-
1
-
-
0031781603
-
Inflammatory bowel disease: Etiology and pathogenesis
-
Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998; 115: 182-205
-
(1998)
Gastroenterology
, vol.115
, pp. 182-205
-
-
Fiocchi, C.1
-
4
-
-
0036105388
-
The genetic jigsaw of inflammatory bowel disease
-
Watts DA, Satsangi J. The genetic jigsaw of inflammatory bowel disease. Gut 2002; 50(Suppl 3): s31-36
-
(2002)
Gut
, vol.50
, Issue.SUPPL. 3
-
-
Watts, D.A.1
Satsangi, J.2
-
6
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, Almer S, Tysk C, O'Morain CA, Gassull M, Binder V, Finkel Y, Cortot A, Modigliani R, Laurent-Puig P, Gower-Rousseau C, Macry J, Colombel JF, Sahbatou M, Thomas G. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001; 411: 599-603
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O'Morain, C.A.9
Gassull, M.10
Binder, V.11
Finkel, Y.12
Cortot, A.13
Modigliani, R.14
Laurent-Puig, P.15
Gower-Rousseau, C.16
Macry, J.17
Colombel, J.F.18
Sahbatou, M.19
Thomas, G.20
more..
-
7
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohara M, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nunez G, Cho JH. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001; 411: 603-606
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, M.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
Achkar, J.P.11
Brant, S.R.12
Bayless, T.M.13
Kirschner, B.S.14
Hanauer, S.B.15
Nunez, G.16
Cho, J.H.17
-
8
-
-
0036306951
-
Lack of common NOD2 variants in Japanese patients with Crohn's disease
-
Inoue N, Tamura K, Kinouchi Y, Fukuda Y, Takahashi S, Ogura Y, Inohara N, Nunez G, Kishi Y, Koike Y, Shimosegawa T, Shimoyama T, Hibi T. Lack of common NOD2 variants in Japanese patients with Crohn's disease. Gastroenterology 2002; 123: 86-91
-
(2002)
Gastroenterology
, vol.123
, pp. 86-91
-
-
Inoue, N.1
Tamura, K.2
Kinouchi, Y.3
Fukuda, Y.4
Takahashi, S.5
Ogura, Y.6
Inohara, N.7
Nunez, G.8
Kishi, Y.9
Koike, Y.10
Shimosegawa, T.11
Shimoyama, T.12
Hibi, T.13
-
9
-
-
0036373539
-
Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease
-
Yamazaki K, Takazoe M, Tanaka T, Kazumori T, Nakamura U. Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease. J Hum Genet 2002; 47: 469-472
-
(2002)
J. Hum. Genet.
, vol.47
, pp. 469-472
-
-
Yamazaki, K.1
Takazoe, M.2
Tanaka, T.3
Kazumori, T.4
Nakamura, U.5
-
10
-
-
0027281895
-
Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases
-
Hein DW, Doll MA, Rustan TD, Gray K, Feng Y, Ferguson RJ, Grant DM. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. Carcinogenesis 1993; 14: 1633-1638
-
(1993)
Carcinogenesis
, vol.14
, pp. 1633-1638
-
-
Hein, D.W.1
Doll, M.A.2
Rustan, T.D.3
Gray, K.4
Feng, Y.5
Ferguson, R.J.6
Grant, D.M.7
-
11
-
-
0026040316
-
Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon
-
Turesky RJ, Land NP, Butler MA, Teitel CH, Kadlubar FF. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon. Carcinogenesis 1991; 12: 1839-1845
-
(1991)
Carcinogenesis
, vol.12
, pp. 1839-1845
-
-
Turesky, R.J.1
Land, N.P.2
Butler, M.A.3
Teitel, C.H.4
Kadlubar, F.F.5
-
12
-
-
0034128936
-
Human UDP-glucuronosyl-transferases: Metabolism, expression, and disease
-
Tukey RH, Strassburg CP. Human UDP-glucuronosyl-transferases: metabolism, expression, and disease. Annu Rev Pharmacol Toxicol 2000; 40: 581-616
-
(2000)
Annu. Rev. Pharmacol. Toxicol.
