Inhibitory receptors CD85j, LAIR-1, and CD152 down-regulate immunoglobulin and cytokine production by human B lymphocytes

Clinical and Diagnostic Laboratory Immunology

Volumn 12, Issue 6, 2005, Pages 705-712

  Merlo, Andrea ^a   Tenca, Claudya ^a   Fais, Franco ^a   Battini, Lorenzo ^a   Ciccone, Ermanno ^a   Grossi, Carlo E ^a   Saverino, Daniele ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD23 ANTIGEN; CD4 ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; CYTOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 8; LEUKOCYTE ASSOCIATED IMMUNOGLOBULIN LIKE RECEPTOR 1; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; CROSS LINKING; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOGLOBULIN PRODUCTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; WESTERN BLOTTING;

ANTIBODIES; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CELL LINE; CELLS, CULTURED; DOWN-REGULATION; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN-10; INTERLEUKIN-4; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; LYMPHOCYTE COOPERATION; RECEPTORS, IMMUNOLOGIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 23844483169     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/CDLI.12.6.705-712.2005     Document Type: Article

References (34)

1. Alter, A., M. Duddy, S. Hebert, K. Biernacki, A. Prat, J. P. Antel, V. W. Yong, R. K. Nuttall, C. J. Pennington, D. R. Edwards, and A. Bar-Or. 2003. Determinants of human B cell migration across brain endothelial cells. J. Immunol. 170:4497-4505.
2. Binstadt, B. A., K. M. Brumbaugh, C. J. Dick, A. M. Scharenberg, B. L. Williams, M. Colonna, L. L. Lanier, J. P. Kinet, R. T. Abraham, and P. J. Leibson. 1996. Sequential involvement of Lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation. Immunity 6:629-638.
3. Borges, L., M. L. Hsu, N. Fanger, M. Kubin, and D. Cosman. 1997. A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. J. Immunol. 159:5192-5196.
4. Brunner, M. C., C. A. Chambers, F. K. Chan, J. Hanke, A. Winoto, and J. P. Allison. 1999. CTLA-4-mediated inhibition of early events of T cell proliferation. J. Immunol. 162:5813-5820.
5. Caux, C., C. Massacrier, B. Vanbervliet, C. Barthelemy, Y. J. Liu, and J. Banchereau. 1994. Interleukin 10 inhibits T cell alloreaction induced by human dendritic cells. Int. Immunol. 6:1177-1185.
6. Colonna, M., F. Navarro, T. Bellon, M. Llano, P. Garcia, J. Samaridis, L. Angman, M. Cella, and M. Lopez-Botet. 1997. A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J. Exp. Med. 186:1809-1818.
7. Colonna, M., J. Samaridis, M. Cella, L. Angman, R. L. Allen, C. A. O'Callaghan, R. Dunbar, G. S. Ogg, V. Cerundolo, and A. Rolink. 1998. Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules. J. Immunol. 160:3096-3100.
8. Cosman, D., N. Fanger, and L. Borges. 1999. Human cytomegalovirus, MHC class I and inhibitory signalling receptors: more questions than answers. Immunol. Rev. 168:177-185.
9. Cosman, D., N. Fanger, L. Borges, M. Kubin, W. Chin, L. Peterson, and M. L. Hsu. 1997. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity 7:273-282.
10. de Waal Malefyt, R., J. Abrams, B. Bennett, C. G. Figdor, and J. E. de Vries. 1991. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174:1209-1220.
11. Dietrich, J., M. Cella, and M. Colonna. 2001. Ig-like transcript 2 (ILT2)/leukocyte Ig-like receptor 1 (LIR1) inhibits TCR signaling and actin cytoskeleton reorganization. J. Immunol. 166:2514-2521.
12. Go, N. F., B. E. Castle, R. Barrett, R. Kastelein, W. Dang, T. R. Mosmann, K. W. Moore, and M. Howard. 1990. Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. J. Exp. Med. 172:1625-1631.
13. Jeppson, J. D., H. R. Patel, N. Sakata, J. Domenico, N. Terada, and E. W. Gelfand. 1998. Requirement for dual signals by anti-CD40 and IL-4 for the induction of nuclear factor-κB, IL-6, and IgE in human B lymphocytes. J. Immunol. 161:1738-1742.
14. Jung, T., U. Schauer, C. Heusser, C. Neumann, and C. Rieger. 1993. Detection of intracellular cytokines by flow cytometry. J. Immunol. Methods 159:197-207.
