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Volumn 18, Issue 3, 2005, Pages 144-161

Investigation of multidrug resistance in cultured human renal cell carcinoma cells by 31P-NMR spectroscopy and treatment survival assays

Author keywords

31P NMR spectroscopy; Metabolomics; Multidrug resistance; P glycoprotein; Renal cell carcinoma

Indexed keywords

ALPHA INTERFERON; CALCIUM ANTAGONIST; CREATINE PHOSPHATE; DILTIAZEM; GLYCEROPHOSPHOETHANOLAMINE; GLYCEROPHOSPHORYLCHOLINE; PHOSPHATE; PHOSPHORYLCHOLINE; RECOMBINANT ALPHA2B INTERFERON; VINBLASTINE; VINBLASTINE SULFATE;

EID: 23844480008     PISSN: 09685243     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10334-005-0107-7     Document Type: Article
Times cited : (12)

References (80)
  • 2
    • 0033090414 scopus 로고    scopus 로고
    • The problematic nature of metastasized renal cell carcinoma
    • Bichler K-H, Wechsel HW (1999) The problematic nature of metastasized renal cell carcinoma. Anticancer Res 19:1463-1466
    • (1999) Anticancer Res , vol.19 , pp. 1463-1466
    • Bichler, K.-H.1    Wechsel, H.W.2
  • 3
    • 0025122325 scopus 로고
    • Detection of drug resistance and P-glycoprotein in human renal cell carcinomas
    • Bak M, Efferth T, Mickisch G, Mattern J, Volm M (1990) Detection of drug resistance and P-glycoprotein in human renal cell carcinomas. Eur Urol 17:72-75
    • (1990) Eur Urol , vol.17 , pp. 72-75
    • Bak, M.1    Efferth, T.2    Mickisch, G.3    Mattern, J.4    Volm, M.5
  • 4
    • 0023882866 scopus 로고
    • Measurement of multidrug-resistance messenger RNA in urogenital cancers; elevated expression in renal cell carcinoma is associated with intrinsic drug resistance
    • Kakehi Y, Kanamaru H, Yoshida O, Ohkubo H, Nakanishi S, Gottesman MM, Pastan I (1988) Measurement of multidrug-resistance messenger RNA in urogenital cancers; elevated expression in renal cell carcinoma is associated with intrinsic drug resistance. J Urol 139:862-865
    • (1988) J Urol , vol.139 , pp. 862-865
    • Kakehi, Y.1    Kanamaru, H.2    Yoshida, O.3    Ohkubo, H.4    Nakanishi, S.5    Gottesman, M.M.6    Pastan, I.7
  • 5
    • 0024391129 scopus 로고
    • Multidrug resistance: P-glycoprotein and its allies-the elusive foes
    • Chabner BA, Fojo A (1989) Multidrug resistance: P-glycoprotein and its allies-the elusive foes. J Natl Cancer Inst 81:910-913
    • (1989) J Natl Cancer Inst , vol.81 , pp. 910-913
    • Chabner, B.A.1    Fojo, A.2
  • 6
    • 0027285568 scopus 로고
    • Current status and future directions of research on multidrug resistance. The impact of contemporary biotechnology
    • Mickisch GH (1993) Current status and future directions of research on multidrug resistance. The impact of contemporary biotechnology. Urol Res 21:79-81
    • (1993) Urol Res , vol.21 , pp. 79-81
    • Mickisch, G.H.1
  • 7
    • 0024398797 scopus 로고
    • Multidrug resistance: Molecular biology and clinical relevance
    • Rothenberg M, Ling V (1989) Multidrug resistance: molecular biology and clinical relevance. J Natl Cancer Inst 81:907-910
    • (1989) J Natl Cancer Inst , vol.81 , pp. 907-910
    • Rothenberg, M.1    Ling, V.2
  • 8
    • 0024584440 scopus 로고
    • Competitive inhibition by verapamil of ATP-dependent high affinity vincristine binding to the plasma membrane of multidrug-resistant K562 cells without calcium ion involvement
    • Naito M, Tsuruo T (1989) Competitive inhibition by verapamil of ATP-dependent high affinity vincristine binding to the plasma membrane of multidrug-resistant K562 cells without calcium ion involvement. Cancer Res 49:1452-1455
    • (1989) Cancer Res , vol.49 , pp. 1452-1455
    • Naito, M.1    Tsuruo, T.2
  • 9