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
13
-
-
0034680792
-
Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine
-
Strassburg CP, Kneip S, Topp J, Obermayer-Straub P, Barut A, Tukey RH, Manns MP. Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine. J Biol Chem 2000; 275: 36164-36171
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36164-36171
-
-
Strassburg, C.P.1
Kneip, S.2
Topp, J.3
Obermayer-Straub, P.4
Barut, A.5
Tukey, R.H.6
Manns, M.P.7
-
14
-
-
0035115599
-
Genetic multiplicity of the human UDP-glucuronosyltransferases and regulation in the gastrointestinal tract
-
Tukey RH, Strassburg CP. Genetic multiplicity of the human UDP-glucuronosyltransferases and regulation in the gastrointestinal tract. Mol Pharmacol 2001; 59: 405-414
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 405-414
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
15
-
-
0034765595
-
Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene
-
Vogel A, Kneip S, Barut A, Ehmer U, Tukey RH, Manns MP, Strassburg CP. Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene. Gastroenterology 2001; 121: 1136-1144
-
(2001)
Gastroenterology
, vol.121
, pp. 1136-1144
-
-
Vogel, A.1
Kneip, S.2
Barut, A.3
Ehmer, U.4
Tukey, R.H.5
Manns, M.P.6
Strassburg, C.P.7
-
16
-
-
0033281951
-
Polymorphisms of the xenobiotic-metabolizing enzymes CYP1A1 and NAT-2 in systemic sclerosis and lupus erythematosus
-
von Schmiedeberg S, Fritsche E, Rönnau AC, Specker C, Golka K, Richter-Hintz D, Schuppe HC, Lehmann P, Ruzicka T, Esser C, Abel J, Gleichmann E. Polymorphisms of the xenobiotic-metabolizing enzymes CYP1A1 and NAT-2 in systemic sclerosis and lupus erythematosus. Adv Exp Med Biol 1999; 455: 147-152
-
(1999)
Adv. Exp. Med. Biol.
, vol.455
, pp. 147-152
-
-
von Schmiedeberg, S.1
Fritsche, E.2
Rönnau, A.C.3
Specker, C.4
Golka, K.5
Richter-Hintz, D.6
Schuppe, H.C.7
Lehmann, P.8
Ruzicka, T.9
Esser, C.10
Abel, J.11
Gleichmann, E.12
-
17
-
-
0034091884
-
Polymorphisms of NAT2 in relation to sulphasalazine-induced agranulocytosis
-
Wadelius M, Stjernberg E, Wiholm BE, Rane A. Polymorphisms of NAT2 in relation to sulphasalazine-induced agranulocytosis. Pharmacogenetics 2000; 10: 35-41
-
(2000)
Pharmacogenetics
, vol.10
, pp. 35-41
-
-
Wadelius, M.1
Stjernberg, E.2
Wiholm, B.E.3
Rane, A.4
-
18
-
-
0036202380
-
Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis
-
Huang YS, Chern HD, Su WJ, Wu JC, Lai SL, Yang SY, Chang FY, Lee SD. Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis. Hepatology 2002; 35: 883-889
-
(2002)
Hepatology
, vol.35
, pp. 883-889
-
-
Huang, Y.S.1
Chern, H.D.2
Su, W.J.3
Wu, J.C.4
Lai, S.L.5
Yang, S.Y.6
Chang, F.Y.7
Lee, S.D.8
-
19
-
-
0035913673
-
Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk
-
Zheng Z, Park JY, Guillemette C, Schantz SP, Lazarus P. Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk. J Natl Cancer Inst 2001; 93: 1411-1418
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, pp. 1411-1418
-
-
Zheng, Z.1
Park, J.Y.2
Guillemette, C.3
Schantz, S.P.4
Lazarus, P.5
-
20
-
-
0033104667
-
Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus
-
Strassburg CP, Strassburg A, Nguyen N, Li Q, Manns MP, Tukey RH. Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus. Biochm J 1999: 338: 489-498
-
(1999)
Biochm. J.
, vol.338
, pp. 489-498
-
-
Strassburg, C.P.1
Strassburg, A.2
Nguyen, N.3
Li, Q.4
Manns, M.P.5
Tukey, R.H.6
-
21
-
-
0034190441
-
N-acetyltransferase polymorphisms and colorectal cancer: A HuGE review
-
Brockton N, Little J, Sharp L, Cotton SC. N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review. Am J Epidemiol 2000; 151: 846-861
-
(2000)
Am. J. Epidemiol.
