Mitogenic effects of the up-regulation of minichromosome maintenance proteins in anaplastic thyroid carcinoma

Journal of Clinical Endocrinology and Metabolism

Volumn 90, Issue 8, 2005, Pages 4703-4709

  Guida, Teresa ^a   Salvatore, Giuliana ^a   Faviana, Pinuccia ^b   Giannini, Riccardo ^b   Garcia Rostan, Ginesa ^c   Provitera, Livia ^a   Basolo, Fulvio ^b   Fusco, Alfredo ^a   Carlomagno, Francesca ^a   Santoro, Massimo ^a,d  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c UNIVERSITY OF PORTO   (Portugal)

^d UNIVERSITY OF CHIETI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MINICHROMOSOME MAINTENANCE PROTEIN; MINICHROMOSOME MAINTENANCE PROTEIN 2; RNA;

ANAPLASTIC CARCINOMA; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA REPLICATION; DNA SYNTHESIS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MINICHROMOSOME; MITOGENICITY; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REDUCTION; THYROID CARCINOMA; THYROID CELL; TRANSGENIC MOUSE; UPREGULATION; WILD TYPE;

ANIMALS; CARCINOMA, PAPILLARY; CELL CYCLE PROTEINS; CELL DIVISION; CELLS, CULTURED; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, TRANSGENIC; MITOGENS; NUCLEAR PROTEINS; RNA, MESSENGER; THYROID NEOPLASMS; UP-REGULATION;

EUKARYOTA; MUS MUSCULUS;

EID: 23844474029     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-2459     Document Type: Article

References (36)

