Regulation of p70S6k, GSK-3β, and calcineurin in rat striated muscle during aging

Biogerontology

Volumn 6, Issue 3, 2005, Pages 173-184

  Kinnard, R S ^a   Mylabathula, D B ^a   Uddemarri, S ^a   Rice, K M ^a   Wright, G L ^b   Blough, E R ^a,b  

^a MARSHALL UNIVERSITY   (United States)

^b MARSHALL UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Bax; Bcl 2; Calcineurin; EDL; GSK 3 ; p70S6k; Soleus

Indexed keywords

CALCINEURIN; CONTRACTILE PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN P70; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; PROTEIN SERINE THREONINE KINASE; S6 KINASE;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DIAPHRAGM MUSCLE; ENZYME ACTIVITY; EXTENSOR DIGITORUM LONGUS MUSCLE; HEART MUSCLE; IMMUNODETECTION; MUSCLE HYPERTROPHY; MUSCLE MASS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; RAT STRAIN; SKELETAL MUSCLE; SOLEUS MUSCLE; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BODY WEIGHT; COMPARATIVE STUDY; DIAPHRAGM; FISCHER 344 RAT; HEART; HISTOLOGY; MALE; METABOLISM; ORGAN SIZE;

AGING; ANIMALS; BODY WEIGHT; CALCINEURIN; DIAPHRAGM; GLYCOGEN SYNTHASE KINASE 3; HEART; MALE; MUSCLE, SKELETAL; MYOCARDIUM; ORGAN SIZE; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, INBRED F344; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA;

EID: 23644459978     PISSN: 13895729     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10522-005-7953-6     Document Type: Article

References (34)

