Stimulation of immune suppressive CD34+ cells from normal bone marrow by lewis lung carcinoma tumors

Cancer Immunology Immunotherapy

Volumn 46, Issue 5, 1998, Pages 253-260

  Wright, Mark A ^a   Wiers, Kristina ^b   Vellody, Kishore ^a   Djordjevic, Dragana ^a   Young, M Rita I ^a,b  

^a VA Hospital   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Cancer; CD34+ cells; Immune suppressor cells; Natural suppressor cells; Tumor

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; LEWIS CARCINOMA; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD34; BONE MARROW CELLS; CALCITRIOL; CARCINOMA, LEWIS LUNG; CELL DIFFERENTIATION; CELLS, CULTURED; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; IMMUNE TOLERANCE; MICE; MICE, INBRED C57BL; TUMOR CELLS, CULTURED;

EID: 0031826383     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050485     Document Type: Article

References (45)

1. Alexander JP, Kudoh S, Melsop KA, Hamilton TA, Edinger MG, Tubbs RR, Sica D, Tuason L, Klein E, Budowski RM, Finke JH (1993) T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors. Cancer Res 53:1380
2. Alleva DG, Burger CJ, Elgert KD (1994) Tumour growth causes suppression of autoreactive T-cell proliferation by disrupting macrophage responsiveness to interferon-gamma. Scand J Immunol 39:31
3. 2. J Immunol 153:1674
4. Alleva DG, Walker TM, Elgert KD (1995) Induction of macrophage suppressor activity by fibrosarcoma-derived transforming growth factor-β1: contrasting effects on resting and activated macrophages J Leukoc Biol 57:919
5. Almawi WY, Dolphin PJ, Thies RL, McMaster WR, Levy JG, Pope BL (1988) Suppressor cell-inducing factor: a new lymphokine secreted by natural suppressor cell line with natural cytotoxic activity. I. Purification to apparent homogeneity and initial characterization of suppressor cell-inducing factor. J Immunol 141:2529-2535
6. Berdel WE, Danhauser-Riedl S, Oberberg D, Zafferani M (1992) Effects of hematopoietic growth factors on malignant nonhematopoietic cells. Semin Oncol 19:41
7. + natural suppressor cells on IL-2 and IL-4 utilization in MLR. Transplantation 58:1096
8. Cox GW, Melillo G, Chattopadhyay U, Mullet D, Fertel RH, Varesio L (1992) Tumor necrosis factor-α-dependent production of reactive nitrogen intermediates mediates IFNγ plus IL-2-induced murine macrophage tumoricidal activity. J Immunol 149:3290
9. deBruijn MF, Slicker WA, Loo JC van der, Voerman JS, van EW, Leenen PJ (1994) Distinct mouse bone marrow macrophage precursors identified by differential expression of ER-MP12 and ER-MP20 antigens. Eur J Immunol 24:2279
10. 3 in induction of myeloid differentiation of human leukemic cell lines. J Leukoc Biol 51:237
11. Field EH, Becker GC (1992) Blocking of mixed lymphocyte reaction by spleen cells from total lymphoid-irradiated mice involves interruption of the IL-2 pathway. J Immunol 148:354
12. + cells. Int J Cancer 73:663
13. Hoskin DW, Bowser DA, Brooks-Kaiser JC (1992) Soybean agglutinin-positive natural suppressor cells in mouse bone marrow inhibit interleukin 2 production and utilization in mixed lymphocyte reactions. J Leukoc Biol 51:649
14. Inge TH, Hoover SK, Frank JL, Kawabata TT, Bethke KP, Bear HD (1992) Enhancement of cytotoxic T lymphocyte growth from spleens of P815-tumor-bearing host mice with mafosfamide. Cancer Immunol Immunother 35:119
15. Ino K, Singh RK, Talmadge JE (1997) Monocytes from mobilized stem cells inhibit T cell function. J Leukoc Biol 61:583
16. Joraschkewitz M, Depenbrock H, Freund M, Erdmann G, Meyer H-J, De Riese W, Neukam D, Hanauske U, Krumwieh M, Poliwoda H, Hanauske A-R (1992) Effects of cytokines on in vitro colony formation of primary human tumour specimens. Eur J Cancer 26:1070
17. Koyama S, Fukao K (1994) Phenotypic analysis of nylon-wool-adherent suppressor cells that inhibit the effector process of tumour cell lysis by lymphokine-activated killer cells in patients with advanced gastric carcinoma. J Cancer Res Clin Oncol 120:240
18. + helper/killer T cell phenomenon. Selective induction of Th1 helper/killer T cells and application to tumor immunotherapy. J Immunol 154:1777
19. Lang SH, Miller WR, Duncan W, Habib FK (1994) Production and response of human prostate cancer cell lines to granulocyte macrophage-colony stimulating factor. Int J Cancer 59:235
20. Leenen PJ, de BM, Voerman JS, Campbell PA, van EW (1994) Markers of mouse macrophage development detected by monoclonal antibodies. J Immunol Methods 174:5
