메뉴 건너뛰기




Volumn 44, Issue 5, 2005, Pages 440-448

Bortezomib: A valuable new antineoplastic strategy in multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BORTEZOMIB; DEXAMETHASONE; DOXORUBICIN; GEMCITABINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; IRINOTECAN; MELPHALAN; MITOXANTRONE; PREDNISONE; PROTEASOME; SARCOLYSIN; SOMATOMEDIN; THALIDOMIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 23944453096     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/02841860510030002     Document Type: Review
Times cited : (36)

References (50)
  • 1
    • 0242579413 scopus 로고    scopus 로고
    • Transplantation for multiple myeloma: Who, when, how often?
    • Bladé J, Vesale DH, Gertz MA. Transplantation for multiple myeloma: who, when, how often? Blood 2003;102:3469-77.
    • (2003) Blood , vol.102 , pp. 3469-3477
    • Bladé, J.1    Vesale, D.H.2    Gertz, M.A.3
  • 3
    • 0036083396 scopus 로고    scopus 로고
    • The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
    • Glickman MH, Ciechanover A. The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 2002;82:373-428.
    • (2002) Physiol Rev , vol.82 , pp. 373-428
    • Glickman, M.H.1    Ciechanover, A.2
  • 4
    • 0037852202 scopus 로고    scopus 로고
    • The proteasome: Structure, function, and role in the cell
    • Adams J. The proteasome: structure, function, and role in the cell. Cancer Treat Rev 2003;29(suppl 1):3-9.
    • (2003) Cancer Treat Rev , vol.29 , Issue.SUPPL. 1 , pp. 3-9
    • Adams, J.1
  • 5
    • 9644300915 scopus 로고    scopus 로고
    • The proteasome: A proteolytic nanomachine of cell regulation and waste disposal
    • Wolf DH, Hilt W. The proteasome: a proteolytic nanomachine of cell regulation and waste disposal. Biochim Biophys Acta 2004;1695:19-31.
    • (2004) Biochim Biophys Acta , vol.1695 , pp. 19-31
    • Wolf, D.H.1    Hilt, W.2
  • 6
    • 0037277661 scopus 로고    scopus 로고
    • Proteasome inhibitors as therapeutic agents: Current and future strategies
    • Delcros JG, Floc'h MB, Prigent C, Arlot-Bonnemains Y. Proteasome inhibitors as therapeutic agents: current and future strategies. Curr Med Chem 2003;10:479-503.
    • (2003) Curr Med Chem , vol.10 , pp. 479-503
    • Delcros, J.G.1    Floc'h, M.B.2    Prigent, C.3    Arlot-Bonnemains, Y.4
  • 7
    • 0021723091 scopus 로고
    • Inhibition of the serine proteases leukocyte elastase, pancreatic elastase, cathepsin G, and chymotrypsin by peptide boronic acids
    • Kettner CA, Shenvi AB. Inhibition of the serine proteases leukocyte elastase, pancreatic elastase, cathepsin G, and chymotrypsin by peptide boronic acids. J Biol Chem 1984;259:15106-14.
    • (1984) J Biol Chem , vol.259 , pp. 15106-15114
    • Kettner, C.A.1    Shenvi, A.B.2
  • 10
    • 2342568422 scopus 로고    scopus 로고
    • Pharmacokinetics of gemcitabine and the proteasome inhibitor bortezomib (formerly PS-341) in adult patients with solid malignancies
    • Nix D, Ryan DP, Eder JP, Fidias P, Guerciolini R, Sao N, et al. Pharmacokinetics of gemcitabine and the proteasome inhibitor bortezomib (formerly PS-341) in adult patients with solid malignancies. Proc Am Assoc Cancer Res 2003;44:1061.
    • (2003) Proc Am Assoc Cancer Res , vol.44 , pp. 1061
    • Nix, D.1    Ryan, D.P.2    Eder, J.P.3    Fidias, P.4    Guerciolini, R.5    Sao, N.6
  • 11
    • 17644379385 scopus 로고    scopus 로고
    • Pharmacology, pharmacokinetics, and practical applications of bortezomib
    • Schwartz R, Davidson T. Pharmacology, pharmacokinetics, and practical applications of bortezomib. Oncology (Huntingt) 2004;18:14-21.