1. Sherman SI 2003 Thyroid carcinoma. Lancet 361:501-511
2. McIver B, Hay ID, Giuffrida DF, Dvorak CE, Grant CS, Thompson GB, van Heerden JA, Goellner JR 2001 Anaplastic thyroid carcinoma: a 50-year experience at a single institution. Surgery 130:1028-1034
3. Ain KB 1999 Anaplastic thyroid carcinoma: a therapeutic challenge. Semin Surg Oncol 16:64-69
4. Ordonez N, Baloch Z, Matias-Guiu X, Evans H, Farid NR, Fagin JA, Kitamura Y, Tallini G, Eng C, Haigh PI, Faquin WC, Sugitani I, Giuffrida D, Boerner S 2004 Undifferentiated (anaplastic) carcinoma. In: DeLellis RA, Lloyd RV, Heitz PU, Eng C, eds. Pathology and genetics of tumours of endocrine organs (IARC/World Health Organization classification of tumors). Lyon: International Agency for Research on Cancer; 77-80
5. Garcia-Rostan G, Zhao H, Camp RL, Pollan M, Herrero A, Pardo J, Wu R, Carcangiu ML, Costa J, Tallini G 2003 ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer. J Clin Oncol 21:3226-3235
6. Nikiforova MN, Kimura ET, Gandhi M, Biddinger PW, Knauf JA, Basolo F, Zhu Z, Giannini R, Salvatore G, Fusco A, Santoro M, Fagin JA, Nikiforov YE 2003 BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas. J Clin Endocrinol Metab 88:5399-5404
7. Fagin JA, Matsuo K, Karmakar A, Chen DL, Tang SH, Koeffler HP 1993 High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest 91:179-184
8. Donghi R, Longoni A, Pilotti S, Michieli P, Della Porta G, Pierotti MA 1993 Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland. J Clin Invest 91:1753-1760
9. Garcia-Rostan G, Tallini G, Herrero A, D'Aquila TG, Carcangiu ML, Rimm DL 1999 Frequent mutation and nuclear localization of β-catenin in anaplastic thyroid carcinoma. Cancer Res 59:1811-1815
10. Wreesmann VB, Ghossein RA, Patel SG, Harris CP, Schnaser EA, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B 2002 Genome-wide appraisal of thyroid cancer progression. Am J Pathol 161:1549-1556
11. Kadota M, Tamaki Y, Sakita I, Komoike Y, Miyazaki M, Ooka M, Masuda N, Fujiwara Y, Ohnishi T, Tomita N, Sekimoto M, Ohue M, Ikeda T, Kobayashi T, Horii A, Monden M 2000 Identification of a 7-cM region of frequent allelic loss on chromosome band 16p13.3 that is specifically associated with anaplastic thyroid carcinoma. Oncol Rep 7:529-533
12. Bell SP, Dutta A 2002 DNA replication in eukaryotic cells. Annu Rev Biochem 71:333-374
13. Labib K, Tercero JA, Diffley JF 2000 Uninterrupted MCM2-7 function required for DNA replication fork progression. Science 288:1643-1647
14. Pacek M, Walter JC 2004 A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication. EMBO J 23:3667-3676
15. Stoeber K, Tlsty TD, Happerfield L, Thomas GA, Romanov S, Bobrow L, Williams ED, Williams GH 2001 DNA replication licensing and human cell proliferation. J Cell Sci 114:2027-2041
16. Williams GH, Romanowski P, Morris L, Madine M, Mills AD, Stoeber K, Marr J, Laskey RA, Coleman N 1998 Improved cervical smear assessment using antibodies against proteins that regulate DNA replication. Proc Natl Acad Sci USA 95:14932-14937
17. Freeman A, Morris LS, Mills AD, Stoeber K, Laskey RA, Williams GH, Coleman N 1999 Minichromosome maintenance proteins as biological markers of dysplasia and malignancy. Clin Cancer Res 5:2121-2132
18. Williams GH, Swinn R, Prevost AT, De Clive-Lowe P, Halsall I, Going JJ, Hales CN, Stoeber K, Middleton SJ 2004 Diagnosis of oesophageal cancer by detection of minichromosome maintenance 5 protein in gastric aspirates. Br J Cancer 91:714-719
19. Meng MV, Grossfeld GD, Williams GH, Dilworth S, Stoeber K, Mulley TW, Weinberg V, Carroll PR, Tlsty TD 2001 Minichromosome maintenance protein 2 expression in prostate: characterization and association with outcome after therapy for cancer. Clin Cancer Res 7:2712-2718
20. Stoeber K, Halsall I, Freeman A, Swinn R, Doble A, Morris L, Coleman N, Bullock N, Laskey RA, Hales CN, Williams GH 1999 Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine. Lancet 354:1524-1525
21. Davies RJ, Freeman A, Morris LS, Bingham S, Dilworth S, Scott I, Laskey RA, Miller R, Coleman N 2002 Analysis of minichromosome maintenance proteins as a novel method for detection of colorectal cancer in stool. Lancet 359:1917-1919
22. Hedinger C, Williams ED, Sobin LH 1989 The WHO histological classification of thyroid tumors: a commentary on the ed. 2. Cancer 63:908-911
23. Fujita M, Kiyono T, Hayashi Y, Ishibashi M 1997 In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP. J Biol Chem 272:10928-10935
24. Suzuki S, Adachi A, Hiraiwa A, Ohashi M, Ishibashi M, Kiyono T 1998 Cloning and characterization of human MCM7 promoter. Gene 216:85-91
25. Battista S, Martelli ML, Fedele M, Chiappetta G, Trapasso F, De Vita G, Battaglia C, Santoro M, Viglietto G, Fagin JA, Fusco A 1995 A mutated p53 gene alters thyroid cell differentiation. Oncogene 11:2029-2037
26. Hingorani SR, Jacobetz MA, Robertson GP, Herlyn M, Tuveson DA 2003 Suppression of BRAF(V599E) in human melanoma abrogates transformation. Cancer Res 63:5198-5202
27. Ledent C, Dumont J, Vassart G, Parmentier M 1991 Thyroid adenocarcinomas secondary to tissue-specific expression of simian virus-40 large T-antigen in transgenic mice. Endocrinology 129:1391-1401
28. Powell Jr DJ, Russell J, Nibu K, Li G, Rhee E, Liao M, Goldstein M, Keane WM, Santoro M, Fusco A, Rothstein JL 1998 The RET/PTC3 oncogene: metastatic solid-type papillary carcinomas in murine thyroids. Cancer Res 58: 5523-5528
29. Russell JP, Powell DJ, Cunnane M, Greco A, Portella G, Santoro M, Fusco A, Rothstein JL 2000 The TRK-T1 fusion protein induces neoplastic transformation of thyroid epithelium. Oncogene 19:5729-5735
30. Cromer A, Carles A, Millon R, Ganguli G, Chalmel F, Lemaire F, Young J, Dembele D, Thibault C, Muller D, Poch O, Abecassis J, Wasylyk B 2004 Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysis. Oncogene 23:2484-2498
31. Muller H, Bracken AP, Vernell R, Moroni MC, Christians F, Grassilli E, Prosperini E, Vigo E, Oliner JD, Helin K 2001 E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes Dev 15:267-285
32. Hickman ES, Moroni MC, Helin K 2002 The role of p53 and pRB in apoptosis and cancer. Curr Opin Genet Dev 12:60-66
33. Nguyen VQ, Co C, Li JJ 2001 Cyclin-dependent kinases prevent DNA rereplication through multiple mechanisms. Nature 411:1068-1073
34. Bruemmer D, Yin F, Liu J, Kiyono T, Fleck E, Van Herle AJ, Law RE 2003 Expression of minichromosome maintenance proteins in vascular smooth muscle cells is ERK/MAPK dependent. Exp Cell Res 290:28-37
35. Bruemmer D, Yin F, Liu J, Kiyono T, Fleck E, Van Herle AJ, Law RE 2003 Rapamycin inhibits E2F-dependent expression of minichromosome maintenance proteins in vascular smooth muscle cells. Biochem Biophys Res Commun 303:251-258
36. Vasko V, Saji M, Hardy E, Kruhlak M, Larin A, Savchenko V, Miyakawa M, Isozaki O, Murakami H, Tsushima T, Burman KD, De Micco C, Ringel MD 2004 Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer. J Med Genet 41:161-170