Time course of cellular proliferation, intimal hyperplasia, and remodeling following angioplasty in monkeys with established atherosclerosis: A nonhuman primate model of restenosis

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 16, Issue 1, 1996, Pages 34-43

  Geary, Randolph L ^a   Williams, J Koudy ^a   Golden, Deborah ^a   Brown, Deanna G ^a   Benjamin, Marshall E ^a   Adams, Michael R ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

angioplasty; cellular proliferation; Macaca fascicularis; remodeling; restenosis

Indexed keywords

BROXURIDINE;

ANGIOPLASTY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHERECTOMY; ATHEROSCLEROSIS; BYPASS SURGERY; CELL PROLIFERATION; ENDARTERECTOMY; HEART VENTRICLE REMODELING; IMMUNOHISTOCHEMISTRY; MONKEY; NONHUMAN; PRIORITY JOURNAL; RESTENOSIS; SMOOTH MUSCLE CONTRACTION; STATISTICAL ANALYSIS; STENT;

EID: 0030029723     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.16.1.34     Document Type: Article

References (35)

1. Detre K, Holubkov R, Kelsey S, Bourassa M, Williams D, Holmes D Jr. Dorros G, Faxon D, Myler R, Kent K, Cowley M, Cannon R, Robertson T, NHLBI Percutaneous Transluminal Coronary Angioplasty Registry. One-year follow-up results of the 1985-1986 National Heart, Lung, and Blood Institute's Percutaneous Transluminal Coronary Angioplasty Registry. Circulation. 1989;80:421-428.
2. Kitazume H, Kubo I, Iwama T, Ageishi Y. Long-term angiographic follow-up of lesions patent 6 months after percutaneous coronary angioplasty. Am Heart J. 1995;129:441-444.
3. Clowes AW, Karnovsky MJ. Suppression by heparin of smooth muscle cell proliferation in injured arteries. Nature. 1977;265: 625-626.
4. Powell JS, Clozel JP, Muler RKM, Kuhn H, Hefti F, Hosang M, Baumgartner HR. Inhibitors of angiotensin-converting enzyme prevent myointimal proliferation after vascular injury. Science. 1989;245:186-188.
5. Faxon DP, Spiro TE, Minor S, Coté G, Douglas J, Gottlieb R, Califf R, Dorosti K, Topol E, Gordon JB, Ohmen M, ERA Investigators. Low molecular weight heparin in prevention of restenosis after angioplasty: results of Enoxaparin Restenosis (ERA) Trial. Circulation. 1994;90:908-914.
6. Lehman KG, Doria RJ, Feuer JM, Hall PX, Hoang DT. Paradoxical increase in restenosis rate with chronic heparin use: final results of a randomized trial. J Am Coll Cardiol. 1991;17:181. Abstract.
7. MERCATOR Study Group. Does the new angiotensin converting enzyme inhibitor cilazapril prevent restenosis after percutaneous transluminal coronary angioplasty? Results of the MERCATOR Study: a multicenter, randomized, double-blind placebo-controlled trial. Circulation. 1992;86:100-110.
8. Faxon DP. Effect of high dose angiotensin-converting enzyme inhibition on restenosis: final results of the MARCATOR Study, a multicenter, double-blind, placebo-controlled trial of cilazapril. J Am Coll Cardiol. 1995;25:362-369.
9. Geary RL, Koyama N, Wang TW, Vergel S, Clowes AW. Failure of heparin to inhibit intimai hyperplasia in injured baboon arteries: the role of heparin-sensitive and heparin-insensitive pathways in the stimulation of smooth muscle cell migration and proliferation. Circulation. 1995;91:2972-2981.
10. O'Brien ER, Alpers CE, Stewart DK, Ferguson M, Tran N, Gordon D, Benditt EP, Hinohara T, Simpson JB, Schwartz SM. Proliferation in primary and restenotic coronary atherectomy tissue: implications for antiproliferative therapy. Circ Res. 1993;73: 223-231.
11. Kakuta T, Currier JW, Haudenschild CC, Ryan TJ, Faxon DP. Differences in compensatory vessel enlargement, not intimai formation, account for restenosis after angioplasty in the hypercholesterolemic rabbit model. Circulation. 1994;89:2809-2815.
12. Post MJ, Borst C, Kuntz RE. The relative importance of arterial remodeling compared with intimai hyperplasia in lumen renarrowing after balloon angioplasty: a study in the normal rabbit and the hypercholesterolemic Yucatan micropig. Circulation. 1994;89: 2816-2821.
13. Jackson CL. Animal models of restenosis. Trends Cardiovasc Med. 1994;4:122-130.
14. Beere PA, Glagov S, Zarins CK. Experimental atherosclerosis at the carotid bifurcation of the cynomolgus monkey: localization, compensatory enlargement, and the sparing effect of lowered heart rate. Arterioscler Thromb. 1992;12:1245-1253.
15. Zarins CK, Zatina MA, Giddens DP, Ku DN, Glagov S. Shear stress regulation of artery lumen diameter in experimental atherogenesis. J Vasc Surg. 1987;5:413-420.