, vol.151
, pp. 846-861
-
-
Brockton, N.1
Little, J.2
Sharp, L.3
Cotton, S.C.4
-
22
-
-
0036101804
-
Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer
-
Strassburg CP, Vogel A, Kneip S, Tukey RH, Manns MP. Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer. Gut 2002; 50: 851-856
-
(2002)
Gut
, vol.50
, pp. 851-856
-
-
Strassburg, C.P.1
Vogel, A.2
Kneip, S.3
Tukey, R.H.4
Manns, M.P.5
-
23
-
-
0038281512
-
UDP glucuronosyltransferase (UGT1A7) gene polymorphisms increase the risk of chronic pancreatitis and pancreatic cancer
-
Ockenga J, Vogel A, Teich N, Keim V, Manns MP, Strassburg CP. UDP glucuronosyltransferase (UGT1A7) gene polymorphisms increase the risk of chronic pancreatitis and pancreatic cancer. Gastroenterology 2003; 124: 1802-1808
-
(2003)
Gastroenterology
, vol.124
, pp. 1802-1808
-
-
Ockenga, J.1
Vogel, A.2
Teich, N.3
Keim, V.4
Manns, M.P.5
Strassburg, C.P.6
-
24
-
-
0037635211
-
Polymorphism of the N-acetyltransferase 2 gene, red meat intake, and the susceptibility of hepatocellular carcinoma
-
Huang YS, Chern HD, Wu JC, Chao Y, Huang YH, Chang FY, Lee SD. Polymorphism of the N-acetyltransferase 2 gene, red meat intake, and the susceptibility of hepatocellular carcinoma. Am J Gastroenterol 2003; 98: 1417-1422
-
(2003)
Am. J. Gastroenterol.
, vol.98
, pp. 1417-1422
-
-
Huang, Y.S.1
Chern, H.D.2
Wu, J.C.3
Chao, Y.4
Huang, Y.H.5
Chang, F.Y.6
Lee, S.D.7
-
25
-
-
0028909978
-
Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer
-
Risch A, Wallace DM, Bathers S, Sim E. Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer. Hum Mol Genet 1995; 4: 231-236
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 231-236
-
-
Risch, A.1
Wallace, D.M.2
Bathers, S.3
Sim, E.4
-
26
-
-
0026432216
-
Inflammatory bowel disease (1)
-
Podolsky DK. Inflammatory bowel disease (1). N Eng J Med 1991; 325: 928-937
-
(1991)
N. Eng. J. Med.
, vol.325
, pp. 928-937
-
-
Podolsky, D.K.1
-
27
-
-
0026415351
-
Inflammatory bowel disease (2)
-
Podolsky DK. Inflammatory bowel disease (2). N Eng J Med 1991; 325: 1008-1016
-
(1991)
N. Eng. J. Med.
, vol.325
, pp. 1008-1016
-
-
Podolsky, D.K.1
-
28
-
-
0024810567
-
Classification of inflammatory bowel disease
-
Lennard-Jones JE. Classification of inflammatory bowel disease. Scand J Gastroenterol 1989; 170: 2-6
-
(1989)
Scand. J. Gastroenterol.
, vol.170
, pp. 2-6
-
-
Lennard-Jones, J.E.1
-
29
-
-
33645593098
-
-
http://www.louisville.edu/medschool/pharmacology/NAT2.html/
-
-
-
-
30
-
-
0033520939
-
Novel human N-acetyltransferase 2 alleles that differ in mechanism for slow acetylator phenotype
-
Leff MA, Fretland AJ, Doll MA, Hein DW. Novel human N-acetyltransferase 2 alleles that differ in mechanism for slow acetylator phenotype. J Biol Chem 1999; 274: 34519-34522
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34519-34522
-
-
Leff, M.A.1
Fretland, A.J.2
Doll, M.A.3
Hein, D.W.4
-
31
-
-
0034987699
-
Identification of single-nucleotide polymorphisms (SNPs) of human N-acetyltransferase genes NAT1, NAT2, AANAT, ARD1 and L1CAM in the Japanese population
-
Sekine A, Saito S, Iida A, Mitsunobu Y, Higuchi S, Harigae S, Nakamura Y. Identification of single-nucleotide polymorphisms (SNPs) of human N-acetyltransferase genes NAT1, NAT2, AANAT, ARD1 and L1CAM in the Japanese population. J Hum Genet 2001; 46: 314-319
-
(2001)
J. Hum. Genet.
, vol.46
, pp. 314-319
-
-
Sekine, A.1
Saito, S.2
Iida, A.3
Mitsunobu, Y.4
Higuchi, S.5
Harigae, S.6
Nakamura, Y.7
-
32
-
-
0035965503
-
Kinetic phenotypic diagnosis of N-acetylation polymorphism in patients based on ratio of urinary metabolites of salicylazosulfapyridine
-
Yokogawa K, Nakaharu T, Ishizaki J, Ozaki E, Takeda Y, Mabuchi H, Matsushita R, Kimura K, Nakashima E, Ichimura F, Miyamoto K. Kinetic phenotypic diagnosis of N-acetylation polymorphism in patients based on ratio of urinary metabolites of salicylazosulfapyridine. Int J Pharm 2001; 229: 183-191
-
(2001)
Int. J. Pharm.
