A restraint-free small animal SPECT imaging system with motion tracking

IEEE Transactions on Nuclear Science

Volumn 52, Issue 3 I, 2005, Pages 638-644

  Weisenberger, A G ^a   Gleason, S S ^b   Goddard, J ^b   Kross, B ^a   Majewski, S ^a   Meikle, S R ^c   Paulus, M J ^b   Pomper, M ^d   Popov, V ^a   Smith, M F ^a   Welch, B L ^a   Wojcik, R ^a  

^a THOMAS JEFFERSON NATIONAL ACCELERATOR FACILITY   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Motion tracking; Multimodality imaging; Small animal single photon emission computed tomography (SPECT)

Indexed keywords

ANALOG TO DIGITAL CONVERSION; ARRAYS; GAMMA RAYS; OPTICAL COLLIMATORS; PHOSPHORS; PROFILOMETRY; RADIOACTIVE TRACERS; SENSORS; TRACKING (POSITION);

MOTION TRACKING; MULTIMODALITY IMAGING; RADIOLABELED TRACERS; SMALL ANIMAL SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY (SPECT);

IMAGING SYSTEMS;

EID: 23844493100     PISSN: 00189499     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNS.2005.851399     Document Type: Article

References (43)

1. P. Pieri, A. J. Fischman, M. Ahmad, R. H. Moore, R. J. Callahan, and H. W. Strauss, "Cardiac blood-pool scintigraphy in rats and hamsters - Comparison of 5 radiopharmaceuticals and 3 pinhole collimator apertures," J. Nucl. Med., vol. 32, no. 5, pp. 851-855, 1991.
2. D. A. Weber, M. Ivanovic, D. Franceschi, S. E. Strand, K. Erlandsson, M. Franceschi, H. L. Atkins, J. A. Coderre, H. Susskind, T. Button, and K. Ljunggren, "Einhole SPECT: An approach to in vivo high resolution SPECT imaging in small laboratory animals," J. Nucl. Med., vol. 35, no. 2, pp. 342-348, Feb. 1994.
3. R. J. Jaszczak, L. Jianying, H. Wang, M. R. Zalutsky, and R. E. Coleman, "Pinhole collimation for ultra-high-resolution, small-fleld-of-view SPECT," Phys. Med. Biol., vol. 39, no. 3, pp. 425-437, 1994.
4. K. Ishizu, T. Mukai, Y. Yonekura, M. Pagani, T. Fujita, Y. Magata, S. Nishizawa, N. Tamaki, H. Shibasaki, and J. Konishi, "Ultra-high resolution SPECT system using four pinhole collimators for small animal studies," J. Nucl. Med., vol. 36, no. 12, pp. 2282-2287, Dec. 1995.
5. F. A. Dilmanian, D. A. Weber, J. A. Coderre, D. D. Joel, K.-C. Shi, G. E. Meinken, P. Som, Y.-N. Tang, N. D. Volkow, C. Yee, A. B. Brill, M. Watanabe, E. Inuzuka, K. Oba, R. Gerson, H. Iida, and A. Hiruma, "A high-resolution SPECT system based on a microchannel-plate imager," IEEE Trans. Nucl. Sci., pt. 1, vol. 37, no. 2, pp. 687-695, Apr. 1990.
6. A. G. Weisenberger, E. Bradley, S. Majewski, and M. Saha, "Development of a novel radiation imaging detector system for in vivo gene imaging in small animal studies," in Conf. Rec. 1996 IEEE Nuclear Science Symp. Medical Imaging Conf., Anaheim, CA, Nov. 2-9, 1996, pp. 1201-1205.
7. R. Wojcik et al., "High spatial resolution gamma imaging detector based on a 5″ diameter R3292 Hamamatsu PSPMT," IEEE Trans. Nucl. Sci., vol. 45, no. 3, pp. 487-491, Jun. 1998.
8. N. Schramm, A. Wirrwar, F. Sonnenberg, and H. Halling, "Compact high resolution detector for small animal SPECT," IEEE Trans. Nucl. Sci., vol. 47, no. 3, pp. 1163-1167, Jun. 2000.
9. M. V. Green, J. Seidel, and W. R. Gandler, "A small animal system capable of PET, SPECT and planar imaging," J. Nuc. Med., vol. 35, no. 5, pp. P61-P61, 1994.
10. L. R. MacDonald, B. E. Patt, J. S. Iwanczyk, B. M. W. Tsui, Y. Wang, E. C. Frey, D. E. Wessell, P. D. Acton, and H. F. Kung, "Pinhole SPECT of mice using the LumaGEM gamma camera," IEEE Trans. Nucl. Sci., vol. 48, no. 3, pp. 830-836, Jun. 2001.
11. D. P. McElroy et al., "Performance evaluation of A-SPECT: A high resolution desktop pinhole SPECT system for imaging small animals," IEEE Trans. Nucl. Sci., vol. 49, no. 5, pp. 2139-2147, Oct. 2002.
