; DNA; QUINOLONE DERIVATIVE;

ARTICLE; BASE PAIRING; COMPLEX FORMATION; CONTROLLED STUDY; COVALENT BOND; DNA SEQUENCE; DNA STRUCTURE; DRUG DNA INTERACTION; MELTING POINT; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; ULTRAVIOLET RADIATION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; NUCLEAR MAGNETIC RESONANCE; NUCLEOTIDE SEQUENCE; SOLUTION AND SOLUBILITY;

BASE SEQUENCE; DNA; MODELS, MOLECULAR; NALIDIXIC ACID; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; QUINOLONES; SOLUTIONS;

EID: 24144487083     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gki795     Document Type: Article

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