메뉴 건너뛰기




Volumn 53, Issue 5, 2004, Pages 375-382

Trials and tribulations of immunotherapy as a treatment option for patients with squamous cell carcinoma of the head and neck

Author keywords

Head and neck cancer; HNSCC; Immune; Immunosuppression; Immunotherapy

Indexed keywords

BCG VACCINE; CALCIFEDIOL; CD34 ANTIGEN; CISPLATIN; CYCLOOXYGENASE 2 INHIBITOR; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; FLUOROURACIL; FOLINIC ACID; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 6; MONOCLONAL ANTIBODY; PROSTAGLANDIN E2; TUMOR VACCINE; ANTINEOPLASTIC AGENT;

EID: 2342655015     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-003-0456-x     Document Type: Review
Times cited : (23)

References (91)
  • 1
    • 0033913754 scopus 로고    scopus 로고
    • A multi-institutional phase II study of BMS-182248-01 (BR96-doxorubicin conjugate) administered every 21 days in patients with advanced gastric adenocarcinoma
    • Ajani JA, Kelsen DP, Haller D, Hargraves K, Healey D (2000) A multi-institutional phase II study of BMS-182248-01 (BR96-doxorubicin conjugate) administered every 21 days in patients with advanced gastric adenocarcinoma. Cancer J 6:78-81
    • (2000) Cancer J , vol.6 , pp. 78-81
    • Ajani, J.A.1    Kelsen, D.P.2    Haller, D.3    Hargraves, K.4    Healey, D.5
  • 6
    • 0020334145 scopus 로고
    • 2 production by suppressor monocytes in head and neck cancer patients
    • 2 production by suppressor monocytes in head and neck cancer patients. Ann Surg 196:645-650
    • (1982) Ann Surg , vol.196 , pp. 645-650
    • Balch, C.M.1    Dougherty, P.A.2    Tilden, A.B.3
  • 8
    • 12244265457 scopus 로고    scopus 로고
    • + progenitor cells and dendritic cells to the site of tumor excision as the first step of an immunotherapeutic approach to target residual tumor cells
    • + progenitor cells and dendritic cells to the site of tumor excision as the first step of an immunotherapeutic approach to target residual tumor cells. J Immunother 26:31-40
    • (2003) J Immunother , vol.26 , pp. 31-40
    • Banich, J.C.1    Kolesiak, K.2    Young, M.R.3
  • 10
    • 0031868728 scopus 로고    scopus 로고
    • Anti-(epidermal growth factor) receptor monoclonal antibodies for the induction of antibody-dependent cell-mediated cytotoxicity against squamous cell carcinoma lines of the head and neck
    • Bier H, Hoffmann T, Haas I, van Lierop A (1998) Anti-(epidermal growth factor) receptor monoclonal antibodies for the induction of antibody-dependent cell-mediated cytotoxicity against squamous cell carcinoma lines of the head and neck. Cancer Immunol Immunother 46:167-173
    • (1998) Cancer Immunol Immunother , vol.46 , pp. 167-173
    • Bier, H.1    Hoffmann, T.2    Haas, I.3    Van Lierop, A.4
  • 11
    • 0035001584 scopus 로고    scopus 로고
    • Clinical trial with escalating doses of the antiepidermal growth factor receptor humanized monoclonal antibody EMD 72 000 in patients with advanced squamous cell carcinoma of the larynx and hypopharynx
    • Bier H, Hoffmann T, Hauser U, Wink M, Ochler M, Kovar A, Muser M, Knecht R (2001) Clinical trial with escalating doses of the antiepidermal growth factor receptor humanized monoclonal antibody EMD 72 000 in patients with advanced squamous cell carcinoma of the larynx and hypopharynx. Cancer Chemother Pharmacol 47:519-524
    • (2001) Cancer Chemother Pharmacol , vol.47 , pp. 519-524