, vol.229
, pp. 183-191
-
-
Yokogawa, K.1
Nakaharu, T.2
Ishizaki, J.3
Ozaki, E.4
Takeda, Y.5
Mabuchi, H.6
Matsushita, R.7
Kimura, K.8
Nakashima, E.9
Ichimura, F.10
Miyamoto, K.11
-
33
-
-
0036313887
-
Genetic polymorphisms of the UDP-glucuronosyltransferase 1A7 gene and irinotecan toxicity in Japanese cancer patients
-
Ando M, Ando Y, Sekido Y, Ando M, Shimokata K, Hasegawa Y. Genetic polymorphisms of the UDP-glucuronosyltransferase 1A7 gene and irinotecan toxicity in Japanese cancer patients. Jpn J Canceer Res 2002; 93: 591-597
-
(2002)
Jpn. J. Cancer Res.
, vol.93
, pp. 591-597
-
-
Ando, M.1
Ando, Y.2
Sekido, Y.3
Ando, M.4
Shimokata, K.5
Hasegawa, Y.6
-
34
-
-
0029163589
-
Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: Correlation with phenotypic activity
-
Cascorbi I, Drakoulis N, Bröckmoller J, Maurer A, Sperling K, Roots I. Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity. Am J Hum Genet 1995; 57: 581-592
-
(1995)
Am. J. Hum. Genet.
, vol.57
, pp. 581-592
-
-
Cascorbi, I.1
Drakoulis, N.2
Bröckmoller, J.3
Maurer, A.4
Sperling, K.5
Roots, I.6
-
35
-
-
0033382567
-
Distribution and concordance of N-acetyltransferase genotype and phenotype in an American population
-
Gross M, Kruisselbrink T, Anderson K, Lang N, McGovern P, Delongchamp R, Kadlubar F. Distribution and concordance of N-acetyltransferase genotype and phenotype in an American population. Cancer Epidemiol Biomarkrs Prev 1999; 8: 683-692
-
(1999)
Cancer Epidemiol. Biomarkers Prev.
, vol.8
, pp. 683-692
-
-
Gross, M.1
Kruisselbrink, T.2
Anderson, K.3
Lang, N.4
McGovern, P.5
Delongchamp, R.6
Kadlubar, F.7
-
36
-
-
0035052559
-
Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms
-
Fretland AJ, Leff MA, Doll MA, Hein DW. Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms. Pharmacogenetics 2001; 11: 207-215
-
(2001)
Pharmacogenetics
, vol.11
, pp. 207-215
-
-
Fretland, A.J.1
Leff, M.A.2
Doll, M.A.3
Hein, D.W.4
-
37
-
-
0001631407
-
Inflammatory bowel diseases: Ulcerative colitis and Crohn's disease
-
Isselbacher KJ, Braunwald E, Wilson JD, eds. 13th ed. New York: McGraw-Hill, Inc
-
Glickman RM. Inflammatory bowel diseases: ulcerative colitis and Crohn's disease. In: Isselbacher KJ, Braunwald E, Wilson JD, eds. Harrison's principles of internal medicine, 13th ed. New York: McGraw-Hill, Inc 1994: 1403-1417
-
(1994)
Harrison's Principles of Internal Medicine
, pp. 1403-1417
-
-
Glickman, R.M.1
-
38
-
-
17344376439
-
Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel disease
-
Cho JH, Nicolae DL, Ramos R, Fields CT, Rabenau K, Corradino S, Brant SR, Espinosa R, LeBeau M, Hanauer SB, Bodzin J, Bonen DK. Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel disease. Hum Mol Genet 2000; 9: 1425-1432
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1425-1432
-
-
Cho, J.H.1
Nicolae, D.L.2
Ramos, R.3
Fields, C.T.4
Rabenau, K.5
Corradino, S.6
Brant, S.R.7
Espinosa, R.8
LeBeau, M.9
Hanauer, S.B.10
Bodzin, J.11
Bonen, D.K.12
-
39
-
-
18244375904
-
Evidence for a NOD2-independent susceptibility locus for inflammatory bowel disease on chromosome 16p
-
Hampe J, Frenzel H, Mirza MM, Croucher PJ, Cuthbert A, Mascheretti S, Huse K, Platzer M, Bridger S, Meyer B, Nurnberg P, Stokkers P, Krawczak M, Mathew CG, Curran M, Schreiber S. Evidence for a NOD2-independent susceptibility locus for inflammatory bowel disease on chromosome 16p. Proc Natl Acad Sci USA 2002; 99: 321-326
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 321-326
-
-
Hampe, J.1
Frenzel, H.2
Mirza, M.M.3
Croucher, P.J.4
Cuthbert, A.5
Mascheretti, S.6
Huse, K.7
Platzer, M.8
Bridger, S.9
Meyer, B.10
Nurnberg, P.11
Stokkers, P.12
Krawczak, M.13
Mathew, C.G.14
Curran, M.15
Schreiber, S.16
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