The role of lactate in brain metabolism

Neurochemistry International

Volumn 47, Issue 6, 2005, Pages 413-417

  Fillenz, Marianne ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Astrocytes; Brain; Lactate; Metabolism

Indexed keywords

GLUCOSE; GLUTAMIC ACID; LACTIC ACID;

AEROBIC METABOLISM; ASTROCYTE; BRAIN METABOLISM; CELL MEMBRANE; CORPUS STRIATUM; DENTATE GYRUS; ELECTROSTIMULATION; HIPPOCAMPUS; HUMAN; MICRODIALYSIS; NERVE CELL; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PERIKARYON; PRESYNAPTIC NERVE; PRIORITY JOURNAL; REVIEW; VISUAL STIMULATION;

EID: 24144449011     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2005.05.011     Document Type: Article

References (56)

1. A. Araque, and G. Perea Glial modulation of synaptic transmission in culture Glia 47 2004 241 248
2. A. Araque, N. Li, R.T. Doyle, and P.G. Haydon SNARE protein-dependent glutamate release from astrocytes J. Neurosci. 20 2000 666 673
3. A. Araque, E.D. Martin, G. Perea, J.I. Arellano, and W. Buno Synaptically released acetylcholine evokes Ca2+ elevations in astrocytes in hippocampal slices J. Neurosci. 22 2002 2443 2450
4. D. Attwell, and S.B. Laughlin An energy budget for signaling in the grey matter of the brain J. Cereb. Blood Flow Metab. 21 2001 1133 1145
5. D.A. Baker, Z.X. Xi, H. Shen, C.J. Swanson, and P.W. Kalivas The origin and neuronal function of in vivo nonsynaptic glutamate J. Neurosci. 22 2002 9134 9141
6. B. Barbour An evaluation of synapse independence J. Neurosci. 21 2001 7969 7984
7. +-mediated metabolic waves Proc. Natl. Acad. Sci. U.S.A. 101 2004 14937 14942
8. P. Bezzi, G. Carmignoto, L. Pasti, S. Vesce, D. Rossi, B.L. Rizzini, T. Pozzan, and A. Volterra Prostaglandins stimulate calcium-dependent glutamate release in astrocytes Nature 391 1998 281 285
9. C.S. Biggs, L.J. Fowler, P.S. Whitton, and M.S. Starr Impulse-dependent and tetrodotoxin-sensitive release of GABA in the rat's substantia nigra measured by microdialysis Brain Res. 684 1995 172 178
10. P. Bittar, Y. Charnay, L. Pellerin, C. Bouras, and P. Magistretti Selective distribution of lactate dehydrogenase isoenzymes in neurons and astrocytes of human brain J. Cereb. Blood Flow Metab. 16 1996 1079 1089
11. A.M. Brown, S. Baltan Tekkok, and B.R. Ransom Energy transfer from astrocytes to axons: the role of CNS glycogen Neurochem. Int. 45 2004 529 536
12. C.P. Chih, and E.L. Roberts Jr. Energy substrates for neurons during neural activity: a critical review of the astrocyte-neuron lactate shuttle hypothesis J. Cereb. Blood Flow Metab. 23 2003 1263 1281
13. C.P. Chih, P. Lipton, and E.L. Roberts Jr. Do active cerebral neurons really use lactate rather than glucose? Trends Neurosci. 24 2001 573 578
14. N. Cholet, L. Pellerin, E. Welker, P. Lacombe, J. Seylaz, P. Magistretti, and G. Bonvento Local injection of antisense oligonucleotides targeted to the glial glutamate transporter GLAST decreases the metabolic response to somatosensory activation J. Cereb. Blood Flow Metab. 21 2001 404 412
15. A.H. Cornell-Bell, S.M. Finkbeiner, M.S. Cooper, and J.S. Smith Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling Science 247 1990 470 473
16. M. Demestre, M. Boutelle, and M. Fillenz Stimulated release of lactate in freely moving rats is dependent on the uptake of glutamate J. Physiol. 499 1997 825 832
17. J.S. Diamond A broad view of glutamate spillover Nat. Neurosci. 5 2002 291 292
18. G.A. Dienel, and N.F. Cruz Neighborly interactions of metabolically-activated astrocytes in vivo Neurochem. Int. 43 2003 339 354
19. G.A. Dienel, and N.F. Cruz Nutrition during brain activation: does cell-to-cell lactate shuttling contribute significantly to sweet and sour food for thought? Neurochem. Int. 45 2004 321 351
20. L.K. Fellows, M.G. Boutelle, and M. Fillenz Physiological stimulation increases nonoxidative glucose metabolism in the brain of the freely moving rat J. Neurochem. 60 1993 1258 1263
21. A.E. Fray, R.J. Forsyth, M.G. Boutelle, and M. Fillenz The mechanisms controlling physiologically stimulated changes in rat brain glucose and lactate: a microdialysis study J. Physiol. 496 1996 49 57
22. R. Hepp, M. Perraut, S. Chasserot Golaz, T. Galli, D. Aunis, K. Langley, and N.J. Grant Cultured glial cells express the SNAP-25 analogue SNAP-23 Glia 27 1999 181 187
23. Y. Hu, and G.S. Wilson Rapid changes in local extracellular rat brain glucose observed with an in vivo glucose sensor J. Neurochem. 68 1997 1745 1752
24. Y. Hu, and G.S. Wilson A temporary local energy pool coupled to neuronal activity: fluctuations of extracellular lactate levels in rat brain monitored with rapid-response enzyme-based sensor J. Neurochem. 69 1997 1484 1490
25. B. Innocenti, V. Parpura, and P.G. Haydon Imaging extracellular waves of glutamate during calcium signaling in cultured astrocytes J. Neurosci. 20 2000 1800 1808