    • 0002140454 scopus 로고
    • The multidrug resistance gene (MDR1) represents a potential target for reversing drug resistance in human malignancies
    • Dalton WS, Sikic BI (1994) The multidrug resistance gene (MDR1) represents a potential target for reversing drug resistance in human malignancies. J NIH Res 6:54-58
    • (1994) J NIH Res , vol.6 , pp. 54-58
    • Dalton, W.S.1    Sikic, B.I.2
  • 11
    • 0007630205 scopus 로고
    • ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells
    • Horio M, Gottesman MM, Pastan I (1988) ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells. Proc Natl Acad Sci USA 85:3580-3584
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 3580-3584
    • Horio, M.1    Gottesman, M.M.2    Pastan, I.3
  • 12
    • 0025074024 scopus 로고
    • Mechanisms and modulation of multidrug resistance in primary human renal cell carcinoma
    • Mickisch GH, Roehrich K, Koessig J, Forster S, Tschada RK, Alken PM (1990) Mechanisms and modulation of multidrug resistance in primary human renal cell carcinoma. J Urol 144:755-759
    • (1990) J Urol , vol.144 , pp. 755-759
    • Mickisch, G.H.1    Roehrich, K.2    Koessig, J.3    Forster, S.4    Tschada, R.K.5    Alken, P.M.6
  • 13
    • 0031635486 scopus 로고    scopus 로고
    • Development of novel reversal agents, imidazothiazole derivatives, targeting MDR1-and MRP-mediated multidrug resistance
    • Naito S, Koike K, Ono M, Machida T, Tasaka S, Kiue A, Koga H, Kumazawa J (1998) Development of novel reversal agents, imidazothiazole derivatives, targeting MDR1-and MRP-mediated multidrug resistance. Oncology Res 10:123-132
    • (1998) Oncology Res , vol.10 , pp. 123-132
    • Naito, S.1    Koike, K.2    Ono, M.3    Machida, T.4    Tasaka, S.5    Kiue, A.6    Koga, H.7    Kumazawa, J.8
  • 14
    • 0033250545 scopus 로고    scopus 로고
    • Multidrug-resistance transporters
    • Amidon GL, Sadee W (eds) Kluwer Academic/Plenum Publishers, New York
    • Silverman JA (1999) Multidrug-resistance transporters: In: Amidon GL, Sadee W (eds) Membrane transporters as drug targets, vol 12. Kluwer Academic/Plenum Publishers, New York, pp 353-386
    • (1999) Membrane Transporters As Drug Targets , vol.12 , pp. 353-386
    • Silverman, J.A.1
  • 15
    • 0031949071 scopus 로고    scopus 로고
    • P-glycoprotein functions and substrates: Possible roles of MDR1 gene in the kidney
    • Ernest S, Bello-Reuss E (1998) P-glycoprotein functions and substrates: Possible roles of MDR1 gene in the kidney. Kidney Int 53:S11-S17
    • (1998) Kidney Int , vol.53
    • Ernest, S.1    Bello-Reuss, E.2
  • 17
    • 0007544439 scopus 로고    scopus 로고
    • MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine
    • Van Helvoort A, Smith AJ, Sprang H, Fritzsche I, Schinkel AH, Borst P, Van Meer G (1996) MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine. Cell 87:507-517
    • (1996) Cell , vol.87 , pp. 507-517
    • Van Helvoort, A.1    Smith, A.J.2    Sprang, H.3    Fritzsche, I.4    Schinkel, A.H.5    Borst, P.6    Van Meer, G.7
  • 18
    • 0344393732 scopus 로고    scopus 로고
    • Strategies for reversing drug resistance
    • Fojo T, Bates S (2003) Strategies for reversing drug resistance. Oncogene 22:7512-7523
    • (2003) Oncogene , vol.22 , pp. 7512-7523
    • Fojo, T.1    Bates, S.2
  • 19
    • 0026922513 scopus 로고
    • Studies of human tumors by MRS: A review
    • Negendank WG (1992) Studies of human tumors by MRS: A review. NMR Biomed 5:303-324
    • (1992) NMR Biomed , vol.5 , pp. 303-324
    • Negendank, W.G.1
  • 21
    • 0029684010 scopus 로고    scopus 로고
    • Proton nuclear magnetic resonance spectroscopy reveals cellular lipids involved in resistance to adriamycine and taxol by the K562 leukemia cell line
