Motilin and erythromycin-A share a common binding site in the third transmembrane segment of the motilin receptor

Biochemical Pharmacology

Volumn 70, Issue 6, 2005, Pages 879-887

  Xu, Luo ^a   Depoortere, Inge ^a   Vertongen, Pascale ^b   Waelbroeck, Magali ^b   Robberecht, Patrick ^b   Peeters, Theo L ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Ca2+ luminescence; Erythromycin A; Motilin fragments; Motilin receptor; Mutagenesis

Indexed keywords

AEQUORIN; CALCIUM; ERYTHROMYCIN; MOTILIN; SUGAR;

ACETYLATION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CHEMOLUMINESCENCE; CHO CELL; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG POTENCY; GENETIC TRANSFECTION; MEMBRANE REACTOR; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RECEPTOR BINDING;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BLOTTING, WESTERN; CHO CELLS; CRICETINAE; ERYTHROMYCIN; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; MOTILIN; RECEPTORS, GASTROINTESTINAL HORMONE; RECEPTORS, NEUROPEPTIDE; SWINE;

EID: 23744448032     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.06.022     Document Type: Article

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