Long-term changes in bone mineral and biomechanical properties of vertebrae and femur in aging, dietary calcium restricted, and/or estrogen- deprived/-replaced rats

Journal of Bone and Mineral Research

Volumn 12, Issue 5, 1997, Pages 820-831

  Jiang, Yebin ^a,b,d   Zhao, Jenny ^b   Genant, Harry K ^b   Dequeker, Jan ^a   Geusens, Piet ^c  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HASSELT UNIVERSITY   (Belgium)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE MASS; BONE MINERAL; BONE MINERALIZATION; BONE STRENGTH; CALCIUM BLOOD LEVEL; CALCIUM INTAKE; DUAL ENERGY X RAY ABSORPTIOMETRY; ESTROGEN BLOOD LEVEL; ESTROGEN THERAPY; FEMALE; FEMUR SHAFT; LUMBAR SPINE; METAPHYSIS; NONHUMAN; OSTEOPOROSIS; OVARIECTOMY; QUALITY CONTROL; RAT; SOCIOECONOMICS;

EID: 0030983148     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1997.12.5.820     Document Type: Article

References (63)

1. Cummings R 1990 Calcium intake and bone mass: A quantitative review of the evidence. Calcif Tissue Int 47:194-201.
2. Recker R, Davies K, Hinders S, Heaney R, Stegman M, Kimmel D 1992 Bone gain in young adult women. JAMA 268:2403-2408.
3. 3 and calcium to prevent hip fractures in elderly women. N Engl J Med 327:1637-1642.
4. Gruber H, Gutteridge D, Baylink D 1984 Osteoporosis associated with pregnancy and lactation: Bone biopsy and skeletal features in three patients. Metab Bone Dis Rel Res 5:159-165.
5. Alevizaki C, Ikkos D, Singhelakis P 1973 Progressive decrease of true intestinal calcium absorption with age in normal man. J Nucl Med 14:760-762.
6. 3 on osteopenia induced by prednisolone in adult rats. Calcif Tissue Int 34:253-257.
7. Gruber H, Stover S 1994 Maternal and weanling bone: The influence of lowered calcium intake and maternal dietary history. Bone 15:167-176.
8. Nordin B, Horsman A, Marshall D 1979 Calcium requirements and calcium therapy. Clin Orthop 140:216-239.
9. Wronski T, Cintron M, Doherty A, Dann L 1988 Estrogen treatment prevents osteopenia and depresses bone turnover in ovariectomized rats. Endocrinology 123:681-686.
10. Kalu D 1991 The ovariectomized rat model of postmenopausal bone loss. J Bone Miner Res 15:175-192.
11. Frost H, Jee W 1992 On the rat model of human osteopenias and osteoporoses. Bone Miner 18:227-236.
12. Genant H, Cann C, Ettinger B, Gordan G 1982 Quantitative computed tomography of vertebral spongiosa: A sensitive method for detecting early bone loss after oophorectomy. Ann Intern Med 97:699-705.
13. Lindsay R, Cosman F 1992 Primary osteoporosis. In: Coe F, Favas M (ed.) Disorders of Bone and Mineral Metabolism. Raven Press, New York, NY, U.S.A., pp. 831-888.
14. 2 adds bone to a cancellous bone site with a closed growth plate and low bone turnover in ovariectomized rats. Bone 15:137-146.
15. Sogaard C, Danielsen C, Thorling E, Mosekilde L 1994 Long- term exercise of young and adult female rats: Effect on femoral neck biomechanical competence and bone structure. J Bone Miner Res 9:409-416.
16. Zernicke R, Salem G, Barnard R, Schramm E 1995 Long-term, high-fat-sucrose diet alters rat femoral neck and vertebral morphology, bone mineral content, and mechanical properties. Bone 16:25-31.
17. Peng Z, Tuukkanen J, Zhang H, Jämsä T, Väänänen H 1994 The mechanical strength of bone in different rat models of experimental osteoporosis. Bone 15:523-532.
18. Peng Z, Zuukkanen J, Väänänen H 1994 Exercise can provide protection against bone loss and prevent the decrease in mechanical strength of femoral neck in ovariectomized rats. J Bone Miner Res 9:1559-1564.
