Novel endomorphin-2 analogs with μ-opioid receptor antagonist activity

Journal of Peptide Research

Volumn 66, Issue 3, 2005, Pages 125-131

  Kruszynski, R ^a   Fichna, J ^b   Do Rego, J C ^c   Chung, N N ^d   Schiller, P W ^d   Kosson, P ^e   Costentin, J ^c   Janecka, A ^b  

^a LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

^b MEDICAL UNIVERSITY OF LODZ   (Poland)

^c UNIVERSITÉ DE ROUEN   (France)

^d CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^e MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Analgesia; Binding studies; Hot plate test; Peptide analogs

Indexed keywords

DEXTRO 1 3 (1 NAPHTHYL) ALANINE ENDOMORPHIN 2; DEXTRO 2 3 (2 NAPHTHYL) ALANINE ENDOMORPHIN 2; ENDOMORPHIN 2; MU OPIATE RECEPTOR ANTAGONIST; NALOXONE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GUINEA PIG; HOT PLATE TEST; IC 50; ILEUM; MALE; NONHUMAN; PRIORITY JOURNAL; VAS DEFERENS;

ALANINE; ANALGESICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDORPHINS; GUINEA PIGS; MALE; MICE; NAPHTHALENES; NARCOTIC ANTAGONISTS; OLIGOPEPTIDES; RATS; RATS, WISTAR; RECEPTORS, OPIOID, MU; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; CAVIA PORCELLUS;

EID: 23844476819     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.2005.00282.x     Document Type: Article

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