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Volumn 106, Issue 5, 2005, Pages 1742-1748

Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; CASPASE 3; CASPASE 8; CD40 ANTIGEN; CD40 LIGAND; FAS ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BID; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; X LINKED INHIBITOR OF APOPTOSIS 1540 14;

EID: 23944469907     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2005-02-0695     Document Type: Article
Times cited : (59)

References (34)
  • 1
    • 0034329352 scopus 로고    scopus 로고
    • CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia
    • Wierda WG, Cantwell MJ, Woods SJ, et al. CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia. Blood. 2000;96:2917-2924.
    • (2000) Blood , vol.96 , pp. 2917-2924
    • Wierda, W.G.1    Cantwell, M.J.2    Woods, S.J.3
  • 3
    • 17044401460 scopus 로고    scopus 로고
    • (Now available as Blood. 2005;105:3193-3198).
    • (2005) Blood , vol.105 , pp. 3193-3198
  • 4
    • 0037133603 scopus 로고    scopus 로고
    • Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemia
    • Chu P, Deforce D, Pedersen IM, et al. Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2002;99:3854-3859.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 3854-3859
    • Chu, P.1    Deforce, D.2    Pedersen, I.M.3
  • 5
    • 0030698127 scopus 로고    scopus 로고
    • The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
    • Roy N, Deveraux QL, Takahashi R, Salvesen GS, Reed JC. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 1997;16:6914-6925.
    • (1997) EMBO J , vol.16 , pp. 6914-6925
    • Roy, N.1    Deveraux, Q.L.2    Takahashi, R.3    Salvesen, G.S.4    Reed, J.C.5
  • 6
    • 0032522738 scopus 로고    scopus 로고
    • IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
    • Deveraux QL, Roy N, Stennicke HR, et al. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 1998;17:2215-2223.
    • (1998) EMBO J , vol.17 , pp. 2215-2223
    • Deveraux, Q.L.1    Roy, N.2    Stennicke, H.R.3
  • 7
    • 0036464611 scopus 로고    scopus 로고
    • The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: Evidence of caspase activation and apoptosis induction
    • Byrd JC, Kitada S, Flinn IW, et al. The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction. Blood. 2002;99:1038-1043.
    • (2002) Blood , vol.99 , pp. 1038-1043
    • Byrd, J.C.1    Kitada, S.2    Flinn, I.W.3
  • 8
    • 0032851693 scopus 로고    scopus 로고
    • Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia
    • Kitada S, Zapata JM, Andreeff M, Reed JC. Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia. Br J Haematol. 1999;106:995-1004.
    • (1999) Br J Haematol , vol.106 , pp. 995-1004
    • Kitada, S.1    Zapata, J.M.2    Andreeff, M.3    Reed, J.C.4
  • 9
    • 2942536156 scopus 로고    scopus 로고
    • Functional evaluation of the role of inhibitor of apoptosis proteins in chronic lymphocytic leukemia
    • Schliep S, Decker T, Schneller F, Wagner H, Hacker G. Functional evaluation of the role of inhibitor of apoptosis proteins in chronic lymphocytic leukemia. Exp Hematol. 2004;32:556-562.
    • (2004) Exp Hematol , vol.32 , pp. 556-562
    • Schliep, S.1    Decker, T.2    Schneller, F.3    Wagner, H.4    Hacker, G.5
  • 10
    • 0036718393 scopus 로고    scopus 로고
    • XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis
    • Bratton SB, Lewis J, Butterworth M, Duckett CS, Cohen GM. XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis. Cell Death Differ. 2002;9:881-892.
    • (2002) Cell Death Differ , vol.9 , pp. 881-892
    • Bratton, S.B.1    Lewis, J.2    Butterworth, M.3    Duckett, C.S.4    Cohen, G.M.5
  • 11
    • 8844226681 scopus 로고    scopus 로고
    • CD40 stimulation of B-cell chronic lymphocytic leukaemia cells enhances the anti-apoptotic profile, but also Bid expression and cells remain susceptible to autologous cytotoxic T-lymphocyte attack
    • Kater AP, Evers LM, Remmerswaal EB, et al. CD40 stimulation of B-cell chronic lymphocytic leukaemia cells enhances the anti-apoptotic profile, but also Bid expression and cells remain susceptible to autologous cytotoxic T-lymphocyte attack. Br J Haematol. 2004;127:404-415.
    • (2004) Br J Haematol , vol.127 , pp. 404-415
    • Kater, A.P.1    Evers, L.M.2    Remmerswaal, E.B.3
  • 12
    • 4344616982 scopus 로고    scopus 로고
    • Targeting apoptosis via chemical design: Inhibition of Bid-induced cell death by small organic molecules
    • Becattini B, Sareth S, Zhai D, et al. Targeting apoptosis via chemical design: inhibition of Bid-induced cell death by small organic molecules. Chem Biol. 2004;11:1107-1117.
