Hydrogels formed by cross-linked polyvinylalcohol as colon-specific drug delivery systems

Drug Development and Industrial Pharmacy

Volumn 27, Issue 8, 2001, Pages 877-884

  Orienti, I ^a   Trere R ^a   Zecchi, V ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Colon specific release; Cross linked polyvinylalcohol; Hydrogels; Hydrophilic drugs; Spray dried mixtures

Indexed keywords

ADIPOYL CHLORIDE; ALCOHOL DERIVATIVE; DICLOFENAC; POLYVINYL ALCOHOL; POLYVINYL DERIVATIVE; PROPRANOLOL; PYRIDOXINE; SEBACOYL CHLORIDE; SUCCINYL CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG MIXTURE; DRUG RELEASE; DRUG SPECIFICITY; DRUG STRUCTURE; GASTROINTESTINAL TRANSIT; HYDROGEL; HYDROPHILICITY; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; PH MEASUREMENT; POLYMERIZATION;

ALGORITHMS; CHEMISTRY, PHYSICAL; COLON; CROSS-LINKING REAGENTS; DICLOFENAC; DRUG DELIVERY SYSTEMS; HYDROGELS; MOLECULAR WEIGHT; PARTICLE SIZE; POLYVINYL ALCOHOL; PROPRANOLOL; SOLUTIONS; VITAMIN B 6;

EID: 0034759639     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-100107253     Document Type: Article

References (17)

1. Enteral insulin delivery by microspheres in three different formulations using eudragit 100 and S100
2. Formulation and in vitro and in vivo availability of diclofenac sodium enteric-coated beads
3. Formulation and in vitro evaluation of ibuprofen-carbopol 974P-NF controlled release tablets III: Influence of co-excipients on release rate of the drug
4. Enteric polymers as binders and coating materials in multiple-unit site-specific drug delivery systems
5. Organic acids as excipients in matrix granules for colon-specific drug delivery
6. A pH-dependent colon targeted oral drug delivery system using methacrylic acid copolymers. I. Manipulation of drug release using eudragit L100-55 and eudragit S100 combinations
7. A new approach to the oral administration of insulin and other peptide drugs
8. Hydrogels for site-specific drug delivery to the colon: In vitro and in vivo degradation
9. Chondroitin sulfate: A potential biodegradable carrier for colon-specific drug delivery
10. Studies on pectin formulations for colonic drug delivery
11. Drug glycosides: Potential prodrugs for colon-specific drug delivery
12. A colon-specific drug delivery system based on drug gand the glycosidases of colonic bacteria
13. Time-dependent oral delivery systems for colon targeting
14. The time clock system: A new oral dosage form for fast and complete release of drug after a predetermined lag time
15. Analysis of non-fickian transport in polymers using simplified exponential expressions