Key roles of hydrophobic rings of TM2 in gating of the α9α10 nicotinic cholinergic receptor

British Journal of Pharmacology

Volumn 145, Issue 7, 2005, Pages 963-974

  Plazas, Paola V ^a   De Rosa, María J ^b   Gomez Casati, María E ^a   Verbitsky, Miguel ^a,d   Weisstaub, Noelia ^a,e   Katz, Eleonora ^a,c   Bouzat, Cecilia ^b   Elgoyhen, Ana Belén ^a  

^a INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

^b UNIVERSIDAD NACIONAL DEL SUR   (Argentina)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^d Columbia University ^*  (United States)

^e Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Acetylcholine; Channel gating; Cys loop receptors; Ionotropic receptors; Nicotinic receptors

Indexed keywords

NICOTINIC RECEPTOR; PARTIAL AGONIST; TROPISETRON;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC ORGAN; EXTRACELLULAR CALCIUM; HYDROPHILICITY; HYDROPHOBICITY; ION TRANSPORT; MEMBRANE POTENTIAL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RING OPENING; XENOPUS LAEVIS;

ACETYLCHOLINE; ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CHOLINERGIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ION CHANNEL GATING; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PATCH-CLAMP TECHNIQUES; PHENOTYPE; PROTEIN SUBUNITS; RECEPTORS, NICOTINIC; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; TRANSFECTION; XENOPUS LAEVIS;

EID: 23744483520     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706224     Document Type: Article

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