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Volumn 167, Issue 34, 2005, Pages 3152-3156

P2 purinergic receptors: Their regulation of bone metabolism and their therapeutic potential;P2-purinerge receptorer: Regulation af knogleomsætningen og terapeutisk potentiale?

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOTIDE; PURINE P2 RECEPTOR; PURINE P2X RECEPTOR; PURINE P2Y RECEPTOR;

EID: 23844548402     PISSN: 00415782     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (1)

References (31)
  • 1
    • 0015313630 scopus 로고
    • Atropine resistant excitation of the urinary bladder: The possibility of transmission via nerves releasing a purine nucleotide
    • Burnstock G, Dumsday B, Smythe A. Atropine resistant excitation of the urinary bladder: the possibility of transmission via nerves releasing a purine nucleotide. Br J Pharmacol 1972;44:451-61.
    • (1972) Br J Pharmacol , vol.44 , pp. 451-461
    • Burnstock, G.1    Dumsday, B.2    Smythe, A.3
  • 2
    • 0036510537 scopus 로고    scopus 로고
    • Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2X7 receptors
    • Jorgensen NR, Henriksen Z, Sorensen OH et al. Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2X7 receptors. J Biol Chem 2002;277:7574-80.
    • (2002) J Biol Chem , vol.277 , pp. 7574-7580
    • Jorgensen, N.R.1    Henriksen, Z.2    Sorensen, O.H.3
  • 3
    • 0030776894 scopus 로고    scopus 로고
    • ATP- And gap junction-dependent intercellular calcium signaling in osteoblastic cells
    • Jorgensen NR, Geist ST, Civitelli R et al. ATP- and gap junction-dependent intercellular calcium signaling in osteoblastic cells. J Cell Biol 1997;139:497-506.
    • (1997) J Cell Biol , vol.139 , pp. 497-506
    • Jorgensen, N.R.1    Geist, S.T.2    Civitelli, R.3
  • 4
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • Ralevic V, Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev 1998;50:413-92.
    • (1998) Pharmacol Rev , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 5
    • 0029995730 scopus 로고    scopus 로고
    • P2X receptors: An emerging channel family
    • Buell G, Collo G, Rassendren F. P2X receptors: an emerging channel family. Eur J Neurosci 1996;8:2221-8.
    • (1996) Eur J Neurosci , vol.8 , pp. 2221-2228
    • Buell, G.1    Collo, G.2    Rassendren, F.3
  • 6
    • 0037068428 scopus 로고    scopus 로고
    • Purine and pyrimidine (P2) receptors as drug targets
    • Jacobson KA, Jarvis MF, Williams M. Purine and pyrimidine (P2) receptors as drug targets. J Med Chem 2002;45:4057-93.
    • (2002) J Med Chem , vol.45 , pp. 4057-4093
    • Jacobson, K.A.1    Jarvis, M.F.2    Williams, M.3
  • 7
    • 0029140433 scopus 로고
    • P2-purinergic receptors: Subtype-associated signaling responses and structure
    • Harden TK, Boyer JL, Nicholas RA. P2-purinergic receptors: subtype-associated signaling responses and structure. Annu Rev Pharmacol Toxicol 1995;35:541-79.
    • (1995) Annu Rev Pharmacol Toxicol , vol.35 , pp. 541-579
    • Harden, T.K.1    Boyer, J.L.2    Nicholas, R.A.3
  • 8
    • 0027661421 scopus 로고
    • Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides
    • Dubyak GR, el MC. Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am J Physiol 1993;265:C577-606.
    • (1993) Am J Physiol , vol.265
    • Dubyak, G.R.1    El, M.C.2
  • 9
    • 0035046976 scopus 로고    scopus 로고
    • Extracellular nucleotide signaling: A mechanism for integrating local and systemic responses in the activation of bone remodeling
    • Bowler WB, Buckley KA, Gartland A et al. Extracellular nucleotide signaling: a mechanism for integrating local and systemic responses in the activation of bone remodeling. Bone, 2001;28:507-12.