    • (2004) Chem Biol , vol.11 , pp. 1107-1117
    • Becattini, B.1    Sareth, S.2    Zhai, D.3
  • 13
    • 0036141029 scopus 로고    scopus 로고
    • TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
    • Deng Y, Lin Y, Wu X. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. Genes Dev. 2002;16:33-45.
    • (2002) Genes Dev , vol.16 , pp. 33-45
    • Deng, Y.1    Lin, Y.2    Wu, X.3
  • 14
    • 0037178881 scopus 로고    scopus 로고
    • Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis
    • Li S, Zhao Y, He X, et al. Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis. J Biol Chem. 2002;277:26912-26920.
    • (2002) J Biol Chem , vol.277 , pp. 26912-26920
    • Li, S.1    Zhao, Y.2    He, X.3
  • 15
    • 0037192790 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein
    • Suni XM, Bratton SB, Butterworth M, MacFarlane M, Cohen GM. Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein. J Biol Chem. 2002;277:11345-11351.
    • (2002) J Biol Chem , vol.277 , pp. 11345-11351
    • Suni, X.M.1    Bratton, S.B.2    Butterworth, M.3    MacFarlane, M.4    Cohen, G.M.5
  • 16
    • 9144234685 scopus 로고    scopus 로고
    • Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
    • Schimmer AD, Welsh K, Pinilla C, et al. Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity. Cancer Cell. 2004;5:25-35.
    • (2004) Cancer Cell , vol.5 , pp. 25-35
    • Schimmer, A.D.1    Welsh, K.2    Pinilla, C.3
  • 17
    • 9144265592 scopus 로고    scopus 로고
    • Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors
    • Wang Z, Cuddy M, Samuel T, et al. Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors. J Biol Chem. 2004;279:48168-48176.
    • (2004) J Biol Chem , vol.279 , pp. 48168-48176
    • Wang, Z.1    Cuddy, M.2    Samuel, T.3
  • 18
    • 0035961503 scopus 로고    scopus 로고
    • Plasmids encoding granulocyte-macrophage colony-stimulating factor and CD154 enhance the immune response to genetic vaccines
    • Burger JA, Mendoza RB, Kipps TJ. Plasmids encoding granulocyte-macrophage colony-stimulating factor and CD154 enhance the immune response to genetic vaccines. Vaccine. 2001;19:2181-2189.
    • (2001) Vaccine , vol.19 , pp. 2181-2189
    • Burger, J.A.1    Mendoza, R.B.2    Kipps, T.J.3
  • 19
    • 0033542810 scopus 로고    scopus 로고
    • Reduction in mitochondrial membrane potential is an early event in Fas-independent CTL-mediated apoptosis
    • Hu D, Kipps TJ. Reduction in mitochondrial membrane potential is an early event in Fas-independent CTL-mediated apoptosis. Cell Immunol. 1999;195:43-52.
    • (1999) Cell Immunol , vol.195 , pp. 43-52
    • Hu, D.1    Kipps, T.J.2
  • 20
    • 0035353212 scopus 로고    scopus 로고
    • Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia
    • Granziero L, Ghia P, Circosta P, et al. Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia. Blood. 2001;97:2777-2783.
    • (2001) Blood , vol.97 , pp. 2777-2783
    • Granziero, L.1    Ghia, P.2    Circosta, P.3
  • 21
    • 0037314856 scopus 로고    scopus 로고
    • Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells
    • Park MT, Kang JA, Choi JA, et al. Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells. Clin Cancer Res. 2003;9:878-885.
    • (2003) Clin Cancer Res , vol.9 , pp. 878-885
    • Park, M.T.1    Kang, J.A.2    Choi, J.A.3
  • 22
    • 0037155788 scopus 로고    scopus 로고
    • Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition
    • Tafani M, Karpinich NO, Hurster KA, et al. Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition. J Biol Chem. 2002;277:10073-10082.
    • (2002) J Biol Chem , vol.277 , pp. 10073-10082
    • Tafani, M.1    Karpinich, N.O.2    Hurster, K.A.3
  • 23
    • 0034710543 scopus 로고    scopus 로고
    • Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death
    • Holcik M, Yeh C, Korneluk RG, Chow T. Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death. Oncogene. 2000;19:4174-4177.
    • (2000) Oncogene , vol.19 , pp. 4174-4177
    • Holcik, M.1    Yeh, C.2    Korneluk, R.G.3    Chow, T.4
  • 24
    • 0034104017 scopus 로고    scopus 로고
    • Apoptosis and chemoresistance in human ovarian cancer: Is Xiap a determinant?
