Squaric monoamide monoester as a new class of reactive immunization hapten for catalytic antibodies

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 19, 2005, Pages 4304-4307

  Xu, Yang ^a   Yamamoto, Noboru ^a   Ruiz, Diana I ^a   Kubitz, Diane S ^a   Janda, Kim D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Catalytic antibodies; Reactive immunization; Squaric monoester monoamide

Indexed keywords

CATALYTIC ANTIBODY; HAPTEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2D4; MONOCLONAL ANTIBODY 3C8; PARAOXON; SQUARIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBODY COMBINING SITE; ARTICLE; CHEMICAL MODIFICATION; HYDROLYSIS; IMMUNIZATION; INTOXICATION; KINETICS; MOLECULAR PROBE; REACTIVE IMMUNIZATION;

AMIDES; ANIMALS; ANTIBODIES, CATALYTIC; BINDING SITES, ANTIBODY; CYCLOBUTANES; ESTERS; HAPTENS; HYDROLYSIS; KINETICS; MICE; MICE, INBRED BALB C; PARAOXON; PESTICIDES; STRUCTURE-ACTIVITY RELATIONSHIP; VACCINATION;

EID: 23944503328     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.06.052     Document Type: Article

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