    • (2001) Bone , vol.28 , pp. 507-512
    • Bowler, W.B.1    Buckley, K.A.2    Gartland, A.3
  • 10
    • 0034081759 scopus 로고    scopus 로고
    • P2 purinergic receptors on osteoblasts and osteoclasts: Potential targets for drug development
    • Dixon SJ, Sims SM. P2 purinergic receptors on osteoblasts and osteoclasts: Potential targets for drug development. Drug Dev Res 2000;49:187-200.
    • (2000) Drug Dev Res , vol.49 , pp. 187-200
    • Dixon, S.J.1    Sims, S.M.2
  • 11
    • 0026612137 scopus 로고
    • Evidence for P2-purinoceptors on human osteoblast-like cells
    • Schofl C, Cuthbertson KS, Walsh CA et al. Evidence for P2-purinoceptors on human osteoblast-like cells. J Bone Miner Res 1992;7:485-91.
    • (1992) J Bone Miner Res , vol.7 , pp. 485-491
    • Schofl, C.1    Cuthbertson, K.S.2    Walsh, C.A.3
  • 12
    • 0028989330 scopus 로고
    • G protein-coupled P2 purinoceptors: From molecular biology to functional responses
    • Boarder MR, Weisman GA, Turner JT et al. G protein-coupled P2 purinoceptors: from molecular biology to functional responses. Trends Pharmacol Sci 1995;16:133-9.
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 133-139
    • Boarder, M.R.1    Weisman, G.A.2    Turner, J.T.3
  • 13
    • 0031576408 scopus 로고    scopus 로고
    • Cloning of P2Y6 cDNAs and identification of a pseudogene: Comparison of P2Y receptor subtype expression in bone and brain tissues
    • Maier R, Glatz A, Mosbacher J et al. Cloning of P2Y6 cDNAs and identification of a pseudogene: comparison of P2Y receptor subtype expression in bone and brain tissues. Biochem Biophys Res Commun 1997;240:298-302.
    • (1997) Biochem Biophys Res Commun , vol.240 , pp. 298-302
    • Maier, R.1    Glatz, A.2    Mosbacher, J.3
  • 14
    • 0033851335 scopus 로고    scopus 로고
    • ATP activates DNA synthesis by acting on P2X receptors in human osteoblast-like MG-63 cells
    • Nakamura E, Uezono Y, Narusawa K et al. ATP activates DNA synthesis by acting on P2X receptors in human osteoblast-like MG-63 cells. Am J Physiol Cell Physiol 2000;279:C510-9.
    • (2000) Am J Physiol Cell Physiol , vol.279
    • Nakamura, E.1    Uezono, Y.2    Narusawa, K.3
  • 15
    • 0030935946 scopus 로고    scopus 로고
    • Effects of extracellular nucleotides on single cells and populations of human osteoblasts: Contribution of cell heterogeneity to relative potencies
    • Dixon CJ, Bowler WB, Walsh CA et al. Effects of extracellular nucleotides on single cells and populations of human osteoblasts: contribution of cell heterogeneity to relative potencies. Br J Pharmacol 1997;120:777-80.
    • (1997) Br J Pharmacol , vol.120 , pp. 777-780
    • Dixon, C.J.1    Bowler, W.B.2    Walsh, C.A.3
  • 16
    • 0041709201 scopus 로고    scopus 로고
    • Release and interconversion of P2 receptor agonists by human osteoblast-like cells
    • Buckley KA, Golding SL, Rice JM et al. Release and interconversion of P2 receptor agonists by human osteoblast-like cells. FASEB J 2003;17:1401-10.