    • Li J, Sasaki H, Sheng YL, et al. Apoptosis and chemoresistance in human ovarian cancer: is Xiap a determinant? Biol Signals Recept. 2000;9:122-130.
    • (2000) Biol Signals Recept , vol.9 , pp. 122-130
    • Li, J.1    Sasaki, H.2    Sheng, Y.L.3
  • 25
    • 0034667372 scopus 로고    scopus 로고
    • Down-regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells
    • Sasaki H, Sheng Y, Kotsuji F, Tsang BK. Down-regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells. Cancer Res. 2000;60:5659-5666.
    • (2000) Cancer Res , vol.60 , pp. 5659-5666
    • Sasaki, H.1    Sheng, Y.2    Kotsuji, F.3    Tsang, B.K.4
  • 26
    • 4344660599 scopus 로고    scopus 로고
    • Down-regulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis
    • Chawla-Sarkar M, Bae SI, Reu FJ, et al. Down-regulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ. 2004;11:915-923.
    • (2004) Cell Death Differ , vol.11 , pp. 915-923
    • Chawla-Sarkar, M.1    Bae, S.I.2    Reu, F.J.3
  • 27
    • 3843124352 scopus 로고    scopus 로고
    • Drug-mediated sensitization to TRAIL-induced apoptosis in caspase-8-complemented neuroblastoma cells proceeds via activation of intrinsic and extrinsic pathways and caspase-dependent cleavage of XIAP, Bcl-xL and RIP
    • Muhlethaler-Mottet A, Bourloud KB, Auderset K, Joseph JM, Gross N. Drug-mediated sensitization to TRAIL-induced apoptosis in caspase-8-complemented neuroblastoma cells proceeds via activation of intrinsic and extrinsic pathways and caspase-dependent cleavage of XIAP, Bcl-xL and RIP. Oncogene. 2004;23:5415-5425.
    • (2004) Oncogene , vol.23 , pp. 5415-5425
    • Muhlethaler-Mottet, A.1    Bourloud, K.B.2    Auderset, K.3    Joseph, J.M.4    Gross, N.5
  • 28
    • 3543011331 scopus 로고    scopus 로고
    • Upstream regulatory role for XIAP in receptor-mediated apoptosis
    • Wilkinson JC, Cepero E, Boise LH, Duckett CS. Upstream regulatory role for XIAP in receptor-mediated apoptosis. Mol Cell Biol. 2004;24:7003-7014.
    • (2004) Mol Cell Biol , vol.24 , pp. 7003-7014
    • Wilkinson, J.C.1    Cepero, E.2    Boise, L.H.3    Duckett, C.S.4
  • 30
    • 0034478111 scopus 로고    scopus 로고
    • Intracellular mechanisms of TRAIL and its role in cancer therapy
    • Srivastava RK. Intracellular mechanisms of TRAIL and its role in cancer therapy. Mol Cell Biol Res Commun. 2000;4:67-75.
    • (2000) Mol Cell Biol Res Commun , vol.4 , pp. 67-75
    • Srivastava, R.K.1
  • 31
    • 0034630161 scopus 로고    scopus 로고
    • The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
    • Walczak H, Krammer PH. The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res. 2000;256:58-66.
    • (2000) Exp Cell Res , vol.256 , pp. 58-66
    • Walczak, H.1    Krammer, P.H.2
  • 32
    • 1942441715 scopus 로고    scopus 로고
    • Resistance to CD95-mediated apoptosis of CD40-activated chronic lymphocytic leukemia B cells is not related to lack of DISC molecules expression
    • de Totero D, Montera M, Rosso O, et al. Resistance to CD95-mediated apoptosis of CD40-activated chronic lymphocytic leukemia B cells is not related to lack of DISC molecules expression. Hematol J. 2004;5:152-160.
    • (2004) Hematol J , vol.5 , pp. 152-160
    • Totero, D.1    Montera, M.2    Rosso, O.3
  • 33
    • 0032785181 scopus 로고    scopus 로고
    • Serial killers: Ordering caspase activation events in apoptosis
    • Slee EA, Adrain C, Martin SJ. Serial killers: ordering caspase activation events in apoptosis. Cell Death Differ. 1999;6:1067-1074.
    • (1999) Cell Death Differ , vol.6 , pp. 1067-1074
    • Slee, E.A.1    Adrain, C.2    Martin, S.J.3
  • 34
    • 0038333197 scopus 로고    scopus 로고
    • Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop
    • von Haefen C, Wieder T, Essmann F, et al. Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop. Oncogene. 2003;22:2236-2247.
    • (2003) Oncogene , vol.22 , pp. 2236-2247
    • Von Haefen, C.1    Wieder, T.2    Essmann, F.3


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