Evaluation of experimental models of idiopathic pulmonary fibrosis

Drug Discovery Today: Disease Models

Volumn 1, Issue 3, 2004, Pages 329-336

  Mutsaers, Steven E ^a   McAnulty, Robin J ^b   Laurent, Geoffrey J ^b   Knight, Darryl A ^a,c  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c ST PAUL S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ASBESTOS; BLEOMYCIN; FLUORESCEIN ISOTHIOCYANATE; HAPTEN; MONOCROTALINE; NITROGEN DIOXIDE; OXIDIZING AGENT; OZONE; PHORBOL 13 ACETATE 12 MYRISTATE; SCLEROPROTEIN; SILICON DIOXIDE;

ASBESTOSIS; BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA; EXPERIMENTAL MODEL; EXTRACELLULAR MATRIX; GAS DIFFUSION; HUMAN; IDIOPATHIC DISEASE; IN VITRO STUDY; IN VIVO STUDY; IRRADIATION; LUNG FIBROSIS; LUNG FUNCTION; NONHUMAN; PATHOGENESIS; PNEUMOCONIOSIS; PNEUMONIA; REOVIRUS; REVIEW; SILICOSIS; WELDING FUME;

EID: 23644438201     PISSN: 17406757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmod.2004.11.007     Document Type: Review

References (45)