15. Kuiper, H. M., M. Brouwer, P. S. Linsley, and R. A. van Lier. 1995. Activated T cells can induce high levels of CTLA-4 expression on B cells. J. Immunol. 155:1776-1783.
16. + T-cell clones specific for Mycobacterium tuberculosis. Infect. Immun. 69:6022-6029.
17. Meyaard, L., G. J. Adema, C. Chang, E. Woollatt, G. R. Sutherland, L. L. Lanier, and J. H. Phillips. 1997. LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes. Immunity 7:283-290.
18. Nielsen, L. S., J. Frydenberg, M. Lind, M. Deleuran, K. Stengaard-Pedersen, and B. Deleuran. 1997. CD19-selected B lymphocytes synthesize, secrete and migrate in the presence of IL-8. TNF-α and γIP-10 are also B lymphocyte migratory factors. Cytokine 9:747-753.
19. Oosterwegel, M. A., R. J. Greenwald, D. A. Mandelbrot, R. B. Lorsbach, and A. H. Sharpe. 1999. CTLA-4 and T cell activation. Curr. Opin. Immunol. 11:294-300.
20. Peguet-Navarro, J., C. Moulon, C. Caux, C. Dalbiez-Gauthier, J. Banchereau, and D. Schmitt. 1994. Interleukin-10 inhibits the primary allogeneic T cell response to human epidermal Langerhans cells. Eur. J. Immunol. 24:884-891.
21. Pioli, C., L. Gatta, V. Ubaldi, and G. Doria. 2000. Inhibition of IgG1 and IgE production by stimulation of the B cell CTLA-4 receptor. J. Immunol. 165:5530-5536.
22. Poggi, A., E. Tomasello, E. Ferrero, M. R. Zocchi, and L. Moretta. 1998. p40/LAIR-1 regulates the differentiation of peripheral blood precursors to dendritic cells induced by granulocyte-monocyte colony-stimulating factor. Eur. J. Immunol. 28:2086-2091.
23. Raiter, A., A. Novogrodsky, and B. Hardy. 1999. Activation of lymphocytes by BAT and anti CTLA-4: comparison of binding to T and B cells. Immunol. Lett. 69:247-251.
24. Rousset, F., E. Garcia, T. Defrance, C. Peronne, N. Vezzio, D. H. Hsu, R. Kastelein, K. W. Moore, and J. Banchereau. 1992. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad. Sci. USA 89:1890-1893.
25. Saeland, S., V. Duvert, I. Moreau, and J. Banchereau. 1993. Human B cell precursors proliferate and express CD23 after CD40 ligation. J. Exp. Med. 178:113-120.
26. Saverino, D., M. Fabbi, F. Ghiotto, A. Merlo, S. Bruno, D. Zarcone, C. Tenca, M. Tiso, G. Santoro, G. Anastasi, D. Cosman, C. E. Grossi, and E. Ciccone. 2000. The CD85/LIR-1/ILT2 inhibitory receptor is expressed by all human T lymphocytes and down-regulates their functions. J. Immunol. 165:3742-3755.
27. Saverino, D., M. Fabbi, A. Merlo, G. Ravera, C. E. Grossi, and E. Ciccone. 2002. Surface density expression of the leukocyte-associated Ig-like receptor-1 is directly related to inhibition of human T-cell functions. Hum. Immunol. 63:534-546.
28. Saverino, D., A. Merlo, S. Bruno, V. Pistoia, C. E. Grossi, and E. Ciccone. 2002. Dual effect of CD85/leukocyte Ig-like receptor-1/Ig-like transcript 2 and CD152 (CTLA-4) on cytokine production by antigen-stimulated human T cells. J. Immunol. 168:207-215.
29. Schratzberger, P., S. Dunzendorfer, N. Reinisch, C. M. Kahler, and C. J. Wiedermann. 1997. Interleukin-8-induced human peripheral blood B-lymphocyte chemotaxis in vitro. Immunol. Lett. 58:167-170.
30. Tinnell, S. B., S. M. Jacobs-Helber, E. Sterneck, S. T. Sawyer, and D. H. Conrad. 1998. STAT6, NF-κB and C/EBP in CD23 expression and IgE production. Int. Immunol. 10:1529-1538.
31. van der Vuurst de Vries, A. R., H. Clevers, T. Logtenberg, and L. Meyaard. 1999. Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is differentially expressed during human B cell differentiation and inhibits B cell receptor-mediated signaling. Eur. J. Immunol. 29:3160-3167.
32. Victor, F. C., and A. B. Gottlieb. 2002. TNF-alpha and apoptosis: implications for the pathogenesis and treatment of psoriasis. J. Drugs Dermatol. 1:264-275.
33. Xerri, L., E. Devilard, J. Hassoun, D. Olive, and F. Birg. 1997. In vivo expression of the CTLA4 inhibitory receptor in malignant and reactive cells from human lymphomas. J. Pathol. 183:182-187.
34. Yoshida, K., M. Matsuoka, S. Usuda, A. Mori, K. Ishizaka, and H. Sakano. 1990. Immunoglobulin switch circular DNA in the mouse infected with Nippostrongylus brasiliensis: evidence for successive class switching from μ to ε via γ1. Proc. Natl. Acad. Sci. USA 87:7829-7833.