    • Le Moyec L, Tatoud R, Degeorges A, Calabresse C, Bauza G, Eugène M, Calvo F (1996) Proton nuclear magnetic resonance spectroscopy reveals cellular lipids involved in resistance to adriamycine and taxol by the K562 leukemia cell line. Cancer Res 56:3461-3467
    • (1996) Cancer Res , vol.56 , pp. 3461-3467
    • Le Moyec, L.1    Tatoud, R.2    Degeorges, A.3    Calabresse, C.4    Bauza, G.5    Eugène, M.6    Calvo, F.7
  • 22
    • 0034016548 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy of cellular lipid extracts from sensitive, resistent and reverting K562 cells and flow cytometry for investigating the P-glycoprotein function in resistance reversion
    • Le Moyec L, Legrand O, Larue V, Kawakami M, Marie J-P, Calvo F, Hantz E, Taillandier E (2000) Magnetic resonance spectroscopy of cellular lipid extracts from sensitive, resistent and reverting K562 cells and flow cytometry for investigating the P-glycoprotein function in resistance reversion. NMR Biomed 13:92-101
    • (2000) NMR Biomed , vol.13 , pp. 92-101
    • Le Moyec, L.1    Legrand, O.2    Larue, V.3    Kawakami, M.4    Marie, J.-P.5    Calvo, F.6    Hantz, E.7    Taillandier, E.8
  • 23
    • 0035569155 scopus 로고    scopus 로고
    • Differentiation of the P-gp and MRP1 multidrug resistance systems by mobile lipid 1H-NMR spectroscopy and phosphatidylserine externalization
    • Mannechez A, Collet B, Payen L, Lecureur V, Fardel O, Le Moyec L, De Certaines J-D, Leray G (2001) Differentiation of the P-gp and MRP1 multidrug resistance systems by mobile lipid 1H-NMR spectroscopy and phosphatidylserine externalization. Anticancer Res 21:3915-3920
    • (2001) Anticancer Res , vol.21 , pp. 3915-3920
    • Mannechez, A.1    Collet, B.2    Payen, L.3    Lecureur, V.4    Fardel, O.5    Le Moyec, L.6    De Certaines, J.-D.7    Leray, G.8
  • 25
    • 0031843774 scopus 로고    scopus 로고
    • Characterization of multidrug resistance and monitoring of tumor response by combined 31P and 1H nuclear magnetic resonance spectroscopic analysis
    • Venkatesan PV, Saravanan K, Nagarajan B (1998) Characterization of multidrug resistance and monitoring of tumor response by combined 31P and 1H nuclear magnetic resonance spectroscopic analysis. Anti-Cancer Drugs 9:449-456
    • (1998) Anti-Cancer Drugs , vol.9 , pp. 449-456
    • Venkatesan, P.V.1    Saravanan, K.2    Nagarajan, B.3
  • 26
    • 0031048152 scopus 로고    scopus 로고
    • Comparison of action of the anti-neoplastic drug Ionidamine on drug-sensitive and drug-resistant human breast cancer cells: 31P and 13C nuclear magnetic resonance studies
    • Vivi A, Tassini M, Ben-Horin H, Navon G, Kaplan O (1997) Comparison of action of the anti-neoplastic drug Ionidamine on drug-sensitive and drug-resistant human breast cancer cells: 31P and 13C nuclear magnetic resonance studies. Breast Cancer Res Treat 43:15-25
    • (1997) Breast Cancer Res Treat , vol.43 , pp. 15-25
    • Vivi, A.1    Tassini, M.2    Ben-Horin, H.3    Navon, G.4    Kaplan, O.5
  • 28
    • 0027255333 scopus 로고
    • Reversal of inherent multidrug-resistance in primary human renal cell carcinoma cell cultures by S 9788
    • Efferth T, Dunn TA, Berlion M, Langenbahn H, Pommerenke EW, Volm M (1993) Reversal of inherent multidrug-resistance in primary human renal cell carcinoma cell cultures by S 9788. Anticancer Res 13:905-908
    • (1993) Anticancer Res , vol.13 , pp. 905-908
    • Efferth, T.1    Dunn, T.A.2    Berlion, M.3    Langenbahn, H.4    Pommerenke, E.W.5    Volm, M.6
  • 29
    • 0025153919 scopus 로고
    • Correlations between natural resistance to doxorubicin, proliferative activity, and expression of P-glycoprotein 170 in human kidney tumor cell lines
