Study of an antioxidant drug karinat in patients with chronic atrophic gastritis

Voprosy Onkologii

Volumn 50, Issue 1, 2004, Pages 81-85

  Bespalov, V G ^a   Sherbakov, A M ^a   Kalinovsky, V P ^a   Novik, V I ^a   Chepik, O F ^a   Alexandrov, V A ^a   Sobenin, I A ^b   Orekhov, A N ^b  

^a N N PETROV RESEARCH INSTITUTE OF ONCOLOGY   (Russian Federation)

^b RAEN   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; GARLIC EXTRACT; KARINAT; PLACEBO; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; PLANT EXTRACT;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ATROPHIC GASTRITIS; CANCER RISK; CHRONIC GASTRITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIGESTION; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; EPITHELIZATION; GARLIC; GASTROINTESTINAL INFECTION; GASTROSCOPY; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; INTESTINE METAPLASIA; MAJOR CLINICAL STUDY; MITOSIS INHIBITION; STATISTICAL SIGNIFICANCE; STOMACH CARCINOGENESIS; STOMACH CARCINOMA; TABLET FORMULATION; CHRONIC DISEASE; DOUBLE BLIND PROCEDURE; DRUG COMBINATION; FEMALE; MALE; MICROBIOLOGY; MIDDLE AGED; PHASE 2 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; STOMACH TUMOR; TREATMENT OUTCOME;

ALPHA-TOCOPHEROL; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; ASCORBIC ACID; BETA CAROTENE; CHRONIC DISEASE; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; FEMALE; GARLIC; GASTRITIS, ATROPHIC; HELICOBACTER INFECTIONS; HUMANS; MALE; MIDDLE AGED; PLANT EXTRACTS; STOMACH NEOPLASMS; TREATMENT OUTCOME;

EID: 2342478493     PISSN: 05073758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Akyon Y. Effect of antioxidants on the immune response of Helicobacter pylori // Clin. Microbiol. Infect. - 2002. - Vol. 8. - P. 438-441.
2. Beno I., Klvanova J., Magalova T., Brtkova A. Blood levels of natural antioxidants in gastric and colorectal precancerous lesions and cancers in Slovakia // Neoplasma. - 2000. - Vol. 47. - P. 37-40.
3. Bukin Y.V., Draudin-Krylenko V.A., Kuvshinov Y.P. et al. Decrease of ornithine decarboxylase activity in pre-malignant gastric mucosa and regression of small intestinal metaplasia in patients supplemented with high doses of vitamin E // Cancer Epidemiol. Biomarkers Prev. - 1997. - Vol. 6. - P. 543-546.
4. Bukin Y.V., Zaridze D.G., Draudin-Krylenko V.A. et al. Effect of beta-carotene supplementation on the activity of ornithine decarboxylase (ODC) in stomach mucosa of patients with chronic atrophic gastritis // Europ. J. Cancer Prev. - 1993. - Vol. 2. - P. 61-68.
5. Correa P., Fontham E.T., Bravo J.C. et al. Chemoprevention of gastric dysplasia: randomized trial of antioxidant supplements and anti-Helicobacter pylori therapy // J. Natl. Cancer Inst. - 2000. - Vol. 92. - P. 1881-1888.
6. Dawsey S.M., Wang G.Q., Taylor P.R. et al. Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: results from the Dysplasia Trial in Linxian, China // Cancer Epidemiol. Biomarkers Prev. - 1994. - Vol. 3. - P. 167-172.
7. Ekstrom A.M., Serafini M., Nyren O. et al. Dietary antioxidant intake and the risk of cardia cancer and noncardia cancer of the intestinal and diffuse types: a population-based case-control study in Sweden // Int. J. Cancer. - 2000. - Vol. 87. - P. 133-140.
8. Fleischauer A.T., Arab L. Garlic and cancer: a critical review of the epidemiologic literature // J. Nutr. - 2001. - Vol. 131 (Suppl. 3). - P. 1032-1040.
9. Jacobs E.J., Connell C.J., McCullough M.L. et al. Vitamin C, vitamin E, and multivitamin supplement use and stomach cancer mortality in the Cancer Prevention Study II cohort // Cancer Epidemiol. Biomarkers Prev. - 2002. - Vol. 11. - P. 35-41.
10. Palli D., Russo A., Decarli A. Dietary patterns, nutrient intake and gastric cancer in a high-risk area of Italy // Cancer Causes. Control. - 2001. - Vol. 12. - P. 163-172.
11. Sivam G.P. Protection against Helicobacter pylori and other bacterial infections by garlic // J. Nutr. - 2001. - Vol. 131 (Suppl. 3). - P. 1106-1108.
12. Takezaki T., Gao C.M., Ding J.H. et al. Comparative study of lifestyles of residents in high and low risk areas for gastric cancer in Jiangsu Province, China; with special reference to allium vegetables // J. Epidemiol. - 1999. - Vol. 9. - P. 297-305.
13. You W.C., Zhang L., Gail M.H. et al. Helicobacter pylori infection, garlic intake and precancerous lesions in a Chinese population at low risk of gastric cancer // Int. J. Epidemiol. - 1998. - Vol. 27. - P. 941-944.
14. Zhang Z.W., Abdullahi M., Farthing M.J. Effect of physiological concentrations of vitamin C on gastric cancer cells and Helicobacter pylori // Gut. - 2002. - Vol. 50. - P. 165-169.