Spatial and temporal profiles of flare and hyperalgesia after intradermal capsaicin

Pain

Volumn 105, Issue 1-2, 2003, Pages 285-291

  Sumikura, H ^a   Andersen, O K ^a   Drewes, A M ^a,b   Arendt Nielsen, L ^a  

^a AALBORG UNIVERSITY   (Denmark)

^b AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Capsaicin; Heat hyperalgesia; Intradermal injection; Laser Doppler flowmetry; Thermography; Visual flare

Indexed keywords

CAPSAICIN;

ARTICLE; BLOOD FLOW; CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; HUMAN EXPERIMENT; HYPERALGESIA; LASER DOPPLER FLOWMETRY; MEDICAL ASSESSMENT; NEUROGENIC INFLAMMATION; NORMAL HUMAN; PRIORITY JOURNAL; SPATIAL MEMORY; STIMULUS RESPONSE; TEMPERATURE DEPENDENCE; TEMPORAL LOBE; THERMOGRAPHY;

EID: 0141850315     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(03)00243-4     Document Type: Article

References (34)

1. Ali Z., Meyer R.A., Campbell J.N. Secondary hyperalgesia to mechanical but not heat stimuli following a capsaicin injection in hairy skin. Pain. 68:1996;401-411.
2. Andrew D., Greenspan J.D. Mechanical and heat sensitization of cutaneous nociceptors after peripheral inflammation in the rat. J Neurophysiol. 82:1999;2649-2656.
3. 2 and argon laser stimulation. Eur J Appl Physiol. 58:1988;266-273.
4. Arendt-Nielsen L., Andersen O.K., Jensen T.S. Brief, prolonged, and repeated stimuli applied to hyperalgesic skin areas: a psychophysical study. Brain Res. 712:1996;165-167.
5. Benrath J., Gillardon F., Zimmermann M. Differential time courses of skin blood flow and hyperalgesia in the human sunburn reaction following ultraviolet irradiation of the skin. Eur J Pain. 5:2001;155-167.
6. Bromm B., Jahnke M.T., Treede R.D. Responses of human cutaneous afferents to CO2 laser stimuli causing pain. Exp Brain Res. 55:1984;158-166.
7. Cervero F., Meyer R.A., Campbell J.N. A psychophysical study of secondary hyperalgesia: evidence for increased pain to input from nociceptors. Pain. 58:1994;21-28.
8. Dahl J.B., Brennum J., Arendt-Nielsen L., Jensen T.S., Kehlet H. The effect of pre- versus postinjury infiltration with lidocaine on thermal and mechanical hyperalgesia after heat injury to the skin. Pain. 53:1993;43-51.
9. Francis J.E., Roggli R., Love T.J., Robinson C.P. Thermography as a means of blood perfusion measurement. J Biomech Eng. 101:1979;246-249.
10. Forster C., Greiner T., Nischik M., Schmelz M., Handwerker H.O. Neurogenic flare responses are heterogeneous in superficial and deep layers of human skin. Neurosci Lett. 185:1995;33-36.
11. Fuchs P.N., Campbell J.N., Meyer R.A. Secondary hyperalgesia persists in capsaicin desensitized skin. Pain. 84:2000;141-149.
12. Haudas Y., Ring E.F.J. Human body temperature, its measurement and regulation. 1982;Plenum, New York.
13. Huang J.H., Ali Z., Travison T.G., Campbell J.N., Meyer R.A. Spatial mapping of the zone of secondary hyperalgesia reveals a gradual decline of pain with distance but sharp borders. Pain. 86:2000;33-42.
14. Kidd B.L., Urban L.A. Mechanisms of inflammatory pain. Br J Anaesth. 87:2001;3-11.
15. Koda H., Mizumura K. Sensitization to mechanical stimulation by inflammatory mediators and by mild burn in canine visceral nociceptors in vitro. J Neurophysiol. 87:2002;2043-2051.
16. Koppert W., Ostermeier N., Sittl R., Weidner C., Schmelz M. Low-dose lidocaine reduces secondary hyperalgesia by a central mode of action. Pain. 85:2000;217-224.
17. LaMotte R.H., Shain C.N., Simone D.A., Tsai E.F.P. Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms. J Neurophysiol. 66:1991;190-211.
18. Levine J.D., Reichling D.B. Peripheral mechanism of inflammatory pain. Wall P.D., Melzack R. Textbook of pain. 4th ed:1999;59-84 Churchill Livingstone, London.
19. Lewis T. The blood vessels of the human skin and their response. 1927;Shaw, London.
20. Lin Q., Wu J., Willis W.D. Dorsal root reflexes and cutaneous neurogenic inflammation after intradermal injection of capsaicin in rats. J Neurophysiol. 82:1999;2602-2611.
21. Pappagallo M., Oaklander A.L., Quatrano-Piacentini A.L., Clark M.R., Raja S.N. Heterogeneous patterns of sensory dysfunction in postherpetic neuralgia suggest multiple pathophysiologic mechanisms. Anesthesiology. 92:2000;691-698.
22. Quinn A.G., McLelland J., Essex T., Farr P.M. Measurement of cutaneous inflammatory reactions using a scanning laser-Doppler velocimeter. Br J Dermatol. 125:1991;30-37.
23. Raja S.N., Campbell J.N., Meyer R.A. Evidence for different mechanisms of primary and secondary hyperalgesia following heat injury to the glabrous skin. Brain. 107:1984;1179-1188.
24. Raja S.N., Meyer R.A., Ringkamp M., Campbell J. Peripheral neural mechanism of nociception. Wall P.D., Melzack R. Textbook of pain. 4th ed:1999;11-58 Churchill Livingstone, London.
25. Serra J., Campero M., Ochoa J. Flare and hyperalgesia after intradermal capsaicin injection in human skin. J Neurophysiol. 80:1998;2801-2810.
26. Serra J., Campero M., Bostock H., Ochoa J. Responses of afferent C units in human skin to remote intradermal capsaicin injection. 10th World Congress on Pain abstract book. 2002.
27. Taylor G.I., Palmer J.H. The vascular territories (angiosomes) of the body: experimental study and clinical applications. Br J Plast Surg. 40:1987;113-141.
28. Torebjork H.E., Lundberg L.E., LaMotte R.H. Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans. J Physiol. 448:1992;765-780.
29. Treede R.D., Meyer R.A., Raja S.N., Campbell J.N. Peripheral and central mechanisms of cutaneous hyperalgesia. Prog Neurobiol. 38:1992;397-421.
30. Wallace M.S., Laitin S., Licht D., Yaksh T.L. Concentration-effect relations for intravenous lidocaine infusions in human volunteers: effects on acute sensory thresholds and capsaicin-evoked hyperpathia. Anesthesiology. 86:1997;1262-1272.
31. Wu G., Campbell J.N., Meyer R.A. Effects of baseline skin temperature on pain ratings to suprathreshold temperature-controlled stimuli. Pain. 90:2001;151-156.
32. Yeomans D.C., Pirec V., Proudfit H.K. Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: behavioral evidence. Pain. 68:1996;133-140.
33. Yucel A., Andersen O.K., Nielsen J., Arendt-Nielsen L. Heat hyperalgesia in humans: assessed by different stimulus temperature profiles. Eur J Pain. 6:2002;357-364.
34. Ziegler E.A., Magerl W., Meyer R.A., Treede R.D. Secondary hyperalgesia to punctate mechanical stimuli. Central sensitization to A-fibre nociceptor input. Brain. 122:1999;2245-2257.