The roller coaster of antioxidant therapy

Current Medicinal Chemistry

Volumn 11, Issue 9, 2004, Pages

  Visioli, Francesco ^a,b  

^a UNIVERSITY OF MILAN   (Italy)

^b OREGON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; BIOLOGICAL MARKER; CAROTENOID; FLAVONOID; HYDROPEROXIDE; HYPOCHLOROUS ACID; LIPID; OXIDIZED LOW DENSITY LIPOPROTEIN; OXIDIZING AGENT; POLYPHENOL DERIVATIVE; RESVERATROL; THIOCTIC ACID; TOCOPHEROL DERIVATIVE;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ATHEROSCLEROSIS; CANCER; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CYTOSTASIS; DEGENERATIVE DISEASE; DIET SUPPLEMENTATION; DIETARY INTAKE; DOSE RESPONSE; DRUG ACTIVITY; DRUG FATALITY; DRUG MECHANISM; EDITORIAL; FOOD COMPOSITION; HEART DEATH; HUMAN; ISCHEMIC HEART DISEASE; LIPID PEROXIDATION; LONGEVITY; MEDICAL RESEARCH; OXIDATIVE STRESS; TREATMENT FAILURE; WINE;

EID: 2342533918     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (28)

1. Stadtman, E. Role of oxidant species in aging. Curr. Med. Chem. 2004, 11, 1105-1112.
2. Halliwell, B.; Long, L. H.:-Yee, T. P.; Lim, S.; Kelly, R. Establishing biomarkers of oxidative stress. The measurement of hydrogen peroxide in human urine. Curr. Med. Chem. 2004, 11, 1085-1092.
3. Carr, A.; Hawkins, C. L.; Thomas, S. R.; Stocker, R,; Frei, B. Relative reactivities of N-chloramines and hypochlorous acid with human plasma constituents. Free Radio Biol. Med. 2001, 30, 526-536.
4. Diplock, A. T. Will the "good fairies" please prove to us that vitamin E lessens human degenerative disease? Free Rad. Res. 1997, 27, 511-532.
5. Meagher, E. A.; Barry, O. P.; Lawson, J. A.; Rokach, J.; FitzGerald, G, A. Effects of vitamin E on lipid peroxidation in healthy persons. JAMA 2001, 285, 1178-1182.
6. Frei, B. To C or not to C, that is the question! J. Am. Coll. Cardiol. 2003, 42, 253-255.
7. Smith, A,; Shenvi, S. V, Widlansky, M.; Suh, J.; Hagen, T. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. Curr. Med. Chem. 2004, 11, 1135-1146.
8. Zingg, J. M.; Azzi, A. Non-antioxidant activities of vitamin E. Curr. Med. Chem. 2003, 11, 1113-1133.
9. Schulz, E.; Anter, E.; Keaney, J. F. Oxidative stress, antioxidants, and endothelial function. Curr. Med. Chem. 2004, 11, 1135-1146.
10. Kalayoglu, M. V.; Libby, P.; Byrne, G. I. Chlamydia pneumoniae as an emerging risk factor in cardiovascular disease, JAMA 288, 2002, 2724-2731.
11. Lee, B. M.; Park, K. K. Beneficial and adverse effects of chemopreventive agents. Mutat. Res. 523-524, 2003, 265-278.
12. Visioli, F.; Borsani, L.; Galli, C. Diet and prevention of coronary heart disease: the potential role of phytochemicals. Cardiovasc. Res. 2000, 47, 419-425.
13. Kris-Etherton, P. M.; Hecker, K. D.; Bonanome, A.; Coval. S. M.; Binkoski, A. E.; Hilpert, K. F.; Griel, A. E.; Etherton, T. D. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am. J. Med. 2002, 113 Suppl. 9B, 71-88.
14. Visioli, F.; Riso, P.; Grande, S.; Galli, C.; Porrini, M. Protective activity of tomato products on in vivo markers of lipid oxidation. Eur. J. Nutr. 2003, 42, 201-206.
15. Lachance, P. A.; Nakat, Z.; Jeong, W. S. Antioxidants; an integrative approach. Nutrition 2001, 17, 835-838.
16. Vivekananthan, D. P.; Penn, M. S.; Sapp, S. K.; Hsu, A.; Topol, E. J. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet 2003, 361, 2017-2023.
17. Paolini, M.; Cantelli-Forti, G.; Perocco, P.; Pedulli, G. F.; Abdel-Rahman, S. Z.; Legator, M. S. Co-carcinogenic effect of beta-carotene. Nature 1999, 398, 760-761.
18. Visioli, F.; Rise, P.; Barassi, M.; Marangoni, F.; Galli, C. Dietary intake of fish, vs. formulations, leads to higher plasma concentrations of n-3 fatty acids. Lipids 2003, 38, 415-418.
19. Visioli, F.; Galli, C, Grande, S.; Colonnelli, K.; Patelli, C.; Galli, G.; Caruso, D. Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration. J. Nutr. 2003, 133, 2612-2615.
20. Frei, B.; Higdon, J. V. Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. J. Nutr. 2003, 133, 3275S-3284S.
21. Klatsky, A. L; Friedman, G. D.; Armstrong, M. A.; Kipp, H. Wine, liquor, beer, and mortality. Am. J. Epidemiol. 2003, 158, 585-595.
22. Soleas, G. J.; Diamandis, E. P.; Goldberg, D. M. Wine as a biological fluid: history, production, and role in disease prevention. J. Clin. Lab. Anal. 1997, 11, 287-313.
23. de Vries, J, H.; Hollman, P. C.; van, A., I; Olthof, M. R, Katan, M. B. Red wine is a poor source of bioavailable flavonols in men. J. Nutr. 2001, 131, 745-748.
24. Goldberg, D. M.; Yan, J.; Soleas, G. J. Absorption of three wine-related polyphenols in three different matrices by healthy subjects, Clin. Biochem. 2003, 36, 79-87.
25. Natella, F.; Ghiselli, A.; Guidi, A.; Ursini, F.; Scaccini, C. Red wine mitigates the postprandial increase of LDL susceptibility to oxidation. Free Radic. Biol. Med. 2001, 30, 1036-1044.
26. Kanner, J.; Lapidot, T. The stomach as a bioreactor: dietary lipid peroxidation in the gastric fluid and the effects of plant-derived antioxidants. Free Radic. Biol. Med. 2001, 31, 1388-1395
27. Poli, G.; Leonarduzzi, G.; Biasi, F.; Chiarpotto, E. Oxidative stress and cell signalling. Curr. Med. Chem. 2004, 11, 1163-1182.
28. Cuzzocrea, S.; Thiemermann, C.; Salvemini, D. Potential therapeutic effect of antioxidant therapy in shock and inflammation. Curr. Med. Chem. 2004, 11, 1147-1162.