16. Clarkson TB, Prichard RW, Morgan TM, Petrick GS, Potvin-Klein K. Remodeling of coronary arteries in human and nonhuman primates. JAMA. 1994;271:289-294.
17. Clarkson TB, Bond MG, Bullock BC, McLaughlin KJ, Sawyer JK. A study of atherosclerosis regression in Macaca mulatto, V: changes in abdominal aorta and carotid and coronary arteries from animals with atherosclerosis induced for 38 months and then regressed for 24 or 48 months at plasma cholesterol concentrations of 300 or 200 mg/dL. Exp Mol Pathol. 1984;41:96-118.
18. Sasahara M, Raines EW, Chait A, Carew TE, Steinberg D, Wahl PW, Ross R. Inhibition of hypercholesterolemia-induced athero-sclerosis in the nonhuman primate by probucol, I: is the extent of atherosclerosis related to resistance of LDL to oxidation. J Clin Invest. 1994;94:155-164.
19. Strong JP, Bhattacharyya AK, Eggen DA, Stary HC, Malcom GT, Newman WP III, Restrepo C. Long-term induction and regression of diet-induced atherosclerotic lesions in rhesus monkeys, II: morphometric evaluation of lesions by light microscopy in coronary and carotid arteries. Arterioscler Thromb. 1994;14:2007-2016.
20. Ellis SG, Roubin GS, Wilentz J, Douglas JS, King SB. Effect of 18-to 24-hour heparin administration for prevention of restenosis after uncomplicated coronary angioplasty. Am Heart J. 1989;117:777-782.
21. Currier JW, Faxon DP. Restenosis after percutaneous transluminal coronary angioplasty: have we been aiming at the wrong target? J Am Coll Cardiol. 1995;25:516-520.
22. Ueda M, Becker AE, Tsukada T, Numano F, Fujimoto T. Fibro-cellular tissue response after percutaneous transluminal coronary angioplasty: an immunocytochemical analysis of the cellular composition. Circulation. 1991;83:1327-1332.
23. Jain SP, Jain A, Collins TJ, Ramee SR, White CJ. Predictors of restenosis: a morphometric and quantitative evaluation by intravascular ultrasound. Am Heart J. 1994;128:664-673.
24. De Groote P, Bauters C, McFadden EP, Lablanche J-M, Leroy F, Bertrand ME. Local lesion-related factors and restenosis after coronary angioplasty: evidence from a quantitative angiographic study in patients with unstable angina undergoing double-vessel angioplasty. Circulation. 1995;91:968-972.
25. Losordo DW, Rosenfield K, Pieczek A, Baker K, Harding M, Isner JM. How does angioplasty work? Serial analysis of human iliac arteries using intravascular ultrasound. Circulation. 1992;86:1845-1858.
26. Jamal A, Bendeck M, Langille BL. Structural changes and recovery of function after arterial injury. Arterioscler Thromb. 1992;12: 307-317.
27. Hanson SR, Powell JS, Dodson T, Lumsden A, Kelly AB, Anderson JS, Clowes AW, Harker LA. Effects of angiotensin converting enzyme inhibition with cilazapril on intimal hyperplasia in injured arteries and vascular grafts in the baboon. Hypertension. 1991; 18(suppl II):II-70-II-76.
28. Pickering JG, Weir L, Jekanowski J, Kearney MA, Isner JM. Proliferative activity in peripheral and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization. J Clin Invest. 1993;91:1469-1480.
29. Glagov S, Weisenberg E, Zarins CK, Stankunavicius R, Kollettis GJ. Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med. 1987;316:1371-1375.
30. Glagov S. Intimal hyperplasia, vascular modeling, and the restenosis problem. Circulation. 1994;89:2888-2891.
31. Desmarais RL, Sarembock IJ, Ayers CR, Vernon SM, Powers ER, Gimple LW. Elevated serum lipoprotein(a) is a risk factor for clinical recurrence after coronary balloon angioplasty. Circulation. 1995;91:1403-1409.
32. Violaris AG, Melkert R, Serruys PW. Influence of serum cholesterol and cholesterol subfractions on restenosis after successful coronary angioplasty: a quantitative angiographic analysis of 3336 lesions. Circulation. 1994;90:2267-2279.
33. Itoh A, Miyazaki S, Nonogi H, Daikoku S, Haze K. Angioscopic prediction of successful dilatation and of restenosis in percutaneous transluminal coronary angioplasty: significance of yellow plaque. Circulation. 1995;91:1389-1396.
34. Tan K, Sulke N, Taub N, Sowton E. Clinical and lesion morphologic determinants of coronary angioplasty success and complications: current experience. J Am Coll Cardiol. 1995;25:855-865.
35. Ueda M, Becker AE, Tsukada T, Numano F, Fujimoto T. Fibro-cellular tissue response after percutaneous transluminal coronary angioplasty: an immunocytochemical analysis of the cellular composition. Circulation. 1991;83:1327-1332.