Identification, functional analysis and expression in a heterotopic heart transplant model of CXCL9 in the rat

Immunology

Volumn 112, Issue 1, 2004, Pages 87-93

  Mitsuhashi, Noboru ^a   Kearns Jonker, Mary ^a   Wu, Gordon D ^a   Bowdish, Michael E ^a   Jin, Yang Sun ^a   Mencel, Robert ^a   Zahorsky Reeves, Joanne ^a   Fischer Lougheed, Jacqueline ^a   Weinberg, Kenneth I ^a   Starnes, Vaughn A ^a   Cramer, Donald V ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Chemokines: monokines; Chemotaxis; Transplantation

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR3; CXCL9 CHEMOKINE; UNCLASSIFIED DRUG;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL INFILTRATION; CELL MIGRATION; CELL STRAIN COS1; CHEMOTAXIS; COMPARATIVE ANATOMY; DNA ISOLATION; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ANALYSIS; HEART GRAFT; HETEROTOPIC TRANSPLANTATION; INTERNALIZATION; ISOGRAFT; LYMPH NODE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SPLEEN; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFLAMMATORY AGENTS; CHEMOKINES, CXC; COS CELLS; DEXAMETHASONE; DNA, COMPLEMENTARY; GENE EXPRESSION; GLUCOCORTICOIDS; GRAFT SURVIVAL; HEART TRANSPLANTATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERFERON-GAMMA, RECOMBINANT; LYMPH NODES; MALE; MOLECULAR SEQUENCE DATA; RATS; RATS, INBRED ACI; RNA, MESSENGER; SPLEEN; TISSUE DISTRIBUTION;

EID: 2342662693     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2004.01855.x     Document Type: Article

References (31)

1. Rossi D, Zlotnik A. The biology of chemokines and their receptors. Annu Rev Immunol 2000; 18:217-42.
2. Mellado M, Rodriguez-Frade JM, Manes S, Martinez AC. Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation. Annu Rev Immunol 2001; 19:397-421.
3. Proudfoot AE. Chemokine receptors: multifaceted therapeutic targets. Nat Rev Immunol 2002; 2:106-15.
4. Sallusto F, Mackay CR, Lanzavecchia A. The role of chemokine receptors in primary, effector, and memory immune responses. Annu Rev Immunol 2000; 18:593-620.
5. Duquesnoy RJ, Demetris AJ. Immunopathology of cardiac transplant rejection. Curr Opin Cardiol 1995; 10:193-206.
6. Nelson PJ, Krensky AM. Chemokines, chemokine receptors, and allograft rejection. Immunity 2001; 14:377-86.
7. Gao W, Faia KL, Csizmadia V, Smiley ST, Soler D, King JA, Danoff TM, Hancock WW. Beneficial effects of targeting CCR5 in allograft recipients. Transplantation 2001; 72:1199-205.
8. Sallusto F, Kremmer E, Palermo B et al. Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells. Eur J Immunol 1999; 29:2037-45.
9. Bonecchi R, Bianchi G, Bordignon PP et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T cells (Th1s) and Th2s. J Exp Med 1998; 187:129-34.
10. + T cells. Transplantation 2000; 69:1147-55.
11. Hancock WW, Lu B, Gao W et al. Requirement of the chemokine receptor CXCR3 for acute allograft rejection. J Exp Med 2000; 192:1515-20.
12. Fahmy NM, Yamani MH, Starling RC et al. Chemokine and chemokine receptor gene expression indicates acute rejection of human cardiac transplants. Transplantation 2003; 75:72-8.
13. Jiankuo M, Xingbing W, Baojun H et al. Peptide nucleic acid antisense prolongs skin allograft survival by means of blockade of CXCR3 expression directing T cells into graft. J Immunol 2003; 170:1556-65.
14. Cramer DV, Chapman FA, Jaffee B, Jones EA, Makowka L. Inhibition of the pyrimidine biosynthetic pathway with S-8660, an analogue of brequinar sodium, prolongs cardiac allograft survival in rats. J Heart Lung Transplant 1993; 12:140-6.
15. Cramer DV, Chapman FA, Jaffee BD, Jones EA, Knoop M, Hreha-Eiras G, Makowka L. The effect of a new immunosuppressive drug, brequinar sodium, on heart, liver, and kidney allograft rejection in the rat. Transplantation 1992; 53:303-8.
16. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72:248-54.
17. Breathnach R, Chambon P. Organization and expression of eucaryotic split genes coding for proteins. Annu Rev Biochem 1981; 50:349-83.
18. Farber JM. A macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokines. Proc Natl Acad Sci USA 1990; 87: 5238-42.
19. Farber JM. HuMig; a new human member of the chemokine family of cytokines. Biochem Biophys Res Commun 1993; 192:223-30.
20. Amara A, Gall SL, Schwartz O et al. HIV coreceptor down-regulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J Exp Med 1997; 186:139-46.
21. Mack M, Luckow B, Nelson PJ et al. Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity. J Exp Med 1998; 187:1215-24.
22. Sauty A, Dziejman M, Taha RA, Iarossi AS, Neote K, Garcia-Zepeda EA, Hamid Q, Luster AD. The T cell-specific CXC chemokines IP-10, Mig, and I-TAC are expressed by activated human bronchial epithelial cells. J Immunol 1999; 162: 3549-58.
23. Miura M, Monta K, Kobayashi H, Hamilton TA, Burdick MD, Stricter RM, Fairchild RL. Monokine induced by IFN-γ is a dominant factor directing T cells into murine cardiac allografts during acute rejection. J Immunol 2001; 167: 3494-504.
24. Bowdish ME, Barr ML, Quardt SM et al. Evaluation of an oral CXCR3 antagonist in a rat model of acute cardiac allograft rejection. Am J Transplant 2003; s5:182.
25. Boehm U, Klamp T, Groot M, Howard JC. Cellular responses to interferon-gamma. Annu Rev Immunol 1997; 15:749-95.
26. Thai NL, Fu F, Qian S et al. Cytokine mRNA profiles in mouse orthotopic liver transplantation. Graft rejection is associated with augmented TH1 function. Transplantation 1995; 59:274-81.
27. Kobayashi H, Novick AC, Toma H, Fairchild RL. Chronic antagonism of Mig inhibits cellular infiltration and promotes survival of class II MHC disparate skin allografts. Transplantation 2002; 74:387-95.
28. Yun JJ, Fischbein MP, Whiting D et al. The role of MIG/CXCL9 in cardiac allograft vasculopathy. Am J Pathol 2002; 161:1307-13.
29. Belperio JA, Keane MP, Burdick MD, Lynch JP III, Xue YY, Li K, Ross DJ, Stricter RM. Critical role for CXCR3 chemokine biology in the pathogenesis bronchiolitis obliterans syndrome. J Immunol 2002; 169:1037-49.
30. Park MK, Amichay D, Love P et al. The CXC chemokine murine monokine induced by IFN-gamma (CXC chemokine ligand 9) is made by APCs, targets lymphocyte including activated B cells, and supports antibody responses to a bacterial pathogen in vivo. J Immunol 2002; 169:1433-43.
31. Loetscher P, Pellefrino A, Gong JH, Mattioli I, Loetscher M, Bardi G, Baggiolini M, Clark-Lewis I. The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10 are natural antagonists for CCR3. J Biol Chem 2001; 276:2986-91.