26. S.D. Jeftinija, K.V. Jeftinija, and G. Stefanovic Cultured astrocytes express proteins involved in vesicular glutamate release Brain Res. 750 1997 41 47
27. S.D. Jeftinija, K.V. Jeftinija, G. Stefanovic, and F. Liu Neuroligand-evoked calcium-dependent release of excitatory amino acids from cultured astrocytes J. Neurochem. 66 1996 676 684
28. A. Jeremic, K. Jeftinija, J. Stevanovic, A. Glavaski, and S. Jeftinija ATP stimulates calcium-dependent glutamate release from cultured astrocytes J. Neurochem. 77 2001 664 675
29. K.A. Kasischke, H.D. Vishwasrao, P.J. Fisher, W.R. Zipfel, and W.W. Webb Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis Science 305 2004 99 103
30. D. Kullmann, M. Min, F. Asztely, and D. Rusakov Extracellular glutamate diffusion determines the occupancy of glutamate receptors at CA1 synapses in the hippocampus Philos. Trans. R. Soc. Lond. B 354 1999 395 402
31. D.M. Kullmann, and F. Asztely Extrasynaptic glutamate spillover in the hippocampus: evidence and implications Trends Neurosci. 21 1998 8 14
32. D.M. Kullmann, and F. Asztely Spillover and synaptic cross talk mediated by glutamate and GABA in the mammalian brain Prog. Brain Res. 125 2000 339 351
33. S.L. Liao, and C.J. Chen l-Glutamate decreases glucose utilization by rat cortical astrocytes Neurosci. Lett. 348 2003 81 84
34. S.C. Lin, and D.E. Bergles Synaptic signaling between neurons and glia Glia 47 2004 290 298
35. S. Mangia, G. Garreffa, M. Bianciardi, F. Giove, F. Di Salle, and B. Maraviglia The aerobic brain: lactate decrease at the onset of neural activity Neuroscience 118 2003 7 10
36. M. Miele, M.G. Boutelle, and M. Fillenz The source of physiologically stimulated glutamate efflux from the striatum of conscious rats J. Physiol. 497 1996 745 751
37. M. Miele, M. Berners, M.G. Boutelle, H. Kusakabe, and M. Fillenz The determination of the extracellular concentration of brain glutamate using quantitative microdialysis Brain Res. 707 1996 131 133
38. B. Moghaddam Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to hippocampus and basal ganglia J. Neurochem. 60 1993 1650 1657
39. V. Montana, Y. Ni, V. Sunjara, X. Hua, and V. Parpura Vesicular glutamate transporter-dependent glutamate release from astrocytes J. Neurosci. 24 2004 2633 2642
40. L. Pellerin Lactate as a pivotal element in neuron-glia metabolic cooperation Neurochem. Int. 43 2003 331 338
41. L. Pellerin, and P.J. Magistretti Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization Proc. Natl. Acad. Sci. U.S.A. 91 1994 10625 10629
42. L. Pellerin, and P.J. Magistretti Food for thought: challenging the dogmas J. Cereb. Blood Flow Metab. 23 2003 1282 1286
43. L. Pellerin, G. Pellegri, P.G. Bittar, Y. Charnay, C. Bouras, J.L. Martin, N. Stella, and P.J. Magistretti Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle Dev. Neurosci. 20 1998 291 299
44. L. Peng, R.A. Swanson, and L. Hertz Effects of l-glutamate, d-aspartate, and monensin on glycolytic and oxidative glucose metabolism in mouse astrocyte cultures: further evidence that glutamate uptake is metabolically driven by oxidative metabolism Neurochem. Int. 38 2001 437 443
45. A. Peters, S.L. Palay, and H. Webster The fine structure of the nervous system: the neurons and supporting cells 1991 W.B. Saunders Philadelphia
46. R. Piet, L. Vargova, E. Sykova, D.A. Poulain, and S.H. Oliet Physiological contribution of the astrocytic environment of neurons to intersynaptic crosstalk Proc. Natl. Acad. Sci. U.S.A. 101 2004 2151 2155
47. J.T. Porter, and K.D. McCarthy Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals J. Neurosci. 16 1996 5073 5081
48. J. Ros, N. Pecinska, B. Alessandri, H. Landolt, and M. Fillenz Lactate reduces glutamate-induced neurotoxicity in rat cortex J. Neurosci. Res. 66 2001 790 794
49. D.A. Rusakov The role of perisynaptic glial sheaths in glutamate spillover and extracellular Ca(2+) depletion Biophys. J. 81 2001 1947 1959
50. E.M. Schasfoort, L.A. De Bruin, and J. Korf Mild stress stimulates rat hippocampal glucose utilization transiently via NMDA receptors, as assessed by lactography Brain Res. 475 1988 58 63
51. A. Schurr, J.J. Miller, R.S. Payne, and B.M. Rigor An increase in lactate output by brain tissue serves to meet the energy needs of glutamate-activated neurons J. Neurosci. 19 1999 34 39
52. J. Spacek Three-dimensional analysis of dendritic spines. III. Glial sheath Anat. Embryol. (Berlin) 171 1985 245 252
53. R.A. Swanson, A.C. Yu, P.H. Chan, and F.R. Sharp Glutamate increases glycogen content and reduces glucose utilization in primary astrocyte culture J. Neurochem. 54 1990 490 496
54. W. Timmerman, and B.H. Westerink Brain microdialysis of GABA and glutamate: what does it signify? Synapse 27 1997 242 261
55. A. Verkhratsky, and H. Kettenmann Calcium signalling in glial cells Trends Neurosci. 19 1996 346 352
56. A. Volterra, and C. Steinhauser Glial modulation of synaptic transmission in the hippocampus Glia 47 2004 249 257