    • (2003) FASEB J , vol.17 , pp. 1401-1410
    • Buckley, K.A.1    Golding, S.L.2    Rice, J.M.3
  • 17
    • 0030656389 scopus 로고    scopus 로고
    • Purinergic transmitters inhibit bone formation by cultured osteoblasts
    • Jones SJ, Gray C, Boyde A et al. Purinergic transmitters inhibit bone formation by cultured osteoblasts. Bone 1997;21:393-9.
    • (1997) Bone , vol.21 , pp. 393-399
    • Jones, S.J.1    Gray, C.2    Boyde, A.3
  • 18
    • 0002863742 scopus 로고
    • Metabolic and structural changes within osteocytes of rat bone
    • Talmage RV, Munson PL, eds. Amsterdam: Excerptas Media
    • Doty SB, Schofield BH. Metabolic and structural changes within osteocytes of rat bone. I: Talmage RV, Munson PL, eds. Calcium, parathyroid hormone and the calcitonins. Amsterdam: Excerptas Media, 1972:353-64.
    • (1972) Calcium, Parathyroid Hormone and the Calcitonins , pp. 353-364
    • Doty, S.B.1    Schofield, B.H.2
  • 19
    • 0036935593 scopus 로고    scopus 로고
    • ATP and UTP at low concentrations strongly inhibit bone formation by osteoblasts: A novel role for the P2Y2 receptor in bone remodeling
    • Hoebertz A, Mahendran S, Burnstock G et al. ATP and UTP at low concentrations strongly inhibit bone formation by osteoblasts: a novel role for the P2Y2 receptor in bone remodeling. J Cell Biochem 2002;86:413-9.
    • (2002) J Cell Biochem , vol.86 , pp. 413-419
    • Hoebertz, A.1    Mahendran, S.2    Burnstock, G.3
  • 20
    • 0028970146 scopus 로고
    • Extracellular nucleotides potentiate the cytosolic Ca2+, but not cyclic adenosine 3′,5′-monophosphate response to parathyroid hormone in rat osteoblastic cells
    • Kaplan AD, Reimer WJ, Feldman RD et al. Extracellular nucleotides potentiate the cytosolic Ca2+, but not cyclic adenosine 3′,5′- monophosphate response to parathyroid hormone in rat osteoblastic cells. Endocrinology 1995;136:1674-85.
    • (1995) Endocrinology , vol.136 , pp. 1674-1685
    • Kaplan, A.D.1    Reimer, W.J.2    Feldman, R.D.3
  • 21
    • 0034120397 scopus 로고    scopus 로고
    • Human osteoblastic cells propagate intercellular calcium signals by two different mechanisms
    • Jorgensen NR, Henriksen Z, Brot C et al. Human osteoblastic cells propagate intercellular calcium signals by two different mechanisms. J Bone Miner Res 2000;15:1024-32.
    • (2000) J Bone Miner Res , vol.15 , pp. 1024-1032
    • Jorgensen, N.R.1    Henriksen, Z.2    Brot, C.3
  • 22
    • 0036861712 scopus 로고    scopus 로고
    • Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-kappaB ligand
    • Buckley KA, Hipskind RA, Gartland A et al. Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-kappaB ligand. Bone 2002;31:582-90.
    • (2002) Bone , vol.31 , pp. 582-590
    • Buckley, K.A.1    Hipskind, R.A.2    Gartland, A.3
  • 23
    • 0003982630 scopus 로고    scopus 로고
    • ATP is a potent stimulator of the activation and formation of rodent osteoclasts
    • Morrison MS, Turin L, King BF et al. ATP is a potent stimulator of the activation and formation of rodent osteoclasts. J Physiol 1998;511:495-500.
    • (1998) J Physiol , vol.511 , pp. 495-500
    • Morrison, M.S.1    Turin, L.2    King, B.F.3
  • 24
    • 24944492691 scopus 로고    scopus 로고
    • P2-mediated responses in osteoclasts and osteoclast-like cells
    • Steinberg TH, Jorgensen NR, Bong JS et al. P2-mediated responses in osteoclasts and osteoclast-like cells. Drug Dev Res 2000;49.
