Sequential design of a novel PVA-based crosslinked ethylenic homopolymer for extended drug delivery

International Journal of Pharmaceutics

Volumn 301, Issue 1-2, 2005, Pages 89-101

  Pillay, Viness ^a   Sibanda, Wilbert ^a   Danckwerts, Michael P ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Crosslinked ethylenic homopolymeric gelispheres; Experimental Design; Polyvinyl alcohol

Indexed keywords

AMMONIA; BORIC ACID; GLUCONATE ZINC; PECTIN; POLYMER; POLYVINYL ALCOHOL; PROPANOL; SODIUM SULFATE; ZINC; ZINC SULFATE;

ARTICLE; CROSS LINKING; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DIFFUSION; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; ENCAPSULATION; ENERGY; FORCE; KINETICS; PARAMETER; POWDER; PRIORITY JOURNAL; TEMPERATURE; TIME;

1-PROPANOL; AMMONIA; BORIC ACIDS; CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; CROSS-LINKING REAGENTS; DESICCATION; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG DESIGN; EXCIPIENTS; GELS; INDICATORS AND REAGENTS; KINETICS; PARTICLE SIZE; PECTINS; POLYETHYLENES; POLYVINYL ALCOHOL; SOLUBILITY; SULFATES; ZINC;

EID: 23944441748     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2005.05.033     Document Type: Article

References (23)

1. P. Ahlin, J. Kristl, A. Kristl, and F. Vrecer Investigation of polymeric nanoparticles as carriers of enalaprilat for oral administration Int. J. Pharm. 239 2002 113 120
2. K. Burczak, T. Fujisato, M. Hatada, and Y. Ikada Protein permeation through poly (vinyl alcohol) hydrogel membranes Biomaterials 15 1994 231 238
3. R.C. Diluccio, M.A. Hussain, D. Coffin-Beach, G. Torosian, E. Shefter, and A.R. Hurwitz Sustained-release oral delivery of theophylline by use of poly vinylalcohol and poly vinylalcohol-methyl acrylate polymers J. Pharm. Sci. 83 1994 104 106
4. M.C. Doria-Serrano, F.A. Ruiz-Trevino, C. Rios-Arciga, M. Hernandez-Esparza, and P. Santiago Physical characteristics of poly (vinyl alcohol) and calcium alginate hydrogels for the immobilization of activated sludge Biomacromolecules 2 2001 568 574
5. H.B. Hopfenberg Controlled release polymeric formulations ACS Symp. Ser. 33 1976 26 31
6. E.R. Hsu, M.S. Gebert, N.T. Becker, and A.L. Gaertner The effects of plasticizers and titanium dioxide on the properties of poly(vinyl alcohol) coatings Pharm. Dev. Technol. 6 2001 277 284
7. X. Huang, B.L. Chestang, and C.S. Brazel Minimization of initial burst in poly(vinyl alcohol) hydrogels by surface extraction and surface-preferential crosslinking Int. J. Pharm. 248 2002 183 192
8. I. Katzhendler, K. Mader, and M. Friedman Structure and hydration properties of hydroxypropyl methylcellulose matrices containing naproxen and naproxen sodium Int. J. Pharm. 200 2000 161 179
9. R.W. Korsmeyer, and N.A. Peppas Effect of the morphology of hydrophilic polymer matrices on the diffusion and release of water-soluble drugs J. Membr. Sci. 9 1981 211 227
10. A. Kotha, R.C. Raman, S. Ponrathnam, K.K. Kumar, and J.G. Shewale Beaded reactive polymers. III. Effect of triacrylates as crosslinkers on the physical properties of glycidyl methacrylate copolymers and immobilization of penicillin G acylase Appl. Biochem. Biotechnol. 74 1998 191 203
11. J. Kuntsche, K. Westesen, M. Drechsler, M.H. Koch, and H. Bunjes Supercooled smectic nanoparticles: a potential novel carrier system for poorly water soluble drugs Pharm. Res. 21 2004 1834-843
12. T.S. Kwok, B.V. Sunderland, and P.W. Heng An investigation on the influence of a vinyl pyrrolidone/vinyl acetate copolymer on the moisture permeation, mechanical and adhesive properties of aqueous-based hydroxypropyl methylcellulose film coatings Chem. Pharm. Bull. (Tokyo) 52 2004 790 796
13. A. Moretto, L. Tesolin, F. Marsilio, M. Schiavon, M. Berna, and F.M. Veronese Slow release of two antibiotics of veterinary interest from PVA hydrogels Farmaco 59 2004 1 5
14. R. Morita, R. Honda, and Y. Takahashi Development of oral controlled release preparations, a PVA swelling controlled release system (SCRS). I. Design of SCRS and its release controlling factor J. Controlled Release 63 2000 297 304
15. I. Orienti, I. Di Pietra, B. Luppi, and V. Zecchi Crosslinked polyvinylalcohol hydrogels as vehicles for hydrophilic drugs Arch. Pharm. (Weinhem) 333 2000 421 424
16. I. Orienti, R. Trere, and V. Zecchi Hydrogels formed by crosslinked polyvinylalcohol as colon-specific drug delivery systems Drug Dev. Ind. Pharm. 8 2001 877 884
17. J. Ostroha, M. Pong, A. Lowman, and N. Dan Controlling the collapse/swelling transition in charged hydrogels Biomaterials 25 2004 4345 4353
18. V. Pillay, M.P. Danckwerts, and R. Fassihi A crosslinked calcium-alginate-pectinate-cellulose acetophthalate gelisphere system for linear drug release Drug Deliv. 9 2002 77 86
19. V. Pillay, and R. Fassihi Evaluation and comparison of dissolution data derived from different modified release dosage forms: an alternative method J. Controlled Release 55 1998 45 55
20. V. Pillay, and R. Fassihi In vitro release modulation from crosslinked pellets for site-specific drug delivery to the gastrointestinal tract. I. Comparison of pH-responsive drug release and associated kinetics J. Controlled Release 59 1999 229 242
21. 2O system for drug delivery system J. Controlled Release 81 2002 367 377
22. K.S. Soppimath, A.R. Kulkarni, and T.M. Aminabhari Controlled release of antihypertensive drug from the interpenetrating network PVA-guar gum hydrogel microspheres J. Biomater. Sci. Polym. Ed. 11 2000 27 43
23. K. Yin Win, and S.S. Feng Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs Biomaterials 26 2005 2713 2722