Resistance mechanism development to the topoisomerase-I inhibitor Hoechst 33342 by Leishmania donovani

Parasitology

Volumn 131, Issue 2, 2005, Pages 197-206

  Marquis, J F ^a,b   Hardy, I ^a,b   Olivier, M ^a,c  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Drug resistance; Hoechst 33342; Leishmania; MGBLs; Topoisomerase I

Indexed keywords

DNA TOPOISOMERASE INHIBITOR; HOE 33342; PIBENZIMOL;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA STRAND BREAKAGE; DRUG ACCUMULATION; DRUG RESISTANCE; ENZYME MECHANISM; ENZYME SPECIFICITY; GENE; GENE EXPRESSION REGULATION; GENETIC RESISTANCE; GROWTH INHIBITION; IN VITRO STUDY; INHIBITION KINETICS; LDTOP1A GENE; LDTOP1B GENE; LEISHMANIA DONOVANI; MAMMAL CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN TRANSPORT; REGULATORY MECHANISM; STRAIN IDENTIFICATION; WILD TYPE;

ANIMALS; ANTIPROTOZOAL AGENTS; BENZIMIDAZOLES; BIOLOGICAL TRANSPORT; DNA TOPOISOMERASES, TYPE I; DRUG RESISTANCE; GENE EXPRESSION; LEISHMANIA DONOVANI;

LEISHMANIA DONOVANI; MAMMALIA;

EID: 23944493330     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0031182005007328     Document Type: Article

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