Buspirone attenuates conditioned fear-induced c-Fos expression in the rat hippocampus

Neuroscience Letters

Volumn 389, Issue 2, 2005, Pages 115-120

  Wisłowska Stanek, Aleksandra ^a   Zienowicz, Małgorzata ^a   Lehner, Małgorzata ^b   Taracha, Ewa ^b   Bidziński, Andrzej ^b   Maciejak, Piotr ^a,b   Skórzewska, Anna ^b   Szyndler, Janusz ^a   Płaźnik, Adam ^a,b  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

Author keywords

Buspirone; c Fos protein; Contextual fear; Hippocampus; Rats

Indexed keywords

BUSPIRONE; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVERSION; CONDITIONING; CONTROLLED STUDY; DENTATE GYRUS; DOSE RESPONSE; EMOTION; EXPERIMENTAL TEST; EXPOSURE; FEAR; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; INJECTION; LABORATORY; MALE; MEMORY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; TIME; TRAINING; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY DISORDERS; AVOIDANCE LEARNING; BUSPIRONE; CONDITIONING (PSYCHOLOGY); DISEASE MODELS, ANIMAL; FEAR; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MEMORY; NEURONS; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR;

EID: 24144441710     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.07.033     Document Type: Article

References (20)

1. N.M. Barnes, and T. Sharp A review of central 5-HT receptors and their function Neuropharmacology 38 1999 1083 1152
2. C.H. Beck, and H.C. Fibiger Conditioned fear-induced changes in behavior and in the expression of the immediate early gen c-fos: with and without diazepam pretreatment J. Neurosci. 15 1995 709 720
3. M. Bialy, and L. Kaczmarek C-Fos expression as a tool to search for the neurobiological base of the sexual behavior of males Acta Neurobiol. Exp. 56 1996 567 577
4. A.W. Bruijnzeel, R. Stam, J.C. Compan, G. Croiset, L.M. Akkermans, B. Oliver, and V.M. Wiegant Long-term sensitization of Fos-responsivity in the rat central nervous system after a single stressful experience Brain Res. 819 1999 15 22
5. A. Dekeyne, M. Brocco, A. Adhumeau, A. Gobert, and M.J. Millan The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats. A comparison with other anxiolytic agents Psychopharmacology 152 2000 55 66
6. D.G. Herrera, and H.A. Robertson Activation of c-fos in the brain Prog. Neurobiol. 50 1996 83 107
7. S.P. Hunt, A. Pini, and G. Evan Induction of c-fos-like protein in spinal cord neurons following sensory stimulation Nature 326 1987 632 634
8. L. Kaczmarek C-fos in learning: beyond the mapping of neuronal activity L. Kaczmarek H.A. Robertson Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction vol. 3 2002 Elsevier Amsterdam 189 216
9. W. Kostowski, R. Stefański, and A. Płaźnik Intra-hippocampal buspirone in animal models of anxiety Eur. J. Pharmacol. 168 1989 393 396
10. A. Linden, S.J. Greene, M. Bergeron, and D.D. Schepp Anxiolytic activity of the mGLU2/3 receptor agonist LY354740 on the elevated plus maze is associated with the suppression of stress induced c-Fos in the hippocampus and increases in c-Fos induction in several other stress sensitive regions Neuropsychopharmacology 29 2004 502 513
11. P. Maciejak, E. Taracha, M. Lehner, J. Szyndler, A. Bidziński, A. Skórzewska, A. Wisłowska, M. Zienowicz, and A. Płaźnik Hippocampal mGluR1 and consolidation of contextual fear conditioning Brain Res. Bull. 62 2003 39 45
12. K. Majak, and A. Pitkanen Activation of the amygdalo-entorhinal pathway in fear-conditioning in rat Eur. J. Neurosci. 18 2003 1652 1659
13. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates second ed. 1986 Academic Press Sydney
14. A. Płaźnik, W. Kostowski, and R. Stefański Limbic mechanisms of anxiolytics acting on 5-HT receptors Pol. J. Pharmacol. 46 1994 473 477
15. P. Protais, M. Lesourd, and E. Comoy Similar pharmacological properties of 8-OH-DPAT and alnespirone (S 20499) at dopamine receptors: comparison with buspirone Eur. J. Pharmacol. 352 1998 179 187
16. H.J. Rijnders, and J.L. Slangen The discriminative stimulus properties of buspirone involve dopamine-2 receptor antagonist activity Psychopharmacology 111 1993 55 61
17. 1A receptor agonists Neuropharmacology 32 1993 977 985
18. R. Stefański, W. Pałejko, W. Kostowski, and A. Płaźnik The comparison of benzodiazepine derivatives and serotonergic agonists and antagonists in two animal model of anxiety Neuropharmacology 31 1992 1251 1258
19. K. Tada, K. Kasamo, N. Ueda, T. Suzuki, T. Koijma, and K. Ishikawa Anxiolytic 5-hydroxytryptamine1A agonists suppress firing activity of dorsal hippocampus CA1 pyramidal neurons thruough a postsynaptic mechanism: single-unit study in unanesthetized, unrestrained rats J. Pharmacol. Exp. Ther. 288 1999 843 848
20. M. Zienowicz, A. Wisłowska, M. Lehner, E. Taracha, A. Skórzewska, P. Maciejak, and A. Płaźnik The effect of fluoxetine in a model of chemically induced seizures - behavioural and immunocytochemical study Neurosci. Lett. 373 2005 226 231