Heparan sulphate proteoglycans modulate fibroblast growth factor-2 binding through a lipid raft-mediated mechanism

Biochemical Journal

Volumn 379, Issue 2, 2004, Pages 331-341

  Chu, Chia Lin ^a   Buczek Thomas, Jo Ann ^a   Nugent, Matthew A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cholesterol; FGF (fibroblast growth factor); Heparan sulphate; Triton X 100 insolubility

Indexed keywords

ACTIVATION ANALYSIS; CELLS; CHOLESTEROL; CONCENTRATION (PROCESS); LIPIDS; MUSCLE; PROTEINS; SENSITIVITY ANALYSIS;

GROWTH FACTOR; LIPID RAFTS; SIGNAL TRANSDUCTION; STEROL-BINDING AGENTS;

BIOCHEMISTRY;

CHOLESTEROL; FIBROBLAST GROWTH FACTOR 2; HEPARAN SULFATE; HEPARIN LYASE; LIPID; PROTEIN KINASE C ALPHA; PROTEOGLYCAN;

ANIMAL CELL; ARTICLE; CELL DISRUPTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; DISSOCIATION; FRACTIONATION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; SOLUBILITY; VASCULAR SMOOTH MUSCLE;

ANIMALS; BETA-CYCLODEXTRINS; BINDING SITES; CATTLE; CYCLODEXTRINS; FIBROBLAST GROWTH FACTOR 2; FILIPIN; HEPARAN SULFATE PROTEOGLYCANS; MEMBRANE MICRODOMAINS; MUSCLE, SMOOTH, VASCULAR; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEOGLYCANS;

ANIMALIA;

EID: 2342633787     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031082     Document Type: Article

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