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Volumn 109, Issue 3, 2005, Pages 314-320

Mutation analysis of DKK1 and in vivo evidence of predominant p53-independent DKK1 function in gliomas

Author keywords

DKK1; Glioma; Mutation analysis; p53

Indexed keywords

BETA CATENIN; DICKKOPF 1 PROTEIN; GLYCOPROTEIN; MESSENGER RNA; PROTEIN P53; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 23844550973     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-004-0969-1     Document Type: Article
Times cited : (10)

References (36)
  • 1
    • 0037473082 scopus 로고    scopus 로고
    • AXIN1 mutations but not deletions in cerebellar medulloblastomas
    • 10.1038/sj.onc.1206156
    • Baeza N, Masuoka J, Kleihues P, Ohgaki H (2003) AXIN1 mutations but not deletions in cerebellar medulloblastomas. Oncogene 22:632-636 10.1038/ sj.onc.1206156
    • (2003) Oncogene , vol.22 , pp. 632-636
    • Baeza, N.1    Masuoka, J.2    Kleihues, P.3    Ohgaki, H.4
  • 4
    • 0037348455 scopus 로고    scopus 로고
    • APC, beta-catenin and hTCF-4; an unholy trinity in the genesis of colorectal cancer
    • 10.1053/ejso.2002.1331
    • Bright-Thomas RM, Hargest R (2003) APC, beta-catenin and hTCF-4; an unholy trinity in the genesis of colorectal cancer. Eur J Surg Oncol 29:107-117 10.1053/ejso.2002.1331
    • (2003) Eur. J. Surg. Oncol. , vol.29 , pp. 107-117
    • Bright-Thomas, R.M.1    Hargest, R.2
  • 5
    • 0034671532 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells
    • 10.1074/jbc.M007212200
    • Francis JM, Heyworth CM, Spooncer E, Pierce A, Dexter TM, Whetton AD (2000) Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells. J Biol Chem 275:39137-39145 10.1074/jbc.M007212200
    • (2000) J. Biol. Chem. , vol.275 , pp. 39137-39145
    • Francis, J.M.1    Heyworth, C.M.2    Spooncer, E.3    Pierce, A.4    Dexter, T.M.5    Whetton, A.D.6
  • 7
    • 0032556910 scopus 로고    scopus 로고
    • Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
    • 10.1038/34848
    • Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C (1998) Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391:357-362 10.1038/34848
    • (1998) Nature , vol.391 , pp. 357-362
    • Glinka, A.1    Wu, W.2    Delius, H.3    Monaghan, A.P.4    Blumenstock, C.5    Niehrs, C.6
  • 8
    • 0036500653 scopus 로고    scopus 로고
    • The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death
    • Grotewold L, Ruther U (2002) The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death. EMBO J 21:966-975
    • (2002) EMBO J. , vol.21 , pp. 966-975
    • Grotewold, L.1    Ruther, U.2
  • 9
    • 0032492954 scopus 로고    scopus 로고
    • Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta
    • 1:CAS:528:DyaK1cXjtFygur8%3D
    • Hart MJ, Santos R de los, Albert IN, Rubinfeld B, Polakis P (1998) Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. Curr Biol 8:573-581 1:CAS:528:DyaK1cXjtFygur8%3D
    • (1998) Curr. Biol. , vol.8 , pp. 573-581
    • Hart, M.J.1    de los Santos, R.2    Albert, I.N.3    Rubinfeld, B.4    Polakis, P.5
  • 10
    • 0031013879 scopus 로고    scopus 로고
    • A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo
    • 10.1073/pnas.94.1.242
    • Hayashi S, Rubinfeld B, Souza B, Polakis P, Wieschaus E, Levine AJ (1997) A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo. Proc Natl Acad Sci USA 94:242-247 10.1073/pnas.94.1.242
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 242-247
    • Hayashi, S.1    Rubinfeld, B.2    Souza, B.3    Polakis, P.4    Wieschaus, E.5    Levine, A.J.6
  • 11
    • 0034527951 scopus 로고    scopus 로고
    • The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning
    • 1:CAS:528:DC%2BD3cXptVWrtb0%3D
    • Kazanskaya O, Glinka A, Niehrs C (2000) The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning. Development 127:4981-4992 1:CAS:528:DC%2BD3cXptVWrtb0%3D
    • (2000) Development , vol.127 , pp. 4981-4992