    • Efferth T, Lohrke H, Volm M (1990) Correlations between natural resistance to doxorubicin, proliferative activity, and expression of P-glycoprotein 170 in human kidney tumor cell lines. Urol Res 18:309-312
    • (1990) Urol Res , vol.18 , pp. 309-312
    • Efferth, T.1    Lohrke, H.2    Volm, M.3
  • 30
    • 0024797947 scopus 로고
    • Reciprocal correlation between expression of P-glycoprotein and accumulation of rhodamine 123 in human tumors
    • Efferth T, Lohrke H, Volm M (1989) Reciprocal correlation between expression of P-glycoprotein and accumulation of rhodamine 123 in human tumors. Anticancer Res 9:1633-1637
    • (1989) Anticancer Res , vol.9 , pp. 1633-1637
    • Efferth, T.1    Lohrke, H.2    Volm, M.3
  • 31
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosman T (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosman, T.1
  • 32
    • 0032587428 scopus 로고    scopus 로고
    • Interferon alpha2b differentially affects proliferation of two human renal cell carcinoma cell lines differing in the P-glycoprotein-associated multidrug-resistant phenotype
    • Frank MH, Pomer S (1999) Interferon alpha2b differentially affects proliferation of two human renal cell carcinoma cell lines differing in the P-glycoprotein-associated multidrug-resistant phenotype. J Cancer Res Clin Oncol 125:117-120
    • (1999) J Cancer Res Clin Oncol , vol.125 , pp. 117-120
    • Frank, M.H.1    Pomer, S.2
  • 33
    • 0029666214 scopus 로고    scopus 로고
    • 31P MRS of human tumor cells: Effects of culture media and conditions on phospholipid metabolite concentrations
    • Franks SE, Kuesel AC, Lutz NW, Hull WE (1996) 31P MRS of human tumor cells: Effects of culture media and conditions on phospholipid metabolite concentrations. Anticancer Res 16:1365-1374
    • (1996) Anticancer Res , vol.16 , pp. 1365-1374
    • Franks, S.E.1    Kuesel, A.C.2    Lutz, N.W.3    Hull, W.E.4
  • 35
    • 0027633559 scopus 로고
    • The influence of medium formulation on phosphomonoester and UDP-hexose levels in cultured human colon tumor cells as observed by 31P NMR spectroscopy
    • Shedd SF, Lutz NW, Hull WE (1993) The influence of medium formulation on phosphomonoester and UDP-hexose levels in cultured human colon tumor cells as observed by 31P NMR spectroscopy. NMR Biomed 6:254-263
    • (1993) NMR Biomed , vol.6 , pp. 254-263
    • Shedd, S.F.1    Lutz, N.W.2    Hull, W.E.3
  • 36
    • 0027339139 scopus 로고
    • A 1H NMR method for determining temperature in cell culture perfusion systems
    • Lutz NW, Kuesel AC, Hull WE (1993) A 1H NMR method for determining temperature in cell culture perfusion systems. Magn Reson Med 29:113-118
    • (1993) Magn Reson Med , vol.29 , pp. 113-118
    • Lutz, N.W.1    Kuesel, A.C.2    Hull, W.E.3
  • 37
    • 0025408610 scopus 로고
    • 31P NMR studies of cultured human tumor cells Influence of pH on phospholipid metabolite levels and the detection of cytidine 5′-diphosphate choline
    • Kuesel AC, Graschew G, Hull WE, Lorenz W, Thielmann HW (1990) 31P NMR studies of cultured human tumor cells Influence of pH on phospholipid metabolite levels and the detection of cytidine 5′-diphosphate choline. NMR Biomed 3:78-89
    • (1990) NMR Biomed , vol.3 , pp. 78-89
    • Kuesel, A.C.1    Graschew, G.2    Hull, W.E.3    Lorenz, W.4    Thielmann, H.W.5
  • 38
    • 0023821418 scopus 로고
    • 31P nuclear magnetic resonance spectroscopy studies of tumor energy metabolism and its relationship to intracapillary oxyhemoglobin saturation status and tumor hypoxia
