An association between the acute phase response and patterns of antigen induced T cell proliferation in juvenile idiopathic arthritis

Arthritis Research and Therapy

Volumn 5, Issue 5, 2003, Pages

  Black, Antony Pb ^a,b   Bhayani, Hansha ^a   Ryder, Clive Aj ^c   Pugh, Mark T ^d   Gardner Medwin, Janet Mm ^c   Southwood, Taunton R ^a,c  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

^d UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

acute phase response; arthritis; juvenile idiopathic arthritis; T cells

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CHEMOKINE RECEPTOR; CXC CHEMOKINE RECEPTOR 3; INTEGRIN; INTEGRIN ALPHA4BETA7; INTEGRIN ALPHAEBETA7; LYMPHOCYTE ANTIGEN RECEPTOR; STREPTOLYSIN; STREPTOLYSIN O; TETANUS TOXOID;

ACUTE PHASE RESPONSE; ADOLESCENT; ARTICLE; BIOSYNTHESIS; BLOOD; CELL DIVISION; CHEMISTRY; CHILD; CYTOLOGY; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; JUVENILE RHEUMATOID ARTHRITIS; MALE; METABOLISM; PATHOLOGY; PHENOTYPE; PHYSIOLOGY; PRESCHOOL CHILD; SYNOVIAL FLUID; T LYMPHOCYTE; TIME;

ACUTE-PHASE REACTION; ADOLESCENT; ANTIGENS, BACTERIAL; ARTHRITIS, JUVENILE RHEUMATOID; BACTERIAL PROTEINS; CELL DIVISION; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INTEGRINS; MALE; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, CHEMOKINE; STREPTOLYSINS; SYNOVIAL FLUID; T-LYMPHOCYTES; TETANUS TOXOID; TIME FACTORS;

EID: 2342584876     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar791     Document Type: Article

References (31)