1. Mutsaers, S.E. et al. (1997) Mechanisms of tissue repair: from wound healing to fibrosis. Int. J. Biochem. Cell Biol. 29, 5-17
2. Marshall, R.P. et al. (1997) The pathogenesis of pulmonary fibrosis: is there a fibrosis gene? Int. J. Biochem. Cell Biol. 29, 107-120
3. Moodley, Y.P. et al. (2003) Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation. Am. J. Pathol. 163, 345-354
4. Scaffidi, A.K. et al. (2002) Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts. Br. J. Pharmacol. 136, 793-801
5. McAnulty, R.J. et al. (1997) Indomethacin suppresses the anti-proliferative effects of transforming growth factor-beta isoforms on fibroblast cell cultures. Biochem. J. 321, 639-643
6. Hashimoto, N. et al. (2004) Bone marrow-derived progenitor cells in pulmonary fibrosis. J. Clin. Invest. 113, 243-252
7. Liu, T. et al. (2004) FIZZ1 stimulation of myofibroblast differentiation. Am. J. Pathol. 164, 1315-1326
8. Moodley, Y.P. et al. (2003) Inverse effects of interleukin-6 on apoptosis of fibroblasts from pulmonary fibrosis and normal lungs. Am. J. Respir. Cell. Mol. Biol. 29, 490-498
9. Katzenstein, A.L. and Myers, J.L. (1998) Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification. Am. J. Respir. Crit. Care Med. 157 (4 Pt. 1), 1301-1315
10. American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias (2002) This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001. Am. J. Respir. Crit. Care Med, 165, 277-304
11. Hay, J. et al. (1991) Mechanisms of bleomycin-induced lung damage. Arch. Toxicol. 65, 81-94
12. Kolb, M. et al. (2002) Differences in the fibrogenic response after transfer of active transforming growth factor-beta 1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains. Am. J. Respir. Cell. Mol. Biol. 27, 141-150
13. Warshamana, G.S. et al. (2002) Susceptibility to asbestos-induced and transforming growth factor-beta 1-induced fibroproliferative lung disease in two strains of mice. Am. J. Respir. Cell. Mol. Biol. 27, 705-713
14. Chung, M.P. et al. (2003) Role of repeated lung injury and genetic background in bleomycin-induced fibrosis. Am. J. Respir. Cell. Mol. Biol. 29 (3 Pt. 1), 375-380
15. Wynn, TA. (2004) Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat. Rev. Immunol. 4, 583-594
16. Mutsaers, S.E. et al. (1998) Increased endothelin-1 and its localization during the development of bleomycin-induced pulmonary fibrosis in rats. Am. J. Respir. Cell. Mol. Biol. 18, 611-619
17. Borzone, G. et al. (2001) Bleomycin-induced chronic lung damage does not resemble human idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 163, 1648-1653
18. Harrison, J.H. Jr and Lazo, J.S. (1987) High dose continuous infusion of bleomycin in mice: a new model for drug-induced pulmonary fibrosis. J. Pharmacol. Exp. Ther. 243, 1185-1194
19. Yara, S. et al. (2001) FTS reduces bleomycin-induced cytokine and chemokine production and inhibits pulmonary fibrosis in mice. Clin. Exp. Immunol. 124, 77-85
20. Gabazza, E.C. et al. (2002) Bleomycin-induced lung fibrosis: the authors should have used another method to induce pulmonary lesions resembling human idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 165, 845-846 (author reply 846)
21. Baybutt, R.C. and Molteni, A. (1999) Dietary beta-carotene protects lung and liver parenchyma of rats treated with monocrotaline. Toxicology 137, 69-80
22. Czer, G.T. et al. (1986) Low-dose PGI2 prevents monocrotaline-induced thromboxane production and lung injury. J. Appl. Physiol. 60, 464-471
23. Baybutt, R.C. et al. (2002) Dietary fish oil protects against lung and liver inflammation and fibrosis in monocrotaline treated rats. Toxicology 175, 1-13
24. Hayashi, S. et al. (1995) Establishment of an animal model for pulmonary fibrosis in mice using monocrotaline. Toxicol. Pathol. 23, 63-71
25. Sikic, B.I. et al. (1978) Quantification of bleomycin pulmonary toxicity in mice by changes in lung hydroxyproline content and morphometric histopathology. Cancer Res. 38, 787-792
26. Roberts, S.N. et al. (1995) A novel model for human interstitial lung disease: hapten-driven lung fibrosis in rodents. J. Pathol. 176, 309-318
27. Christensen, P.J. et al. (1999) Induction of lung fibrosis in the mouse by intratracheal instillation of fluorescein isothiocyanate is not T-cell-dependent. Am. J. Pathol. 155, 1773-1779
28. Helene, M. et al. (1999) T cell independence of bleomycin-induced pulmonary fibrosis. J. Leukoc. Biol. 65, 187-195
29. Chitano, P. et al. (1995) Effect of oxidant air pollutants on the respiratory system: insights from experimental animal research. Eur. Respir. J. 8, 1357-1371
30. Last, J.A. et al. (1993) A new model of progressive pulmonary fibrosis in rats. Am. Rev. Respir. Dis. 148, 487-494
31. Farman, C.A. et al. (1999) Centriacinar remodeling and sustained pro-collagen gene expression after exposure to ozone and nitrogen dioxide. Am. J. Respir. Cell. Mol. Biol. 20, 303-311
32. Hirano, Y. et al. (2000) Early molecular and cellular events of oxidant-induced pulmonary fibrosis in rats. Toxicol. Appl. Pharmacol. 167, 173-181
33. Taylor, R.G. et al. (1985) Histopathologic features of phorbol myristate acetate-induced lung injury. Lab. Invest. 52, 61-70
34. Zuo, F. et al. (2002) Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc. Natl. Acad. Sci. USA 99, 6292-6297
35. Gado, K. et al. (2001) Mouse plasmacytoma: an experimental model of human multiple myeloma. Haematologica 86, 227-236
36. American Thoracic Society (2000) Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am. J. Respir. Crit. Care Med. 161(2 Pt. 1), 646-664
37. Williams, K. et al. (2004) Identification of spontaneous feline idiopathic pulmonary fibrosis: morphology and ultrastructural evidence for a type II pneumocyte defect. Chest 125, 2278-2288
38. Coin, P.G. et al. (1996) Pulmonary fibrogenesis after three consecutive inhalation exposures to chrysotile asbestos. Am. J. Respir. Crit. Care Med. 154, 1511-1519
39. Cummins, A.B. et al. (2003) Persistent localization of activated extracellular signal-regulated kinases (ERK 1/2) is epithelial cell-specific in an inhalation model of asbestosis. Am. J. Pathol. 162, 713-720
40. Zhang-Hoover, J. et al. (2001) CD40/CD40 ligand interactions are critical for elicitation of autoimmune-mediated fibrosis in the lung. J. Immunol. 166, 3556-3563
41. Pauluhn, J. et al. (2001) Rat model of lung fibrosis: comparison of functional, biochemical, and histopathological changes 4 months after single irradiation of the right hemithorax. Toxicology 161, 153-163
42. Majeski, E.I. et al. (2003) Respiratory reovirus 1/L induction of intraluminal fibrosis, a model of bronchiolitis obliterans organizing pneumonia, is dependent on T lymphocytes. Am. J. Pathol. 163, 1467-1479
43. Porter, D.W. et al. (2004) Progression of lung inflammation and damage in rats after cessation of silica inhalation. Toxicol. Sci. 79, 370-380
44. Yu, I.J. et al. (2001) Lung fibrosis in Sprague-Dawley rats, induced by exposure to manual metal arc-stainless steel welding fumes. Toxicol. Sci. 63, 99-106
45. Bonniaud, P. et al. (2004) Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis. J. Immunol. 173, 2099-2108