Thyroglobulin as an autoantigen: What can we learn about immunopathogenicity from the correlation of antigenic properties with protein structure?

Immunology

Volumn 112, Issue 1, 2004, Pages 13-25

  Gentile, Fabrizio ^a   Conte, Marisa ^b   Formisano, Silvestro ^b  

^a UNIVERSITY OF MOLISE   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Autoantibodies; Autoimmune thyroid disease; Epitopes; Experimental autoimmune thyroiditis; Thyroglobulin

Indexed keywords

ACETYLCHOLINESTERASE; AUTOANTIBODY; AUTOANTIGEN; CYSTEINE; EPITOPE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; PEPTIDE; PROTEINASE; RECOMBINANT PROTEIN; THYROGLOBULIN; THYROGLOBULIN ANTIBODY;

ALGORITHM; ANTIBODY RESPONSE; ANTIGEN PRESENTATION; ANTIGEN STRUCTURE; ANTIGENICITY; AUTOIMMUNE DISEASE; AUTOIMMUNITY; B LYMPHOCYTE; CELL PROLIFERATION; CORRELATION ANALYSIS; DIAGNOSTIC VALUE; DISEASE COURSE; DISEASE MODEL; ENZYME ACTIVITY; GENE LOCATION; GENETIC RECOMBINATION; GRAVES DISEASE; HASHIMOTO DISEASE; HEREDITY; HUMAN; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; IMMUNOPATHOGENESIS; IN VITRO STUDY; IN VIVO STUDY; IODINATION; ISOGRAFT; LYMPH NODE CELL; METHODOLOGY; NONHUMAN; OXIDATION; PATHOGENICITY; PEPTIDE MAPPING; PEPTIDE SYNTHESIS; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN STRUCTURE; REVIEW; SEQUENCE HOMOLOGY; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TANDEM REPEAT; THYROID DISEASE;

ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; EPITOPE MAPPING; EPITOPES, T-LYMPHOCYTE; HUMANS; MICE; STRUCTURE-ACTIVITY RELATIONSHIP; THYROGLOBULIN; THYROIDITIS, AUTOIMMUNE;

EID: 2342607993     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2004.01861.x     Document Type: Review

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