    • Kazanskaya, O.1    Glinka, A.2    Niehrs, C.3
  • 13
    • 0032601166 scopus 로고    scopus 로고
    • Primary and secondary glioblastomas: From concept to clinical diagnosis
    • Kleihues P, Ohgaki H (1999) Primary and secondary glioblastomas: From concept to clinical diagnosis. Neuro-Oncology 1:44-51
    • (1999) Neuro-Oncology , vol.1 , pp. 44-51
    • Kleihues, P.1    Ohgaki, H.2
  • 16
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • 1:CAS:528:DC%2BD3cXls1yqsbc%3D
    • Polakis P (2000) Wnt signaling and cancer. Genes Dev 14:1837-1851 1:CAS:528:DC%2BD3cXls1yqsbc%3D
    • (2000) Genes Dev. , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 17
    • 0347623215 scopus 로고    scopus 로고
    • Molecular basis of the brain tumor-polyposis (Turcot) syndrome
    • 10.1007/s10024-003-7068-5
    • Qualman SJ, Bowen J, Erdman SH (2003) Molecular basis of the brain tumor-polyposis (Turcot) syndrome. Pediatr Dev Pathol 6:574-576 10.1007/ s10024-003-7068-5
    • (2003) Pediatr. Dev. Pathol. , vol.6 , pp. 574-576
    • Qualman, S.J.1    Bowen, J.2    Erdman, S.H.3
  • 19
    • 0033819906 scopus 로고    scopus 로고
    • The genomic structure, chromosome location, and analysis of the human DKK1 head inducer gene as a candidate for holoprosencephaly
    • 10.1159/000015618
    • Roessler E, Du Y, Glinka A, Dutra A, Niehrs C, Muenke M (2000) The genomic structure, chromosome location, and analysis of the human DKK1 head inducer gene as a candidate for holoprosencephaly. Cytogenet Cell Genet 89:220-224 10.1159/000015618
    • (2000) Cytogenet. Cell Genet. , vol.89 , pp. 220-224
    • Roessler, E.1    Du, Y.2    Glinka, A.3    Dutra, A.4    Niehrs, C.5    Muenke, M.6
  • 20
    • 0034808019 scopus 로고    scopus 로고
    • Down-regulation of beta-catenin by activated p53
    • 10.1128/MCB.21.20.6768-6781.2001
    • Sadot E, Geiger B, Oren M, Ben-Ze'ev A (2001) Down-regulation of beta-catenin by activated p53. Mol Cell Biol 21:6768-6781 10.1128/ MCB.21.20.6768-6781.2001
    • (2001) Mol. Cell Biol. , vol.21 , pp. 6768-6781
    • Sadot, E.1    Geiger, B.2    Oren, M.3    Ben-Ze'ev, A.4
  • 22
    • 0032539945 scopus 로고    scopus 로고
    • Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription
    • 10.1073/pnas.95.6.3020
    • Sakanaka C, Weiss JB, Williams LT (1998) Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription. Proc Natl Acad Sci USA 95:3020-3023 10.1073/pnas.95.6.3020
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3020-3023
    • Sakanaka, C.1    Weiss, J.B.2    Williams, L.T.3
  • 24
    • 0035252543 scopus 로고    scopus 로고
    • Wnt antagonism initiates cardiogenesis in Xenopus laevis
    • 10.1101/gad.855601
    • Schneider VA, Mercola M (2001) Wnt antagonism initiates cardiogenesis in Xenopus laevis. Genes Dev 15:304-315 10.1101/gad.855601
    • (2001) Genes Dev. , vol.15 , pp. 304-315
    • Schneider, V.A.1    Mercola, M.2
  • 26
    • 85047699343 scopus 로고    scopus 로고
    • Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA
    • 10.1038/sj.onc.1205138
    • Shou J, Ali-Osman F, Multani AS, Pathak S, Fedi P, Srivenugopal KS (2002) Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA. Oncogene 21:878-889 10.1038/ sj.onc.1205138
    • (2002) Oncogene , vol.21 , pp. 878-889
    • Shou, J.1    Ali-Osman, F.2    Multani, A.S.3    Pathak, S.4    Fedi, P.5    Srivenugopal, K.S.6
  • 28
    • 0034834570 scopus 로고    scopus 로고
    • High frequency of beta-catenin mutations in hepatoblastoma
    • 10.1007/s003830000576
    • Udatsu Y, Kusafuka T, Kuroda S, Miao J, Okada A (2001) High frequency of beta-catenin mutations in hepatoblastoma. Pediatr Surg Int 17:508-512 10.1007/s003830000576
    • (2001) Pediatr. Surg. Int. , vol.17 , pp. 508-512
    • Udatsu, Y.1    Kusafuka, T.2    Kuroda, S.3    Miao, J.4    Okada, A.5
  • 29
    • 0027714732 scopus 로고
    • A rapid and non-radioactive PCR based assay for the detection of allelic loss in human gliomas