    • (2004) Oncology (Huntingt) , vol.18 , pp. 14-21
    • Schwartz, R.1    Davidson, T.2
  • 12
    • 33646942589 scopus 로고    scopus 로고
    • Prescribing information available
    • VELCADE (bortezomib) for injection. Prescribing information available at http://www millennium com/products/velcade/index asp.
    • VELCADE (Bortezomib) for Injection
  • 13
    • 0037111832 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
    • Orlowski RZ, Stinchcombe TE, Mitchell BS, Shea TC, Baldwin AS, Stahl S, et al. Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. J Clin Oncol 2002;20:4420-7.
    • (2002) J Clin Oncol , vol.20 , pp. 4420-4427
    • Orlowski, R.Z.1    Stinchcombe, T.E.2    Mitchell, B.S.3    Shea, T.C.4    Baldwin, A.S.5    Stahl, S.6
  • 14
    • 0036023407 scopus 로고    scopus 로고
    • A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies
    • Aghajanian C, Soignet S, Dizon DS, Pien CS, Adams J, Elliott PJ, et al. A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies. Clin Cancer Res 2002;8:2505-11.
    • (2002) Clin Cancer Res , vol.8 , pp. 2505-2511
    • Aghajanian, C.1    Soignet, S.2    Dizon, D.S.3    Pien, C.S.4    Adams, J.5    Elliott, P.J.6
  • 15
  • 16
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T, Richardson P, Chauhan D, Palombella VJ, Elliott PJ, Adams J, et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 2001;61:3071-6.
    • (2001) Cancer Res , vol.61 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3    Palombella, V.J.4    Elliott, P.J.5    Adams, J.6
  • 17
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002;2:301-10.
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 20
    • 0037342894 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents
    • Ma MH, Yang HH, Parker K, Manyak S, Friedman JM, Altamirano C, et al. The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin Cancer Res 2003;9:1136-44.
    • (2003) Clin Cancer Res , vol.9 , pp. 1136-1144
    • Ma, M.H.1    Yang, H.H.2    Parker, K.3    Manyak, S.4    Friedman, J.M.5    Altamirano, C.6
  • 21
    • 2342613652 scopus 로고    scopus 로고
    • The proteasome: A suitable antineoplastic target
    • Adams J. The proteasome: a suitable antineoplastic target. Nat Rev Cancer 2004;4:349-60.
    • (2004) Nat Rev Cancer , vol.4 , pp. 349-360
    • Adams, J.1
  • 22
    • 0037443551 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
    • Mitsiades N, Mitsiades CS, Richardson PG, Poulaki V, Tai YT, Chauhan D, et al. The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 2003;101:2377-80.
    • (2003) Blood , vol.101 , pp. 2377-2380
    • Mitsiades, N.1    Mitsiades, C.S.2    Richardson, P.G.3    Poulaki, V.4    Tai, Y.T.5    Chauhan, D.6
  • 23
    • 0036735298 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model
    • LeBlanc R, Catley LP, Hideshima T, Lentzsch S, Mitsiades CS, Mitsiades N, et al. Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model. Cancer Res 2002;62:4996-5000.
    • (2002) Cancer Res , vol.62 , pp. 4996-5000
    • Leblanc, R.1    Catley, L.P.2    Hideshima, T.3    Lentzsch, S.4    Mitsiades, C.S.5    Mitsiades, N.6
  • 24
    • 0034902354 scopus 로고    scopus 로고
    • Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma
    • Sunwoo JB, Chen Z, Dong G, Yeh N, Crowl Bancroft C, Sausville E, et al. Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. Clin Cancer Res 2001;7:1419-28.
    • (2001) Clin Cancer Res , vol.7 , pp. 1419-1428
    • Sunwoo, J.B.1    Chen, Z.2    Dong, G.3    Yeh, N.4    Crowl Bancroft, C.5    Sausville, E.6
  • 25
    • 18244428600 scopus 로고    scopus 로고
    • Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation
    • Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant
    • Bladé J, Samson D, Reece D, Apperley J, Bjorkstrand B, Gahrton G, et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Br J Haematol 1998;102:1115-23.
    • (1998) Br J Haematol , vol.102 , pp. 1115-1123
    • Bladé, J.1    Samson, D.2    Reece, D.3    Apperley, J.4    Bjorkstrand, B.5    Gahrton, G.6
  • 27
    • 14744272160 scopus 로고    scopus 로고
    • Survival, duration of response, and time to progression with bortezomib in patients with relapsed and refractory multiple myeloma: An update with additional follow-up
    • Richardson PG, Barlogie B, Berenson J, Singhal S, Jagannath S, Irwin D, et al. Survival, duration of response, and time to progression with bortezomib in patients with relapsed and refractory multiple myeloma: An update with additional follow-up. Hematol J 2004;5(suppl 2):S103-4.