19. Li M, Wronski T 1995 Response of femoral neck to estrogen depletion and parathyroid hormone in aged rats. Bone 16:551-557.
20. Hansson T, Roos B 1981 The relation between bone mineral content, experimental compression fractures, and disc degeneration in lumbar vertebrae. Spine 6:147-153.
21. de Vernejoul M, Jiang Y, Lacheretz F, Barbier A, Geusens P, Morieux C, Pfersdorff C 1990 Prevention of bone loss following tiludronate administration to ovariectomized beagle dogs. In: Christiansen C, Overgaard K (eds.) Osteoporosis. Osteopress ApS, Copenhagen, Denmark, pp. 1119-1122.
22. Geusens P, Nijs J, Van Der Perre G, Van Audekercke R, Lowet G, Goovaerts S, Barbier A, Lacheretz F, Remandet B, Jiang Y, Dequeker J 1992 Longitudinal effect of tiludronate on bone mineral density, resonant frequency, and strength in monkeys. J Bone Miner Res 7:599-609.
23. Mosekilde L, Danielsen C, Knudsen U 1993 The effect of aging and ovariectomy on the vertebral bone mass and biomechanical properties of mature rats. Bone 14:1-6.
24. Jiang Y, Zhao J, Van Audekercke R, Dequeker J, Geusens P 1996 Effect of low-dose long-term NaF preventive treatment on rat bone mass and biomechanical properties. Calif Tissue Int 58:30-39.
25. Jiang Y 1995 Radiology and Histology in the Assessment of Bone Quality. Peeters & Jiang, Leuven, Belgium, pp. 15-132.
26. Martin R 1991 Determinants of the mechanical properties of bone. J Biomech 24:77-88.
27. American Institute of Nutrition 1980 Second report of the ad hoc committee on standards for nutritional sciences. J Nutr 110:1726.
28. Geusens P, Dequeker J, Nijs J, Verstraeten A, Bramm E 1991 Prevention and treatment of osteopenia in the ovariectomized rat: Effect of combined therapy with estrogens, 1-alpha vitamin D, and prednisolone. Calcif Tissue Int 48:127-137.
29. Martens M, Van Audekercke R, De Meester P, Mulier J 1980 The mechanical characteristics of the long bones of the lower extremity in torsional loading. J Biomech 13:667-676.
30. Augat P, Reeb H, Claes LE 1996 Prediction of fracture load at different skeletal sites by geometric properties of the cortical shell. J Bone Miner Res 11:1356-1363.
31. Conover W 1980 Practical Nonparametric Statistics. John Wiley & Sons, New York, NY, U.S.A., pp. 229-237.
32. Neter J, Wasserman W, Whitmore G 1982 Applied Statistics. Allyn and Bacon, Boston, MA, U.S.A., pp. 54-572.
33. Turner R, Vandersteenhoven J, Bell N 1987 The effects of ovariectomy and 17β-estradiol on cortical bone histomorphometry in growing rats. J Bone Miner Res 2:115-122.
34. Barenglots E, Gajardo H, Rosol T, D'Anza J, Pena M, Botsis J, Kukreja S 1990 Effects of progesteron on postovariectomy bone loss in aged rats. J Bone Miner Res 5:1143-1147.
35. Mazess R 1982 On aging bone loss. Clin Orthop 165:239-252.
36. Riggs B, Wahner H, Melton III L, Richelson L, Judd H, Offord K 1986 Rates of bone loss in the appendicular and axial skeletons of women: Evidence of substantial vertebral bone loss before menopause. J Clin Invest 77:1487-1491.
37. Cummings S, Kelsey J, Nevitt M, O'Dowd K 1985 Epidemiology of osteoporosis and osteoporotic fractures. Epidemiol Rev 7:178-208.
38. Riggs B, Melton III L 1986 Involutional osteoporosis. N Engl J Med 314:1676-1684.
39. Wronski T, Dann L, Horner S 1989 Time course of vertebral osteopenia in ovariectomized rats. Bone 10:295-301.
40. Wronski T, Schenk P, Cintron M, Walsh C 1987 Effect of body weight in osteopenia in ovariectomized rats. Calcif Tissue Int 40:155-159.
41. Demetropoulos C, Willis C, Goldstein S 1993 Biomechanical characteristics of rat trabecular bone. Trans Orthop Res Soc 18:585.