1. Matthews N, Emery P, Pilling D, Akbar A, Salmon M: Subpopulations of primed T helper cells in rheumatoid arthritis. Arthritis Rheum. 1993, 36: 603-607. DOI: 10.1002/art.1780360505
2. Black AP, Bhayani H, Ryder CAJ, Gardner-Medwin JMM, Southwood TR: T-cell activation without proliferation in juvenile idiopathic arthritis. Arthritis Res. 2002, 4: 177-183. 10.1186/ar403. DOI: 10.1186/ar403
3. Silverman ED, Isacovics B, Petsche D, Laxer RM: Synovial fluid cells in juvenile arthritis: evidence of selective T cell migration to inflamed tissue. Clin Exp Immunol. 1993, 91: 90-95. DOI: 10.1111/j.1365-2249.1993.tb03360.x
4. Pitzalis C, Kingsley G, Haskard D, Panayi G: The preferential accumulation of helper-inducer T lymphocytes in inflammatory lesions: evidence for regulation by selective endothelial and homotypic adhesion. Eur J Immunol. 1988, 18: 1397-1404. DOI: 10.1002/eji.1830180915
5. Borthwick NJ, Akbar AN, Maccormac LP, Lowdell M, Craigen JL, Hassan I, Grundy JE: Selective migration of highly differentiated primed T cells, defined by low expression of CD45RB, across human umbilical vein endothelial cells: effects of viral infection on transmigration. Immunology. 1997, 90: 272-280. 10.1046/j.1365-2567.1997.00154.x. DOI: 10.1046/j.1365-2567.1997.00154.x
6. Ford DK, Da Roza DM, Schulzer M: Lymphocytes from the site of disease but not blood lymphocytes indicate the cause of arthritis. Ann Rheum Dis. 1985, 44: 701-710. DOI: 10.1136/ard.44.10.701
7. Sieper J, Braun J, Wu P, Kingsley G: T cells are responsible for the enhanced synovial cellular immune response to triggering antigen in reactive arthritis. Clin Exp Immunol. 1993, 91: 96-102. DOI: 10.1111/j.1365-2249.1993.tb03361.x
8. Petty RE, Southwood TR, Baum J, Bhetty E, Glass DN, Manners P, Maldonado-Cocco J, Suarez-Almazor M, Orozco-Alcala J, Prieur A-M: Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. J Rheumatol. 1998, 25: 1991-1994.
9. Butcher EC, Picker LJ: Lymphocyte homing and homeostasis. Science. 1996, 272: 60-66. DOI: 10.1126/science.272.5258.60
10. Sieper J, Braun J, Doring E, Wu P, Heesemann J, Treharne J, Kingsley G: Aetiological role of bacteria associated with reactive arthritis in pauciarticular juvenile chronic arthritis. Ann Rheum Dis. 1992, 51: 1208-1214. DOI: 10.1136/ard.51.11.1208
11. Life P, Hasell A, Williams K, Young S, Bacon P, Southwood T, Gaston JSH: Responses to gram negative enteric bacterial antigens. Synovial T cells from patients with juvenile chronic arthritis: recognition of Heat Shock Protein HSP 60. J Rheumatol. 1993, 20: 1388-1396.
12. Southwood TR, Gaston JSH: Evolution of synovial fluid mononuclear cell responses in a HLA B27-positive patient with Yersinia-associated juvenile arthritis. Br J Rheumatol. 1993, 32: 845-848. DOI: 10.1093/rheumatology/32.9.845
13. Schultz DR, Arnold PI: Properties of four acute phase proteins: C-reactive protein, serum amyloid A protein, α 1-acid glycoprotein, and fibrinogen. Semin Arthritis Rheum. 1990, 20: 129-147. 10.1016/0049-0172(90)90055-K. DOI: 10.1016/0049-0172(90)90055-K
14. Mortensen RF, Osmand AP, Gewurz H: Effects of C-reactive protein on the lymphoid system. J Exp Med. 1975, 141: 821-839.
15. Whisler RL, Newhouse YG, Mortensen RF: C-reactive protein reduces the promotion of human B-cell colony formation by autoreactive T4 cells and T-cell proliferation during the autol-ogous mixed-lymphocyte reaction. Cell Immunol. 1986, 102: 287-298. 10.1016/0008-8749(86)90422-3. DOI: 10.1016/0008-8749(86)90422-3
16. Vigushin DM, Pepys MB, Hawkins PN: Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease. J Clin Invest. 1993, 90: 1351-1357. DOI: 10.1172/JCI116336
17. Badolato R, Ming Wang J, Murphy WJ, Lloyd AR, Michiel DF, Bausserman LL, Kelvin DJ, Openheim JJ: Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes. J Exp Med. 1994, 180: 203-209. 10.1084/jem.180.1.203. DOI: 10.1084/jem.180.1.203
18. Badolato R, Oppenheim J: Role of cytokines, acute-phase proteins, and chemokines in the progression of rheumatoid arthritis. Semin Arthritis Rheum. 1996, 26: 526-538. 10.1016/S0049-0172(96)80041-2. DOI: 10.1016/S0049-0172(96)80041-2
19. Gabay C, Kushner I: Acute-phase proteins and other systemic responses to inflammation. N Engl J Med. 1999, 340: 448-454. 10.1056/NEJM199902113400607. DOI: 10.1056/NEJM199902113400607
20. De Benedetti F, Pignatti P, Bernasconi S, Gerloni V, Matsushima K, Caporali R, Montecucco CM, Sozzani S, Fantini F, Martini A: Interleukin 8 and monocyte chemoattractant protein-1 in patients with juvenile rheumatoid arthritis. Relation to onset types, disease activity, and synovial fluid leukocytes. J Rheumatol. 1998, 26: 425-431.
21. Lepore L, Pennesi M, Saletta S, Perticari S, Presani G, Prodan M: Study of IL-2, IL-6, TNF-alpha, IFN-gamma and IFN-beta in the serum and synovial-fluid of patients with juvenile chronic arthritis. Clin Exp Rheum. 1994, 12: 561-565.
22. Patel KD: Mechanisms of selective leukocyte recruitment from whole blood on cytokine-activated endothelial cells under flow conditions. J Immunol. 1999, 162: 6209-6216.
23. Ding Z, Xiong K, Issekutz TB: Regulation of chemokine-induced transendothelial migration of T lymphocytes by endothelial activation: differential effects on naive and memory T cells. J Leukoc Biol. 2000, 67: 825-833.
24. Salmi M, Andrew DP, Butcher EC, Jalkanen S: Dual binding capacity of mucosal immunoblasts to mucosal and synovial endothelium in humans: dissection of the molecular mechanisms. J Exp Med. 1995, 181: 137-149. 10.1084/jem.181.1.137. DOI: 10.1084/jem.181.1.137
25. Salmi M, Rajala P, Sirpa J: Homing of mucosal leukocytes to joints. J Clin Invest. 1997, 99: 2165-2172. DOI: 10.1172/JCI119389
26. Soderstrom K, Bucht A, Halapi E, Lundqvist C, Gronberg A, Nilsson E, Orsini DLM, van de Wal Y, Konig F, Hammarstrom ML, Kiessling R: High expression of Vγ 8 is a shared feature of human γδ T cells in the epithelium of the gut and in the inflamed synovial tissue. J Immunol. 1994, 152: 6017-6027.
27. + T cells with hallmarks of gut-trophism. J Immunol. 1993, 151: 717-729.
28. Farstad IN, Halstensen TS, Lien B, Kilshaw PJ, Lazarovitz AI, Brandtzaeg P: Distribution of β7 integrins in human intestinal mucosa and organized gut-associated lymphoid tissue. Immunology. 1996, 89: 227-237. 10.1046/j.1365-2567.1996.d01-727.x. DOI: 10.1046/j.1365-2567.1996.d01-727.x
29. Kilshaw PJ, Murant SJ: Expression and regulation of β7 (βp) integrins on mouse lymphocytes: relevance to the mucosal immune system. Eur J Immunol. 1991, 21: 2591-2597. DOI: 10.1002/eji.1830211041
30. Bonecchi R, Bianchi G, Bordignon PP, D'Ambrosio D, Lang R, Borsatti A, Sozzani S, Allavena P, Gray PA, Matovani A, Sinigaglia F: Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med. 1998, 187: 129-134. 10.1084/jem.187.1.129. DOI: 10.1084/jem.187.1.129
31. Wedderburn LR, Robinson N, Patel A, Varsani H, Woo P: Selective recruitment of polarized T cells expressing CCR5 and CXCR3 to the inflamed joints of children with juvenile idiopathic arthritis. Arthritis Rheum. 2000, 43: 765-774. 10.1002/1529-0131(200004)43:4<765::AID-ANR7>3.0.CO;2-B. DOI: 10.1002/1529-0131(200004)43:4<765::AID-ANR7>3.0.CO;2-B