    • (2004) Hematol J , vol.5 , Issue.SUPPL. 2
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3    Singhal, S.4    Jagannath, S.5    Irwin, D.6
  • 28
    • 7044221131 scopus 로고    scopus 로고
    • Quality-of-life (QOL) and clinical benefit assessment in patients with relapsed and refractory multiple myeloma (MM) treated with bortezomib
    • Lee S, Richardson PG, Barlogie B, Berenson JR, Singhal S, Jagannath S, et al. Quality-of-life (QOL) and clinical benefit assessment in patients with relapsed and refractory multiple myeloma (MM) treated with bortezomib. Proc Am Soc Clin Oncol 2003;22:582.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 582
    • Lee, S.1    Richardson, P.G.2    Barlogie, B.3    Berenson, J.R.4    Singhal, S.5    Jagannath, S.6
  • 30
    • 21944436499 scopus 로고    scopus 로고
    • The safety of prolonged therapy with the proteasome inhibitor bortezomib (VELCADE) in relapsed and/or refractory multiple myeloma (MM)
    • Berenson JR, Jagannath S, Barlogie B, Siegel D, Alexanian R, Irwin D, et al. The safety of prolonged therapy with the proteasome inhibitor bortezomib (VELCADE) in relapsed and/or refractory multiple myeloma (MM). Hematol J 2004;5(suppl 2):S129.
    • (2004) Hematol J , vol.5 , Issue.SUPPL. 2
    • Berenson, J.R.1    Jagannath, S.2    Barlogie, B.3    Siegel, D.4    Alexanian, R.5    Irwin, D.6
  • 32
    • 21344464047 scopus 로고    scopus 로고
    • Bortezomib in combination with melphalan in the treatment of relapsed or refractory multiple myeloma: A phase I/II study
    • Berenson J, Yang H, Swift R, Sadler K, Vescio R, Adams J, et al. Bortezomib in combination with melphalan in the treatment of relapsed or refractory multiple myeloma: a phase I/II study. Blood 2004;104:64a.
    • (2004) Blood , vol.104
    • Berenson, J.1    Yang, H.2    Swift, R.3    Sadler, K.4    Vescio, R.5    Adams, J.6
  • 33
    • 23944475760 scopus 로고    scopus 로고
    • Marked activity of Velcade plus thalidomide (V+T) in advanced and refractory multiple myeloma (MM)
    • Zangari M, Barlogie B, Hollmig K, Fassas A, Rasmussen E, Thertulien R, et al. Marked activity of Velcade plus thalidomide (V+T) in advanced and refractory multiple myeloma (MM). Blood 2004;104:413a.
    • (2004) Blood , vol.104
    • Zangari, M.1    Barlogie, B.2    Hollmig, K.3    Fassas, A.4    Rasmussen, E.5    Thertulien, R.6
  • 34
    • 33846873224 scopus 로고    scopus 로고
    • Bortezomib (Velcade)+Adriamycin+ Thalidomide+Dexamethasone (VATD) as an effective regimen in patients with refractory or relapsed multiple myeloma (MM)
    • Hollmig K, Stover J, Talamo G, Fassas R, Lee CK, Anaissie E, et al. Bortezomib (Velcade)+Adriamycin+ Thalidomide+Dexamethasone (VATD) as an effective regimen in patients with refractory or relapsed multiple myeloma (MM). Blood 2004;104:659a.
    • (2004) Blood , vol.104
    • Hollmig, K.1    Stover, J.2    Talamo, G.3    Fassas, R.4    Lee, C.K.5    Anaissie, E.6
  • 35
    • 23944486566 scopus 로고    scopus 로고
    • A phase II study of Velcade (V), Doxil (D) in combination with low-dose thalidomide (T) as salvage therapy for patients with relapsed or refractory multiple myeloma (MM) and Waldenstrom macroglobulinemia (WM): Encouraging preliminary results
    • Chanan-Khan AA, Miller KC, McCarthy P, DiMiceli LA, Yu J, Bernstein ZP, et al. A phase II study of Velcade (V), Doxil (D) in combination with low-dose thalidomide (T) as salvage therapy for patients with relapsed or refractory multiple myeloma (MM) and Waldenstrom macroglobulinemia (WM): encouraging preliminary results. Blood 2004; 104:665a.