12. S. R. Cherry, Y. Shao, R. W. Silverman, K. Meadors, S. Siegal, A. Chatziioannou, J. W. Young, W. F. Jones, J. C. Moyers, D. Newport, A. Boutefnouchet, T. H. Farquhar, M. Andreaco, M. Paulus, D. M. Binkley, and R. Nutt, "MicroPET: A high resolution PET scanner for imaging small animals," IEEE Trans. Nucl. Sci., vol. 44, no. 3, pp. 1161-1166, Jun. 1997.
13. K. Ishizu, T. Mukai, Y. Yonekura, M. Pagani, T. Fujita, Y. Magata, S. Nishizawa, N. Tamaki, H. Shibasaki, and J. Konishi, "Ultra-high resolution SPECT system using four pinhole collimators for small animal studies," J. Nucl. Med., vol. 36, no. 12, pp. 2282-2287, Dec. 1995.
14. H. I. Kornblum, D. M., A. J. Annala, K. J. Tatsukawa, M. E. Phelps, and S. R. Cherry, "In vivo imaging of neuronal activation and plasticity in the rat brain by high resolution positron emission tomography (microPET)," Nature Biotechnol., vol. 18, pp. 655-660, 2000.
15. P. D. Acton, S. Choi, K. Plössl, and H. F. Kung, "Qualification of dopamine transporters in the mouse brain using ultra-high resolution single-photon emission tomography," Eur. J. Nucl. Med., vol. 29, pp. 691-698, 2002.
16. R. S. Balaban and V. A. Hampshire, "Challenges in small animal noninvasive imaging," ILAR J., vol. 42, no. 3, pp. 248-262, 2001.
17. C. L. Woody, S. P. Stoll, D. J. Schlyer, M. Gerasimov, P. Vaska, S. Shokouhi, N. Volkow, J. S. Fowler, and S. L. Dewey, "A study of scintillation beta microprobes," in Conf. Rec. 2001 IEEE Nuclear Science Symp. Medical Imaging Conf., vol. 4, Nov. 2001, pp. 2002-2007.
18. L. Zimmer, W. Hassoun, F. Pain, F. Bonnefoi, P. Laniece, R. Mastrippolito, L. Pinot, J. F. Pujol, and V. Leviel, "SIC, an intracerebral beta (+)-range-sensitive probe for radiopharmacology investigations in small laboratory animals: Binding studies with (11)C-raclopride," J. Nucl. Med., vol. 43, no. 2, pp. 227-233, Feb. 2002.
19. P. Vaska, D. J. Schlyer, C. L. Woody, S. P. Stoll, V. Radeka, and N. Volkow, "Imaging the unanesthetized rat brain with PET: A feasibility study," in Conf. Rec. 2001 IEEE Nuclear Science Symp. Medical Imaging Conf., vol. 3, Nov. 2001, pp. 1569-1571.
20. M.J.Paulus, S.S. Gleason, S. J.Kennel,P.R.Hunsicker, and D.K.Johnson, "High resolution x-ray computed tomography: An emerging tool for small animal cancer research," Neoplasia, vol. 2, pp. 62-70, 2000.
21. M. J. Paulus, H. Sari-Sarraf, S. S. Gleason, M. Bobrek, J. S. Hicks, D. K. Johnson, J. K. Behel, L. H. Thompson, and W. C. Allen, "A new X-ray computed tomography system for laboratory mouse imaging," IEEE Trans. Nucl. Sci., vol. 46, no. 3, pp. 558-564, Jun. 1999.
22. S. S. Gleason, H. Sari-Sarraf, M. J. Paulus, D. K. Johnson, S. J. Norton, and M. A. Abidi, "Reconstruction of multi-energy, X-ray computed tomography images of laboratory mice," IEEE Trans. Nucl. Sci., vol. 46, no. 4, pp. 1081-1086, Aug. 1999.
23. E. Bradley, private communication, 2002 Biology Department, College of William and Mary, Williamsburgh, VA.
24. R. Wojcik, S. Majewski, B. Kross, V. Popov, and A. G. Weisenberger, "Optimized readout of small gamma cameras for high resolution single gamma and positron emission imaging," in Conf. Rec. 2001 IEEE Nuclear Science Symp. Medical Imaging Conf., vol. 3, Nov. 2001, pp. 1821-1825.
25. B. L. Welch, S. Majewski, V. Popov, A. G. Weisenberger, R. Wojcik, J. S. Goddard, S. S. Gleason, and M. J. Paulus, "Acquisition and control for a combined SPECT/infrared tracking system for restraint-free small animal imaging," in Conf. Rec. 2003 IEEE Nuclear Science Symp. Medical Imaging Conf., vol. 4, Oct. 2003, pp. 2310-2314.
26. R. R. Fulton, S. R. Meikle, S. Eberl, J. Pfeiffer, C. J. Constable, and M. J. Fulham, "Correction for head movements in positron emission tomography using an optical motion-tracking system," IEEE Trans. Nucl. Sci, vol. 49, no. 1, pp. 116-123, Feb. 2002.