    • Rofstad EK, DeMuth P, Fenton BM, Sutherland RM (1988) 31P nuclear magnetic resonance spectroscopy studies of tumor energy metabolism and its relationship to intracapillary oxyhemoglobin saturation status and tumor hypoxia. Cancer Res 48:5440-5446
    • (1988) Cancer Res , vol.48 , pp. 5440-5446
    • Rofstad, E.K.1    DeMuth, P.2    Fenton, B.M.3    Sutherland, R.M.4
  • 40
    • 33645341974 scopus 로고    scopus 로고
    • SAS Institute, Cary
    • StatView (1999) Reference book. SAS Institute, Cary
    • (1999) Reference Book
  • 41
    • 0038009220 scopus 로고    scopus 로고
    • Immuntherapie des metastasierenden Nierenzellkarzinoms in Deutschland
    • Huland E, Heinzer H, Timm S, Aalamian M, Huland H (2002) Immuntherapie des metastasierenden Nierenzellkarzinoms in Deutschland. Urologe (A) 41:282-287
    • (2002) Urologe (A) , vol.41 , pp. 282-287
    • Huland, E.1    Heinzer, H.2    Timm, S.3    Aalamian, M.4    Huland, H.5
  • 42
    • 0028816835 scopus 로고
    • Induction of insulin antibodies and insulin allergy under alpha-interferon treatment of renal cell carcinoma in a patient with insulin-treated diabetes mellitus - A case report
    • Krug J, Fritzsch J, Aust G (1995) Induction of insulin antibodies and insulin allergy under alpha-interferon treatment of renal cell carcinoma in a patient with insulin-treated diabetes mellitus - a case report. Int Arch Allergy Immunol 106:169-172
    • (1995) Int Arch Allergy Immunol , vol.106 , pp. 169-172
    • Krug, J.1    Fritzsch, J.2    Aust, G.3
  • 43
    • 0033371680 scopus 로고    scopus 로고
    • Tumour phospholipid metabolism
    • Podo F (1999) Tumour phospholipid metabolism. NMR Biomed 12:413-439
    • (1999) NMR Biomed , vol.12 , pp. 413-439
    • Podo, F.1
  • 44
    • 0032586984 scopus 로고    scopus 로고
    • Using the beta/alpha peak-height ratio of ATP in 31P spectra to measure free [Mg2+]: Theoretical and practical problems
    • Mulquiney PJ, Kuchel PW (1999) Using the beta/alpha peak-height ratio of ATP in 31P spectra to measure free [Mg2+]: theoretical and practical problems. NMR Biomed 12:217-220
    • (1999) NMR Biomed , vol.12 , pp. 217-220
    • Mulquiney, P.J.1    Kuchel, P.W.2
  • 45
    • 0037147246 scopus 로고    scopus 로고
    • Simultaneous determination of low free Mg2+ and pH in human sickle cells using 31P NMR spectroscopy
    • Willcocks JP, Mulquiney PJ, Ellory JC, Veech RL, Radda GK, Clarke K (2002) Simultaneous determination of low free Mg2+ and pH in human sickle cells using 31P NMR spectroscopy. J Biol Chem 277:49911-49920
    • (2002) J Biol Chem , vol.277 , pp. 49911-49920
    • Willcocks, J.P.1    Mulquiney, P.J.2    Ellory, J.C.3    Veech, R.L.4    Radda, G.K.5    Clarke, K.6
  • 47
    • 0028176723 scopus 로고
    • Effect of alpha-interferon on P-glycoprotein expression and function and on verapamil modulation of doxorubicin resistance
    • Kang Y, Perry RR (1994) Effect of alpha-interferon on P-glycoprotein expression and function and on verapamil modulation of doxorubicin resistance. Cancer Res 54:2952-2958
    • (1994) Cancer Res , vol.54 , pp. 2952-2958
    • Kang, Y.1    Perry, R.R.2
  • 48
    • 0034779860 scopus 로고    scopus 로고
    • Interferon-alpha 2b modulation of doxorubicin sensitivity in a multidrug resistant cell line
    • Lucero Gritti MF, Beviacqua M, Bordenave RH, Rumi LS (2001) Interferon-alpha 2b modulation of doxorubicin sensitivity in a multidrug resistant cell line. J Exp Clin Res 20:393-400
    • (2001) J Exp Clin Res , vol.20 , pp. 393-400
    • Lucero Gritti, M.F.1    Beviacqua, M.2    Bordenave, R.H.3    Rumi, L.S.4
  • 49
    • 0031400690 scopus 로고    scopus 로고
    • Is the expression of multidrug resistance gene product a prognostic indicator for the clinical outcome of patients with renal cancer?