    • Von Deimling A, Bender B, Louis DN, Wiestler OD (1993) A rapid and non-radioactive PCR based assay for the detection of allelic loss in human gliomas. Neuropathol Appl Neurobiol 19:524-529
    • (1993) Neuropathol. Appl. Neurobiol. , vol.19 , pp. 524-529
    • Von Deimling, A.1    Bender, B.2    Louis, D.N.3    Wiestler, O.D.4
  • 30
    • 0034732151 scopus 로고    scopus 로고
    • Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53
    • 10.1038/sj.onc.1203503
    • Wang J, Shou J, Chen X (2000) Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53. Oncogene 19:1843-1848 10.1038/ sj.onc.1203503
    • (2000) Oncogene , vol.19 , pp. 1843-1848
    • Wang, J.1    Shou, J.2    Chen, X.3
  • 31
    • 0030068938 scopus 로고    scopus 로고
    • A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled
    • 1:CAS:528:DyaK28XhtlSmtbY%3D
    • Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (1996) A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J Biol Chem 271:4468-4476 1:CAS:528:DyaK28XhtlSmtbY%3D
    • (1996) J. Biol. Chem. , vol.271 , pp. 4468-4476
    • Wang, Y.1    Macke, J.P.2    Abella, B.S.3    Andreasson, K.4    Worley, P.5    Gilbert, D.J.6    Copeland, N.G.7    Jenkins, N.A.8    Nathans, J.9
  • 32
    • 0033948526 scopus 로고    scopus 로고
    • Sequence variants of the axin gene in breast, colon, and other cancers: An analysis of mutations that interfere with GSK3 binding
    • Webster MT, Rozycka M, Sara E, Davis E, Smalley M, Young N, Dale TC, Wooster R (2000) Sequence variants of the axin gene in breast, colon, and other cancers: An analysis of mutations that interfere with GSK3 binding. Genes Chromosomes Cancer 28:443-453
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 443-453
    • Webster, M.T.1    Rozycka, M.2    Sara, E.3    Davis, E.4    Smalley, M.5    Young, N.6    Dale, T.C.7    Wooster, R.8
  • 33
    • 0036300610 scopus 로고    scopus 로고
    • RNA surveillance by nuclear scanning?
    • 10.1038/ncb0602-e144
    • Wilkinson MF, Shyu AB (2002) RNA surveillance by nuclear scanning? Nat Cell Biol 4: E144-147 10.1038/ncb0602-e144
    • (2002) Nat. Cell Biol. , vol.4
    • Wilkinson, M.F.1    Shyu, A.B.2
  • 34
    • 0037344296 scopus 로고    scopus 로고
    • Overexpression of human Dickkopf-1, an antagonist of wingless/WNT signaling, in human hepatoblastomas and Wilms' tumors
    • 1:CAS:528:DC%2BD3sXhvF2qtbc%3D
    • Wirths O, Waha A, Weggen S, Schirmacher P, Kuhne T, Goodyer CG, Albrecht S, Von Schweinitz D, Pietsch T (2003) Overexpression of human Dickkopf-1, an antagonist of wingless/WNT signaling, in human hepatoblastomas and Wilms' tumors. Lab Invest 83:429-434 1:CAS:528:DC%2BD3sXhvF2qtbc%3D
    • (2003) Lab. Invest. , vol.83 , pp. 429-434
    • Wirths, O.1    Waha, A.2    Weggen, S.3    Schirmacher, P.4    Kuhne, T.5    Goodyer, C.G.6    Albrecht, S.7    Von Schweinitz, D.8    Pietsch, T.9
  • 35
    • 0029925820 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 induces apoptosis in gastric cancer cells through a p53-independent pathway
    • Yamamoto M, Maehara Y, Sakaguchi Y, Kusumoto T, Ichiyoshi Y, Sugimachi K (1996) Transforming growth factor-beta 1 induces apoptosis in gastric cancer cells through a p53-independent pathway. Cancer 77:1628-1633
    • (1996) Cancer , vol.77 , pp. 1628-1633
    • Yamamoto, M.1    Maehara, Y.2    Sakaguchi, Y.3    Kusumoto, T.4    Ichiyoshi, Y.5    Sugimachi, K.6
  • 36
    • 0029046712 scopus 로고
    • A human homologue of the Drosophila polarity gene frizzled has been identified and mapped to 17q21.1
    • 10.1006/geno.1995.1060
    • Zhao Z, Lee CC, Baldini A, Caskey CT (1995) A human homologue of the Drosophila polarity gene frizzled has been identified and mapped to 17q21.1. Genomics 27:370-373 10.1006/geno.1995.1060
    • (1995) Genomics , vol.27 , pp. 370-373
    • Zhao, Z.1    Lee, C.C.2    Baldini, A.3    Caskey, C.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.