42. Harrigan T, Jasty M, Mann R, Harris W 1988 Limitations of the continuum assumption in cancellous bone. J Biomech 21:269-275.
43. Turner C, Burr D 1993 Basic biomechanical measurements of bone: A tutorial. Bone 14:595-608.
44. Einhorn T 1992 Bone strength: The bottom line. Calcif Tissue Int 51:333-339.
45. Smith R, Jr, Walker R 1964 Femoral expansion in aging women: Implications for osteoporosis and fractures. Science 145:156-157.
46. Beck T, Ruff C, Scott Jr W, Plato C, Tobin J, Quan C 1992 Sex differences in geometry of the femoral neck with aging: A structural analysis of bone mineral data. Calcif Tissue Int 50:24-29.
47. Tran Van P, Vignery A, Baron R 1982 Cellular kinetics of the bone remodeling requence in the rat. Anat Rec 202:445-451.
48. Baron R, Tross R, Vignery A 1984 Evidence of sequential remodeling in rat trabecular bone: Morphology, dynamic histomorphometry, and changes in ovariectomized rats. Endocrinology 115:507-512.
49. 2 enhances cortical bone mass and activates intracortical bone remodeling in intact and ovariectomized female rats. Bone 11:253-266.
50. Geusens P, Schot L, Nijs J, Dequeker J 1991 Calcium-deficient diet in ovariectomized dogs limits the effect of 17β-estradiol and nandrolone decanoate on bone. J Bone Miner Res 6:791-797.
51. Shen V, Birchman R, Xu R, Lindsay R, Dempster D 1995 Short-term changes in histomophometric and biochemical turnover markers and bone mineral density in estrogen-and/or dietary calcium-deficient rats. Bone 16:149-156.
52. Aloia JF, Cohn SH, Vaswani A, Yeh JK, Yuen K, Ellis K 1985 Risk factors for postmenopausal osteoporosis. Am J Med 78:95-100.
53. Harris S, Dallal G, Dawson-Hughes B 1992 Influence of body weight on rates of change in bone density of the spine, hip, and radius in postmenopausal women. Calcif Tissue Int 50:19-23.
54. Anderson J, Garner S, Mar M, Boass A, Toverud S, Parikh I 1990 The ovariectomized, lactating rat as an experiment model for osteopenia: Calcium metabolism and bone changes. J Bone Miner Res 11:43-53.
55. Mazess R 1990 Fracture risk: A role for compact bone. Calcif Tissue Int 47:191-193.
56. Trozilli P, Takebe K, Burstein A, Zika J, Keiple K 1982 The material properties of immature bone. J Biomech Eng 104:12-20.
57. Keller T, Spengler D, Carter D 1986 Geometric, elastic, and structural properties of maturing rat femora. J Orthop Res 4:57-67.
58. Aerssens J, Van Audekercke R, Geusens P, Schot LPC, Osman AAH, Dequeker J 1993 Mechanical properties, bone mineral content, and bone composition (collagen, ostecalcin, IGF-I) of the rat femur: Influence of ovariectomy and nandrolone decanoate (anabolic steroid) treatment. Calcif Tissue Int 53:269-277.
59. Burstein A, Zika J, Heiple K, Klein L 1975 Contribution of collagen and mineral to the elastic-plastic properties of bone. J Bone Joint Surg 57A:956-961.
60. Yamauchi H, Kushida K, Yamazaki K, Inoue T 1995 Assessment of spine bone mineral density in ovariectomized rats using DXA. J Bone Miner Res 10:1033-1039.
61. Lu PW, Briody JN, Howman-Giles R, Trube A, Cowell CT 1994 DXA for bone density measurement in small rats weighing 150-250 grams. Bone 15:199-202.
62. Casez JP, Muehlbauer RC, Lippuner K, Kelly T, Fleisch H, Jaeger P 1994 Dual-energy X-ray absorptiometry for measuring total bone mineral content in the rat: Study of accuracy and precision. Bone Miner 26:61-68.
63. Frost 1990 Structural adaptations to mechanical usage (SATMU): 1. Redefining Wolff's law: the bone modeling problem. Ana Rec 226:403-413.