    • Bier, H.1    Hoffmann, T.2    Hauser, U.3    Wink, M.4    Ochler, M.5    Kovar, A.6    Muser, M.7    Knecht, R.8
  • 13
    • 0037371233 scopus 로고    scopus 로고
    • Generation of vaccine-primed lymphocytes for the treatment of head and neck cancer
    • Chang AE, Li Q, Jiang G, Teknos TN, Chepeha DB, Bradford CR (2003) Generation of vaccine-primed lymphocytes for the treatment of head and neck cancer. Head Neck 25:198-209
    • (2003) Head Neck , vol.25 , pp. 198-209
    • Chang, A.E.1    Li, Q.2    Jiang, G.3    Teknos, T.N.4    Chepeha, D.B.5    Bradford, C.R.6
  • 15
  • 16
    • 0026442689 scopus 로고
    • Tumor necrosis factor-α-dependent production of reactive nitrogen intermediates mediates IFN-γ plus IL-2-induced murine macrophage tumoricidal activity
    • Cox GW, Melillo G, Chattopadhyay U, Mullet D, Fertel RH, Varesio L (1992) Tumor necrosis factor-α-dependent production of reactive nitrogen intermediates mediates IFN-γ plus IL-2-induced murine macrophage tumoricidal activity. J Immunol 149:3290-3296
    • (1992) J Immunol , vol.149 , pp. 3290-3296
    • Cox, G.W.1    Melillo, G.2    Chattopadhyay, U.3    Mullet, D.4    Fertel, R.H.5    Varesio, L.6
  • 17
    • 0026763177 scopus 로고
    • Administration of a prostaglandin synthetase inhibitor associated with an increased immune cell infiltrate in squamous cell carcinoma of the head and neck
    • Cross DS, Platt JL, Juhn SK, Bach FH, Adams GL (1992) Administration of a prostaglandin synthetase inhibitor associated with an increased immune cell infiltrate in squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 118:526-528
    • (1992) Arch Otolaryngol Head Neck Surg , vol.118 , pp. 526-528
    • Cross, D.S.1    Platt, J.L.2    Juhn, S.K.3    Bach, F.H.4    Adams, G.L.5
  • 18
    • 0035005295 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor in a combination gene therapy strategy for head and neck cancer
    • Day KV, Li D, Liu S, Guo M, O'Malley BW Jr (2001) Granulocyte-macrophage colony-stimulating factor in a combination gene therapy strategy for head and neck cancer. Laryngoscope 111:801-806
    • (2001) Laryngoscope , vol.111 , pp. 801-806
    • Day, K.V.1    Li, D.2    Liu, S.3    Guo, M.4    O'Malley Jr., B.W.5
  • 20
    • 0032947187 scopus 로고    scopus 로고
    • Where have all the T cells gone? Mechanisms of immune evasion by tumors
    • Finke J, Ferrone S, Frey A, Mufson A, Ochoa A (1999) Where have all the T cells gone? mechanisms of immune evasion by tumors. Immunol Today 20:158-160
    • (1999) Immunol Today , vol.20 , pp. 158-160
    • Finke, J.1    Ferrone, S.2    Frey, A.3    Mufson, A.4    Ochoa, A.5
  • 23
    • 0029893672 scopus 로고    scopus 로고
    • Dendritic cells in antitumor immune responses. II. Dendritic cells grown from bone marrow precursors, but not mature DC from tumor-bearing mice, are effective antigen carriers in the therapy of established tumors
    • Gabrilovich DI, Nadaf S, Corak J, Berzofsky JA, Carbone DP (1996) Dendritic cells in antitumor immune responses. II. Dendritic cells grown from bone marrow precursors, but not mature DC from tumor-bearing mice, are effective antigen carriers in the therapy of established tumors. Cell Immunol 170:111-119
    • (1996) Cell Immunol , vol.170 , pp. 111-119
    • Gabrilovich, D.I.1    Nadaf, S.2    Corak, J.3    Berzofsky, J.A.4    Carbone, D.P.5
  • 24
    • 0032400862 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo
    • Gabrilovich D, Ishida T, Oyama T, Ran S, Kravtsov V, Nadaf S, Carbone DP (1998) Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood 92:4150-4166
    • (1998) Blood , vol.92 , pp. 4150-4166
    • Gabrilovich, D.1    Ishida, T.2    Oyama, T.3    Ran, S.4    Kravtsov, V.5    Nadaf, S.6    Carbone, D.P.7
  • 28
    • 0346665674 scopus 로고    scopus 로고
    • Alloantigen gene therapy for head and neck cancer: Evaluation of animal models
    • Gleich LL, Li YQ, Li S, Gluckman JL, Stambrook PJ (2003) Alloantigen gene therapy for head and neck cancer: Evaluation of animal models. Head Neck 25:274-279
    • (2003) Head Neck , vol.25 , pp. 274-279
    • Gleich, L.L.1    Li, Y.Q.2    Li, S.3    Gluckman, J.L.4    Stambrook, P.J.5
  • 29
    • 0035994987 scopus 로고    scopus 로고
    • Tumor-associated antigens as possible targets for immune therapy in head and neck cancer: Comparative mRNA expression analysis of Rage and Gage genes
    • Gotte K, Usener D, Riedel F, Hormann K, Schadendorf D, Eichmuller S (2002) Tumor-associated antigens as possible targets for immune therapy in head and neck cancer: comparative mRNA expression analysis of RAGE and GAGE genes. Acta Otolaryngol 122:546-552
    • (2002) Acta Otolaryngol , vol.122 , pp. 546-552
    • Gotte, K.1    Usener, D.2    Riedel, F.3    Hormann, K.4    Schadendorf, D.5    Eichmuller, S.6
  • 30
    • 0033912368 scopus 로고    scopus 로고
    • Human leukocyte antigen class I allelic and haplotype loss in squamous cell carcinoma of the head and neck: Clinical and immunogenetic consequences
    • Grandis JR, Falkner DM, Melhem MF, Gooding WE, Drenning SD, Morel PA (2000) Human leukocyte antigen class I allelic and haplotype loss in squamous cell carcinoma of the head and neck: clinical and immunogenetic consequences. Clin Cancer Res 6:2794-2802
    • (2000) Clin Cancer Res , vol.6 , pp. 2794-2802
    • Grandis, J.R.1    Falkner, D.M.2    Melhem, M.F.3    Gooding, W.E.4    Drenning, S.D.5    Morel, P.A.6
  • 32
    • 0032952749 scopus 로고    scopus 로고
    • Peripheral blood mononuclear cell (PBMC) responsiveness in patients with head and neck cancer in relation to tumour stage and prognosis
    • Heimdal JH, Aarstad HJ, Klementsen B, Olofsson J (1999) Peripheral blood mononuclear cell (PBMC) responsiveness in patients with head and neck cancer in relation to tumour stage and prognosis. Acta Otolaryngol 119:281-284
    • (1999) Acta Otolaryngol , vol.119 , pp. 281-284
    • Heimdal, J.H.1    Aarstad, H.J.2    Klementsen, B.3    Olofsson, J.4
  • 33
    • 0037217371 scopus 로고    scopus 로고
    • + suppressor lymphocytes in the circulation of patients immunized against melanoma antigens
    • + suppressor lymphocytes in the circulation of patients immunized against melanoma antigens. J Immunother 26:85-93
    • (2003) J Immunother , vol.26 , pp. 85-93
    • Javia, L.R.1    Rosenberg, S.A.2
  • 34
    • 0033486007 scopus 로고    scopus 로고
    • T-cell priming by type-1 and type-2 polarized dendritic cells: The concept of a third signal
    • Kalinski P, Hilkens CMU, Wierenga EA, Kapsenberg ML (2000) T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunology Today 20:561-567
    • (2000) Immunology Today , vol.20 , pp. 561-567
    • Kalinski, P.1    Hilkens, C.M.U.2    Wierenga, E.A.3    Kapsenberg, M.L.4
  • 37
    • 0038274027 scopus 로고    scopus 로고
    • Identification of NY-ESO-1, MAGE-1, and MAGE-3 in head and neck squamous cell carcinoma