    • (2000) Drug Dev Res , vol.49
    • Steinberg, T.H.1    Jorgensen, N.R.2    Bong, J.S.3
  • 25
    • 0025084024 scopus 로고
    • H(+)-stimulated release of prostaglandin E2 and cyclic adenosine 3′,5′-monophosphoric acid and their relationship to bone resorption in neonatal mouse calvaria cultures
    • Rabadjija L, Brown EM, Swartz SL et al. H(+)-stimulated release of prostaglandin E2 and cyclic adenosine 3′,5′-monophosphoric acid and their relationship to bone resorption in neonatal mouse calvaria cultures. Bone Miner 1990;11:295-304.
    • (1990) Bone Miner , vol.11 , pp. 295-304
    • Rabadjija, L.1    Brown, E.M.2    Swartz, S.L.3
  • 26
    • 0030757928 scopus 로고    scopus 로고
    • Spontaneous cell fusion in macrophage cultures expressing high levels of the P2Z/P2X7 receptor (published erratum appears in J Cell Biol 1997 Oct 20;139:following 571)
    • Chiozzi P, Sanz JM, Ferrari D et al. Spontaneous cell fusion in macrophage cultures expressing high levels of the P2Z/P2X7 receptor (published erratum appears in J Cell Biol 1997 Oct 20;139:following 571). J Cell Biol 1997;138:697-706.
    • (1997) J Cell Biol , vol.138 , pp. 697-706
    • Chiozzi, P.1    Sanz, J.M.2    Ferrari, D.3
  • 27
    • 0027074294 scopus 로고
    • Characterization of the cytotoxic effect of extracellular ATP in J774 mouse macrophages
    • Murgia M, Pizzo P, Steinberg TH et al. Characterization of the cytotoxic effect of extracellular ATP in J774 mouse macrophages. Biochem J 1992;288:897-901.
    • (1992) Biochem J , vol.288 , pp. 897-901
    • Murgia, M.1    Pizzo, P.2    Steinberg, T.H.3
  • 28
    • 0037634326 scopus 로고    scopus 로고
    • Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption
    • Ke HZ, Qi H, Weidema AF et al. Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption. Mol Endocrinol 2003;17:1356-67.
    • (2003) Mol Endocrinol , vol.17 , pp. 1356-1367
    • Ke, H.Z.1    Qi, H.2    Weidema, A.F.3
  • 29
    • 0026484865 scopus 로고
    • Suramin inhibits bone resorption and reduces osteoblast number in a neonatal mouse calvarial bone resorption assay
    • Walther MM, Kragel PJ, Trahan E et al. Suramin inhibits bone resorption and reduces osteoblast number in a neonatal mouse calvarial bone resorption assay. Endocrinology 1992;131:2263-70.
    • (1992) Endocrinology , vol.131 , pp. 2263-2270
    • Walther, M.M.1    Kragel, P.J.2    Trahan, E.3
  • 30
    • 0027717009 scopus 로고
    • Suramin is a potent inhibitor of calcemic hormone- And growth factor-induced bone resorption in vitro
    • Farsoudi KH, Pietschmann P, Cross HS et al. Suramin is a potent inhibitor of calcemic hormone- and growth factor-induced bone resorption in vitro. J Pharmacol Exp Ther 1993;264:579-83.
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 579-583
    • Farsoudi, K.H.1    Pietschmann, P.2    Cross, H.S.3
  • 31
    • 0028944109 scopus 로고
    • Suramin suppresses hypercalcemia and osteoclastic bone resorption in nude mice bearing a human squamous cancer
    • Yoneda T, Williams P, Rhine C et al. Suramin suppresses hypercalcemia and osteoclastic bone resorption in nude mice bearing a human squamous cancer. Cancer Res 1995;55:1989-93.
    • (1995) Cancer Res , vol.55 , pp. 1989-1993
    • Yoneda, T.1    Williams, P.2    Rhine, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.