Minimization of initial burst in poly(vinyl alcohol) hydrogels by surface extraction and surface-preferential crosslinking

International Journal of Pharmaceutics

Volumn 248, Issue 1-2, 2002, Pages 183-192

  Huang, Xiao ^a   Chestang, Brigitta L ^a   Brazel, Christopher S ^a  

^a University of Alabama   (United States)

Author keywords

Burst effect; Drug delivery; Hydrogel

Indexed keywords

POLYVINYL ALCOHOL; PROXYPHYLLINE;

ARTICLE; DRUG DIFFUSION; DRUG RELEASE; HYDROGEL; PRIORITY JOURNAL;

CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; POLYVINYL ALCOHOL; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 0037032439     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(02)00433-7     Document Type: Article

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