    • Hofmockel G, Bassukas ID, Wittmann A, Dammrich J (1997) Is the expression of multidrug resistance gene product a prognostic indicator for the clinical outcome of patients with renal cancer? Br J Urol 80:11-17
    • (1997) Br J Urol , vol.80 , pp. 11-17
    • Hofmockel, G.1    Bassukas, I.D.2    Wittmann, A.3    Dammrich, J.4
  • 50
    • 0036244343 scopus 로고    scopus 로고
    • Expression of genes involved in chemoresistance, proliferation and apoptosis in clinical samples of renal cell carcinoma and correlation with clinical outcome
    • Oudard S, Levalois C, Andrieu JM, Bougaran J, Validire P, Thiounn N, Poupon MF, Fourme E, Chevillard S (2002) Expression of genes involved in chemoresistance, proliferation and apoptosis in clinical samples of renal cell carcinoma and correlation with clinical outcome. Anticancer Res 22:121-128
    • (2002) Anticancer Res , vol.22 , pp. 121-128
    • Oudard, S.1    Levalois, C.2    Andrieu, J.M.3    Bougaran, J.4    Validire, P.5    Thiounn, N.6    Poupon, M.F.7    Fourme, E.8    Chevillard, S.9
  • 51
    • 0038580154 scopus 로고    scopus 로고
    • Reversal of MDR in solid tumors
    • Gupta S, Tsuruo T (eds) Wiley, Chichester
    • Giaccone G, Pinedo HM (1996) Reversal of MDR in solid tumors: In: Gupta S, Tsuruo T (eds) Multidrug resistance in cancer cells. Wiley, Chichester, pp 473-491
    • (1996) Multidrug Resistance in Cancer Cells , pp. 473-491
    • Giaccone, G.1    Pinedo, H.M.2
  • 53
    • 0032985806 scopus 로고    scopus 로고
    • Chemotherapy for renal cell carcinoma
    • Hartmann JT, Bokemeyer C (1999) Chemotherapy for renal cell carcinoma. Anticancer Res 19:1541-1544
    • (1999) Anticancer Res , vol.19 , pp. 1541-1544
    • Hartmann, J.T.1    Bokemeyer, C.2
  • 55
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE (2002) Multidrug resistance in cancer: Role of ATP-dependent transporters. Nat Rev Cancer 2:48-58
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 60
    • 0022508342 scopus 로고
    • Differences in phosphate metabolite levels in drug-sensitive and -resistant human breast cancer cell lines determined by 31P magnetic resonance spectroscopy
    • Cohen JS, Lyon RC, Chen C, Faustino PJ, Batist G, Shoemaker M, Rubalcaba E, Cowan KH (1986) Differences in phosphate metabolite levels in drug-sensitive and -resistant human breast cancer cell lines determined by 31P magnetic resonance spectroscopy. Cancer Res 46:4087-4090
    • (1986) Cancer Res , vol.46 , pp. 4087-4090
    • Cohen, J.S.1    Lyon, R.C.2    Chen, C.3    Faustino, P.J.4    Batist, G.5    Shoemaker, M.6    Rubalcaba, E.7    Cowan, K.H.8
  • 61
    • 0033042826 scopus 로고    scopus 로고
    • Changes in membrane microdomains and caveolae constituents in multidrug-resistant cancer cells
    • Lavie Y, Fiucci G, Czarny M, Liscovitch M (1999) Changes in membrane microdomains and caveolae constituents in multidrug-resistant cancer cells. Lipids 34:S57-S63
    • (1999) Lipids , vol.34
    • Lavie, Y.1    Fiucci, G.2    Czarny, M.3    Liscovitch, M.4
  • 62
    • 0030869122 scopus 로고    scopus 로고
    • The P-glycoprotein multidrug transporter: Interactions with membrane lipids, and their modulation of activity
    • Sharom FJ (1997) The P-glycoprotein multidrug transporter: interactions with membrane lipids, and their modulation of activity. Biochem Soc Trans 25:1088-1096
