Overexpression, purification, and pharmacological activity of a biosynthetically derived conopeptide

Biochemical and Biophysical Research Communications

Volumn 335, Issue 3, 2005, Pages 965-972

  Kumar, Ganesan Senthil ^a   Ramasamy, Palanisamy ^a   Sikdar, Sujit K ^a   Sarma, Siddhartha P ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Conotoxin; Conus monile; cytb5 fusion; Heteronuclear NMR; Isotopic 15N 13C labeling of peptides; Mo1659; Potassium channels

Indexed keywords

CYTOCHROME B5; HYBRID PROTEIN; MO 1659; PHENYLALALNYLHISTIDYLGLYCYLGLYCYLSERYLTRYPTOPHYLTYROSYLARGINYLPHENYLALANYL PROLYLTRYPTOPHYLGLYCYLTYROSINE; POTASSIUM CHANNEL BLOCKING AGENT; PROLINE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

AMIDATION; AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG ACTIVITY; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

AMINO ACID SEQUENCE; BASE SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CONOTOXINS; CYANOGEN BROMIDE; CYTOCHROMES B5; DNA PRIMERS; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 23944461526     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.08.002     Document Type: Article

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