1. CL Antos TA McKinsey N Frey W Kutschke J McAnally JM Shelton JA Richardson JA Hill and EN Olson 2002 Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo Proc Natl Acad Sci USA 99 907-912 10.1073/pnas.231619298 11782539
2. K Baar and K Esser 1999 Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exercise Am J Physiol 276 C120-127 9886927
3. RN Baumgartner KM Koehler D Gallagher L Romero SB Heymsfield RR Ross PJ Garry and RD Lindeman 1998 Epidemiology of sarcopenia among the elderly in New Mexico Am J Epidemiol 147 755-763 9554417
4. X Bigard H Sanchez J Zoll P Mateo V Rousseau V Veksler and R Ventura-Clapier 2000 Calcineurin Co-regulates contractile and metabolic components of slow muscle phenotype J Biol Chem 275 19653-19660 10.1074/ jbc.M000430200 10777482
5. ER Blough and JK Linderman 2000 Lack of skeletal muscle hypertrophy in very aged male Fischer 344 x Brown Norway rats J Appl Physiol 88 1265-1270 10749817
6. SC Bodine TN Stitt M Gonzalez WO Kline GL Stover R Bauerlein E Zlotchenko A Scrimgeour JC Lawrence DJ Glass and GD Yancopoulos 2001 Akt/ mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo Nat Cell Biol 3 1014-1019 10.1038/ ncb1101-1014 11715023
7. MM Chou and J Blenis 1995 The 70 kDa S6 kinase: Regulation of a kinase with multiple roles in mitogenic signalling Curr Opin Cell Biol 7 806-814 10.1016/0955-0674(95)80064-6 8608011
8. H Degens and SE Alway 2003 Skeletal muscle function and hypertrophy are diminished in old age Muscle Nerve 27 339-347 10.1002/mus.10314 12635121
9. GW Dorn II and T Force 2005 Protein kinase cascades in the regulation of cardiac hypertrophy J Clin Invest 115 527-537 10.1172/JCI200524178 15765134
10. A. Dufner and G Thomas 1999 Ribosomal S6 kinase signaling and the control of translation Exp Cell Res 253 100-109 10.1006/excr.1999.4683 10579915
11. SE Dunn ER Chin and RN Michel 2000 Matching of calcineurin activity to upstream effectors is critical for skeletal muscle fiber growth J Cell Biol 151 663-672 10.1083/jcb.151.3.663 11062266
12. LP Fried 2000 Epidemiology of aging Epidemiol Rev 22 95-106 10939013
13. TC Grammer L Cheatham MM Chou and J Blenis 1996 The p70 S6K signalling pathway: A novel signalling system involved in growth regulation Cancer Surv 27 271-292 8909805
14. CA Grimes and RS Jope 2001 The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling Prog Neurobiol 65 391-426 10.1016/ S0301-0082(01)00011-9 11527574
15. S Haq G Choukroun ZB Kang H Ranu T Matsui A Rosenzweig JD Molkentin A Alessandrini J Woodgett and R Hajjar 2000 Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy J Cell Biol 151 117-130 10.1083/jcb.151.1.117 11018058
16. SE Hardt H Tomita HA Katus and J Sadoshima 2004 Phosphorylation of eukaryotic translation initiation factor 2Bepsilon by glycogen synthase kinase-3beta regulates beta-adrenergic cardiac myocyte hypertrophy Circ Res 94 926-935 10.1161/01.RES.0000124977.59827.80 15001529
17. V Horsley and GK Pavlath 2002 NFAT: Ubiquitous regulator of cell differentiation and adaptation J Cell Biol 156 771-774 10.1083/ jcb.200111073 11877454
18. K Hughes E Nikolakaki SE Plyte NF Totty and JR Woodgett 1993 Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation Embo J 12 803-808 8382613
19. s6k Embo J 16 3693-3704 10.1093/emboj/16.12.3693 9218810
20. WJ Lee J McClung GA Hand and JA Carson 2003 Overload-induced androgen receptor expression in the aged rat hindlimb receiving nandrolone decanoate J Appl Physiol 94 1153-1161 12571141
21. KJ McCullagh E Calabria G Pallafacchina S Ciciliot AL Serrano C Argentini JM Kalhovde T Lomo and S Schiaffino 2004 NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching Proc Natl Acad Sci USA 101 10590-10595 10.1073/ pnas.0308035101 15247427
22. PO Mitchell ST Mills and GK Pavlath 2002 Calcineurin differentially regulates maintenance and growth of phenotypically distinct muscles Am J Physiol Cell Physiol 282 C984-992 11940513
23. Mitchell PO and Pavlath GK (2002) Multiple roles of calcineurin in skeletal muscle growth. Clin Orthop S197-202
24. M Pap and GM Cooper 2002 Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/ glycogen synthase kinase 3beta signaling pathway Mol Cell Biol 22 578-586 10.1128/MCB.22.2.578-586.2002 11756553
25. A Rao C Luo and PG Hogan 1997 Transcription factors of the NFAT family: regulation and function Annu Rev Immunol 15 707-747 10.1146/ annurev.immunol.15.1.707 9143705
26. C Rommel SC Bodine BA Clarke R Rossman L Nunez TN Stitt GD Yancopoulos and DJ Glass 2001 Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways Nat Cell Biol 3 1009-1013 10.1038/ncb1101-1009 11715022
27. R Roubenoff 2001 Origins and clinical relevance of sarcopenia Can J Appl Physiol 26 78-89 11291626
28. AG Ryazanov and BS Nefsky 2002 Protein turnover plays a key role in aging Mech Ageing Dev 123 207-213 10.1016/S0047-6374(01)00337-2 11718813
29. AL Serrano M Murgia G Pallafacchina E Calabria P Coniglio T Lomo and S Schiaffino 2001 Calcineurin controls nerve activity-dependent specification of slow skeletal muscle fibers but not muscle growth Proc Natl Acad Sci USA 98 13108-13113 10.1073/pnas.231148598 11606756
30. T Sugiura H Matoba H Miyata Y Kawai and N Murakami 1992 Myosin heavy chain isoform transition in ageing fast and slow muscles of the rat Acta Physiol Scand 144 419-423 1605043
31. H Towbin T Staehelin and J Gordon 1979 Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications Proc Natl Acad Sci USA 76 4350-4354 388439
32. L Tsao C Neville A Musaro KJ McCullagh and N Rosenthal 2000 Revisiting calcineurin and human heart failure Nat Med 6 2-3 10.1038/71478 10613792
33. DR Vyas EE Spangenburg TW Abraha TE Childs and FW Booth 2002 GSK-3beta negatively regulates skeletal myotube hypertrophy Am J Physiol Cell Physiol 283 C545-551 12107064
34. WF Ward 2000 The relentless effects of the aging process on protein turnover Biogerontology 1 195-199 10.1023/A:1010076818119 11707896