    • (1997) Biochem Soc Trans , vol.25 , pp. 1088-1096
    • Sharom, F.J.1
  • 63
    • 0026922073 scopus 로고
    • Phospholipid metabolites as indicators of cancer cell function
    • Ruiz-Cabello J, Cohen JS (1992) Phospholipid metabolites as indicators of cancer cell function. NMR Biomed. 5:226-33
    • (1992) NMR Biomed. , vol.5 , pp. 226-233
    • Ruiz-Cabello, J.1    Cohen, J.S.2
  • 64
    • 0023238954 scopus 로고
    • Response-specific adriamycin sensitivity markers provided by in vivo 31P nuclear magnetic resonance spectroscopy in murine mammary adenocarcinomas
    • Evelhoch JL, Keller NA, Corbett TH (1987) Response-specific adriamycin sensitivity markers provided by in vivo 31P nuclear magnetic resonance spectroscopy in murine mammary adenocarcinomas. Cancer Res 47:3396-3401
    • (1987) Cancer Res , vol.47 , pp. 3396-3401
    • Evelhoch, J.L.1    Keller, N.A.2    Corbett, T.H.3
  • 65
    • 0025923462 scopus 로고
    • 31P nuclear magnetic resonance spectroscopy, histology and cytokinetics of a xenografted hypopharynx carcinoma following treatment with cisplatin: Comparison in three sublines with increasing resistance
    • Tausch-Treml R, Kopf-Maier P, Baumgart F, Gewiese B, Ziessow D, Scherer H, Wolf KJ (1991) 31P nuclear magnetic resonance spectroscopy, histology and cytokinetics of a xenografted hypopharynx carcinoma following treatment with cisplatin: Comparison in three sublines with increasing resistance. Br J Cancer 64:485-493
    • (1991) Br J Cancer , vol.64 , pp. 485-493
    • Tausch-Treml, R.1    Kopf-Maier, P.2    Baumgart, F.3    Gewiese, B.4    Ziessow, D.5    Scherer, H.6    Wolf, K.J.7
  • 67
    • 0034333414 scopus 로고    scopus 로고
    • Phospholipids as multidrug resistance modulators of the transport of epirubicin in human intestinal epithelial Caco-2 cell layers and everted gut sacs of rats
    • Lo Y-L (2000) Phospholipids as multidrug resistance modulators of the transport of epirubicin in human intestinal epithelial Caco-2 cell layers and everted gut sacs of rats. Biochem Pharmacol 60:1381-1390
    • (2000) Biochem Pharmacol , vol.60 , pp. 1381-1390
    • Lo, Y.-L.1
  • 68
    • 0035849506 scopus 로고    scopus 로고
    • Phospholipid flippase activity of the reconsituted P-glycoprotein multidrug transporter
    • Romsicki Y, Sharom FJ (2001) Phospholipid flippase activity of the reconsituted P-glycoprotein multidrug transporter. Biochemistry 40:6937-6947
    • (2001) Biochemistry , vol.40 , pp. 6937-6947
    • Romsicki, Y.1    Sharom, F.J.2
  • 69
    • 0035819885 scopus 로고    scopus 로고
    • Targeting ceramide metabolism - A strategy for overcoming drug resistance
    • Senchenkov A, Litvak DA, Cabot MC (2001) Targeting ceramide metabolism - a strategy for overcoming drug resistance. J Natl Cancer Inst 93:347-357
    • (2001) J Natl Cancer Inst , vol.93 , pp. 347-357
    • Senchenkov, A.1    Litvak, D.A.2    Cabot, M.C.3
  • 70
    • 0032731917 scopus 로고    scopus 로고
    • Domain exchangeability between the multidrug transporter (MDR1) and phosphatidylcholine flippase (MDR2)
    • Zhou Y, Gottesman M, Pastan I (1999) Domain exchangeability between the multidrug transporter (MDR1) and phosphatidylcholine flippase (MDR2). Mol Pharmacol 56:997-1004
    • (1999) Mol Pharmacol , vol.56 , pp. 997-1004
    • Zhou, Y.1    Gottesman, M.2    Pastan, I.3