    • Kienstra MA, Neel HB, Strome SE, Roche P (2003) Identification of NY-ESO-1, MAGE-1, and MAGE-3 in head and neck squamous cell carcinoma. Head Neck 25:457-463
    • (2003) Head Neck , vol.25 , pp. 457-463
    • Kienstra, M.A.1    Neel, H.B.2    Strome, S.E.3    Roche, P.4
  • 39
    • 9244242518 scopus 로고    scopus 로고
    • Evaluation of multi skin test in colorectal cancer patients and effects of serum immunosuppressive factor and cytokine production of peripheral mononuclear cells
    • Kondo Y, Uchino J, Sawaguchi Y, Shirato H, Gondo H, Hase T, Saito I, Higashi T, Hosokawa M, Kobayashi H (1996) Evaluation of multi skin test in colorectal cancer patients and effects of serum immunosuppressive factor and cytokine production of peripheral mononuclear cells. Am J Clin Oncol 19:159-163
    • (1996) Am J Clin Oncol , vol.19 , pp. 159-163
    • Kondo, Y.1    Uchino, J.2    Sawaguchi, Y.3    Shirato, H.4    Gondo, H.5    Hase, T.6    Saito, I.7    Higashi, T.8    Hosokawa, M.9    Kobayashi, H.10
  • 40
    • 0028870475 scopus 로고
    • + helper/killer T cell phenomenon. Selective induction of Th1 helper/killer T cells and application to tumor immunotherapy
    • + helper/killer T cell phenomenon. Selective induction of Th1 helper/killer T cells and application to tumor immunotherapy. J Immunol 154:1777-1785
    • (1995) J Immunol , vol.154 , pp. 1777-1785
    • Kuge, S.1    Miura, Y.2    Nakamura, Y.3    Mitomi, T.4    Habu, S.5    Nishimura, T.6
  • 43
    • 0034760924 scopus 로고    scopus 로고
    • 3 treatment to diminish suppressor cells in head and neck cancer patients
    • 3 treatment to diminish suppressor cells in head and neck cancer patients. Human Immunol 62:1282-1293
    • (2001) Human Immunol , vol.62 , pp. 1282-1293
    • Lathers, D.M.R.1    Achille, N.J.2    Young, M.R.I.3
  • 44
    • 0034760591 scopus 로고    scopus 로고
    • Combination nonviral interleukin 2 and interleukin 12 gene therapy for head and neck squamous cell carcinoma
    • Li D, Shugert E, Guo M, Bishop JS, O'Malley BW Jr (2001) Combination nonviral interleukin 2 and interleukin 12 gene therapy for head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 127:1319-1324
    • (2001) Arch Otolaryngol Head Neck Surg , vol.127 , pp. 1319-1324
    • Li, D.1    Shugert, E.2    Guo, M.3    Bishop, J.S.4    O'Malley Jr., B.W.5
  • 45
    • 0034652619 scopus 로고    scopus 로고
    • Dendritic cell-based immunotherapy of prostate cancer: Immune monitoring of a phase II clinical trial
    • Lodge PA, Jones LA, Bader RA, Murphy GP, Salgaller ML (2000) Dendritic cell-based immunotherapy of prostate cancer: Immune monitoring of a phase II clinical trial. Cancer Res 60:829-833
    • (2000) Cancer Res , vol.60 , pp. 829-833
    • Lodge, P.A.1    Jones, L.A.2    Bader, R.A.3    Murphy, G.P.4    Salgaller, M.L.5
  • 46
    • 0037740991 scopus 로고    scopus 로고
    • A pilot study of edrecolomab (Panorex, 17-1A antibody) and capecitabine in patients with advanced or metastatic adenocarcinoma
    • Makower D, Sparano JA, Wadler S, Fehn K, Landau L, Wissel P, Versola M, Mani S (2003) A pilot study of edrecolomab (Panorex, 17-1A antibody) and capecitabine in patients with advanced or metastatic adenocarcinoma. Cancer Invest 21:177-184
    • (2003) Cancer Invest , vol.21 , pp. 177-184
    • Makower, D.1    Sparano, J.A.2    Wadler, S.3    Fehn, K.4    Landau, L.5    Wissel, P.6    Versola, M.7    Mani, S.8
  • 47
    • 0037489569 scopus 로고    scopus 로고
