Differential Expression of Homer Family Proteins in the Developing Mouse Brain

Journal of Comparative Neurology

Volumn 473, Issue 4, 2004, Pages 582-599

  Shiraishi, Yoko ^a   Mizutani, Akihiro ^a   Yuasa, Shigeki ^b   Mikoshiba, Katsuhiko ^a   Furuichi, Teiichi ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

Cerebellum; Hippocampus; Homer Cupidin; Olfactory bulb; Postsynaptic density

Indexed keywords

ADAPTOR PROTEIN; HOMER 1B PROTEIN; HOMER 1C PROTEIN; HOMER 2A PROTEIN; HOMER 2B PROTEIN; HOMER 3A PROTEIN; HOMER 3B PROTEIN; HOMER PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN REGION; CEREBELLUM; CILIARY BODY; CONTROLLED STUDY; DENDRITIC SPINE; DOWN REGULATION; GRANULAR CELL; GRANULE CELL; HIPPOCAMPUS; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MEDULLA OBLONGATA; MOUSE; NERVE FIBER; NONHUMAN; OLFACTORY BULB; OLFACTORY EPITHELIUM; PERINATAL DEVELOPMENT; PONS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PURKINJE CELL; REGULATORY MECHANISM; RHOMBENCEPHALON; SENSORY NERVE CELL; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BRAIN; CARRIER PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, INBRED ICR; NEUROPEPTIDES;

EID: 2342483173     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/cne.20116     Document Type: Article

References (37)