    • (2004) Blood , vol.104
    • Chanan-Khan, A.A.1    Miller, K.C.2    McCarthy, P.3    Dimiceli, L.A.4    Yu, J.5    Bernstein, Z.P.6
  • 36
    • 0346720625 scopus 로고    scopus 로고
    • Phase II trials of bortezomib in combination with dexamethasone in multiple myeloma (MM): Assessment of additional benefits to combination in patients with sub-optimal responses to bortezomib alone
    • Jagannath S, Richardson P, Barlogie B, Berenson JR, Singhal S, Irwin D, et al. Phase II trials of bortezomib in combination with dexamethasone in multiple myeloma (MM): assessment of additional benefits to combination in patients with sub-optimal responses to bortezomib alone. Proc Am Soc Clin Oncol 2003;22:582.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 582
    • Jagannath, S.1    Richardson, P.2    Barlogie, B.3    Berenson, J.R.4    Singhal, S.5    Irwin, D.6
  • 37
    • 4444298973 scopus 로고    scopus 로고
    • VTD regimen comprising Velcade (V)+thalidomide (T) and added DEX (D) for non-responders to V+T effects a 57% PR rate among 56 patients with myeloma (M) relapsing after autologous transplant
    • Zangari M, Barlogie B, Jacobson J, Rasmussen E, Burns M, Kordsmeier B, et al. VTD regimen comprising Velcade (V)+thalidomide (T) and added DEX (D) for non-responders to V+T effects a 57% PR rate among 56 patients with myeloma (M) relapsing after autologous transplant. Blood 2003;102:236a.
    • (2003) Blood , vol.102
    • Zangari, M.1    Barlogie, B.2    Jacobson, J.3    Rasmussen, E.4    Burns, M.5    Kordsmeier, B.6
  • 38
    • 20144387627 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
    • Orlowski RZ, Voorhees PM, Garcia RA, Hall MD, Kudrik FJ, Allred T, et al. Phase I trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 2005;105:3058-65.
    • (2005) Blood , vol.105 , pp. 3058-3065
    • Orlowski, R.Z.1    Voorhees, P.M.2    Garcia, R.A.3    Hall, M.D.4    Kudrik, F.J.5    Allred, T.6
  • 39
    • 21344435666 scopus 로고    scopus 로고
    • Phase II trial of single agent bortezomib (VELCADE) in patients with previously untreated multiple myeloma (MM)
    • Richardson PG, Chanan-Khan A, Schlossman RL, Munshi NC, Wen P, Briemberg H, et al. Phase II trial of single agent bortezomib (VELCADE) in patients with previously untreated multiple myeloma (MM). Blood 2004;104:100a.
    • (2004) Blood , vol.104
    • Richardson, P.G.1    Chanan-Khan, A.2    Schlossman, R.L.3    Munshi, N.C.4    Wen, P.5    Briemberg, H.6
  • 40
    • 21344434985 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib as first-line therapy in patients with multiple myeloma
    • Jagannath S, Durie B, Wolf JL, Camacho E, Irwin D, Lutzky J, et al. A phase 2 study of bortezomib as first-line therapy in patients with multiple myeloma. Blood 2004;104:98a-9a.
    • (2004) Blood , vol.104
    • Jagannath, S.1    Durie, B.2    Wolf, J.L.3    Camacho, E.4    Irwin, D.5    Lutzky, J.6
  • 41
    • 21344464281 scopus 로고    scopus 로고
    • Bortezomib (VELCADE®) plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: Preliminary results of an IFM phase II study
    • Harousseau J, Attal M, Leleu X, Gressin R, Hulin C, Fuzibet JG, et al. Bortezomib (VELCADE®) plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: preliminary results of an IFM phase II study. Blood 2004;104:416a.
    • (2004) Blood , vol.104
    • Harousseau, J.1    Attal, M.2    Leleu, X.3    Gressin, R.4    Hulin, C.5    Fuzibet, J.G.6
  • 42
    • 21344473594 scopus 로고    scopus 로고
    • PAD combination therapy (PS-341/bortezomib, Adriamycin and dexamethasone) for previously untreated patients with multiple myeloma
    • Cavenagh J, Popat R, Curry N, Stec J, Morris TC, Drake M, et al. PAD combination therapy (PS-341/bortezomib, Adriamycin and dexamethasone) for previously untreated patients with multiple myeloma. Blood 2004;104:413a.
