Endogenous aminopeptidase N decreases the potency of peptide agonists and antagonists of the kinin B1 receptors in the rabbit aorta

Journal of Pharmacology and Experimental Therapeutics

Volumn 314, Issue 3, 2005, Pages 1169-1176

  Fortin, Jean Philippe ^a   Gera, Lajos ^c   Bouthillier, Johanne ^a   Stewart, John M ^c   Adam, Albert ^b   Marceau, François ^a  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

[LEUCINE 8]DES ARGININE 9 BRADYKININ; ALANINE 4 NITROANILIDE; AMASTATIN; ANILIDE; B 10350; BRADYKININ B1 RECEPTOR AGONIST; BRADYKININ B1 RECEPTOR ANTAGONIST; DES ARGININE 9 BRADYKININ; ENZYME INHIBITOR; LYSINE DES ARGININE 9 BRADYKININ; LYSINE[8 LEUCINE]DES ARGININE 9 BRADYKININ; LYSINE[DEXTRO 8 PHENYLALANINE]DES ARGININE 9 BRADYKININ; MICROSOMAL AMINOPEPTIDASE; N ACETYLLYSINE[8 LEUCINE]DES ARGININE 9 BRADYKININ; PEPTIDASE; PUROMYCIN; SARCOSINE[DEXTRO 8 PHENYLALANINE]DES ARGININE 9 BRADYKININ; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; AORTA CONSTRICTION; AORTA MEDIA; ARTICLE; BINDING COMPETITION; BIOASSAY; CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; DRUG POTENCY; DRUG SOLUBILITY; ENZYME INHIBITION; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; RABBIT; RATING SCALE; SMOOTH MUSCLE FIBER; STATISTICAL SIGNIFICANCE; VASCULARIZATION;

ANIMALS; ANTIGENS, CD13; AORTA; DOSE-RESPONSE RELATIONSHIP, DRUG; PEPTIDES; RABBITS; RECEPTOR, BRADYKININ B1; VASOCONSTRICTION;

EID: 23944444595     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.105.088799     Document Type: Article

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