1. Ango F, Pin J-P, Tu JC, Xiao B, Worley PF, Bockaert J, Fagni L. 2000. Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by Homerl proteins and neuronal excitation. J Neurosci 20:8710-8716.
2. Ango F, Prezeau L, Muller T, Tu JC, Xiao B, Worley PF, Pin JP, Fagni L. 2001. Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer. Nature 411:962-965.
3. Ango F, Robbe D, Tu JC, Xiao B, Worley PF, Pin J-P, Bockaert J, Fagni L 2002. Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons. Mol Cell Neurosci 20:323-329.
4. Brakeman PR, Lanahan AA, O'Brien R, Roche K, Barnes CA, Huganir RL, Worley PF. 1997. Nature Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 386:284-288.
5. Brann JH, Dennis JC, Morrison EE, Fadool DA. 2003. Type-specific inositol 1,4,5-trisphosphate receptor localization in the vomeronasal organ and its interaction with a transient receptor potential channel, TRPC2. J Neurochem 83:1452-1460.
6. Ciruela F, Soloviev MM, McIlhinney RAJ. 1999. Co-expression of metabotropic glutamate receptor type 1α with Homer-1a/Vesl-1S increases the cell surface expression of the receptor. Biochem J 341:795-803.
7. Ciruela F, Soloviev MM, Chan W-Y, McIlhinney RAJ. 2000. Homer-1c/ Vesl-1L modulates the cell surface targeting of metabotropic glutamate receptor type 1α evidence for an anchoring function. Mol Cell Neurosci 15:36-50.
8. Diagana TT, Thomas U, Prokopenko SN, Xiao B, Worely PF, Thomas JB. 2002. Mutation of Drosophila homer disrupts control of locomotor activity and behavioral plasticity. J Neurosci 22:428-436.
9. Foa L, Rajan I, Haas K, Wu G-Y, Brakeman P, Worely P, Cline H. 2001. The scaffold protein, Homer1b/c, regulates axon pathfinding in the central nervous system in vivo. Nat Neurosci 4:499-506.
10. 2+ signaling in the brain. J Neurochem 64:953-960.
11. Kammermeier PJ, Xiao B, Tu JC, Worely PF, Ikeda SR. 2000. Homer proteins regulate coupling of group I metabotropic glutamate receptors to N-type calcium and M-type potassium channels. J Neurosci 20:7238-7245.
12. Kato A, Ozawa F, Saitoh Y, Hirai K, Inokuchi K, 1997. vesl, a gene encoding VASP/Ena family related proteins, is up-regulated during seizure, long-term potentiation and synaptogenesis. FEBS 412:183-189.
13. Kato A, Ozawa F, Saitoh Y, Fukazawa Y, Sugiyama H, Inokuchi K. 1998. Novel members of the vesl/Homer family of PDZ proteins that bind metabotropic glutamate receptors. J Biol Chem 273:23969-23975.
14. Maeda N, Niinobe M, Nakahira K, Mikoshiba K. 1988. Purification and characterization of P400 protein, a glycoprotein characteristic of Purkinje cells, from mouse cerebellum. J Neurochem 51:1724-1730.
15. Maeda N, Kawasaki T, Nakade S, Yokota N, Taniguchi T, Kasai M, Mikoshiba K. 1991. Structural and functional characterization of inositol 1,4,5-trisphosphate receptor channel from mouse cerebellum. J Biol Chem 266:1109-1116.
16. Miyawaki A, Matsushita F, Ryo Y, Mikoshiba K. 1994. Possible pheromone-carrier function of two lipecalin proteins in the vomeronasal organ. EMBO J 13:5835-5842.
17. Naisbitt S, Kim E, Tu JC, Xiao B, Sala C, Valtschanoff J, Weinberg RJ, Worley PF, Sheng M. 1999. Shank, a novel family of postsynaptic density protein that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin. Neuron 23:569-582.
18. Nakanishi S, Maeda N, Mikoshiba K. 1991. Immunohistochemical localization of an inositol 1,4,5-trisphosphate receptor, P400, in neural tissue: studies in developing and adult mouse brain. J Neurosci 11:2075-2086.
19. Okabe S, Urushido T, Konno D, Okado H, Sobue K. 2001. Rapid redistribution of the postsynaptic density protein PSD-Zip45 (Homer 1c) and its differential regulation by NMDA receptors and calcium channels. J Neurosci 21:9561-9571.
20. Petralia RS, Wang Y-X, Sans N, Worley PF, Hammer JA III, Wenthold RJ. 2001. Glutamate receptor targeting in the postsynaptic spine involves mechanisms that are independent of myosin Va. Eur J Neurosci 13:1722-1732.
21. Roche KW, Tu JC, Petralia RS, Xiao B, Wenthold RJ, Worley PF. 1999. Homer 1b regulates the trafficking of group I metabotropic glutamate receptors. J Biol Chem 274:25953-25957.
22. Saito H, Kimura M, Inanobe A, Ohe T, Kurachi Y. 2002. An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells. Biochem Biophys Res Commun 296:523-529.
23. Sala C, Piech V, Wilson NR, Passafaro M, Liu G, Sheng M. 2001. Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron 31:115-130.
24. Sato M, Suzuki K, Nakanishi S. 2001. NMDA receptor stimulation and brain-derived neurotrophic factor up-regulate Homer 1a mRNA via the mitogen-activated protein kinase cascade in cultured cerebellar granule cells. J Neurosci 21:3793-3805.
25. Shiraishi Y, Mizutani A, Bito H, Fujisawa K, Narumiya S, Mikoshiba K, Furuichi T. 1999. Cupidin, an isoform of Homer/Vesl, interacts with the actin cytoskeleton and activated rho family small GTPases and is expressed in developing mouse cerebellar granule cells. J Neurosci 19:8389-8400.
26. Shiraishi Y, Mizutani A, Mikoshiba K, Furuichi T. 2003a. Coincidence in dendritic and synaptic targeting of homer proteins and NMDA receptor proteins NR2B and PSD95 during development of cultured hippocampal neurons. Mol Cell Neurosci 22:188-201.
27. Shiraishi Y, Mizutani A, Yuasa S, Mikoshiba K, Furuichi T. 2003b. Glutamate-induced declustering of postsynaptic adaptor protein Cupidin (Homer 2/vesl-2) in cultured cerebellar granule cells. J Neurochem 87:364-376.
28. Soloviev MM, Ciruela F, Chan W-Y, McIllhinney RAJ. 2000a. Mouse brain and muscle tissues constitutively express high levels of Homer proteins. Eur J Biochem 267:634-639.
29. Soloviev MM, Ciruela F, Chan W-Y, McIlhinney RAJ. 2000b. Molecular characterization of two structurally distinct groups of human Homers, generated by extensive alternative splicing. J Mol Biol 295:1186-1200.
30. Sun J, Tadokoro S, Imanaka T, Murakami SD, Nakamura M, Kashiwada K, Ko J, Nishida W, Sobue K. 1998. Isolation of PSD-Zip45, a novel Homer/vesl family protein containing leucine zipper motifs, from rat brain. FEBS Lett 437:304-308.
31. Tadokoro S, Tachibana T, Imanaka T, Nishida W, Sobue K. 1999. Involvement of leucine-zipper motif of PSD-Zip45 (Homer 1c/vesl-1L) in group 1 metabotropic glutamate receptor clustering. Proc Natl Acad Sci USA 96:13801-13806.
32. Treloar EB, Ganeau D, Yoshihara Y, Mori K, Greer CA. 2003. Inverse expression of olfactory cell adhesion molecule in a subset of olfactory axons and a subset of mitral/tufted cells in the developing rat main olfactory bulb. J Comp Neurol 458:389-403.
33. 3 receptors. Neuron 21:717-726.
34. Tu JC, Xiao B, Naisbitt S, Yuan JP, Petralia RS, Brakeman P, Doan A, Aakalu VK, Lanahan AA, Sheng M, Worely PF. 1999. Coupling of mGluR/Homer and PSD95 complexes by the Shank family of postsynaptic density proteins. Neuron 23:583-592.
35. Xiao B, Tu JC, Petralia RS, Yuan JP, Doan A, Breder CD, Ruggiero A, Lanahan AA, Wenthold RJ, Worley PF. 1998. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of Homer-related, synaptic proteins. Neuron 21:707-716.
36. Yoshihara Y, Kawasaki M, Tamada A, Fujita H, Hayashi H, Kagamiyama H, Mori K. 1997. OCAM: a new member of the neural cell adhesion molecule family related to zone-to-zone projection of olfactory and vomeronasal axons. J Neurosci 17:5830-5842.
37. 3 receptors. Cell 114:777-789.