Enantioselective determination of metoprolol acidic metabolite in plasma and urine using liquid chromatography chiral columns: Applications to pharmacokinetics

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 783, Issue 2, 2003, Pages 433-441

  Cerqueira, Paula Macedo ^a   Boralli, Vanessa Bergamin ^a   Coelho, Eduardo Barbosa ^a   Lopes, Norberto Peporine ^a   Lopes Guimarães, Luis Fernando ^a   Bonato, Pierina Sueli ^a   Lanchote, Vera Lucia ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Circular dichroism; Enantiomer separation; Metoprolol

Indexed keywords

METABOLITES; PLASMAS;

ENANTIOSELECTIVE SEPARATIONS;

LIQUID CHROMATOGRAPHY;

DEBRISOQUINE; METOPROLOL;

ACIDITY; ARTICLE; CHIRALITY; CORRELATION COEFFICIENT; DEVICE; DRUG DETERMINATION; ENANTIOMER; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLITE; PHENOTYPE; PRIORITY JOURNAL; URINALYSIS;

ADRENERGIC BETA-ANTAGONISTS; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; METOPROLOL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, FLUORESCENCE; STEREOISOMERISM;

EID: 0037437645     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-0232(02)00705-5     Document Type: Article

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