27. P. M. Bloomfield, T. J. Spinks, J. Reed, L. Schnorr, A. M. Westrip, L. Livieratos, R. Fulton, and T. Jones, "The design and implementation of a motion correction scheme for neurological PET," Phys. Med. Biol., vol. 48, no. 8, pp. 959-978, 2003.
28. M. A. Gennert, P. P. Bruyant, M. V. Narayanan, and M. A. King, "Assessing a system to detect patient motion in SPECT imaging using stereo optical cameras," in Conf. Rec. 2001 IEEE Nuclear Science Symp. Medical Imaging Conf., vol. 3, 2003, pp. 1567-1570.
29. R. R. Fulton, S. Eberl, S. R. Meikle, B. F. Hutton, and M. Braun, "A practical 3D tomographic method for correcting patient head motion in clinical SPECT," IEEE Trans. Nucl. Sci., vol. 46, no. 3, pp. 667-672, Jun. 1999.
30. E. Gravier and Y. Yang, "Motion-compensated reconstruction of tomographic image sequences," in Proc. IEEE Int. Conf. Image Processing, vol. 2, 2003, pp. 807-810.
31. M. Ivanovic, D. A. Weber, S. Loncaric, C. Pellot-Barakat, and D. K. Shelton, "Patient motion correction for multicamera SPECT using 360° acquisition/detector," in Con. Rec. 1997 IEEE Nuclear Science Symp. Medical Imaging Conf., vol. 2, 1997, pp. 989-993.
32. A. Z. Kyme, B. F. Hutton, R. L. Hatton, D. W. Skerrett, and L. R. Barnden, "Practical aspects of a data-driven motion correction approach for brain SPECT," IEEE Trans. Med. Imag., vol. 22, no. 6, pp. 722-729, Jun. 2003.
33. J. S. Goddard, S. S. Gleason, M. J. Paulus, A. Weisenberger, M. Smith, B. Welch, and R. Wojcik, "Real-time landmark-based unrestrained animal tracking system for motion-corrected PET/SPECT imaging," in Conf. Rec. 2002 IEEE Nuclear Science Symp. Medical Imaging Conf., vol. 3, Nov. 2002, pp. 1534-1537.
34. Z. Zhang, "A flexible new technique for camera calibration," Microsoft Research, Microsoft Corp., Redmond, WA, MSR-TR-98-71, 1998.
35. D. A. Weber, M. Ivanovic, D. Franceschi, S.-E. Strand, K. Erlandsson, M. Franceschi, H. L. Atkins, J. A. Coderre, H. Susskind, T. Button, and K. Ljunggren, "Pinhole SPECT: An approach to in vivo high resolution SPECT imaging in small laboratory animals," J. Nucl. Med., vol. 35, pp. 342-348, 1994.
36. R. J. Jaszczak, J. Li, H. Wang, M. R. Zalutsky, and R. E. Coleman, "Pinhole collimation for ultra-high-resolution, small-field-of-view SPECT," Phys. Med. Biol., vol. 39, pp. 425-437, 1994.
37. M. C. Wu, H. R. Tang, D. W. Gao, A. Ido, J. W. O'Connell, B. H. Hasegawa, and M. W. Dae, "ECG-gated pinhole SPECT in mice with millimeter spatial resolution," IEEE Trans. Nucl. Sci., vol. 47, no. 3, pp. 1218-1221, Jun. 2000.
38. N. U. Schramm, G. Ebel, U. Engeland, M. Schurrat, M. Béhé, and T. M. Behr, "High resolution SPECT using multi-pinhole collimation," IEEE Trans. Nucl. Sci., pt. 2, vol. 50, no. 3, pp. 315-320, Jun. 2003.
39. S. R. Meikle, R. R. Fulton, S. Eberl, M. Dahlbom, K.-P. Wong, and M. J. Fulham, "An investigation of coded aperture imaging for small animal SPECT," IEEE Trans. Nucl. Sci., vol. 48, no. 3, pp. 816-821, Jun. 2001.
40. M. F. Smith, S. R. Meikle, S. Majewski, and A. G. Weisenberger, "Design of multipinhole collimators for small animal SPECT," in Conf. Rec. 2003 IEEE Nuclear Science Symp. Medical Imaging Conf., vol. 4, Oct. 2003, pp. 2291-2295.
41. S. R. Meikle, P. Kench, R. Wojcik, M. F. Smith, A. G. Weisenberger, S. Majewski, M. L. F. Lerch, and A. B. Rozenfeld, "Performance evaluation of a multipinhole small animal SPECT system," in Conf. Rec. 2003 IEEE Nuclear Science Symp. Medical Imaging Conf., vol. 3, Oct. 2003, pp. 1988-1992.
42. M. F. Smith, S. Majewski, S. R. Meikle, A. G. Weisenberger, V. Popov, and R. F. Wojcik, "Design of high sensitivity, high resolution compact single photon imaging devices for small animal and dedicated breast imaging," in Conf. Rec. 2001 IEEE Nuclear Science Symp. Medical Imaging Conf., vol. 3, Nov. 2002, pp. 1592-1596.
43. Laser Triangulation. [Online]. Available:http://www.ivp.se/documentation/ technology/LaserTriangulation.pdf