Enantioselective analysis of metoprolol in plasma using high-performance liquid chromatographic direct and indirect separations: Applications in pharmacokinetics

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 738, Issue 1, 2000, Pages 27-37

  Lanchote, Vera Lucia ^a   Bonato, Pierina Sueli ^a   Cerqueira, Paula Macedo ^a   Pereira, Valéria Adriana ^a   Cesarino, Evandro José ^b  

^a Faculdade Cie Farmaceuticas R   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Enantiomer separation; Metoprolol

Indexed keywords

HEPARIN; METOPROLOL; METOPROLOL TARTRATE;

ACCURACY; ADULT; ARTICLE; CONTROLLED STUDY; DERIVATIZATION; DRUG BLOOD LEVEL; DRUG DETERMINATION; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; INTERMETHOD COMPARISON; LIVER MICROSOME; MALE; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; TECHNIQUE;

ADRENERGIC BETA-ANTAGONISTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; KINETICS; METOPROLOL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM;

EID: 0033955206     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(99)00476-4     Document Type: Article

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