    • Cure of an established nonimmunogenic tumor, SCC VII, with a novel interleukin 12-based immunotherapy regimen in C3H mice
    • Mandpe AH, Tsung K, Norton JA (2003) Cure of an established nonimmunogenic tumor, SCC VII, with a novel interleukin 12-based immunotherapy regimen in C3H mice. Arch Otolaryngol Head Neck Surg 129:786-792
    • (2003) Arch Otolaryngol Head Neck Surg , vol.129 , pp. 786-792
    • Mandpe, A.H.1    Tsung, K.2    Norton, J.A.3
  • 48
    • 0027034108 scopus 로고
    • Cytokine expression by head and neck squamous cell carcinomas
    • Mann EA, Spiro JD, Chen LL, Kreutzer DL (1992) Cytokine expression by head and neck squamous cell carcinomas. Am J Surg 164:567-573
    • (1992) Am J Surg , vol.164 , pp. 567-573
    • Mann, E.A.1    Spiro, J.D.2    Chen, L.L.3    Kreutzer, D.L.4
  • 50
    • 0037105694 scopus 로고    scopus 로고
    • Adenovirus infection enhances dendritic cell immunostimulatory properties and induces natural killer and T-cell-mediated tumor protection
    • Miller G, Lahrs S, Pillarisetty VG, Shah AB, DeMatteo RP (2002) Adenovirus infection enhances dendritic cell immunostimulatory properties and induces natural killer and T-cell-mediated tumor protection. Cancer Res 62:5260-5266
    • (2002) Cancer Res , vol.62 , pp. 5260-5266
    • Miller, G.1    Lahrs, S.2    Pillarisetty, V.G.3    Shah, A.B.4    DeMatteo, R.P.5
  • 51
    • 0037105385 scopus 로고    scopus 로고
    • Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function
    • Miller G, Pillarisetty VG, Shah AB, Lahrs S, Xing Z, DeMatteo RP (2002) Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function. J Immunol 169:2875-2885
    • (2002) J Immunol , vol.169 , pp. 2875-2885
    • Miller, G.1    Pillarisetty, V.G.2    Shah, A.B.3    Lahrs, S.4    Xing, Z.5    DeMatteo, R.P.6
  • 56
    • 0033568001 scopus 로고    scopus 로고
    • Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo
    • Ohm JE, Shurin MR, Esche C, Lotze MT, Carbone DP, Gabrilovich DI (1999) Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo. J Immunol 163:3260-3268
    • (1999) J Immunol , vol.163 , pp. 3260-3268
    • Ohm, J.E.1    Shurin, M.R.2    Esche, C.3    Lotze, M.T.4    Carbone, D.P.5    Gabrilovich, D.I.6
  • 58
    • 0029047916 scopus 로고
    • Ineffective immune enhancement by IL-12 in tumor-bearing mice whose immune depression is mediated by suppressive granulocyte-macrophage progenitor cells
    • Prechel MM, Lozano Y, Wright MA, Ihm J, Young MRI (1995) Ineffective immune enhancement by IL-12 in tumor-bearing mice whose immune depression is mediated by suppressive granulocyte-macrophage progenitor cells. Cancer Lett 92:235-242
    • (1995) Cancer Lett , vol.92 , pp. 235-242
    • Prechel, M.M.1    Lozano, Y.2    Wright, M.A.3    Ihm, J.4    Young, M.R.I.5
  • 60
    • 0032403180 scopus 로고    scopus 로고
    • Absent or low expression of the zeta chain in T cells at the tumor site correlates with poor survival in patients with oral carcinoma
    • Reichert TE, Day R, Wagner EM, Whiteside TL (1998) Absent or low expression of the zeta chain in T cells at the tumor site correlates with poor survival in patients with oral carcinoma. Cancer Res 58:5344-5347
    • (1998) Cancer Res , vol.58 , pp. 5344-5347
    • Reichert, T.E.1    Day, R.2    Wagner, E.M.3    Whiteside, T.L.4
  • 61
    • 0037179894 scopus 로고    scopus 로고
    • Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas
    • Rhee CS, Sen M, Lu D, Wu C, Leoni L, Rubin J, Corr M, Carson DA (2002) Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas. Oncogene 21:6598-6605
    • (2002) Oncogene , vol.21 , pp. 6598-6605
    • Rhee, C.S.1    Sen, M.2    Lu, D.3    Wu, C.4    Leoni, L.5    Rubin, J.6    Corr, M.7    Carson, D.A.8
  • 64
    • 0035451831 scopus 로고    scopus 로고
    • Predominant Th2/Tc2 polarity of tumor-infiltrating lymphocytes in human cervical cancer
    • Sheu BC, Lin RH, Lien HC, Ho HN, Hsu SM, Huang SC (2001) Predominant Th2/Tc2 polarity of tumor-infiltrating lymphocytes in human cervical cancer. J Immunol 167:2972-2978
    • (2001) J Immunol , vol.167 , pp. 2972-2978
    • Sheu, B.C.1    Lin, R.H.2    Lien, H.C.3    Ho, H.N.4    Hsu, S.M.5    Huang, S.C.6
  • 66
    • 0032998308 scopus 로고    scopus 로고
    • Paclitaxel-based chemotherapy for recurrent and/or metastatic head and neck squamous cell carcinoma: Current and future directions
    • Shin DM, Lippman SM (1999) Paclitaxel-based chemotherapy for recurrent and/or metastatic head and neck squamous cell carcinoma: current and future directions. Semin Oncol 26:100-105
    • (1999) Semin Oncol , vol.26 , pp. 100-105
    • Shin, D.M.1    Lippman, S.M.2
  • 68
    • 0035292790 scopus 로고    scopus 로고
    • IL-6 and IFN-γ regulation of IL-10 production by human colon carcinoma cells
    • Suzuki S, Mita S, Kamohara H, Sakamoto K, Ishiko T, Ogawa M (2001) IL-6 and IFN-γ regulation of IL-10 production by human colon carcinoma cells. Int J Oncol 18:581-586
    • (2001) Int J Oncol , vol.18 , pp. 581-586
    • Suzuki, S.1    Mita, S.2    Kamohara, H.3    Sakamoto, K.4    Ishiko, T.5    Ogawa, M.6
  • 69
    • 0034114552 scopus 로고    scopus 로고
    • IL-12- and IL-2-induced tumor regression in a new murine model of oral squamous-cell carcinoma is promoted by expression of the CD80 co-stimulatory molecule and interferon-γ
    • Thomas GR, Chen Z, Enamorado I, Bancroft C, Van Waes C (2000) IL-12- and IL-2-induced tumor regression in a new murine model of oral squamous-cell carcinoma is promoted by expression of the CD80 co-stimulatory molecule and interferon-γ. Int J Cancer 86:368-374
    • (2000) Int J Cancer , vol.86 , pp. 368-374
    • Thomas, G.R.1    Chen, Z.2    Enamorado, I.3    Bancroft, C.4    Van Waes, C.5
  • 73
    • 0023839731 scopus 로고
    • Indomethacin sensitive suppressor-cell activity in head and neck cancer patients. The role of the adherent mononuclear cell
    • Wanebo HJ, Riley T, Karz D, Pace RC, Johns ME, Cantrell RW (1988) Indomethacin sensitive suppressor-cell activity in head and neck cancer patients. The role of the adherent mononuclear cell. Cancer 61:462-474
    • (1988) Cancer , vol.61 , pp. 462-474
    • Wanebo, H.J.1    Riley, T.2    Karz, D.3    Pace, R.C.4    Johns, M.E.5    Cantrell, R.W.6
  • 76
    • 0037341335 scopus 로고    scopus 로고
    • Tumour-induced polarization of tumour vaccine-draining lymph node T cells to a type 1 cytokine profile predicts inherent strong immunogenicity of the tumour and correlates with therapeutic efficacy in adoptive transfer studies
    • Winter H, Hu HM, Poehlein CH, Huntzicker E, Osterholzer JJ, Bashy J, Lashley D, Lowe B, Yamada J, Alvord G, Urba WJ, Fox BA (2003) Tumour-induced polarization of tumour vaccine-draining lymph node T cells to a type 1 cytokine profile predicts inherent strong immunogenicity of the tumour and correlates with therapeutic efficacy in adoptive transfer studies. Immunology 108:409-419
    • (2003) Immunology , vol.108 , pp. 409-419