    • (2004) Blood , vol.104
    • Cavenagh, J.1    Popat, R.2    Curry, N.3    Stec, J.4    Morris, T.C.5    Drake, M.6
  • 43
    • 21344458719 scopus 로고    scopus 로고
    • VTD (Velcade, thalidomide, dexamethasone) as primary therapy for newly-diagnosed multiple myeloma
    • Alexanian R, Wang LW, Weber DM, Delasalle KB. VTD (Velcade, thalidomide, dexamethasone) as primary therapy for newly-diagnosed multiple myeloma. Blood 2004;104:64a.
    • (2004) Blood , vol.104
    • Alexanian, R.1    Wang, L.W.2    Weber, D.M.3    Delasalle, K.B.4
  • 44
    • 21944446824 scopus 로고    scopus 로고
    • A phase I/II national, multicenter, open-label study of bortezomib plus melphalan and prednisone (V-MP) in elderly untreated multiple myeloma patients
    • Mateos MV, Bladé J, Diaz Mediavilla J, Lahuerta JJ, Terol MJ, Hernández J, et al. A phase I/II national, multicenter, open-label study of bortezomib plus melphalan and prednisone (V-MP) in elderly untreated multiple myeloma patients. Blood 2004;104:943a.
    • (2004) Blood , vol.104
    • Mateos, M.V.1    Bladé, J.2    Diaz Mediavilla, J.3    Lahuerta, J.J.4    Terol, M.J.5    Hernández, J.6
  • 45
    • 22444435861 scopus 로고    scopus 로고
    • Evaluation of the severity and risk of thrombocytopenia with bortezomib therapy in relapsed and refractory multiple myeloma
    • Lonial S, Waller EK, Richardson PG, Jagannath S, Francis D, Lehman M, et al. Evaluation of the severity and risk of thrombocytopenia with bortezomib therapy in relapsed and refractory multiple myeloma. Hematol J 2004;5(suppl 2): S130-1.
    • (2004) Hematol J , vol.5 , Issue.SUPPL. 2
    • Lonial, S.1    Waller, E.K.2    Richardson, P.G.3    Jagannath, S.4    Francis, D.5    Lehman, M.6
  • 46
    • 1942506348 scopus 로고    scopus 로고
    • Peripheral neuropathy following bortezomib (VELCADE, formerly PS-341) therapy in patients with advanced multiple myeloma (MM): Characterization and reversibility
    • Richardson P, Briemberg H, Jagannath S, Barlogie B, Berenson J, Singhal S, et al. Peripheral neuropathy following bortezomib (VELCADE, formerly PS-341) therapy in patients with advanced multiple myeloma (MM): characterization and reversibility. Blood 2003;102:149a.
    • (2003) Blood , vol.102
    • Richardson, P.1    Briemberg, H.2    Jagannath, S.3    Barlogie, B.4    Berenson, J.5    Singhal, S.6
  • 47
    • 5644266386 scopus 로고    scopus 로고
    • Tumour lysis syndrome in multiple myeloma after bortezomib (VELCADE) administration
    • Terpos E, Politou M, Rahemtulla A. Tumour lysis syndrome in multiple myeloma after bortezomib (VELCADE) administration. J Cancer Res Clin Oncol 2004;130:623-5.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 623-625
    • Terpos, E.1    Politou, M.2    Rahemtulla, A.3
  • 48
    • 1942442042 scopus 로고    scopus 로고
    • Bortezomib causes tumor lysis syndrome in approximately 1% of patients with myeloma
    • Mehta J, Jakob C, Singhal S, Stadtmauer E, Richardson P, Vesole D, et al. Bortezomib causes tumor lysis syndrome in approximately 1% of patients with myeloma. Blood 2003; 102:386b.
    • (2003) Blood , vol.102
    • Mehta, J.1    Jakob, C.2    Singhal, S.3    Stadtmauer, E.4    Richardson, P.5    Vesole, D.6
  • 49
    • 14044264214 scopus 로고    scopus 로고
    • Bortezomib-induced severe hepatitis in multiple myeloma: A case report
    • Rosiñol L, Montoto S, Cibeira MT, Bladé J. Bortezomib-induced severe hepatitis in multiple myeloma: a case report. Arch Intern Med 2005;165:464-5.
    • (2005) Arch Intern Med , vol.165 , pp. 464-465
    • Rosiñol, L.1    Montoto, S.2    Cibeira, M.T.3    Bladé, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.