  • 71
    • 0029828921 scopus 로고    scopus 로고
    • Modulation of mdr1 expression by cytokines in human colon carcinoma cells: An approach for reversal of multidrug resistance
    • Stein U, Walther W, Shoemaker RH (1996) Modulation of mdr1 expression by cytokines in human colon carcinoma cells: an approach for reversal of multidrug resistance. Br J Cancer 74:1384-1391
    • (1996) Br J Cancer , vol.74 , pp. 1384-1391
    • Stein, U.1    Walther, W.2    Shoemaker, R.H.3
  • 73
    • 0033018226 scopus 로고    scopus 로고
    • Adjuvant immunotherapy in renal cell carcinoma - Comparison of interferon alpha treatment with an untreated control
    • Basting R, Corvin S, Haendel D, Hinke A, Schmidt D (1999) Adjuvant immunotherapy in renal cell carcinoma - comparison of interferon alpha treatment with an untreated control. Anticancer Res 19:1545-1548
    • (1999) Anticancer Res , vol.19 , pp. 1545-1548
    • Basting, R.1    Corvin, S.2    Haendel, D.3    Hinke, A.4    Schmidt, D.5
  • 74
    • 0031565163 scopus 로고    scopus 로고
    • Results of ambulatory mono- and combined interferon therapy in advanced kidney tumors
    • Buzogany I, Czvalinga I, Gotz F (1997) Results of ambulatory mono- and combined interferon therapy in advanced kidney tumors. Orv Hetil 138:67-70
    • (1997) Orv Hetil , vol.138 , pp. 67-70
    • Buzogany, I.1    Czvalinga, I.2    Gotz, F.3
  • 75
    • 0035200452 scopus 로고    scopus 로고
    • Vinblastin-carboplatin for metastatic cutaneous melanoma as first-line chemotherapy and in dacarbazine failures
    • Jelic S, Babovic N, Stamatovic L, Kreacic M, Matkovic S, Popov I (2001) Vinblastin-carboplatin for metastatic cutaneous melanoma as first-line chemotherapy and in dacarbazine failures. Med Oncol 18:189-195
    • (2001) Med Oncol , vol.18 , pp. 189-195
    • Jelic, S.1    Babovic, N.2    Stamatovic, L.3    Kreacic, M.4    Matkovic, S.5    Popov, I.6
  • 76
    • 0030738677 scopus 로고    scopus 로고
    • Multidrug resistance: Molecular mechanisms and clinical relevance
    • Ling V (1997) Multidrug resistance: Molecular mechanisms and clinical relevance. Cancer Chemother Pharmacol 40:S3-S8
    • (1997) Cancer Chemother Pharmacol , vol.40
    • Ling, V.1
  • 78
    • 0022540085 scopus 로고
    • Hyponatremia and other toxic effects during a phase I trial of recombinant human gamma interferon and vinblastine
    • Bennett CL, Vogelzang NJ, Ratain MJ, Reich SD (1986) Hyponatremia and other toxic effects during a phase I trial of recombinant human gamma interferon and vinblastine. Cancer Treat Rep 70:1081-1084
    • (1986) Cancer Treat Rep , vol.70 , pp. 1081-1084
    • Bennett, C.L.1    Vogelzang, N.J.2    Ratain, M.J.3    Reich, S.D.4
  • 80
    • 0025360452 scopus 로고
    • Antiproliferative and antitumor effects of a-interferon in renal cell carcinomas: Correlation with the expression of a kidney-associated differentiation glycoprotein
    • Nanus DM, Pfeffer LM, Bander NH, Bahri S, Albino AP (1990) Antiproliferative and antitumor effects of a-interferon in renal cell carcinomas: Correlation with the expression of a kidney-associated differentiation glycoprotein. Cancer Res 50:4190-4194
    • (1990) Cancer Res , vol.50 , pp. 4190-4194
    • Nanus, D.M.1    Pfeffer, L.M.2    Bander, N.H.3    Bahri, S.4    Albino, A.P.5


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