Efficacy of an adenosine A1 receptor agonist compared with atropine and pralidoxime in a rat model of organophosphate poisoning

Human and Experimental Toxicology

Volumn 24, Issue 7, 2005, Pages 369-375

  Kalkan, S ^a   Ergur, B U ^a   Akgun, A ^a   Kaplan, Y C ^a   Kinay, A O ^a   Tuncok, Yesim ^a  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

Atropine; Organophosphate, PAM; Phenylisopropyl adenosine (PIA)

Indexed keywords

ACETYLCHOLINESTERASE; ADENOSINE A1 RECEPTOR AGONIST; ATROPINE; METHAMIDOPHOS; ORGANOPHOSPHATE; PHENYLISOPROPYLADENOSINE; PRALIDOXIME; PRALIDOXIME MESILATE; SODIUM CHLORIDE; ADENOSINE A1 RECEPTOR; ANTIDOTE; CHOLINESTERASE; CHOLINESTERASE REACTIVATOR; INSECTICIDE; MUSCARINIC RECEPTOR BLOCKING AGENT; PHOSPHOROTHIOIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CONVULSION; DIAPHRAGM MUSCLE; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; HISTOPATHOLOGY; INTOXICATION; MORTALITY; MUSCLE NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY DISTRESS; SALIVATION; SURVIVAL; SYMPTOM; ANIMAL; BLOOD; BREATHING; COMPARATIVE STUDY; DIAPHRAGM; DRUG INTERACTION; DRUG POTENTIATION; MALE; METABOLISM; PATHOLOGY; SURVIVAL RATE; TIME; WISTAR RAT;

ANIMALIA;

ANIMALS; ANTIDOTES; ATROPINE; CHOLINESTERASE REACTIVATORS; CHOLINESTERASES; DIAPHRAGM; DRUG INTERACTIONS; INSECTICIDES; MALE; MODELS, ANIMAL; MUSCARINIC ANTAGONISTS; ORGANOTHIOPHOSPHORUS COMPOUNDS; PHENYLISOPROPYLADENOSINE; POISONING; PRALIDOXIME COMPOUNDS; RATS; RATS, WISTAR; RECEPTOR, ADENOSINE A1; RESPIRATION; SALIVATION; SURVIVAL RATE; TIME FACTORS;

EID: 23744432551     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/0960327105ht540oa     Document Type: Article

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