T-cell activation without proliferation in juvenile idiopathic arthritis

Arthritis Research

Volumn 4, Issue 3, 2002, Pages 177-183

  Black, Antony P B ^a   Bhayani, Hansha ^b   Ryder, Clive A J ^c   Gardner Medwin, Janet M M ^c   Southwood, Taunton R ^b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c BIRMINGHAM CHILDREN S HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Activation; Chronic inflammation; Differentiation; T cells

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; CD69 ANTIGEN; CD71 ANTIGEN; CD8 ANTIGEN; CELL MARKER; HLA DR ANTIGEN; INTERLEUKIN 16; INTERLEUKIN 2 RECEPTOR; LYMPHOCYTE SURFACE MARKER; PROPIDIUM IODIDE;

CELL ACTIVATION; CELL CYCLE; CELL DIFFERENTIATION; CELL DIVISION; CELL ISOLATION; CELL PROLIFERATION; CHILD; CHRONIC INFLAMMATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; LYMPHOCYTE CULTURE; LYMPHOCYTE SUBPOPULATION; MALE; MONONUCLEAR CELL; PROTEIN EXPRESSION; REVIEW; SIMULATION; STAINING; SYNOVIAL FLUID; T LYMPHOCYTE ACTIVATION;

ADOLESCENT; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; ARTHRITIS, JUVENILE RHEUMATOID; BIOLOGICAL MARKERS; CELL CYCLE; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOLOGIC MEMORY; INFANT; MALE; PHENOTYPE; SYNOVIAL FLUID; T-LYMPHOCYTES;

EID: 0036236339     PISSN: 14659905     EISSN: None     Source Type: Journal    
DOI: 10.1186/ar403     Document Type: Review

References (30)

1. Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997
2. The role of infection in juvenile chronic arthritis
3. Gut inflammation in children with late onset pauciarticular juvenile chronic arthritis and evolution to adult spondyloarthropathy - A prospective study
4. Responses to gram negative enteric bacterial antigens. Synovial T cells from patients with juvenile chronic arthritis: Recognition of Heat Shock Protein HSP 60
5. Evolution of the T cells receptor β repertoire from synovial fluid T cells of patients with juvenile onset rheumatoid arthritis
6. Comparative sequence analysis of the human T cell receptor β chain in juvenile rheumatoid arthritis and juvenile spondyloarthropathies
7. Frequent enrichment for CD8 T cells reactive against common herpes viruses in chronic inflammatory lesions; towards a reassessment of the physiopathological significance of T cell clonal expansions found in processes
8. Immunohistological characteristics of T cell infiltrates in different forms of childhood onset chronic arthritis
9. Synovial fluid cells in juvenile arthritis: Evidence of selective T cell migration to inflamed tissue
10. Augmented numbers of HLA-DR-positive T lymphocytes in the synovial fluid and synovial tissue of patients with rheumatoid arthritis and juvenile rheumatoid arthritis
11. Phenotypes of T lymphocytes from peripheral blood and synovial fluid of patients with rheumatoid arthritis and juvenile rheumatoid arthritis
12. Selective recruitment of polarized T cells expressing CCR5 and CXCR3 to the inflamed joints of children with juvenile idiopathic arthritis
13. Synovial fluid lymphocytes in different subtypes of juvenile rheumatoid arthritis
14. Transferrin receptor induction by hypoxia
15. Identification of a hypoxia response element in the transferrin receptor gene
16. Molecular and functional analysis of a lymphocyte chemoattractant factor: Association of biological function with CD4 expression
17. Multiparametric flow cytometric analysis of the kinetics of surface molecule expression after polyclonal activation of human peripheral blood T lymphocytes
18. Flow cytometric analysis of activation markers on stimulated T cells and their correlation with cell proliferation
19. Expression of CD69 antigen on synovial fluid T cells in patients with rheumatoid arthritis and other chronic synovitis
20. Characterisation and regulation of CD69 expression on rheumatoid arthritis synovial fluid T cells
21. Evidence for the continuous recruitment and activation of T cells into the joints of patients with rheumatoid arthritis
22. Phenotype transition of CD4+ T cells from CD45RA to CD45RO is accompanied by cell activation and proliferation
23. T cells are responsible for the enhanced synovial cellular immune response to triggering antigen in reactive arthritis
24. Influence of hypoxia on inflammatory synovitis
25. Classification of childhood arthritis: Divide and conquer
26. Subpopulations of primed T helper cells in rheumatoid arthritis
27. The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis
28. Selective migration of highly differentiated primed T cells, defined by low expression of CD45RB, across human umbilical vein endothelial cells: Effects of viral infection on transmigration
29. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
30. high CD8+ T cells comprise both naive and memory cells