    • Winter, H.1    Hu, H.M.2    Poehlein, C.H.3    Huntzicker, E.4    Osterholzer, J.J.5    Bashy, J.6    Lashley, D.7    Lowe, B.8    Yamada, J.9    Alvord, G.10    Urba, W.J.11    Fox, B.A.12
  • 77
    • 0031435653 scopus 로고    scopus 로고
    • Reversal of tumor-induced immunosuppression: A new approach to cancer therapy
    • Wojtowiczpraga S (1997) Reversal of tumor-induced immunosuppression: a new approach to cancer therapy. J Immunother 20:165-177
    • (1997) J Immunother , vol.20 , pp. 165-177
    • Wojtowiczpraga, S.1
  • 79
    • 0026552282 scopus 로고
    • Tumor-reactive T-cells accumulate in lung cancer tissues but fail to respond due to tumor cell-derived factor
    • Yoshino I, Yano T, Murata M, Ishida T, Sugimachi K, Kimura G (1992) Tumor-reactive T-cells accumulate in lung cancer tissues but fail to respond due to tumor cell-derived factor. Cancer Res 52:775-781
    • (1992) Cancer Res , vol.52 , pp. 775-781
    • Yoshino, I.1    Yano, T.2    Murata, M.3    Ishida, T.4    Sugimachi, K.5    Kimura, G.6
  • 81
    • 0032973003 scopus 로고    scopus 로고
    • Myeloid progenitor cells mediate immune suppression in patients with head and neck cancers
    • Young MR, Lathers DM (1999) Myeloid progenitor cells mediate immune suppression in patients with head and neck cancers. Int J Immunopharmacol 21:241-252
    • (1999) Int J Immunopharmacol , vol.21 , pp. 241-252
    • Young, M.R.1    Lathers, D.M.2
  • 82
    • 0024553692 scopus 로고
    • Effects of fish oil diets on prostaglandin-dependent and myelopoiesis-associated immune suppressor mechanisms of mice bearing metastatic Lewis lung carcinoma tumors
    • Young MR, Young ME (1989) Effects of fish oil diets on prostaglandin-dependent and myelopoiesis-associated immune suppressor mechanisms of mice bearing metastatic Lewis lung carcinoma tumors. Cancer Res 49:1931-1936
    • (1989) Cancer Res , vol.49 , pp. 1931-1936
    • Young, M.R.1    Young, M.E.2
  • 84
    • 0029833732 scopus 로고    scopus 로고
    • Mechanisms of immune suppression in patients with head and neck cancer: Influence on the immune infiltrate of the cancer
    • Young MRI, Wright MA, Lozano Y, Matthews JP, Benefield J, Prechel MM (1996) Mechanisms of immune suppression in patients with head and neck cancer: influence on the immune infiltrate of the cancer. Int J Cancer 67:333-338
    • (1996) Int J Cancer , vol.67 , pp. 333-338
    • Young, M.R.I.1    Wright, M.A.2    Lozano, Y.3    Matthews, J.P.4    Benefield, J.5    Prechel, M.M.6
  • 85
    • 0030059765 scopus 로고    scopus 로고
    • Suppression of T cell proliferation by tumor-induced granulocyte- macrophage progenitor cells producing transforming growth factor-β and nitric oxide
    • Young MRI, Wright MA, Matthews JP, Malik I, Prechel M (1996) Suppression of T cell proliferation by tumor-induced granulocyte-macrophage progenitor cells producing transforming growth factor-β and nitric oxide. J Immunol 156:1916-1922
    • (1996) J Immunol , vol.156 , pp. 1916-1922
    • Young, M.R.I.1    Wright, M.A.2    Matthews, J.P.3    Malik, I.4    Prechel, M.5
  • 87
    • 0031570886 scopus 로고    scopus 로고
    • + cells within human head and neck squamous cell carcinomas
    • + cells within human head and neck squamous cell carcinomas. J Immunol 159:990-996
    • (1997) J Immunol , vol.159 , pp. 990-996
    • Young, M.R.I.1    Wright, M.A.2    Pandit, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.