21. van der Loo JC, Slieker WA, Kieboom D, Ploemacher RL (1995) Identification of hematopoietic stem cell subsets on the basis of their primitiveness using antibody ER-MP12. Blood 85:952
22. Maeda N, Sagara Y (1993) Analysis of immunosuppressive mechanism to cytotoxic T lymphocyte generation in patients with advanced cancer. Asia Oceana J Obstet Gynaecol 19:309
23. Maier T, Holda JH, Claman HN (1989) Murine natural suppresssor cells in the newborn,in bone marrow, and after cyclophosphamide. Genetic variations and dependence on IFNγ. J Immunol 143: 491-498
24. Moore SC, Theus SA, Barnett JB, Soderberg LS (1992) Cytokine regulation of bone marrow natural suppressor cell activity in the suppression of lymphocyte function. Cell Immunol 141:398
25. Mizoguchi H, O'Shea JJ, Longo DL, Loeffler CM, McVicar DW, Ochoa AC (1992) Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice. Science 258:1795
26. 2-dependem and -independent immune suppressor cells by tumor-derived GM-CSF and M-CSF. J Leukoc Biol 53:86
27. Pavel P, Halapi E, Pisa EK, Gerdin E, Hising C, Bucht A, Gerdin B, Kiessling R (1992) Selective expression of interleukin 10, interferon γ, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies. Proc Natl Acad Sci USA 89:7708
28. Prechel MM, Lozano Y, Wright MA, Ihm J, Young MRI (1995) Ineffective immune enhancement by IL-12 in tumor-bearing mice whose immune depression is mediated by suppressive granulocyte-macrophage progenitor cells. Cancer Lett 92:235
29. Sahasrabudhe DM, Dusel JC (1994) Effect of murine interferon α/β on tumour-induced suppressor function. Cancer Immunol Immunother 39:360
30. Sawyers CL, Golde DW, Quan S, Nimer SD (1992) Production of granulocyte-macrophage colony-stimulating factor in two patients with lung cancer, leukocytosis, and eosinophilia. Cancer 69:1342
31. Schmidt-Pak A, Ip G, Wright MA, Young MRI (1995) Treating tumor-bearing mice with low dose interferon-γ plus tumor necrosis factor-α to diminish immune suppressive granulocyte-macrophage progenitor cells increases responsiveness to IL-2 immunotherapy. Cancer Res 55:885
32. Schmidt-Wolf IG, Dejbakhsh-Jones S, Ginzton N, Greenberg P, Strober S (1992) T-cell subsets and suppressor cells in human bone marrow. Blood 80:3242
33. 3-induced terminal monocytic differentiation of human leukemic cell lines. J Immunol 150:2418
34. Vujanovic NL, Yasumura S, Hirabayashi H, Lin W, Watkins S, Herberman RB, Whiteside TL (1995) Antitumor activities of subsets of human IL-2-activated natural killer cells in solid tissues. J Immunol 154:281
35. 3 activates T cells of tumor bearers through protein phosphatase-2A. Cancer Immunol Immunother 44:97
36. Young MRI, Wright MA (1992) Myelopoiesis-associated immune suppressor cells in mice bearing metastatic Lewis lung carcinoma tumors: interferon-γ plus tumor necrosis factor-α synergistically reduce immune suppressor and tumor growth-promoting activities of bone marrow cells, and diminish tumor recurrence and metastasis. Cancer Res 52:6335
37. Young MRI, Young ME, Wright MA (1990) Stimulation of immune suppressive bone marrow cells by colony stimulating factors. Exp Hematol 18:806
38. Young MRI, Lozano Y, Coogan M, Wright MA, Young ME, Bagash JM (1992) Stimulation of the metastatic properties of Lewis-lung-carcinoma cells by autologous granulocyte-macrophage colony-stimulating factor. Int J Cancer 50:628
39. 3 plus γ-interferon blocks lung tumor production of granulocyte-macrophage colony-stimulating factor and induction of immunosuppressor cells. Cancer Res 53:6006
40. + tumor-infiltrating lymphocytes after eliminating immune suppressive granulocyte-macrophage progenitor cells with low doses of interferon-γ plus tumor necrosis factor-α. Cancer Immunol Immunother 38:9
41. 3 diminishes tumor-induced myelopoiesis and associated immune suppression, and reduces tumor metastasis and recurrence. Cancer Immunol Immunother 41:37
42. + cells in cancers that secrete granulocyte-macrophage colony-stimulating factor. Clin Cancer Res 1:95
43. Young MRI, Wright MA, Matthews JP, Malik I, Prechel M (1996) Suppression of T cell proliferation by tumor-induced granulocyte-macrophage progenitor cells producing transforming growth factor-β and nitric oxide. J Immunol 156:1916
44. + cells within human head and neck squamous cell carcinomas. J Immunol 159:990
45. Yoshino I, Yano T, Murata M, Ishida T, Sugimachi K, Kimura G (1992) Tumor-reactive T-cells accumulate in lung cancer tissues but fail to respond due to tumor cell-derived factor. Cancer Res 52:775